PL1907553T3 - Zmodyfikowane miejsca rekombinacji FRT oraz sposoby ich zastosowania - Google Patents

Zmodyfikowane miejsca rekombinacji FRT oraz sposoby ich zastosowania

Info

Publication number
PL1907553T3
PL1907553T3 PL06787308T PL06787308T PL1907553T3 PL 1907553 T3 PL1907553 T3 PL 1907553T3 PL 06787308 T PL06787308 T PL 06787308T PL 06787308 T PL06787308 T PL 06787308T PL 1907553 T3 PL1907553 T3 PL 1907553T3
Authority
PL
Poland
Prior art keywords
methods
recombination sites
frt recombination
modified frt
modified
Prior art date
Application number
PL06787308T
Other languages
English (en)
Inventor
Yumin Tao
Dennis Bidney
William J Gordon-Kamm
Leszek A Lyznik
Original Assignee
Pioneer Hi Bred Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred Int filed Critical Pioneer Hi Bred Int
Publication of PL1907553T3 publication Critical patent/PL1907553T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1051Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL06787308T 2005-07-18 2006-07-14 Zmodyfikowane miejsca rekombinacji FRT oraz sposoby ich zastosowania PL1907553T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70022505P 2005-07-18 2005-07-18
EP06787308A EP1907553B1 (en) 2005-07-18 2006-07-14 Modified frt recombination sites and methods of use
PCT/US2006/027380 WO2007011733A2 (en) 2005-07-18 2006-07-14 Modified frt recombination sites and methods of use

Publications (1)

Publication Number Publication Date
PL1907553T3 true PL1907553T3 (pl) 2013-02-28

Family

ID=37669396

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06787308T PL1907553T3 (pl) 2005-07-18 2006-07-14 Zmodyfikowane miejsca rekombinacji FRT oraz sposoby ich zastosowania

Country Status (8)

Country Link
US (10) US7736897B2 (pl)
EP (1) EP1907553B1 (pl)
BR (1) BRPI0612862A2 (pl)
CA (1) CA2615797C (pl)
ES (1) ES2390132T3 (pl)
MX (1) MX2008000764A (pl)
PL (1) PL1907553T3 (pl)
WO (1) WO2007011733A2 (pl)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7578598B2 (en) * 2006-11-13 2009-08-25 Black & Decker Inc. Battery charging work light
ES2390132T3 (es) * 2005-07-18 2012-11-06 Pioneer Hi-Bred International Inc. Sitios de recombinación FRT modificados y métodos de uso
US20070271629A1 (en) 2006-05-17 2007-11-22 Pioneer Hi-Bred International, Inc. Artificial plant minichromosomes
US8293533B2 (en) 2008-12-19 2012-10-23 E.I. Du Pont De Nemours And Company Site-specific integration and stacking of transgenes in soybean via DNA recombinase mediated cassette exchange
WO2011082310A2 (en) 2009-12-30 2011-07-07 Pioneer Hi-Bred International, Inc. Methods and compositions for targeted polynucleotide modification
US9207237B2 (en) 2010-08-23 2015-12-08 President And Fellows Of Harvard College Systems, methods, and workflows for optogenetics analysis
CA2838330C (en) 2010-08-23 2021-01-26 President And Fellows Of Harvard College Optogenetic probes for measuring membrane potential
CA2831144A1 (en) 2011-03-23 2012-09-27 Pioneer Hi-Bred International, Inc. Methods for producing a complex transgenic trait locus
EP2739739A1 (en) * 2011-08-03 2014-06-11 E. I. Du Pont de Nemours and Company Methods and compositions for targeted integration in a plant
CN102533744A (zh) * 2011-12-29 2012-07-04 中国科学院深圳先进技术研究院 基因表达盒及含有该基因表达盒的重组表达载体
AR089793A1 (es) 2012-01-27 2014-09-17 Du Pont Metodos y composiciones para generar locus de rasgos transgenicos complejos
US20140173775A1 (en) 2012-12-13 2014-06-19 Pioneer Hi-Bred International, Inc. Methods and compositions for producing and selecting transgenic plants
US10793867B2 (en) * 2013-03-15 2020-10-06 Monsanto Technology, Llc Methods for targeted transgene-integration using custom site-specific DNA recombinases
CA2918911A1 (en) 2013-07-31 2015-02-05 E.I. Du Pont De Nemours And Company Modification of soybean seed composition to enhance feed, food and other industrial applications of soybean products
CN120574876A (zh) 2013-08-22 2025-09-02 纳幕尔杜邦公司 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法
US10233456B2 (en) 2014-01-30 2019-03-19 The Board Of Trustees Of The University Of Arkansas Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
CN103882530B (zh) * 2014-03-26 2016-02-24 清华大学 用随机序列标记质粒对dna片段进行高通量两端测序的方法
WO2015164457A1 (en) 2014-04-22 2015-10-29 E. I. Du Pont De Nemours And Company Plastidic carbonic anhydrase genes for oil augmentation in seeds with increased dgat expression
WO2015195769A2 (en) 2014-06-18 2015-12-23 President And Fellows Of Harvard College Optogenetic probes for measuring membrane potential
US10676754B2 (en) 2014-07-11 2020-06-09 E I Du Pont De Nemours And Company Compositions and methods for producing plants resistant to glyphosate herbicide
KR102227771B1 (ko) * 2014-08-25 2021-03-16 삼성전자주식회사 나노구조 반도체 발광소자
MX2017002930A (es) 2014-09-12 2017-06-06 Du Pont Generacion de sitios de integracion especifica de sitio para loci de rasgos complejos en maiz y soja, y metodos de uso.
WO2016050917A1 (en) * 2014-10-01 2016-04-07 Dsm Ip Assets B.V. Methods for genomic modification
CN114736275A (zh) 2014-10-16 2022-07-12 先锋国际良种公司 具有改进的活性谱的杀昆虫多肽及其用途
WO2016115333A1 (en) 2015-01-15 2016-07-21 President And Fellows Of Harvard College Optical selection of cells
EP4118955A1 (en) 2015-03-19 2023-01-18 Pioneer Hi-Bred International, Inc. Compositions for accelerated trait introgression
BR112017017260A2 (pt) 2015-03-27 2018-04-17 Du Pont construções de dna, vetor, célula, plantas, semente, método de expressão de rna e método de modificação de local alvo
DK3341483T3 (da) 2015-08-28 2020-03-16 Pioneer Hi Bred Int Ochrobactrum-medieret transformation af planter
WO2017079026A1 (en) 2015-11-06 2017-05-11 E. I. Du Pont De Nemours And Company Generation of complex trait loci in soybean and methods of use
US10374872B2 (en) 2016-05-24 2019-08-06 Apstra, Inc. Configuring system resources for different reference architectures
GB201712678D0 (en) * 2017-08-07 2017-09-20 Glaxosmithkline Biologicals Sa Process for the manipulation of nucleic acids
CN111295093B (zh) 2017-10-30 2024-06-11 美国陶氏益农公司 用于转基因表达的植物启动子
WO2019165168A1 (en) 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
WO2020123887A2 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Novel crispr-cas systems for genome editing
WO2022072335A2 (en) 2020-09-30 2022-04-07 Pioneer Hi-Bred International, Inc. Rapid transformation of monocot leaf explants
EP4405375A1 (en) 2021-09-23 2024-07-31 President and Fellows of Harvard College Genetically encoded voltage indicators and uses thereof

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5990387A (en) 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
US5879918A (en) 1989-05-12 1999-03-09 Pioneer Hi-Bred International, Inc. Pretreatment of microprojectiles prior to using in a particle gun
US5658772A (en) * 1989-12-22 1997-08-19 E. I. Du Pont De Nemours And Company Site-specific recombination of DNA in plant cells
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
WO1993001283A1 (en) 1991-07-08 1993-01-21 The United States Of America As Represented By The Secretary Of Agriculture Selection-gene-free transgenic plants
EP0628082B1 (en) 1992-02-26 2001-05-16 Zeneca Mogen B.V. Agrobacterium strains capable of site-specific recombination
JP2952041B2 (ja) 1992-07-27 1999-09-20 パイオニア ハイ−ブレッド インターナショナル,インコーポレイテッド 培養ダイズ細胞のagrobacterium媒介形質転換の改良法
ES2156149T3 (es) * 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
CA2161881C (en) 1993-01-13 2001-03-27 A. Gururaj Rao High lysine derivatives of alpha-hordothionin
US5527695A (en) 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
DE4416784A1 (de) 1994-05-09 1995-11-30 Soft Gene Gmbh Methode zur Anreicherung von Zellen, die durch ballistischen Transfer modifiziert wurden
US5736369A (en) 1994-07-29 1998-04-07 Pioneer Hi-Bred International, Inc. Method for producing transgenic cereal plants
EG23907A (en) 1994-08-01 2007-12-30 Delta & Pine Land Co Control of plant gene expression
EP0828835A1 (en) 1995-06-02 1998-03-18 Pioneer Hi-Bred International, Inc. HIGH THREONINE DERIVATIVES OF $g(a)-HORDOTHIONIN
PL323635A1 (en) 1995-06-02 1998-04-14 Pioneer Hi Bred Int Derivatives of alpha-hordothionine of high methionine content
BR9610738A (pt) 1995-09-25 1999-07-13 Novartis Ag Integração aperfeiçoada de dna exógeno transferido para as células eucarióticas
US6051409A (en) * 1995-09-25 2000-04-18 Novartis Finance Corporation Method for achieving integration of exogenous DNA delivered by non-biological means to plant cells
US5677175A (en) 1995-10-13 1997-10-14 Purdue Research Foundation Plant pathogen induced proteins
US5703049A (en) 1996-02-29 1997-12-30 Pioneer Hi-Bred Int'l, Inc. High methionine derivatives of α-hordothionin for pathogen-control
US5753477A (en) 1996-03-19 1998-05-19 University Technology Corporation Magneto-biolistic methods
US5850016A (en) 1996-03-20 1998-12-15 Pioneer Hi-Bred International, Inc. Alteration of amino acid compositions in seeds
AUPN903196A0 (en) 1996-03-29 1996-04-26 Australian National University, The Single-step excision means
AU3495297A (en) 1996-07-08 1998-02-02 Pioneer Hi-Bred International, Inc. Transformation of zygote, egg or sperm cells and recovery of transformed plants from isolated embryo sacs
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
US7135608B1 (en) 1997-08-28 2006-11-14 The Salk Institute For Biological Studies Site-specific recombination in eukaryotes and constructs useful therefor
US6114600A (en) 1997-10-31 2000-09-05 The United States Of America As Represented By The Secretary Of Agriculture Resolution of complex integration patterns to obtain single copy transgenes
JP4206154B2 (ja) 1997-11-13 2009-01-07 大日本住友製薬株式会社 変異型loxP配列とその応用
ES2256972T3 (es) * 1997-11-18 2006-07-16 Pioneer Hi-Bred International, Inc. Metodo novedoso para la integracion de un adn foraneo dentro de genomas de eucariotas.
WO1999025821A1 (en) * 1997-11-18 1999-05-27 Pioneer Hi-Bred International, Inc. Compositions and methods for genetic modification of plants
AU745238C (en) * 1997-11-18 2003-02-27 Pioneer Hi-Bred International, Inc. Mobilization of viral genomes from T-DNA using site-specific recombination systems
CA2309719A1 (en) 1997-11-18 1999-05-27 Pioneer Hi-Bred International, Inc. Targeted manipulation of genes in plants
US6720475B1 (en) * 1997-11-18 2004-04-13 Pioneer Hi-Bred International, Inc. Modified nucleic acid sequence encoding FLP recombinase
US7102055B1 (en) * 1997-11-18 2006-09-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant
US5929301A (en) 1997-11-18 1999-07-27 Pioneer Hi-Bred International Nucleic acid sequence encoding FLP recombinase
EP0939120A1 (en) * 1998-02-27 1999-09-01 Gesellschaft für biotechnologische Forschung mbH (GBF) Method for marker-free repetitive DNA expression cassette exchange in the genome of cells or parts of cells
AU3928899A (en) 1998-04-28 1999-11-16 Novartis Ag Site-directed transformation of plants
US6781032B1 (en) 1998-08-14 2004-08-24 The Regents Of The University Of California Homologous recombination in plants
JP4478333B2 (ja) 1998-10-12 2010-06-09 大日本住友製薬株式会社 リコンビナーゼ発現細胞
EP1151124A1 (en) 1999-02-03 2001-11-07 The Children's Medical Center Corporation Gene repair involving in vivo excision of targeting dna
AU781628B2 (en) * 1999-07-14 2005-06-02 Clontech Laboratories, Inc. Recombinase-based methods for producing expression vectors and compositions for use in practicing the same
DK1234022T3 (da) 1999-07-23 2010-07-19 Univ California DNA-rekombination i eukaryote celler med bakteriofag PHIC31-rekombinationssystemet
US6746870B1 (en) * 1999-07-23 2004-06-08 The Regents Of The University Of California DNA recombination in eukaryotic cells by the bacteriophage PHIC31 recombination system
AU6529900A (en) 1999-08-09 2001-03-05 Monsanto Technology Llc Novel cloning methods and vectors
US7060499B1 (en) * 1999-09-30 2006-06-13 Izumu Saito DNA containing variant FRT sequences
US6849778B1 (en) * 1999-10-15 2005-02-01 Calgene Llc Methods and vectors for site-specific recombination in plant cell plastids
US7126041B1 (en) * 1999-12-10 2006-10-24 North Carolina State Unversity High efficiency gene targeting in plants
US20020023278A1 (en) * 2000-05-08 2002-02-21 Lyznik Leszek Alexander Genetic transformation in plants using site-specific recombination and wide hybridization
US7244560B2 (en) * 2000-05-21 2007-07-17 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AU7752001A (en) 2000-06-28 2002-01-08 Sungene Gmbh And Co Kgaa Binary vectors for improved transformation of plant systems
BR0112633A (pt) * 2000-07-21 2003-09-16 Us Agriculture Método para substituir, translocar e empilhar dna em genomas eucarióticos
DK1311661T3 (da) * 2000-08-14 2012-11-26 Us Gov Health & Human Serv Forøget homolog rekombination medieret ved lambda-rekombinationsproteiner
US7198924B2 (en) * 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US7449179B2 (en) * 2000-11-16 2008-11-11 Cornell Research Foundation, Inc. Vectors for conditional gene inactivation
US6696278B1 (en) * 2001-02-26 2004-02-24 Stratagene Method for transfer of DNA segments
US7074611B2 (en) * 2001-04-27 2006-07-11 Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
DE10131786A1 (de) 2001-07-04 2003-01-16 Sungene Gmbh & Co Kgaa Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen
US7041648B2 (en) 2001-08-03 2006-05-09 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Compositions and methods for treating female fertility
KR20040029132A (ko) * 2001-09-03 2004-04-03 독립행정법인농업생물자원연구소 피토크롬c의 발현억제에 의한 식물의 개화시기의 조절
DE60236182D1 (de) 2001-09-14 2010-06-10 Cellectis Zufällige integration von polynukleotide nach in vivo linearisierung
AU2002360986A1 (en) 2001-12-20 2003-07-09 Sungene Gmbh And Co. Kgaa Methods for the transformation of vegetal plastids
US20030167526A1 (en) 2002-01-14 2003-09-04 Pioneer Hi-Bred International Inc. Compositions and methods for identifying transformed cells
JP2005521400A (ja) 2002-03-29 2005-07-21 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 植物におけるラムダインテグラーゼ媒介型組換え
US7238854B2 (en) * 2002-04-11 2007-07-03 E. I. Du Pont De Nemours And Company Method of controlling site-specific recombination
AU2003247696A1 (en) * 2002-07-01 2004-01-19 E.I. Du Pont De Nemours And Company Method of controlling gene silencing using site-specific recombination
US20040137624A1 (en) * 2002-12-27 2004-07-15 Lowe Brenda A. Methods of site-directed transformation
ES2320228T3 (es) 2003-11-18 2009-05-20 Bayer Bioscience N.V. Insercion mejorada direccionada de dna en las plantas.
US7935862B2 (en) 2003-12-02 2011-05-03 Syngenta Participations Ag Targeted integration and stacking of DNA through homologous recombination
US20060288444A1 (en) 2004-08-13 2006-12-21 Mccarroll Robert Soybean polymorphisms and methods of genotyping
AP2693A (en) 2005-05-27 2013-07-16 Monsanto Technology Llc Soybean event MON89788 and methods for detection thereof
ES2390132T3 (es) 2005-07-18 2012-11-06 Pioneer Hi-Bred International Inc. Sitios de recombinación FRT modificados y métodos de uso
US20070016985A1 (en) 2005-07-18 2007-01-18 Pioneer Hi-Bred International, Inc. Particle Preparation for Direct-Delivery Transformation
WO2007050715A2 (en) 2005-10-26 2007-05-03 Integrated Plant Genetics, Inc. Compositions and methods for safe delivery of biologically-active plant transformation agents using non-fibrous silicon carbide powder
US20080083042A1 (en) 2006-08-14 2008-04-03 David Butruille Maize polymorphisms and methods of genotyping
CL2008001865A1 (es) 2007-06-22 2008-12-26 Monsanto Technology Llc Método para identificar una muestra de germoplasma vegetal con un genotipo que modula el rendimiento de una caracteristica, y célula vegetal que contiene al menos una región genómatica identificada para modular el rendiemiento de transgenes.

Also Published As

Publication number Publication date
US20160108412A1 (en) 2016-04-21
US9234194B2 (en) 2016-01-12
US9777284B2 (en) 2017-10-03
US20070015195A1 (en) 2007-01-18
US20130052739A1 (en) 2013-02-28
CA2615797A1 (en) 2007-01-25
US20080047031A1 (en) 2008-02-21
US20170369893A1 (en) 2017-12-28
US20100173801A1 (en) 2010-07-08
US8318493B2 (en) 2012-11-27
BRPI0612862A2 (pt) 2010-11-30
US8900869B2 (en) 2014-12-02
US7736897B2 (en) 2010-06-15
US11225668B2 (en) 2022-01-18
ES2390132T3 (es) 2012-11-06
WO2007011733A2 (en) 2007-01-25
US20150044771A1 (en) 2015-02-12
EP1907553A2 (en) 2008-04-09
MX2008000764A (es) 2008-03-24
WO2007011733A3 (en) 2007-09-07
US8586361B2 (en) 2013-11-19
US20110047655A1 (en) 2011-02-24
US20190194673A1 (en) 2019-06-27
US20100192263A1 (en) 2010-07-29
EP1907553B1 (en) 2012-08-22
CA2615797C (en) 2014-04-29

Similar Documents

Publication Publication Date Title
PL1907553T3 (pl) Zmodyfikowane miejsca rekombinacji FRT oraz sposoby ich zastosowania
IL188420A0 (en) Methods and compositions with enhanced therapeutic activity
TWI561237B (en) Substituted dihydropyrazolones and their use
ZA200710173B (en) Tygecycline and methods of preparing 9-nitrominocycline
EP1945137A4 (en) PARTLY COVERED STENT DEVICES AND APPLICATION METHODS
IL186490A0 (en) Multicyclic compounds and methods of their use
IL185280A0 (en) Tetrahydroindolone and tetrahydroindazolone derivatives
IL191072A0 (en) Therapeutic compositions and methods
EP1987397A4 (en) APPARATUS AND METHODS OF WRITING
IL185309A0 (en) Isoqunoline compounds and methods of use thereof
IL247957A0 (en) Anti-ephrinb2 antibodies and methods of using them
ZA200807614B (en) Buprenorphine derivatives and uses thereof
IL189252A0 (en) Dihydroxyanthraquinones and their use
EP2121703A4 (en) THIENOPYRIMIDIN-4-ON- AND THIENOPYRIDAZIN-7-ONDERIVATES AS MCH-RL ANTAGONISTS
EP1968526A4 (en) FOAMING DENTAL COMPOSITIONS AND METHODS
EP1737565A4 (en) COS CLAUS CONFIGURATIONS AND METHODS
EP2077262A4 (en) IMINOPYRIDINE DERIVATIVE AND USE THEREOF
IL190583A0 (en) Pth formulations and methods of use
EP1951671A4 (en) NEW PULLEOMUTILINE DERIVATIVES AND THEIR USE
IL186277A0 (en) Dnt-maleate and methods of preparation thereof
EP1845984A4 (en) METHYLPHENIDATE DERIVATIVES AND THEIR USES
GB0501348D0 (en) Compositions and methods
GB0610059D0 (en) Uses and methods
GB0505620D0 (en) Methods and materials therefor
GB0624999D0 (en) Methods and users