PL1907408T3 - Stabilne pochodne NAD/NADH - Google Patents

Stabilne pochodne NAD/NADH

Info

Publication number
PL1907408T3
PL1907408T3 PL06776486T PL06776486T PL1907408T3 PL 1907408 T3 PL1907408 T3 PL 1907408T3 PL 06776486 T PL06776486 T PL 06776486T PL 06776486 T PL06776486 T PL 06776486T PL 1907408 T3 PL1907408 T3 PL 1907408T3
Authority
PL
Poland
Prior art keywords
stable nad
nadh derivatives
nadh
derivatives
nad
Prior art date
Application number
PL06776486T
Other languages
English (en)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1907408T3 publication Critical patent/PL1907408T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL06776486T 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH PL1907408T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
EP06776486.0A EP1907408B1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate
PCT/EP2006/007493 WO2007012494A1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Publications (1)

Publication Number Publication Date
PL1907408T3 true PL1907408T3 (pl) 2014-07-31

Family

ID=37137552

Family Applications (3)

Application Number Title Priority Date Filing Date
PL11167476T PL2364989T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL06776486T PL1907408T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL11167476T PL2364989T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Country Status (16)

Country Link
US (3) US8809013B2 (pl)
EP (3) EP2364989B1 (pl)
JP (2) JP5129133B2 (pl)
KR (4) KR101483829B1 (pl)
CN (2) CN103122371B (pl)
AU (2) AU2006274140B8 (pl)
BR (1) BRPI0614217A2 (pl)
CA (2) CA2737123A1 (pl)
DE (1) DE102005035461A1 (pl)
DK (3) DK2364988T3 (pl)
ES (3) ES2461266T3 (pl)
MX (1) MX2008000946A (pl)
PL (3) PL2364989T3 (pl)
PT (3) PT2364989E (pl)
SG (1) SG187511A1 (pl)
WO (1) WO2007012494A1 (pl)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
JP4786451B2 (ja) * 2005-07-28 2011-10-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Ｎａｄ／ｎａｄｈの安定化
EP2022859A1 (de) * 2007-08-01 2009-02-11 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung
CN101497638B (zh) * 2008-01-30 2012-09-26 中国科学院大连化学物理研究所 一种nad+类似物及其合成和应用
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
CA2750474C (en) * 2009-02-19 2017-07-25 F. Hoffmann-La Roche Ag Fast reaction kinetics of enzymes having low activity in dry chemistry layers
CN102325496B (zh) * 2009-02-19 2015-10-07 霍夫曼-拉罗奇有限公司 分析辅助工具的节省空间的储存
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
CN102471793B (zh) * 2009-07-27 2014-04-30 霍夫曼-拉罗奇有限公司 Carba-nad的酶促合成
WO2011012269A2 (en) 2009-07-27 2011-02-03 Roche Diagnostics Gmbh Method and substances for preparation of n-substituted pyridinium compounds
JP5544423B2 (ja) 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Ｎ置換ピリジニウム化合物の調製のための方法及び物質
EP2287605A1 (de) * 2009-08-20 2011-02-23 Roche Diagnostics GmbH Vereinfachte Magazinierung integrierter Systeme
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
KR101252351B1 (ko) * 2010-05-24 2013-04-08 동국대학교 산학협력단 전기효소적 합성 반응을 위한 ｎａｄ(ｐ) 유도체의 전기화학적 환원 방법
CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
CN103347858B (zh) 2011-01-26 2016-09-14 霍夫曼-拉罗奇有限公司 制备n-取代的吡啶鎓化合物的方法和物质
CN103458786B (zh) 2011-04-12 2015-08-19 霍夫曼-拉罗奇有限公司 分析辅件
US9752990B2 (en) 2013-09-30 2017-09-05 Honeywell International Inc. Low-powered system for driving a fuel control mechanism
CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
EP2760825B1 (de) 2011-09-28 2016-09-14 F.Hoffmann-La Roche Ag Azomediatoren
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
JP6111323B2 (ja) 2012-04-19 2017-04-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 血液中の検体濃度を測定する方法および装置
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
EP2936155B1 (en) 2012-12-20 2018-12-12 Roche Diabetes Care GmbH Method for analyzing a sample of a body fluid
KR101789893B1 (ko) 2012-12-20 2017-11-20 에프. 호프만-라 로슈 아게 의학적 측정 곡선들을 평가하기 위한 방법
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
EP2994536B1 (en) 2013-05-08 2017-06-14 Roche Diabetes Care GmbH Stabilization of enzymes by nicotinic acid
EP3004372A1 (en) 2013-06-04 2016-04-13 Roche Diagnostics GmbH Novel compounds useful for fret and methods related thereto
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
WO2015063025A1 (en) 2013-10-29 2015-05-07 F. Hoffmann-La Roche Ag Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CN106164054B (zh) 2014-04-14 2019-05-07 豪夫迈·罗氏有限公司 吩嗪介导剂
WO2016022604A2 (en) * 2014-08-05 2016-02-11 Becton Dickinson And Company Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples
EP3183246B1 (en) 2014-08-22 2020-09-23 Roche Diagnostics GmbH Redoxindicators
JP6639479B2 (ja) 2014-08-25 2020-02-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 干渉補償型の２電極テストストリップ
WO2017109003A1 (en) 2015-12-21 2017-06-29 F. Hoffmann-La Roche Ag Mutant 3-hydroxybutyrate dehydrogenase from alcaligenes faecalis as well as methods and uses involving the same
WO2017137491A1 (en) 2016-02-09 2017-08-17 Roche Diabetes Care Gmbh Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
JP2019529935A (ja) 2016-10-05 2019-10-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
HUE064713T2 (hu) 2018-02-28 2024-04-28 Hoffmann La Roche Biokompatibilitási bevonat folyamatos analitméréshez
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
CN122182027A (zh) 2020-12-15 2026-06-12 美国雅培糖尿病护理公司 基于nad(p)-依赖酶的传感器的nad(p)储库
WO2025128711A1 (en) 2023-12-12 2025-06-19 Abbott Diabetes Care Inc. Alcohol sensor membrane
WO2025245355A1 (en) 2024-05-24 2025-11-27 Abbott Diabetes Care Inc. Dispensed area and drop solid content tunability

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53107486A (en) * 1977-02-28 1978-09-19 Wako Pure Chem Ind Ltd Stabilized nadh aqueous solution
JPS61274636A (ja) 1985-05-30 1986-12-04 西南自動車工業株式会社 活魚水槽
US5801006A (en) * 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
JP4260245B2 (ja) * 1998-06-25 2009-04-30 株式会社三菱化学ヤトロン 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
WO2001094370A1 (en) 2000-06-07 2001-12-13 Wako Pure Chemical Industries, Ltd. Coenzyme derivatives and enzymes appropriate therefor
ATE345396T1 (de) 2002-05-16 2006-12-15 Hoffmann La Roche Verfahren zur herstellung von polymerschichten
DE10221845A1 (de) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Verfahren und Reagenzsystem mit nicht-regenerierbarem Enzym-Coenzym-Komplex
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate

Also Published As

Publication number Publication date
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
HK1123308A1 (en) 2009-06-12
AU2006274140B8 (en) 2011-02-03
PL2364989T3 (pl) 2014-08-29
AU2006274140B2 (en) 2010-11-11
BRPI0614217A2 (pt) 2011-03-22
AU2006274140A1 (en) 2007-02-01
CN103122371A (zh) 2013-05-29
DK2364989T3 (da) 2014-06-10
DK1907408T3 (da) 2014-06-10
US20140206024A1 (en) 2014-07-24
EP2364988B1 (de) 2014-02-26
ES2461266T3 (es) 2014-05-19
DK2364988T3 (da) 2014-05-26
AU2011200465A1 (en) 2011-02-24
CN103122371B (zh) 2016-12-28
CA2737123A1 (en) 2007-02-01
JP5129133B2 (ja) 2013-01-23
WO2007012494A1 (de) 2007-02-01
JP2009502844A (ja) 2009-01-29
CA2614792C (en) 2011-07-12
KR20110028522A (ko) 2011-03-18
CN101233144B (zh) 2013-02-06
JP2012224638A (ja) 2012-11-15
AU2011200465B2 (en) 2012-02-09
CA2614792A1 (en) 2007-02-01
ES2461624T3 (es) 2014-05-20
KR101483899B1 (ko) 2015-01-16
PT2364988E (pt) 2014-04-03
PL2364988T3 (pl) 2014-08-29
KR20120044372A (ko) 2012-05-07
US20080213809A1 (en) 2008-09-04
EP1907408A1 (de) 2008-04-09
KR20140003637A (ko) 2014-01-09
DE102005035461A1 (de) 2007-02-15
EP1907408B1 (de) 2014-03-05
JP5650695B2 (ja) 2015-01-07
EP2364989A1 (de) 2011-09-14
WO2007012494B1 (de) 2007-03-29
PT1907408E (pt) 2014-03-28
US20160326567A1 (en) 2016-11-10
MX2008000946A (es) 2008-03-27
US10167497B2 (en) 2019-01-01
SG187511A1 (en) 2013-02-28
KR101035524B1 (ko) 2011-05-23
KR20080028507A (ko) 2008-03-31
KR101483829B1 (ko) 2015-01-16
EP2364989B1 (de) 2014-03-05
US8809013B2 (en) 2014-08-19
ES2453150T3 (es) 2014-04-04
CN101233144A (zh) 2008-07-30
EP2364988A1 (de) 2011-09-14

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