PL1768657T3 - Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowych - Google Patents
Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowychInfo
- Publication number
- PL1768657T3 PL1768657T3 PL05758777T PL05758777T PL1768657T3 PL 1768657 T3 PL1768657 T3 PL 1768657T3 PL 05758777 T PL05758777 T PL 05758777T PL 05758777 T PL05758777 T PL 05758777T PL 1768657 T3 PL1768657 T3 PL 1768657T3
- Authority
- PL
- Poland
- Prior art keywords
- retinyl
- derivates
- compositions
- methods
- ophthalmic conditions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/164—Retinal disorders, e.g. retinopathy
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58229304P | 2004-06-23 | 2004-06-23 | |
| US62969504P | 2004-11-19 | 2004-11-19 | |
| US66090405P | 2005-03-11 | 2005-03-11 | |
| US67240505P | 2005-04-18 | 2005-04-18 | |
| PCT/US2005/020080 WO2006007314A1 (en) | 2004-06-23 | 2005-06-06 | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
| EP05758777A EP1768657B1 (en) | 2004-06-23 | 2005-06-06 | Methods and compositions for treating ophthalmic conditions with retinyl derivates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1768657T3 true PL1768657T3 (pl) | 2009-01-30 |
Family
ID=34981643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05758777T PL1768657T3 (pl) | 2004-06-23 | 2005-06-06 | Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowych |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US8314152B2 (pl) |
| EP (3) | EP1768657B1 (pl) |
| JP (1) | JP4855396B2 (pl) |
| KR (1) | KR100862930B1 (pl) |
| AR (1) | AR049929A1 (pl) |
| AT (1) | ATE404188T1 (pl) |
| AU (1) | AU2005262558B8 (pl) |
| BR (1) | BRPI0512569A (pl) |
| CA (1) | CA2569691C (pl) |
| CY (1) | CY1110435T1 (pl) |
| DE (1) | DE602005008970D1 (pl) |
| DK (1) | DK1768657T3 (pl) |
| EA (1) | EA011864B1 (pl) |
| ES (1) | ES2313368T3 (pl) |
| GE (1) | GEP20084520B (pl) |
| IL (1) | IL179872A (pl) |
| LV (1) | LV13564B (pl) |
| MX (1) | MXPA06014978A (pl) |
| NO (1) | NO20070408L (pl) |
| NZ (1) | NZ551955A (pl) |
| PL (1) | PL1768657T3 (pl) |
| PT (1) | PT1768657E (pl) |
| SG (1) | SG140607A1 (pl) |
| SI (1) | SI1768657T1 (pl) |
| TW (1) | TWI396532B (pl) |
| WO (1) | WO2006007314A1 (pl) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3326623A1 (en) | 2003-03-14 | 2018-05-30 | University of Washington | Retinoid replacements and opsin agonists and methods for the use thereof |
| JP2007525496A (ja) * | 2004-02-17 | 2007-09-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 黄班変性症を含む眼科疾患の管理 |
| EP1722766A2 (en) | 2004-02-17 | 2006-11-22 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| KR20140140616A (ko) | 2004-06-18 | 2014-12-09 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 시각 이상 치료를 위한 레티날 유도체 및 이를 이용하기 위한 방법 |
| PL1768657T3 (pl) | 2004-06-23 | 2009-01-30 | Revision Therapeutics Inc | Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowych |
| US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| WO2006033734A2 (en) * | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| CN101048139A (zh) * | 2004-10-28 | 2007-10-03 | 艾德克斯实验室公司 | 药物活性化合物的控释组合物 |
| KR20070091283A (ko) * | 2004-11-04 | 2007-09-10 | 시리온 테라퓨틱스, 인크. | 레티놀-레티놀 결합단백질(rbp)-트랜스타이레틴(ttr) 복합체 형성의조절 인자 |
| BRPI0520207A2 (pt) * | 2004-12-08 | 2012-09-25 | Revision Therapeutics Inc | uso de uma quantidade eficaz de um primeiro composto, e, medicamento sistemicamente formulado |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| US8114440B2 (en) * | 2005-11-16 | 2012-02-14 | Idexx Laboratories Inc. | Pharmaceutical compositions for the administration of aptamers |
| US7754679B2 (en) * | 2005-11-16 | 2010-07-13 | Idexx Laboratories, Inc. | Pharmaceutical compositions for the administration of aptamers |
| CN101500594A (zh) * | 2006-06-22 | 2009-08-05 | 西来昂诊疗公司 | 通过调节巨蛋白活性治疗眼病的方法和组合物 |
| CA2657015A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Opsin stabilizing compounds and methods of use |
| CA2657238A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic disease |
| CA2657164A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic light toxicity |
| US8828960B2 (en) * | 2007-07-17 | 2014-09-09 | Idexx Laboratories, Inc. | Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds |
| KR101810381B1 (ko) | 2008-02-11 | 2017-12-19 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 연령-관련 망막 기능장애의 치료 및 예방 방법 |
| US8460635B2 (en) * | 2008-03-12 | 2013-06-11 | Albert Einstein College Of Medicine Of Yeshiva University | Fenretinide derivatives and uses thereof as therapeutic, diagnostic and imaging agents |
| WO2010008995A2 (en) * | 2008-07-14 | 2010-01-21 | Otonomy, Inc. | Controlled-release apoptosis modulating compositions and methods for the treatment of otic disorders |
| ES2549916T3 (es) * | 2009-05-04 | 2015-11-03 | Acucela, Inc. | Composiciones para usar en el tratamiento de glaucoma o hipertensión ocular |
| IN2012DN00352A (pl) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
| MX2012003220A (es) | 2009-09-15 | 2012-08-03 | Quadra Logic Tech Inc | Formulaciones farmaceuticas que comprenden 9-cis-retinil esteres en un vehiculo de lipido. |
| EP2509596B1 (en) | 2009-12-08 | 2019-08-28 | Case Western Reserve University | Gamma aminoacids for treating ocular disorders |
| WO2011132084A2 (en) * | 2010-04-19 | 2011-10-27 | Qlt Inc. | Therapeutic regimen and method for treating or ameliorating visual disorders associated with an endogenous retinoid deficiency |
| JP6126118B2 (ja) | 2011-11-30 | 2017-05-10 | ビカム ファーマスーティカルス,インコーポレイテッド | オプシン結合性リガンド、組成物、及び使用方法 |
| US10058616B2 (en) * | 2012-02-10 | 2018-08-28 | Tlc Biopharmaceuticals, Inc. | Pharmaceutical compositions to reduce complications of ocular steroid |
| MX389866B (es) | 2012-03-01 | 2025-03-20 | Retinagenix LLC | El uso de 9-cis-retinil acetato para mejorar la funcion visual de un sujeto que padece de perdida de la funcion visual originada por una deficiencia retinoide endogena de 11-cis retinal. |
| US8877183B2 (en) | 2012-06-26 | 2014-11-04 | National Institutes Of Health (Nih) | Methods for treatment of ocular diseases |
| US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
| WO2015184453A1 (en) * | 2014-05-30 | 2015-12-03 | Case Western Reserve University | Retinylamine derivitives for treatment of ocular disorders |
| RS61504B1 (sr) | 2014-10-24 | 2021-03-31 | Takeda Pharmaceuticals Co | Jedinjenja heteroarila za lečenje oftalmičkih bolesti |
| JP2017538728A (ja) * | 2014-12-19 | 2017-12-28 | ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. | イオントフォレシスを用いた生物活性分子の眼内送達 |
| US10449090B2 (en) | 2015-07-31 | 2019-10-22 | Allotex, Inc. | Corneal implant systems and methods |
| EP3416622B1 (en) * | 2016-02-15 | 2023-06-28 | Kemin Industries, Inc. | Positively charged liposomes as lipophilic molecule carriers |
| US11395853B2 (en) * | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
| KR102713615B1 (ko) | 2016-12-05 | 2024-10-04 | 더 잭슨 래보라토리 | 인간에서의 신경퇴화 및 녹내장에 대한 진단적 마커로서의 망막 및 시신경 내 지방 알갱이 |
| US11931327B2 (en) | 2017-07-04 | 2024-03-19 | Daiichi Sankyo Company, Limited | Drug for retinal degenerative disease associated with photoreceptor degeneration |
| EP3965747A4 (en) * | 2019-05-06 | 2023-06-07 | The Regents of the University of California | MATERIALS AND METHODS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION |
| FR3105790B1 (fr) * | 2019-12-26 | 2022-01-14 | Biophytis | Composés chimiques ciblant l’œil et leur utilisation dans le traitement de maladies oculaires |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190594A (en) | 1975-11-03 | 1980-02-26 | Johnson & Johnson | Retinoic acid derivatives |
| US4323581A (en) | 1978-07-31 | 1982-04-06 | Johnson & Johnson | Method of treating carcinogenesis |
| US4665098A (en) | 1985-03-28 | 1987-05-12 | Mcneilab, Inc. | Pharmaceutical composition of N-(4-hydroxyphenyl) retinamide having increased bioavailability |
| US4874795A (en) | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| US4673044A (en) * | 1985-08-02 | 1987-06-16 | Eastman Christensen Co. | Earth boring bit for soft to hard formations |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US4682663A (en) * | 1986-02-18 | 1987-07-28 | Reed Tool Company | Mounting means for cutting elements in drag type rotary drill bit |
| US4743400A (en) | 1986-09-22 | 1988-05-10 | Mcneilab, Inc. | Process for preparing retinoyl chlorides |
| WO1991001745A1 (en) | 1989-07-28 | 1991-02-21 | Sloan-Kettering Institute For Cancer Research | Growth factors containing vitamin a or other retinoids and uses thereof |
| US5814612A (en) | 1991-04-09 | 1998-09-29 | Sloan-Kettering Institute For Cancer Research | Retinol derivatives and uses thereof |
| US6506917B1 (en) | 1991-12-18 | 2003-01-14 | The Salk Institute For Biological Studies | Compounds and compositions useful for modulation of processes mediated by RXR |
| US6050354A (en) * | 1992-01-31 | 2000-04-18 | Baker Hughes Incorporated | Rolling cutter bit with shear cutting gage |
| US5314909A (en) | 1993-03-17 | 1994-05-24 | Merck & Co., Inc. | Use of non-steroidal antiiflammatory agents in macular degeneration |
| US5399757A (en) | 1993-07-20 | 1995-03-21 | Ortho Pharmaceutical Corporation | Process for the preparation of N-(4-hydroxyphenyl)-retinamide |
| US5824685A (en) | 1995-02-01 | 1998-10-20 | The Johns Hopkins University School Of Medicine | Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists |
| US5596011A (en) | 1995-04-06 | 1997-01-21 | Repine; Karen M. | Method for the treatment of macular degeneration |
| US5702357A (en) * | 1995-06-07 | 1997-12-30 | Cobe Laboratories, Inc. | Extracorporeal blood processing methods and apparatus |
| US5706906A (en) * | 1996-02-15 | 1998-01-13 | Baker Hughes Incorporated | Superabrasive cutting element with enhanced durability and increased wear life, and apparatus so equipped |
| US5758733A (en) * | 1996-04-17 | 1998-06-02 | Baker Hughes Incorporated | Earth-boring bit with super-hard cutting elements |
| US5846220A (en) | 1996-04-30 | 1998-12-08 | Medtronic, Inc. | Therapeutic method for treatment of Alzheimer's disease |
| US6034211A (en) | 1996-06-03 | 2000-03-07 | Kelly; Jeffery W. | β-sheet nucleating peptidomimetics |
| GB9621217D0 (en) * | 1996-10-11 | 1996-11-27 | Camco Drilling Group Ltd | Improvements in or relating to preform cutting elements for rotary drill bits |
| AU5727798A (en) | 1996-12-23 | 1998-07-17 | Texas A & M University, The | Anti-amyloidogenic agents |
| US5955305A (en) | 1997-04-28 | 1999-09-21 | Incyte Pharmaceuticals, Inc. | Human retinoid binding protein |
| US5776915A (en) | 1997-08-12 | 1998-07-07 | Clarion Pharmaceuticals Inc. | Phosphocholines of retinoids |
| CZ300929B6 (cs) | 1997-08-15 | 2009-09-16 | Duke University | Sloucenina pro použití pri lécení nebo prevenci estrogenem stimulované rakoviny |
| AU3980499A (en) | 1998-05-11 | 1999-11-29 | Endowment for Research in Human Biology, Inc., The | Use of neomycin for treating angiogenesis-related diseases |
| US7229961B2 (en) | 1999-08-24 | 2007-06-12 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into ocular tissues |
| US6669951B2 (en) | 1999-08-24 | 2003-12-30 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| EP1216221A2 (en) | 1999-09-14 | 2002-06-26 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
| WO2001038344A2 (en) | 1999-11-23 | 2001-05-31 | Gerhart Graupner | Modulation of signal transduction |
| US20020031539A1 (en) | 2000-08-30 | 2002-03-14 | The Brigham And Women's Hospital, Inc. | Oxidized forms of retinoic acid as ligands for peroxisome proliferator activated receptor gamma |
| WO2002032413A2 (en) | 2000-10-17 | 2002-04-25 | Board Of Regents, The University Of Texas System | A method to incorporate n-(4-hydroxyphenyl) retinamide in liposomes |
| US6408958B1 (en) * | 2000-10-23 | 2002-06-25 | Baker Hughes Incorporated | Superabrasive cutting assemblies including cutters of varying orientations and drill bits so equipped |
| WO2002058689A1 (en) | 2000-12-05 | 2002-08-01 | Childrens Hospital Los Angeles | Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same |
| US20030032078A1 (en) | 2001-01-23 | 2003-02-13 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of macular and retinal degenerations |
| JP2004526807A (ja) | 2001-05-29 | 2004-09-02 | ケビジェン カンパニー リミテッド | 新規のレチノイド誘導体及びその製造方法並びにその化合物を含有する抗癌剤組成物 |
| DE60208792T2 (de) | 2001-06-22 | 2006-08-31 | Merck & Co., Inc. | Tyrosin-kinase inhibitoren |
| AU2002316593A1 (en) | 2001-07-06 | 2003-01-21 | The Ohio State University Research Foundation | Solid phase synthesis of arylretinamides |
| WO2003007944A1 (en) | 2001-07-20 | 2003-01-30 | Qlt, Inc. | Treatment of macular edema with photodynamic therapy |
| US20030229062A1 (en) | 2001-12-07 | 2003-12-11 | The Regents Of The University Of California | Treatments for age-related macular degeneration (AMD) |
| US20040014131A1 (en) | 2002-07-09 | 2004-01-22 | Pfizer Inc. | Assay methods |
| AU2003301813A1 (en) | 2002-10-30 | 2004-06-07 | University Of Kentucky Research Foundation | Methods and animal model for analyzing age-related macular degeneration |
| US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| JP2006514094A (ja) | 2002-11-29 | 2006-04-27 | ゲーペーツェー バイオテック アクチェンゲゼルシャフト | C型肝炎ウイルス感染に対して有用な製剤 |
| SI21392A (sl) | 2002-12-24 | 2004-06-30 | Vinko Kunc | Postopek za avtomatsko nastavitev ojačenja izpraševalnikovega sprejemnika v brezkontaktnem identifikacijskem sistemu |
| CA2513260C (en) | 2003-01-31 | 2013-01-08 | Childrens Hospital Los Angeles | Oral compositions of fenretinide having increased bioavailability and methods of using the same |
| FI20030426L (fi) | 2003-03-24 | 2004-09-25 | Tomi Jaervinen | Syklodekstriinikompleksit |
| US7178609B2 (en) * | 2003-08-19 | 2007-02-20 | Baker Hughes Incorporated | Window mill and drill bit |
| JP4869942B2 (ja) | 2003-12-11 | 2012-02-08 | ベス・イスラエル・ディーコネス・メディカル・センター,インコーポレイテッド | インスリン感受性/抵抗性、糖尿病および肥満におけるrbp4 |
| WO2005077176A1 (en) | 2004-02-11 | 2005-08-25 | The Trustees Of Columbia University In The City Of New York | Anthocyanin compounds and methods of use thereof |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| EP1722766A2 (en) * | 2004-02-17 | 2006-11-22 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| NZ550340A (en) | 2004-03-17 | 2010-08-27 | Lars Michael Larsen | Prevention of retinopathy by inhibition of the visual cycle using a retinoid |
| KR20140140616A (ko) | 2004-06-18 | 2014-12-09 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 시각 이상 치료를 위한 레티날 유도체 및 이를 이용하기 위한 방법 |
| PL1768657T3 (pl) | 2004-06-23 | 2009-01-30 | Revision Therapeutics Inc | Sposoby i kompozycje do leczenia stanów ocznych za pomocą pochodnych retinylowych |
| US7286860B2 (en) | 2004-07-23 | 2007-10-23 | Dyna Llc | Systems and methods for a comfortable wireless communication device |
| WO2006033734A2 (en) | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| KR20070091283A (ko) | 2004-11-04 | 2007-09-10 | 시리온 테라퓨틱스, 인크. | 레티놀-레티놀 결합단백질(rbp)-트랜스타이레틴(ttr) 복합체 형성의조절 인자 |
| BRPI0520207A2 (pt) | 2004-12-08 | 2012-09-25 | Revision Therapeutics Inc | uso de uma quantidade eficaz de um primeiro composto, e, medicamento sistemicamente formulado |
| UA81382C2 (en) | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding |
-
2005
- 2005-06-06 PL PL05758777T patent/PL1768657T3/pl unknown
- 2005-06-06 SI SI200530415T patent/SI1768657T1/sl unknown
- 2005-06-06 SG SG200801546-3A patent/SG140607A1/en unknown
- 2005-06-06 JP JP2007518098A patent/JP4855396B2/ja not_active Expired - Fee Related
- 2005-06-06 DE DE602005008970T patent/DE602005008970D1/de not_active Expired - Lifetime
- 2005-06-06 CA CA2569691A patent/CA2569691C/en not_active Expired - Fee Related
- 2005-06-06 EP EP05758777A patent/EP1768657B1/en not_active Expired - Lifetime
- 2005-06-06 MX MXPA06014978A patent/MXPA06014978A/es active IP Right Grant
- 2005-06-06 KR KR1020077001270A patent/KR100862930B1/ko not_active Expired - Fee Related
- 2005-06-06 AT AT05758777T patent/ATE404188T1/de active
- 2005-06-06 PT PT05758777T patent/PT1768657E/pt unknown
- 2005-06-06 BR BRPI0512569-3A patent/BRPI0512569A/pt not_active IP Right Cessation
- 2005-06-06 WO PCT/US2005/020080 patent/WO2006007314A1/en not_active Ceased
- 2005-06-06 AU AU2005262558A patent/AU2005262558B8/en not_active Ceased
- 2005-06-06 EP EP10181656A patent/EP2277516A1/en not_active Withdrawn
- 2005-06-06 DK DK05758777T patent/DK1768657T3/da active
- 2005-06-06 NZ NZ551955A patent/NZ551955A/en not_active IP Right Cessation
- 2005-06-06 EP EP08014275A patent/EP2025336A1/en not_active Withdrawn
- 2005-06-06 EA EA200700109A patent/EA011864B1/ru not_active IP Right Cessation
- 2005-06-06 GE GEAP20059816A patent/GEP20084520B/en unknown
- 2005-06-06 ES ES05758777T patent/ES2313368T3/es not_active Expired - Lifetime
- 2005-06-10 US US11/150,641 patent/US8314152B2/en not_active Expired - Fee Related
- 2005-06-21 AR ARP050102545A patent/AR049929A1/es not_active Application Discontinuation
- 2005-06-22 TW TW094120880A patent/TWI396532B/zh not_active IP Right Cessation
-
2006
- 2006-12-06 IL IL179872A patent/IL179872A/en not_active IP Right Cessation
-
2007
- 2007-01-19 LV LVP-07-05A patent/LV13564B/lv unknown
- 2007-01-22 NO NO20070408A patent/NO20070408L/no not_active Application Discontinuation
-
2008
- 2008-11-12 CY CY20081101287T patent/CY1110435T1/el unknown
-
2010
- 2010-04-21 US US12/764,764 patent/US8410168B2/en not_active Expired - Fee Related
-
2011
- 2011-05-27 US US13/118,330 patent/US20110294891A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI1768657T1 (sl) | Postopki in sestavki za zdravljenje oftalmičnih obolenj z derivati retinila | |
| TWI369996B (en) | Ophthalmic compositions and methods for treating eyes | |
| ZA200700918B (en) | Compositions and methods for treating eye disorders and conditions | |
| PT2374472T (pt) | Composições e métodos para o tratamento de afeções oftalmológicas | |
| EP1742641A4 (en) | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF RETINA DISEASES | |
| IL186895A0 (en) | Methods for treating eye conditions | |
| EP1715799A4 (en) | METHOD FOR TREATING GLAUCOMA | |
| PT1755391E (pt) | Métodos e composições para o tratamento de neuropatias | |
| EP1737482A4 (en) | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES | |
| IL182837A0 (en) | Methods, assays and compositions for treating retinol-related diseases | |
| IL183535A0 (en) | Rubber formulation and methods for manufacturing same | |
| ZA200703827B (en) | New pyridothlenopyrimidine derivates | |
| GB0613730D0 (en) | Methods and compositions for treating opthalmic conditions via serum retinol modulation | |
| EP1877840A4 (en) | OPHTHALMIC APPARATUS AND METHODS | |
| ZA200700596B (en) | Methods and compositions for treating ophthalmic conditions with retinyl derivatives | |
| PL2374472T3 (pl) | Kompozycje i sposoby leczenia zaburzeń okulistycznych | |
| ZA200704428B (en) | Rubber formulation and methods for manufacturing same | |
| AU2012258341A1 (en) | Methods and compositions for treating conditions | |
| HK1103984A (en) | Compositions and methods for treating eye disorders and conditions | |
| HK1096031A (en) | Compositions and methods for treating contracture | |
| GB0505077D0 (en) | Ophthalmic apparatus and method | |
| GB0401399D0 (en) | Ophthalmic device | |
| HK1107578A (en) | Compositions and methods for treating hyperproliferative disorders | |
| AU158396S (en) | Sunglasses | |
| PL376747A1 (pl) | Nowe kopolimery organiczno-nieorganiczne oraz sposób ich wytwarzania |