PL1924580T3 - Związki niesteroidowe użyteczne jako modulatory receptora glukokortykoidów - Google Patents

Związki niesteroidowe użyteczne jako modulatory receptora glukokortykoidów

Info

Publication number
PL1924580T3
PL1924580T3 PL06764340T PL06764340T PL1924580T3 PL 1924580 T3 PL1924580 T3 PL 1924580T3 PL 06764340 T PL06764340 T PL 06764340T PL 06764340 T PL06764340 T PL 06764340T PL 1924580 T3 PL1924580 T3 PL 1924580T3
Authority
PL
Poland
Prior art keywords
compounds useful
receptor modulators
glucocorticoid receptor
steroidal compounds
steroidal
Prior art date
Application number
PL06764340T
Other languages
English (en)
Inventor
Ralf Plate
Christiaan Gerardus Johannes Maria Jans
Original Assignee
Msd Oss Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Msd Oss Bv filed Critical Msd Oss Bv
Publication of PL1924580T3 publication Critical patent/PL1924580T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL06764340T 2005-08-29 2006-08-25 Związki niesteroidowe użyteczne jako modulatory receptora glukokortykoidów PL1924580T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05107896 2005-08-29
EP06764340A EP1924580B1 (en) 2005-08-29 2006-08-25 Non-steroidal compounds useful as glucocorticoid receptor modulators
PCT/EP2006/065696 WO2007025938A1 (en) 2005-08-29 2006-08-25 Non-steroidal compounds useful as glucocorticoid receptor modulators

Publications (1)

Publication Number Publication Date
PL1924580T3 true PL1924580T3 (pl) 2009-07-31

Family

ID=35466054

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06764340T PL1924580T3 (pl) 2005-08-29 2006-08-25 Związki niesteroidowe użyteczne jako modulatory receptora glukokortykoidów

Country Status (30)

Country Link
US (1) US8575152B2 (pl)
EP (1) EP1924580B1 (pl)
JP (1) JP5191383B2 (pl)
KR (1) KR20080040024A (pl)
CN (1) CN101304999B (pl)
AR (1) AR058027A1 (pl)
AT (1) ATE421516T1 (pl)
AU (1) AU2006286524B2 (pl)
BR (1) BRPI0615412A2 (pl)
CA (1) CA2621229A1 (pl)
CY (1) CY1109041T1 (pl)
DE (1) DE602006005006D1 (pl)
DK (1) DK1924580T3 (pl)
EC (1) ECSP088289A (pl)
ES (1) ES2320273T3 (pl)
HR (1) HRP20090116T3 (pl)
IL (1) IL189463A (pl)
MY (1) MY145591A (pl)
NO (1) NO20080940L (pl)
NZ (1) NZ566005A (pl)
PE (1) PE20070331A1 (pl)
PL (1) PL1924580T3 (pl)
PT (1) PT1924580E (pl)
RS (1) RS50763B (pl)
RU (1) RU2420528C2 (pl)
SI (1) SI1924580T1 (pl)
TW (1) TWI375676B (pl)
UA (1) UA92024C2 (pl)
WO (1) WO2007025938A1 (pl)
ZA (1) ZA200801599B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130717B (zh) * 2011-11-29 2015-04-01 上海博康精细化工有限公司 二苯并氮卓酮的制备方法
WO2025255469A1 (en) * 2024-06-06 2025-12-11 Psammiad Therapeutics, Inc. Compounds and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657250A (en) * 1970-02-10 1972-04-18 Ayerst Mckenna & Harrison Benzocycloheptaisoquinoline derivatives
IL36085A (en) * 1970-02-10 1974-09-10 Ayerst Mckenna & Harrison Octahydrobenzo(6,7)cyclohepta(1,2,3-d,a)pyrido(or pyrrolo)-(2,1-a)isoquinolines and decahydrobenzo-(6,7)cyclohepta-(1,2,3-d,e)azepino(2,1-a)isoquinolines and their preparation
NL7305811A (pl) * 1973-04-26 1974-10-29
US4016161A (en) * 1974-04-24 1977-04-05 Akzona Incorporated Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines
EP1043325B1 (en) * 1994-12-22 2004-06-16 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
IL146057A (en) * 2000-10-27 2007-09-20 Pfizer Prod Inc A process for the preparation of modulators of a non-steroidal glucocorticoid receptor
TWI297685B (en) * 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
EP1534273A4 (en) 2002-07-18 2007-08-22 Bristol Myers Squibb Co MODULATORS OF THE GLUCOCORTICOID RECEPTOR AND METHOD

Also Published As

Publication number Publication date
UA92024C2 (ru) 2010-09-27
RU2008112206A (ru) 2009-10-10
NZ566005A (en) 2010-01-29
CN101304999A (zh) 2008-11-12
RU2420528C2 (ru) 2011-06-10
AU2006286524B2 (en) 2011-06-16
EP1924580B1 (en) 2009-01-21
DK1924580T3 (da) 2009-05-11
BRPI0615412A2 (pt) 2012-12-04
CA2621229A1 (en) 2007-03-08
ECSP088289A (es) 2008-04-28
KR20080040024A (ko) 2008-05-07
US8575152B2 (en) 2013-11-05
CN101304999B (zh) 2011-11-16
ES2320273T3 (es) 2009-05-20
TWI375676B (en) 2012-11-01
AU2006286524A1 (en) 2007-03-08
AR058027A1 (es) 2008-01-23
PE20070331A1 (es) 2007-04-16
NO20080940L (no) 2008-05-05
WO2007025938A1 (en) 2007-03-08
RS50763B (sr) 2010-08-31
DE602006005006D1 (de) 2009-03-12
ATE421516T1 (de) 2009-02-15
JP2009506093A (ja) 2009-02-12
IL189463A0 (en) 2008-06-05
US20080188459A1 (en) 2008-08-07
HRP20090116T3 (en) 2009-04-30
SI1924580T1 (sl) 2009-06-30
PT1924580E (pt) 2009-04-01
TW200745105A (en) 2007-12-16
MY145591A (en) 2012-02-29
IL189463A (en) 2011-07-31
CY1109041T1 (el) 2014-07-02
EP1924580A1 (en) 2008-05-28
JP5191383B2 (ja) 2013-05-08
ZA200801599B (en) 2009-01-28

Similar Documents

Publication Publication Date Title
ZA200803452B (en) Modulation of glucocorticoid receptor expression
SI1928845T1 (sl) Aminodiazepini kot modulatorji Tollu podobnega receptorja
HUS1700010I1 (hu) Új vegyületek mint ópioid receptor modulátorok
EP1931632A4 (en) USEFUL INDOOR CONNECTIONS
ZA200705458B (en) Aminophenyl derivatives as selective androgen receptor modulators
GB0400440D0 (en) Receptor modulators
SI2094658T1 (sl) Spojine tetrahidrociklopenta(b)indola kot modulatorji androgenskega receptorja
ZA200705449B (en) 2-phenyl-indoles as prostaglandin D2 receptor antagonists
EP2097384A4 (en) INDOZALYL SULFOMNAMIDE DERIVATIVES USEFUL AS MODULATORS OF GLUCOCORTICOIDS
ZA200805242B (en) GABAB receptor modulators
IL191710A0 (en) Glucocorticoid receptor modulators as antiinflammatory agents
ZA200710018B (en) Microcapsule composition
IL184374A0 (en) Non steroidal glucocorticoid receptor modulators
ZA200800690B (en) Non-steroidal progesterone receptor modulators
ZA200801599B (en) Non-steroidal compounds useful as glucocorticoid receptor modulators
IL184532A0 (en) Novel adenosine a3 receptor modulators
ZA200806237B (en) Cannibinoid receptor modulators
HK1114102A (en) Non-steroidal compounds useful as glucocorticoid receptor modulators
GB0516946D0 (en) Receptor
AU2007901958A0 (en) Non-steroidal compounds
GB0522394D0 (en) Receptor
GB0522484D0 (en) Receptor
GB0522077D0 (en) Receptor
GB0510253D0 (en) Receptor
HK1122811A (en) Cannibinoid receptor modulators