PL1831242T3 - Zmniejszanie zawartości zanieczyszczeń białkowych w kompozycjach zawierających zależne od witaminy K białko będące przedmiotem zainteresowania - Google Patents
Zmniejszanie zawartości zanieczyszczeń białkowych w kompozycjach zawierających zależne od witaminy K białko będące przedmiotem zainteresowaniaInfo
- Publication number
- PL1831242T3 PL1831242T3 PL05850495T PL05850495T PL1831242T3 PL 1831242 T3 PL1831242 T3 PL 1831242T3 PL 05850495 T PL05850495 T PL 05850495T PL 05850495 T PL05850495 T PL 05850495T PL 1831242 T3 PL1831242 T3 PL 1831242T3
- Authority
- PL
- Poland
- Prior art keywords
- protein
- vitamin
- interest
- compositions
- reduction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200402008 | 2004-12-23 | ||
| EP05850495A EP1831242B1 (en) | 2004-12-23 | 2005-12-23 | Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest |
| PCT/EP2005/057145 WO2006067230A1 (en) | 2004-12-23 | 2005-12-23 | Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1831242T3 true PL1831242T3 (pl) | 2013-04-30 |
Family
ID=36168465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05850495T PL1831242T3 (pl) | 2004-12-23 | 2005-12-23 | Zmniejszanie zawartości zanieczyszczeń białkowych w kompozycjach zawierających zależne od witaminy K białko będące przedmiotem zainteresowania |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9187549B2 (pl) |
| EP (2) | EP1831242B1 (pl) |
| JP (2) | JP2008525381A (pl) |
| KR (2) | KR101364001B1 (pl) |
| CN (1) | CN101098883B (pl) |
| AU (1) | AU2005318106B2 (pl) |
| BR (1) | BRPI0519626A2 (pl) |
| CA (1) | CA2592054A1 (pl) |
| ES (1) | ES2395544T3 (pl) |
| MX (1) | MX2007007356A (pl) |
| PL (1) | PL1831242T3 (pl) |
| RU (1) | RU2460735C2 (pl) |
| WO (1) | WO2006067230A1 (pl) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1831242B1 (en) | 2004-12-23 | 2012-09-26 | Novo Nordisk Health Care AG | Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest |
| JP5147692B2 (ja) | 2005-07-13 | 2013-02-20 | ノボ ノルディスク ヘルス ケア アーゲー | 治療用タンパク質生成のための宿主細胞タンパク質ノックアウト細胞 |
| AT502691A1 (de) * | 2005-10-24 | 2007-05-15 | Univ Fuer Weiterbildung Krems | Extrakorporales blut- oder plasmareinigungssystem |
| US9956272B2 (en) | 2007-05-30 | 2018-05-01 | Bio Products Laboratory Limited | Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same |
| GB0710321D0 (en) * | 2007-05-30 | 2007-07-11 | Nhs Blood & Transplant | Method |
| BRPI0814220B8 (pt) * | 2007-07-11 | 2021-05-25 | Novo Nordisk As | purificação de fator viii usando uma resina multimodal ou de modo misto |
| TWI465247B (zh) | 2008-04-11 | 2014-12-21 | Catalyst Biosciences Inc | 經修飾的因子vii多肽和其用途 |
| JP5788803B2 (ja) * | 2008-12-02 | 2015-10-07 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | ポリペプチド精製 |
| FR2946348B1 (fr) * | 2009-06-05 | 2011-08-05 | Lab Francais Du Fractionnement | Procede de preparation d'une composition de complexe prothrombique a haut degre de purete |
| US8129139B2 (en) | 2009-07-13 | 2012-03-06 | Allergan, Inc. | Process for obtaining botulinum neurotoxin |
| EP4328305A3 (en) | 2009-12-18 | 2024-08-14 | CSL Ltd. | Method of purifying polypeptides |
| US9896677B2 (en) | 2010-01-18 | 2018-02-20 | Novo Nordisk Health Care Ag | Purification of blood coagulation factors |
| CN102858971B (zh) * | 2010-03-30 | 2016-06-01 | 奥克塔法马股份有限公司 | 纯化维生素k依赖性蛋白如凝血因子ix的方法 |
| CN103025757A (zh) * | 2010-04-29 | 2013-04-03 | 巴克斯特国际有限公司 | 二价阳离子结合蛋白在阴离子交换树脂上的纯化方法 |
| EP2652491B1 (en) | 2010-12-15 | 2017-11-29 | Baxalta GmbH | Eluate collection using conductivity gradient |
| CN102161701A (zh) * | 2011-01-28 | 2011-08-24 | 上海兴迪金生物技术有限公司 | 从细胞培养液或血浆组分中分离纯化高纯度活化凝血七因子的方法 |
| JP2011172602A (ja) * | 2011-06-15 | 2011-09-08 | Jcr Pharmaceuticals Co Ltd | 組換え体ヒトfshの製造方法 |
| WO2013053888A1 (en) * | 2011-10-14 | 2013-04-18 | Baxter International Inc. | Protein purification by anion exchange chromatography |
| PL2748179T3 (pl) * | 2011-10-14 | 2022-04-11 | Takeda Pharmaceutical Company Limited | Oczyszczanie białka metodą anionowej chromatografii jonowymiennej |
| TR201808584T4 (tr) | 2013-03-15 | 2018-07-23 | Baxalta GmbH | Anyon değişimi kromotografisi aracılığıyla k vitaminine bağlı proteinler için saflaştırma yöntemi. |
| WO2014181549A1 (ja) | 2013-05-10 | 2014-11-13 | 株式会社デンソー | 燃料噴射制御装置および燃料噴射システム |
| JP5750471B2 (ja) * | 2013-05-22 | 2015-07-22 | Jcrファーマ株式会社 | 組換え体ヒトfshの製造方法 |
| WO2016207328A1 (en) * | 2015-06-24 | 2016-12-29 | Glycotope Gmbh | PROCESS FOR THE PURIFICATION OF γ-CARBOXYLATED POLYPEPTIDES |
| KR102432962B1 (ko) | 2017-03-16 | 2022-08-12 | 쉔첸 인스티튜트스 오브 어드밴스드 테크놀로지 | 에너지 대사를 조절하는 폴리펩티드 및 그 용도 |
| WO2018165933A1 (zh) * | 2017-03-16 | 2018-09-20 | 深圳先进技术研究院 | 调节糖代谢的多肽及其用途 |
| EP3590528A1 (en) * | 2018-07-06 | 2020-01-08 | Octapharma AG | Fx activation process and its use in the preparation of a fxa composition |
| EP3833381B1 (en) | 2019-08-15 | 2022-08-03 | Catalyst Biosciences, Inc. | Modified factor vii polypeptides for subcutaneous administration |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5055557A (en) | 1983-03-04 | 1991-10-08 | Scripps Clinic & Research Foundation | Ultrapurification of factor IX and other vitamin K-dependent proteins |
| DE3485711D1 (de) * | 1983-03-04 | 1992-06-17 | Scripps Clinic Res | Immunoadsorbens und verfahren zur zurueckgewinnung von vitamin-k-abhaengigen proteinen mittels dieses adsorbens. |
| GR860984B (en) | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
| US4721572A (en) | 1985-07-12 | 1988-01-26 | Miles Laboratories, Inc. | Purfication of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices |
| JPH0759600B2 (ja) | 1986-12-15 | 1995-06-28 | 帝人株式会社 | ヒト・プロテインsに対するモノクローナル抗体 |
| JPH01231893A (ja) | 1988-03-14 | 1989-09-18 | Fuji Yakuhin Kogyo Kk | 抗ヒトプロテインsモノクローナル抗体およびその利用 |
| US4981952A (en) | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
| US5077214A (en) | 1989-07-07 | 1991-12-31 | The Texas A&M University System | Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells |
| JP2824430B2 (ja) | 1989-08-02 | 1998-11-11 | 財団法人化学及血清療法研究所 | 血液凝固第▲vii▼因子または活性型血液凝固第▲vii▼因子の調製方法 |
| US5580560A (en) | 1989-11-13 | 1996-12-03 | Novo Nordisk A/S | Modified factor VII/VIIa |
| AT402261B (de) * | 1991-01-25 | 1997-03-25 | Immuno Ag | Komplex enthaltend den gerinnungsfaktor ix |
| DK0658168T3 (da) | 1992-08-27 | 2001-01-22 | Sanquin Bloedvoorziening | Antistoffer, som er specifikke for et hæmostatisk protein, anvendelse heraf til isolering af intakt protein, hæmostatiske p |
| DK38293D0 (da) | 1993-03-31 | 1993-03-31 | Novo Nordisk As | Fremstilling af proteiner |
| DE4342132C1 (de) | 1993-12-10 | 1994-11-03 | Octapharma Ag | Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie |
| DE4406515C1 (de) * | 1994-02-28 | 1995-10-19 | Immuno Ag | Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine |
| GB9519197D0 (en) | 1995-09-20 | 1995-11-22 | Affinity Chromatography Ltd | Novel affinity ligands and their use |
| US6117996A (en) | 1995-09-20 | 2000-09-12 | Novo Nordisk A/S | Triazine based ligands and use thereof |
| JP3745805B2 (ja) * | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | トロンボモジュリンの精製方法 |
| DE19538715A1 (de) | 1995-10-18 | 1997-04-30 | Behringwerke Ag | Verfahren zur Reinigung von Faktor VII und aktiviertem Faktor VII |
| PT1754718E (pt) | 1996-04-24 | 2011-07-13 | Univ Michigan | Factor viii resistente à inactivação |
| US6017882A (en) | 1997-10-23 | 2000-01-25 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6693075B1 (en) | 1997-10-23 | 2004-02-17 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6747003B1 (en) | 1997-10-23 | 2004-06-08 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US7247708B2 (en) | 1997-10-23 | 2007-07-24 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| JP2000143692A (ja) | 1998-11-11 | 2000-05-26 | Fujimori Kogyo Co Ltd | モノクローナル抗体によって精製されたトロンビン基質または阻害剤の精製方法 |
| AU3273200A (en) | 1999-03-15 | 2000-10-04 | Novo Nordisk A/S | Ion exchange chromatographic separation of glp-1 and related peptides |
| AU5805500A (en) | 1999-07-07 | 2001-01-30 | Maxygen Aps | A method for preparing modified polypeptides |
| JP4451514B2 (ja) | 1999-08-24 | 2010-04-14 | 財団法人化学及血清療法研究所 | 血液凝固第vii因子改変体 |
| WO2001058935A2 (en) | 2000-02-11 | 2001-08-16 | Maxygen Aps | FACTOR VII OR VIIa-LIKE MOLECULES |
| SE0000675D0 (sv) | 2000-03-02 | 2000-03-02 | Protease Ab | Monoclonal antibodies |
| JP2001247599A (ja) | 2000-03-07 | 2001-09-11 | Fujimori Kogyo Co Ltd | ポリペプチド、それを用いた血液凝固因子吸着体、該吸着体を用いた血液凝固因子の精製方法、および該ポリペプチドを含有する血栓形成予防剤 |
| US6952212B2 (en) | 2000-03-24 | 2005-10-04 | Telefonaktiebolaget Lm Ericsson (Publ) | Frame decimation for structure from motion |
| WO2001083725A1 (en) | 2000-05-03 | 2001-11-08 | Novo Nordisk A/S | Human coagulation factor vii variants |
| US6423826B1 (en) | 2000-06-30 | 2002-07-23 | Regents Of The University Of Minnesota | High molecular weight derivatives of vitamin K-dependent polypeptides |
| US20030211094A1 (en) | 2001-06-26 | 2003-11-13 | Nelsestuen Gary L. | High molecular weight derivatives of vitamin k-dependent polypeptides |
| EP2226385B1 (en) * | 2000-09-13 | 2013-07-10 | Novo Nordisk Health Care AG | Human Coagulation Factor VII Variants |
| AU2001291653A1 (en) | 2000-10-02 | 2002-04-15 | Novo-Nordisk A/S | Industrial-scale serum-free production of recombinant factor vii in mammalian cells |
| WO2002038162A1 (en) | 2000-11-09 | 2002-05-16 | The Scripps Research Institute | MODIFIED FACTOR VIIa |
| RU2321633C2 (ru) * | 2001-02-16 | 2008-04-10 | Ново Нордиск Хелт Кэр Аг | Способ получения витамин к-зависимых белков |
| ES2432967T3 (es) | 2001-03-22 | 2013-12-05 | Novo Nordisk Health Care Ag | Derivados del Factor VII de coagulación |
| HUP0500060A3 (en) | 2001-09-27 | 2010-01-28 | Novo Nordisk Healthcare Ag | Human coagulation factor vii polypeptides |
| EP1434857B1 (en) | 2001-10-02 | 2007-08-01 | Novo Nordisk Health Care AG | Method for production of recombinant proteins in eukaryote cells |
| US7795210B2 (en) | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US7125843B2 (en) | 2001-10-19 | 2006-10-24 | Neose Technologies, Inc. | Glycoconjugates including more than one peptide |
| US7265084B2 (en) | 2001-10-10 | 2007-09-04 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
| US7265085B2 (en) | 2001-10-10 | 2007-09-04 | Neose Technologies, Inc. | Glycoconjugation methods and proteins/peptides produced by the methods |
| EP2292273A3 (en) | 2001-10-10 | 2011-11-23 | BioGeneriX AG | Remodeling and glycoconjugation of peptides |
| WO2003092588A2 (en) | 2002-04-30 | 2003-11-13 | Merck & Co., Inc. | 4-azasteroid derivatives as androgen receptor modulators |
| DE60334983D1 (de) | 2002-04-30 | 2010-12-30 | Bayer Healthcare Llc | Faktor vii oder faktor viia polypeptidvarianten |
| ATE370968T1 (de) | 2002-09-25 | 2007-09-15 | Novo Nordisk Healthcare Ag | Varianten des menschliche koagulationsfaktors vii |
| JP4472526B2 (ja) | 2002-09-30 | 2010-06-02 | バイエル ヘルスケア エルエルシー | 凝血活性が増加した第VII因子または第VIIa因子変種 |
| EP1831242B1 (en) | 2004-12-23 | 2012-09-26 | Novo Nordisk Health Care AG | Reduction of the content of protein contaminants in compositions comprising a vitamin k-dependent protein of interest |
-
2005
- 2005-12-23 EP EP05850495A patent/EP1831242B1/en not_active Expired - Lifetime
- 2005-12-23 WO PCT/EP2005/057145 patent/WO2006067230A1/en not_active Ceased
- 2005-12-23 US US11/722,644 patent/US9187549B2/en not_active Expired - Fee Related
- 2005-12-23 ES ES05850495T patent/ES2395544T3/es not_active Expired - Lifetime
- 2005-12-23 JP JP2007547543A patent/JP2008525381A/ja not_active Withdrawn
- 2005-12-23 BR BRPI0519626-4A patent/BRPI0519626A2/pt not_active Application Discontinuation
- 2005-12-23 CN CN2005800464861A patent/CN101098883B/zh not_active Expired - Fee Related
- 2005-12-23 PL PL05850495T patent/PL1831242T3/pl unknown
- 2005-12-23 AU AU2005318106A patent/AU2005318106B2/en not_active Ceased
- 2005-12-23 KR KR1020077015934A patent/KR101364001B1/ko not_active Expired - Fee Related
- 2005-12-23 RU RU2007122413/10A patent/RU2460735C2/ru not_active IP Right Cessation
- 2005-12-23 MX MX2007007356A patent/MX2007007356A/es active IP Right Grant
- 2005-12-23 EP EP10181026A patent/EP2360171A1/en not_active Withdrawn
- 2005-12-23 KR KR1020137028328A patent/KR20130128013A/ko not_active Withdrawn
- 2005-12-23 CA CA002592054A patent/CA2592054A1/en not_active Abandoned
-
2012
- 2012-12-19 JP JP2012277078A patent/JP5866274B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101364001B1 (ko) | 2014-02-17 |
| JP2008525381A (ja) | 2008-07-17 |
| CN101098883A (zh) | 2008-01-02 |
| EP2360171A1 (en) | 2011-08-24 |
| WO2006067230A1 (en) | 2006-06-29 |
| JP5866274B2 (ja) | 2016-02-17 |
| ES2395544T3 (es) | 2013-02-13 |
| JP2013100300A (ja) | 2013-05-23 |
| EP1831242B1 (en) | 2012-09-26 |
| CN101098883B (zh) | 2013-01-23 |
| AU2005318106A1 (en) | 2006-06-29 |
| EP1831242A1 (en) | 2007-09-12 |
| RU2007122413A (ru) | 2009-01-27 |
| US20080207880A1 (en) | 2008-08-28 |
| KR20130128013A (ko) | 2013-11-25 |
| US9187549B2 (en) | 2015-11-17 |
| CA2592054A1 (en) | 2006-06-29 |
| KR20070100732A (ko) | 2007-10-11 |
| MX2007007356A (es) | 2007-08-14 |
| RU2460735C2 (ru) | 2012-09-10 |
| AU2005318106B2 (en) | 2011-11-03 |
| BRPI0519626A2 (pt) | 2009-02-25 |
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