PL1811959T3 - Zastosowanie substancji chemicznych w zespole suchego oka - Google Patents

Zastosowanie substancji chemicznych w zespole suchego oka

Info

Publication number
PL1811959T3
PL1811959T3 PL05821259T PL05821259T PL1811959T3 PL 1811959 T3 PL1811959 T3 PL 1811959T3 PL 05821259 T PL05821259 T PL 05821259T PL 05821259 T PL05821259 T PL 05821259T PL 1811959 T3 PL1811959 T3 PL 1811959T3
Authority
PL
Poland
Prior art keywords
methods
ophthalmic compositions
treating eyes
eyes
treating
Prior art date
Application number
PL05821259T
Other languages
English (en)
Inventor
Joseph G Vehige
Peter A Simmons
Joan-En Chang-Lin
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36218032&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1811959(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of PL1811959T3 publication Critical patent/PL1811959T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1732—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL05821259T 2004-11-16 2005-11-14 Zastosowanie substancji chemicznych w zespole suchego oka PL1811959T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/990,811 US8569367B2 (en) 2004-11-16 2004-11-16 Ophthalmic compositions and methods for treating eyes
PCT/US2005/041064 WO2006055454A2 (en) 2004-11-16 2005-11-14 Ophthalmic compositions and methods for treating eyes
EP05821259.8A EP1811959B2 (en) 2004-11-16 2005-11-14 Ophthalmic compositions

Publications (1)

Publication Number Publication Date
PL1811959T3 true PL1811959T3 (pl) 2015-11-30

Family

ID=36218032

Family Applications (3)

Application Number Title Priority Date Filing Date
PL10185764T PL2422765T3 (pl) 2004-11-16 2005-11-14 Mieszaniny okulistyczne i sposoby leczenia oczu
PL05821259T PL1811959T3 (pl) 2004-11-16 2005-11-14 Zastosowanie substancji chemicznych w zespole suchego oka
PL383268A PL218364B1 (pl) 2004-11-16 2005-11-14 Miejscowa kompozycja oftalmiczna do leczenia suchego oka

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL10185764T PL2422765T3 (pl) 2004-11-16 2005-11-14 Mieszaniny okulistyczne i sposoby leczenia oczu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL383268A PL218364B1 (pl) 2004-11-16 2005-11-14 Miejscowa kompozycja oftalmiczna do leczenia suchego oka

Country Status (23)

Country Link
US (11) US8569367B2 (pl)
EP (4) EP3777836A1 (pl)
JP (1) JP5179880B2 (pl)
KR (1) KR101344602B1 (pl)
CN (1) CN101056618B (pl)
AR (1) AR052031A1 (pl)
AU (2) AU2005306721B2 (pl)
BR (2) BR122019023144B8 (pl)
CA (1) CA2588044C (pl)
CY (2) CY1116545T1 (pl)
DK (3) DK2952178T3 (pl)
ES (3) ES2543974T3 (pl)
HU (2) HUE026575T2 (pl)
IL (1) IL182532A (pl)
NO (3) NO346214B1 (pl)
NZ (2) NZ597106A (pl)
PL (3) PL2422765T3 (pl)
PT (2) PT2422765E (pl)
RU (1) RU2410081C2 (pl)
SI (2) SI2422765T1 (pl)
TW (1) TWI369996B (pl)
WO (1) WO2006055454A2 (pl)
ZA (1) ZA200702917B (pl)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050147584A1 (en) * 2004-01-05 2005-07-07 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
US7220422B2 (en) 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
TWI393567B (zh) * 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
WO2007005421A2 (en) * 2005-07-01 2007-01-11 Bausch & Lomb Incorporated Long lasting alginate dry eye, related methods of manufacture and methods of use
CA2611909C (en) * 2005-07-01 2014-01-07 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition for treatment of corneal disease
CN1939534B (zh) * 2005-09-27 2010-12-01 长春金赛药业股份有限公司 含有人生长激素或人粒细胞巨噬细胞刺激因子的用于治疗损伤和溃疡的外用制剂
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US8138156B2 (en) 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
MX2009005503A (es) * 2006-12-11 2009-06-04 Sigma Tau Ind Farmaceuti Uso de l-carnitina para la preparacion de un medicamento en forma de gotas oculares para el tratamiento de enfermedades de la cornea.
DE102006060953A1 (de) * 2006-12-12 2008-08-07 Farco-Pharma Gmbh Pharmazeutische Zubereitung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes
WO2008071528A1 (en) * 2006-12-14 2008-06-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye drops
US20080148689A1 (en) * 2006-12-20 2008-06-26 Bausch & Lomb Incorporated Packaging solutions
US8629099B2 (en) 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
EP2349232A1 (en) * 2008-10-20 2011-08-03 Allergan, Inc. Ophthalmic compositions useful for improving visual acuity
US8496976B2 (en) 2009-06-05 2013-07-30 Allergan, Inc. Artificial tears and therapeutic uses
ITMI20100319A1 (it) * 2010-02-26 2011-08-27 Lo Li Pharma Srl Composizioni comprendenti mioinositolo e il loro uso nel trattamento delle malattie respiratorie.
US9636355B2 (en) * 2011-09-22 2017-05-02 Theo Holdings, Llc Hypertonic dextran solution and methods of treating and preventing recurrent corneal erosion
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
CA2858574C (en) 2011-12-07 2017-05-30 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
KR102291754B1 (ko) * 2011-12-23 2021-08-20 웨스턴 시드니 유니버시티 안과용 제형물
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US10085960B2 (en) 2012-03-30 2018-10-02 Brien Holden Vision Institute Methods and compositions for reducing ocular discomfort
RU2687275C2 (ru) * 2013-02-01 2019-05-13 Аллерган, Инк. Слезозаменитель, содержащий гиалуронат натрия и карбоксиметилцеллюлозу
ES2781114T3 (es) 2014-08-20 2020-08-28 Silk Tech Ltd Composición proteica derivada de fibroína
NZ732058A (en) 2014-11-25 2023-06-30 Allergan Inc Stabilized omega-3 ophthalmic compositions
ITUB20153104A1 (it) * 2015-08-13 2017-02-13 Sooft Italia S P A Contrada Molino 17 68333 Montegiorgio Fm Composizione ed uso di collirio a base di inositolo per migliorare l'accomodazione visiva dei pazienti
US10940042B2 (en) 2015-10-23 2021-03-09 The Trustees Of Columbia University In The City Of New York Laser induced collagen crosslinking in tissue
KR20190008210A (ko) 2016-04-08 2019-01-23 코넬 유니버시티 실크 유래 단백질을 이용한 상처 치료를 증가시키는 방법
US11497403B2 (en) 2016-06-10 2022-11-15 The Trustees Of Columbia University In The City Of New York Devices, methods, and systems for detection of collagen tissue features
RU2623205C1 (ru) * 2016-07-13 2017-06-22 Станислав Анатольевич Кедик Офтальмологический гель таурина
MX2019001633A (es) 2016-08-12 2019-09-18 Silk Tech Ltd Proteina derivada de la seda para el tratamiento de la inflamacion.
US11666481B1 (en) 2017-12-01 2023-06-06 The Trustees Of Columbia University In The City Of New York Diagnosis and treatment of collagen-containing tissues
SG10201907137RA (en) * 2019-08-02 2021-03-30 Singapore Health Serv Pte Ltd Use of an osmolyte in manufacture of a medicament for treatment of ocular disorders
EP4057941A4 (en) 2019-11-15 2024-05-29 Silk Technologies Ltd. Stable formulations of silk-derived protein
CN111467349B (zh) * 2020-05-14 2021-06-01 华熙生物科技股份有限公司 人工泪液及其制备方法
CN116940662A (zh) 2021-03-10 2023-10-24 博士伦爱尔兰有限公司 不含防腐剂的隐形眼镜处理溶液
US12012238B2 (en) * 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
WO2023034993A1 (en) * 2021-09-03 2023-03-09 Gleich Gerald J Compositions and methods for diagnosing, detecting and treating eosinophil-related diseases
IT202300019488A1 (it) * 2023-09-21 2025-03-21 D&V Farma Soc A Responsabilita Limitata Composizioni, usi e metodi per il trattamento della sindrome dell’occhio secco o per promuovere la guarigione delle ferite corneali
WO2025175150A1 (en) * 2024-02-16 2025-08-21 Allergan, Inc. Enhanced artificial tear formulations

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1781701A (en) 1928-05-16 1930-11-18 Phillips Morris Godfrey Philip Machine for removing flags and other adhering leaf from the stalks of tobacco leaves
US3278447A (en) 1963-12-02 1966-10-11 Cloro Bac Products Inc Process for stabilizing chlorine dioxide solution
US4201706A (en) 1978-09-22 1980-05-06 Burton, Parsons & Company, Inc. Treatment of corneal edema
ATE6466T1 (de) 1979-10-26 1984-03-15 Smith And Nephew Associated Companies P.L.C. Autoklavierbare emulsionen.
EP0145710A1 (en) * 1983-05-25 1985-06-26 Alcon Laboratories, Inc. Ophthalmic solution
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
JPS6436255A (en) * 1987-07-31 1989-02-07 Fujitsu Ltd Feeding circuit
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
IT1235153B (it) * 1988-11-15 1992-06-22 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento
IT1224795B (it) 1988-12-01 1990-10-24 Sigma Tau Ind Farmaceuti Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento
US5221696A (en) * 1989-03-29 1993-06-22 Alcon Laboratories, Inc. Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs
DE436726T1 (de) 1989-08-03 1992-02-06 Eisai Co., Ltd., Tokio/Tokyo Verfahren zur photostabilisierung von augenspuelloesungen sowie photostabilisierte augenspuelloesung.
US5681555A (en) 1991-04-22 1997-10-28 Gleich; Gerald J. Method for the treatment of bronchial asthma by parenteral administration of anionic polymers
DE4229494A1 (de) * 1992-09-04 1994-03-10 Basotherm Gmbh Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks
JP3431216B2 (ja) 1993-06-18 2003-07-28 千代田化工建設株式会社 触媒層支持構造
EP0778021A4 (en) 1994-09-14 1998-06-03 Taisho Pharmaceutical Co Ltd DROPS TO CARE FOR THE CORNEA
US5980865A (en) 1995-08-18 1999-11-09 Baker Norton Pharmaceuticals, Inc. Method for treating late phase allergic reactions and inflammatory diseases
US5847294A (en) * 1996-04-09 1998-12-08 Amherst Process Instruments, Inc. Apparatus for determining powder flowability
JPH1036255A (ja) 1996-07-24 1998-02-10 Nikken Chem Co Ltd 眼圧降下用点眼剤
IT1288399B1 (it) 1996-12-03 1998-09-22 Sigma Tau Ind Farmaceuti Medicamento per il trattamento terapeutico della maculopatia legata all'eta', della maculopatia non legata all'eta' e per la profilassi
FI106923B (fi) 1997-01-03 2001-05-15 Cultor Ltd Finnsugar Bioproduc Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa
AR002194A1 (es) 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6770675B2 (en) * 1997-03-17 2004-08-03 Novartis Ag Compositions and methods for reducing ocular hypertension
IL135258A0 (en) * 1997-09-26 2001-05-20 Noven Pharma Bioadhesive compositions and methods for topical administration of active agents
US6274725B1 (en) 1998-06-02 2001-08-14 Isis Pharmaceuticals, Inc. Activators for oligonucleotide synthesis
IT1302307B1 (it) * 1998-09-01 2000-09-05 Sigma Tau Healthscience Spa Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
RU2211027C2 (ru) * 1998-10-23 2003-08-27 Идеа Аг Способ конструирования, проверки и применения ассоциатов макромолекул и комплексных агрегатов с повышенной полезной нагрузкой и контролируемой степенью ассоциации/диссоциации
AU1295200A (en) * 1998-11-13 2000-06-05 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
US6228392B1 (en) * 1999-04-29 2001-05-08 Gene Tools, Llc Osmotic delivery composition, solution, and method
KR100354606B1 (ko) 2000-02-01 2002-09-30 주식회사 중외제약 다목적 콘택트 렌즈 관리 용액 조성물
CA2416169C (en) * 2000-07-14 2008-09-23 Allergan, Inc. Compositions containing therapeutically active components having enhanced solubility
CA2355814C (en) 2000-09-14 2010-06-29 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pharmaceutical composition for ophthalmic use
US8557868B2 (en) 2000-11-04 2013-10-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions using low molecular weight amines
WO2002038161A1 (en) 2000-11-08 2002-05-16 Bio-Concept Laboratories Improved ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
US20030069410A1 (en) 2001-06-14 2003-04-10 Isis Pharmaceuticals, Inc. Methods for preparing oligonucleotides having chiral phosphorothioate linkages
AR036122A1 (es) 2001-07-03 2004-08-11 Avecia Biotechnology Inc Un complejo de sal que comprende un n-alquilimidazol y una 1,1-dioxo-1,2-dihidro-1l6-benzo [d]-isotiazol-3-ona y un metodo para sintetizar oligonucleotidos utilizando la quimica de fosforamidita
US6936589B2 (en) 2001-09-28 2005-08-30 Albert T. Naito Parenteral delivery systems
US7045121B2 (en) * 2001-12-14 2006-05-16 Allergan, Inc. Ophthalmic compositions for lubricating eyes and methods for making and using same
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
RU2216346C1 (ru) * 2002-06-10 2003-11-20 Семенова Наталья Викторовна Средство и способ для биогенной стимуляции организма
WO2004006801A2 (en) 2002-07-17 2004-01-22 Biosyntrx, Inc. Treatment for dry eye syndrome
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
ITRM20020492A1 (it) 2002-10-01 2004-04-02 Sigma Tau Ind Farmaceuti Uso della propionil l-carnitina per la preparazione di un medicamento per il trattamento del glaucoma.
US20040137079A1 (en) 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
JPWO2004084877A1 (ja) * 2003-03-26 2006-06-29 株式会社メニコン 眼科用組成物
US20050009836A1 (en) 2003-06-26 2005-01-13 Laskar Paul A. Ophthalmic composition containing quinolones and method of use
US8569367B2 (en) * 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
CN101668511A (zh) 2007-02-28 2010-03-10 阿西克斯医疗公司 正常化睑板腺分泌的方法和化合物
JP4929245B2 (ja) 2008-07-31 2012-05-09 株式会社ベッセル工業 工具類のグリップ
US8496976B2 (en) 2009-06-05 2013-07-30 Allergan, Inc. Artificial tears and therapeutic uses
US9907826B2 (en) * 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system

Also Published As

Publication number Publication date
CA2588044A1 (en) 2006-05-26
US8569367B2 (en) 2013-10-29
SI2422765T1 (sl) 2015-09-30
US20140045939A1 (en) 2014-02-13
US20130190398A1 (en) 2013-07-25
US20140256675A1 (en) 2014-09-11
PL218364B1 (pl) 2014-11-28
CY1116936T1 (el) 2017-04-05
US9254324B2 (en) 2016-02-09
US9668997B2 (en) 2017-06-06
BRPI0518173B1 (pt) 2020-05-19
US20250186385A1 (en) 2025-06-12
AU2005306721B2 (en) 2012-03-08
RU2007117637A (ru) 2008-12-27
KR20070084264A (ko) 2007-08-24
US20210401789A1 (en) 2021-12-30
PT1811959E (pt) 2015-11-10
BR122019023144B8 (pt) 2021-07-27
NZ583757A (en) 2011-11-25
AR052031A1 (es) 2007-02-28
EP2952178B1 (en) 2020-09-02
DK1811959T3 (en) 2015-11-23
CN101056618B (zh) 2015-02-11
EP1811959B1 (en) 2015-09-02
PL2422765T3 (pl) 2015-10-30
AU2005306721A1 (en) 2006-05-26
US20060106104A1 (en) 2006-05-18
JP2008520671A (ja) 2008-06-19
US20140045773A1 (en) 2014-02-13
EP1811959A2 (en) 2007-08-01
EP2952178A1 (en) 2015-12-09
BRPI0518173A (pt) 2008-11-04
US8569370B2 (en) 2013-10-29
ES2842226T3 (es) 2021-07-13
ES2550616T3 (es) 2015-11-11
TW200631605A (en) 2006-09-16
NO20240132A1 (no) 2007-08-15
KR101344602B1 (ko) 2013-12-31
NZ597106A (en) 2013-06-28
PL383268A1 (pl) 2008-02-18
DK2422765T3 (en) 2015-08-03
JP5179880B2 (ja) 2013-04-10
US20190365692A1 (en) 2019-12-05
WO2006055454A2 (en) 2006-05-26
HK1107027A1 (zh) 2008-03-28
NO346214B1 (no) 2022-04-25
CN101056618A (zh) 2007-10-17
CA2588044C (en) 2014-05-27
US20160256424A1 (en) 2016-09-08
US10213405B2 (en) 2019-02-26
EP1811959B2 (en) 2022-06-15
HK1218620A1 (en) 2017-03-03
EP2422765B1 (en) 2015-04-29
EP3777836A1 (en) 2021-02-17
SI1811959T2 (sl) 2022-10-28
HUE026575T2 (en) 2016-06-28
BRPI0518173B8 (pt) 2021-05-25
AU2012203398B2 (en) 2015-01-15
NO347855B1 (no) 2024-04-22
US8729125B2 (en) 2014-05-20
DK1811959T4 (da) 2022-06-27
US20180021282A1 (en) 2018-01-25
EP2422765A1 (en) 2012-02-29
IL182532A (en) 2013-10-31
TWI369996B (en) 2012-08-11
DK2952178T3 (da) 2020-12-07
SI1811959T1 (sl) 2015-11-30
BRPI0518173A8 (pt) 2018-01-23
RU2410081C2 (ru) 2011-01-27
ES2550616T5 (es) 2022-09-29
BR122019023144B1 (pt) 2021-02-09
NO20220060A1 (pl) 2007-08-15
AU2012203398A1 (en) 2012-06-28
IL182532A0 (en) 2007-09-20
ES2543974T3 (es) 2015-08-26
US20230404961A1 (en) 2023-12-21
HUE025116T2 (en) 2016-01-28
CY1116545T1 (el) 2017-03-15
WO2006055454A3 (en) 2006-08-03
NO20072170L (no) 2007-08-15
PT2422765E (pt) 2015-09-16
ZA200702917B (en) 2008-09-25

Similar Documents

Publication Publication Date Title
TWI369996B (en) Ophthalmic compositions and methods for treating eyes
ZA200700918B (en) Compositions and methods for treating eye disorders and conditions
PT2374472T (pt) Composições e métodos para o tratamento de afeções oftalmológicas
SI1881823T1 (sl) Sestavki in postopki za zdravljenje bolezni oäśesa
EP1737482A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES
EP1742641A4 (en) METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF RETINA DISEASES
IL179872A0 (en) Methods and compositions for treating ophthalmic conditions with retinyl derivatives
ZA200610492B (en) Ocular implant and methods for making and using same
GB2423928B (en) Methods and compositions for treating pain
PT3006040T (pt) Métodos e composições para o tratamento de neuropatias
EP1893216A4 (en) METHOD AND COMPOSITIONS FOR THE TREATMENT OF EYE DISEASES
EP1715799A4 (en) METHOD FOR TREATING GLAUCOMA
IL184047A0 (en) Methods and compositions for treating amyloid-related diseases
IL183506A0 (en) Compositions and methods for treating neoplastic diseases
EP2083862A4 (en) COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES AND DISORDERS
ZA200705297B (en) Methods and compositions for treating amyloid related diseases
WO2006121421A8 (en) Methods and formulations for treating glaucoma
SI1884234T1 (sl) Profilaktično ali terapevtsko sredstvo za kornealno in konjunktivalno motnjo
EP1877840A4 (en) OPHTHALMIC APPARATUS AND METHODS
PL2374472T3 (pl) Kompozycje i sposoby leczenia zaburzeń okulistycznych
ZA200700596B (en) Methods and compositions for treating ophthalmic conditions with retinyl derivatives
EP1674091A4 (en) OPHTHALMIC COMPOSITION FOR THE TREATMENT OF LACRYMAL DISORDERS
HK1103984A (en) Compositions and methods for treating eye disorders and conditions
ZA200704093B (en) Methods and fluorinated compositions for treating amyloid-related diseases
HK1113566A (en) Methods and compositions for treating amyloid-related diseases