PL1891961T3 - Zastosowanie 5'-metylotioadenozyny (mta) w zapobieganiu i/lub leczeniu chorób autoimmunologicznych i/lub odrzucania przeszczepu - Google Patents

Zastosowanie 5'-metylotioadenozyny (mta) w zapobieganiu i/lub leczeniu chorób autoimmunologicznych i/lub odrzucania przeszczepu

Info

Publication number
PL1891961T3
PL1891961T3 PL05728461T PL05728461T PL1891961T3 PL 1891961 T3 PL1891961 T3 PL 1891961T3 PL 05728461 T PL05728461 T PL 05728461T PL 05728461 T PL05728461 T PL 05728461T PL 1891961 T3 PL1891961 T3 PL 1891961T3
Authority
PL
Poland
Prior art keywords
prevention
treatment
methylthioadenosine
mta
autoimmune diseases
Prior art date
Application number
PL05728461T
Other languages
English (en)
Inventor
Diaz Pablo Villoslada
Zaragoza Matías Avila
Bruna Beatriz Moreno
Izquierdo Fernando Corrales
Lasarte Carmen Berasain
Garcia-Trevijano Elena Ruiz
Original Assignee
Proyecto De Biomedicina Cima S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proyecto De Biomedicina Cima S L filed Critical Proyecto De Biomedicina Cima S L
Publication of PL1891961T3 publication Critical patent/PL1891961T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
PL05728461T 2005-03-17 2005-03-17 Zastosowanie 5'-metylotioadenozyny (mta) w zapobieganiu i/lub leczeniu chorób autoimmunologicznych i/lub odrzucania przeszczepu PL1891961T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/ES2005/000139 WO2006097547A1 (es) 2005-03-17 2005-03-17 Empleo de 5'-metiltioadenosina (mta) en la prevención y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes
EP05728461A EP1891961B1 (en) 2005-03-17 2005-03-17 Use of 5'-methylthioadenosine (mta) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection

Publications (1)

Publication Number Publication Date
PL1891961T3 true PL1891961T3 (pl) 2010-02-26

Family

ID=36991307

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05728461T PL1891961T3 (pl) 2005-03-17 2005-03-17 Zastosowanie 5'-metylotioadenozyny (mta) w zapobieganiu i/lub leczeniu chorób autoimmunologicznych i/lub odrzucania przeszczepu

Country Status (19)

Country Link
US (1) US7820637B2 (pl)
EP (1) EP1891961B1 (pl)
JP (1) JP2008533107A (pl)
CN (1) CN101141970A (pl)
AT (1) ATE442854T1 (pl)
AU (1) AU2005329287B2 (pl)
BR (1) BRPI0520129A2 (pl)
CA (1) CA2601557A1 (pl)
CY (1) CY1109539T1 (pl)
DE (1) DE602005016729D1 (pl)
DK (1) DK1891961T3 (pl)
ES (1) ES2334924T3 (pl)
HR (1) HRP20090646T1 (pl)
MX (1) MX2007011327A (pl)
PL (1) PL1891961T3 (pl)
PT (1) PT1891961E (pl)
RS (1) RS51122B (pl)
SI (1) SI1891961T1 (pl)
WO (1) WO2006097547A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2329327B1 (es) * 2008-03-19 2010-09-17 Proyecto De Biomedicina Cima, S.L. Combinaciones sinergicas de 5'-metiltioadenosina.
WO2010142827A1 (es) * 2009-06-11 2010-12-16 Proyecto De Biomedicina Cima, S. L. Propiedades neuroprotectoras de 5'-metiltioadenosina
WO2011054990A2 (es) * 2009-11-05 2011-05-12 Proyecto De Biomedicina Cima, S.L. Composiciones para la inhibición y/o bloqueo de la transición epitelial-mesenquimal
JP5801572B2 (ja) * 2011-03-03 2015-10-28 シーシーアイ株式会社 ＰＰＡＲγ活性化剤
CN105153042B (zh) * 2015-07-17 2017-11-24 四川大学 一种化合物及其在制备治疗可卡因成瘾的药物中的用途
JP2022526604A (ja) 2019-04-05 2022-05-25 プレリュード・セラピューティクス・インコーポレイテッド タンパク質アルギニンメチルトランスフェラーゼ５の選択的阻害剤
WO2020206289A1 (en) * 2019-04-05 2020-10-08 Prelude Therapeutics, Incorporated Selective inhibitors of protein arginine methyltransferase 5
CN114515294A (zh) 2022-02-25 2022-05-20 浙江中医药大学 5’-甲基硫代腺苷在制备肥胖抑制药物或保健品中的应用
CN117122689A (zh) * 2023-09-12 2023-11-28 四川省医学科学院·四川省人民医院 Mta在制备治疗急性葡萄膜炎药物中的应用
CN118141910B (zh) * 2024-04-03 2025-10-28 河北医科大学 甲基转移酶抑制剂作为呼吸道合胞病毒疫苗及过敏疫苗佐剂的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193529B (it) * 1980-04-22 1988-07-08 Bioresearch Srl Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
HUP0001186A3 (en) * 1996-10-16 2002-04-29 Icn Pharmaceuticals Inc Costa Purine l-nucleosides,analogs and pharmaceutical compositions thereof
BR9814820A (pt) * 1997-10-14 2000-10-03 Welfide Corp Compostos de piperazina e seu uso médico
TW466112B (en) 1998-04-14 2001-12-01 Lilly Co Eli Novel use of 2'-deoxy-2',2'-difluorocytidine for immunosuppressive therapy and pharmaceutical composition comprising the same
JP2001072660A (ja) * 1999-09-08 2001-03-21 Welfide Corp ＴＮＦ−α産生抑制剤および／またはＩＬ−１０産生促進剤
PL357555A1 (pl) * 2000-01-31 2004-07-26 Pfizer Products Inc. Pirymidynokarboksyamidy użyteczne jako inhibitoryizoenzymów PDE4
WO2001066518A1 (en) * 2000-03-09 2001-09-13 Ono Pharmaceutical Co., Ltd. φ-SUBSTITUTED PHENYL-PROSTAGLANDIN E-ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
WO2003028712A2 (en) 2001-09-28 2003-04-10 Universite Libre De Bruxelles Purinergic and pyrimidinergic receptor agonists for the treatment of activated cd4+ t lymphocyte-mediated immune diseases
DE10207843A1 (de) * 2002-02-15 2003-09-04 Schering Ag Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen
IL148736A0 (en) * 2002-03-18 2002-09-12 Pharmos Corp Dexanabinol and dexanabinol analogs which regulate inflammation related genes

Also Published As

Publication number Publication date
EP1891961B1 (en) 2009-09-16
ES2334924T3 (es) 2010-03-17
ATE442854T1 (de) 2009-10-15
DE602005016729D1 (de) 2009-10-29
CY1109539T1 (el) 2014-08-13
US20090042831A1 (en) 2009-02-12
CN101141970A (zh) 2008-03-12
US7820637B2 (en) 2010-10-26
CA2601557A1 (en) 2006-09-21
MX2007011327A (es) 2008-01-28
AU2005329287B2 (en) 2011-01-27
PT1891961E (pt) 2009-12-17
BRPI0520129A2 (pt) 2009-04-28
EP1891961A1 (en) 2008-02-27
AU2005329287A1 (en) 2006-09-21
DK1891961T3 (da) 2009-12-21
JP2008533107A (ja) 2008-08-21
RS51122B (sr) 2010-10-31
SI1891961T1 (sl) 2010-01-29
HRP20090646T1 (hr) 2010-01-31
WO2006097547A1 (es) 2006-09-21

Similar Documents

Publication Publication Date Title
CY1109539T1 (el) Χρηση 5'-μεθυλοθειοαδενοσινης (μτα) στην προληψη και/η θεραπεια αυτοανοσων νοσων και/η απορριψης μοσχευματων
HRP20130602T1 (en) 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
ZA200409291B (en) Compositions and methods for coating medical implants
MY144318A (en) Methods of treating hiv infection.
IL195256A0 (en) Compositions of r(+)and s(-)pramipexole and methods of using the same
TW200637522A (en) Skin treatment articles and methods
FR13C0062I1 (pl)
IL216579A0 (en) Aminocyclohexyl ether derivatives and pharmaceutical compositions containing the same
PT1594833E (pt) Derivados do ácido 1-fenilalcanocarboxílico para o tratamento de doenças neurodegenerativas
SG149063A1 (en) Use of modified cyclosporins for the treatment of hcv disorders
WO2004031129A3 (en) Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection
SG150559A1 (en) Antineoplastic combinations of cci-779 and rituximab
PL1855677T3 (pl) 3,11B-Cis-dihydrotetrabenazyny do leczenia schizofrenii i innych psychoz
WO2004087066A3 (en) Hif-1 inhibitors
EP2889034A3 (en) Compositions and methods of treatment comprising ceftaroline
TWI340639B (en) Pharmaceutical composition for treating luts, other than urinary incontinence, associated with oab and/or bph
PL371281A1 (pl) Sposoby i kompozycje do leczenia chorób oczu
WO2006034001A3 (en) Methods of treating hiv infection
WO2004091436A3 (en) Methods and compositions for treating ocular disease
WO2007130509A3 (en) Pyrroloquinoline quinones and use thereof
WO2007059226A3 (en) Photoactivatable antimicrobial agents
PT1590046T (pt) Composição para o tratamento de hiv ou sida
WO2006079121A3 (en) Methods of treating disease with glycosylated interferon
WO2005107871A3 (en) Pyrroloquinoline quinone drugs for treatment of cardiac injury
GB2401044B (en) A composition for use in the treatment or prophylaxis of a skin condition in a subject