PL1828239T3 - Produkcja FGF18 w organizmach prokariotycznych - Google Patents

Produkcja FGF18 w organizmach prokariotycznych

Info

Publication number: PL1828239T3
Authority: PL; Poland
Prior art keywords: fgf18; coli; production; expression; ompt
Prior art date: 2004-12-10

Application number

PL05853969T

Other languages

English (en)

Inventor

Brian J Reardon

Susan D Julien

Chung-Leung Chan

Hong Y Liu

Original Assignee

Zymogenetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-10

Filing date

2005-12-12

Publication date

2012-01-31

2005-12-12 Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc

2012-01-31 Publication of PL1828239T3 publication Critical patent/PL1828239T3/pl

Links

101150106178 FGF18 gene Proteins 0.000 title abstract 2
102000003977 fibroblast growth factor 18 Human genes 0.000 title 1
241000588724 Escherichia coli Species 0.000 abstract 4
102100035323 Fibroblast growth factor 18 Human genes 0.000 abstract 3
101000878128 Homo sapiens Fibroblast growth factor 18 Proteins 0.000 abstract 3
239000013604 expression vector Substances 0.000 abstract 3
108091026890 Coding region Proteins 0.000 abstract 1
108020004705 Codon Proteins 0.000 abstract 1
101100390711 Escherichia coli (strain K12) fhuA gene Proteins 0.000 abstract 1
230000002950 deficient Effects 0.000 abstract 1
238000000855 fermentation Methods 0.000 abstract 1
230000004151 fermentation Effects 0.000 abstract 1
238000011031 large-scale manufacturing process Methods 0.000 abstract 1
108020004999 messenger RNA Proteins 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

PL05853969T 2004-12-10 2005-12-12 Produkcja FGF18 w organizmach prokariotycznych PL1828239T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US63502304P	2004-12-10	2004-12-10
EP05853969A EP1828239B1 (en)	2004-12-10	2005-12-12	Fgf18 production in prokaryotic hosts
PCT/US2005/045166 WO2006063362A1 (en)	2004-12-10	2005-12-12	Fgf18 production in prokaryotic hosts

Publications (1)

Publication Number	Publication Date
PL1828239T3 true PL1828239T3 (pl)	2012-01-31

Family

ID=36061577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL05853969T PL1828239T3 (pl)	2004-12-10	2005-12-12	Produkcja FGF18 w organizmach prokariotycznych

Country Status (12)

Country	Link
US (1)	US7858341B2 (pl)
EP (1)	EP1828239B1 (pl)
AT (1)	ATE521633T1 (pl)
AU (1)	AU2005314438B2 (pl)
CA (1)	CA2592261C (pl)
CY (1)	CY1112394T1 (pl)
DK (1)	DK1828239T3 (pl)
ES (1)	ES2371219T3 (pl)
PL (1)	PL1828239T3 (pl)
PT (1)	PT1828239E (pl)
SI (1)	SI1828239T1 (pl)
WO (1)	WO2006063362A1 (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1931704T3 (da) *	2005-10-04	2011-03-14	Zymogenetics L L C	Frembringelse og rensning af IL-29
KR101419961B1 (ko) *	2006-08-25	2014-07-30	아레스 트레이딩 에스.에이.	Ｆｇｆ-18 로 연골 질환의 치료
MY148277A (en) *	2006-08-25	2013-03-29	Ares Trading Sa	Treatment of cartilage disorders with fgf-18
KR101741859B1 (ko)	2009-06-22	2017-06-15	암젠 인크	화학적으로 조절된 산화환원 상태를 사용한 단백질의 재폴딩
SI3660032T1 (sl)	2009-06-25	2026-02-27	Amgen Inc.	Postopki zajemanja in čiščenja beljakovin, izraženih v nesesalskem sistemu
WO2012038953A2 (en)	2010-09-21	2012-03-29	Hepacore Ltd.	Fgf-18 truncated variants having increased receptor specificity and uses thereof
WO2012140650A2 (en)	2011-04-12	2012-10-18	Hepacore Ltd.	Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
TW201307563A (zh) *	2011-05-19	2013-02-16	Shire Human Genetic Therapies	純化乙醯肝素－ｎ－硫酸酯酶之方法
TWI527590B (zh)	2011-06-17	2016-04-01	艾瑞斯貿易公司	Ｆｇｆ－１８之凍乾調配物
WO2013130001A1 (en) *	2012-02-29	2013-09-06	Ge Healthcare Bio-Sciences Ab	Method for endotoxin removal
US10041050B2 (en)	2012-02-29	2018-08-07	Ge Healthcare Bioprocess R&D Ab	Method for endotoxin removal
CA2881024C (en)	2012-08-06	2021-06-15	Christoph Hubertus LADEL	Genetic markers for predicting responsiveness to fgf-18 compound
HRP20181573T1 (hr) *	2014-02-20	2018-11-30	Merck Patent Gmbh	Implantat koji sadrži fgf-18
KR101608734B1 (ko)	2014-03-21	2016-04-04	씨제이제일제당 주식회사	L-아미노산을 생산하는 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법
CA2971315C (en)	2015-01-29	2023-02-14	Ares Trading S.A.	Immunoassays for high positively charged proteins
CN107849151B (zh) *	2015-07-15	2022-05-24	德益阳光生物技术（北京）有限责任公司	融合多肽及使用方法
DK3688468T3 (da)	2017-09-29	2022-06-20	Merck Patent Gmbh	Inflammatoriske biomarkører til forudsigelse af modtageligheden for fgf-18 forbindelse
DK3687558T3 (da)	2017-09-29	2022-06-20	Merck Patent Gmbh	Metaboliske biomarkører til forudsigelse af modtageligheden på fgf-18 forbindelse
IL281333B2 (en)	2018-09-10	2025-11-01	Merck Patent Gmbh	A method for reducing risk in a clinical trial
CN110759986B (zh) *	2019-10-18	2023-01-31	大连工业大学	一种可逆自组装蛋白的高效制备方法
CN114181321B (zh) *	2021-12-10	2023-04-11	中国海洋大学	花鲈fgf6a、fgf6b以及fgf18重组蛋白及其制备方法和应用
JPWO2024084807A1 (pl) *	2022-10-19	2024-04-25

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5604293A (en)	1985-09-12	1997-02-18	Scios Inc.	Recombinant human basic fibroblast growth factor
US5439818A (en)	1985-09-12	1995-08-08	Scios Nova Inc.	DNA encoding human recombinant basic fibroblast growth factor
US5773252A (en)	1995-06-05	1998-06-30	Human Genome Sciences, Inc.	Fibroblast growth factor 15
US7135459B2 (en)	1996-10-16	2006-11-14	Zymogenetics, Inc.	Methods of use of FGF homologs
US20050043234A1 (en)	1996-10-16	2005-02-24	Deisher Theresa A.	Novel FGF homologs
ATE491029T1 (de) *	1996-10-16	2010-12-15	Zymogenetics Inc	Fibroblasten-wachstumsfaktoren-homologe
US6518236B1 (en)	1996-10-16	2003-02-11	Zymogenetics, Inc.	FGF homologs
EP1234033B1 (en) *	1999-12-02	2011-12-28	ZymoGenetics, Inc.	Methods for targeting cells that express fibroblast growth factor receptor-3 or-2
US20040136970A1 (en)	2002-10-07	2004-07-15	Ellsworth Jeff L.	Methods for administering FGF18
US20040229292A1 (en)	2002-11-26	2004-11-18	Sebastiano Cavallaro	Use of FGF-18 in the diagnosis and treatment of memory disorders

2005
- 2005-12-12 SI SI200531396T patent/SI1828239T1/sl unknown
- 2005-12-12 WO PCT/US2005/045166 patent/WO2006063362A1/en not_active Ceased
- 2005-12-12 DK DK05853969.3T patent/DK1828239T3/da active
- 2005-12-12 PL PL05853969T patent/PL1828239T3/pl unknown
- 2005-12-12 CA CA2592261A patent/CA2592261C/en not_active Expired - Lifetime
- 2005-12-12 ES ES05853969T patent/ES2371219T3/es not_active Expired - Lifetime
- 2005-12-12 AU AU2005314438A patent/AU2005314438B2/en not_active Expired
- 2005-12-12 EP EP05853969A patent/EP1828239B1/en not_active Expired - Lifetime
- 2005-12-12 PT PT05853969T patent/PT1828239E/pt unknown
- 2005-12-12 AT AT05853969T patent/ATE521633T1/de active
- 2005-12-12 US US11/301,383 patent/US7858341B2/en not_active Expired - Lifetime
2011
- 2011-11-24 CY CY20111101149T patent/CY1112394T1/el unknown

Also Published As

Publication number	Publication date
ES2371219T3 (es)	2011-12-28
WO2006063362A1 (en)	2006-06-15
CA2592261A1 (en)	2006-06-15
US20060172384A1 (en)	2006-08-03
SI1828239T1 (sl)	2011-11-30
AU2005314438B2 (en)	2012-03-29
ATE521633T1 (de)	2011-09-15
AU2005314438A1 (en)	2006-06-15
US7858341B2 (en)	2010-12-28
EP1828239A1 (en)	2007-09-05
CA2592261C (en)	2015-11-24
HK1113161A1 (en)	2008-09-26
DK1828239T3 (da)	2011-12-19
CY1112394T1 (el)	2015-12-09
EP1828239B1 (en)	2011-08-24
PT1828239E (pt)	2011-10-27

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