PL2034015T3 - Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne - Google Patents

Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne

Info

Publication number
PL2034015T3
PL2034015T3 PL07744493T PL07744493T PL2034015T3 PL 2034015 T3 PL2034015 T3 PL 2034015T3 PL 07744493 T PL07744493 T PL 07744493T PL 07744493 T PL07744493 T PL 07744493T PL 2034015 T3 PL2034015 T3 PL 2034015T3
Authority
PL
Poland
Prior art keywords
immunostimulatory oligonucleotide
pharmaceutical application
pharmaceutical
application
immunostimulatory
Prior art date
Application number
PL07744493T
Other languages
English (en)
Inventor
Tomokatsu Iwamura
Hideki Narumi
Hajime Masumoto
Akihito Kaneda
Akiko Soneda
Shizuo Akira
Original Assignee
Toray Industries
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries, Univ Osaka filed Critical Toray Industries
Publication of PL2034015T3 publication Critical patent/PL2034015T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL07744493T 2006-05-31 2007-05-31 Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne PL2034015T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006152544 2006-05-31
JP2007046556 2007-02-27
PCT/JP2007/061105 WO2007139190A1 (ja) 2006-05-31 2007-05-31 免疫刺激オリゴヌクレオチド及びその医薬用途
EP07744493A EP2034015B1 (en) 2006-05-31 2007-05-31 Immunostimulatory oligonucleotide and pharmaceutical application thereof

Publications (1)

Publication Number Publication Date
PL2034015T3 true PL2034015T3 (pl) 2012-11-30

Family

ID=38778707

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07744493T PL2034015T3 (pl) 2006-05-31 2007-05-31 Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne

Country Status (11)

Country Link
US (1) US8592566B2 (pl)
EP (1) EP2034015B1 (pl)
JP (1) JP5161770B2 (pl)
KR (1) KR101065760B1 (pl)
CN (1) CN101460620B (pl)
AU (1) AU2007268534B2 (pl)
CA (1) CA2653939C (pl)
DK (1) DK2034015T3 (pl)
ES (1) ES2389112T3 (pl)
PL (1) PL2034015T3 (pl)
WO (1) WO2007139190A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100965A1 (ja) * 2003-05-15 2004-11-25 Japan Science And Technology Agency 免疫刺激剤
BRPI0923225A2 (pt) 2008-12-02 2016-10-04 Chiralgen Ltd metodo para sintese de acidos nucleicos modificados no atomo de fosforo
EP2451461A4 (en) 2009-07-06 2013-05-29 Ontorii Inc NOVEL NUCLEIC ACID PRODRUGS AND METHOD OF USE THEREOF
EP2484378A4 (en) 2009-09-30 2013-05-22 Toray Industries HEPATITIS C VIRUS VACCINE COMPOSITION
HRP20181039T1 (hr) * 2010-05-28 2018-08-24 Zoetis Belgium S.A. Cjepiva koja sadrže kolesterol i cpg kao jedine molekule koje nose adjuvans
DK2620428T3 (da) 2010-09-24 2019-07-01 Wave Life Sciences Ltd Asymmetrisk hjælpegruppe
DK2640426T3 (en) * 2010-11-16 2016-05-02 Selecta Biosciences Inc Immunostimulating Oligonucleotides
CN107365339A (zh) 2011-07-19 2017-11-21 波涛生命科学有限公司 合成官能化核酸的方法
DK2872147T3 (da) 2012-07-13 2023-02-20 Wave Life Sciences Ltd Fremgangsmåde til fremstilling af kirale oligonukleotider
SG11201500243WA (en) * 2012-07-13 2015-04-29 Shin Nippon Biomedical Lab Ltd Chiral nucleic acid adjuvant
WO2014010250A1 (en) 2012-07-13 2014-01-16 Chiralgen, Ltd. Asymmetric auxiliary group
WO2015108046A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤
EP3095461A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
EP3095459A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having antitumor effect and antitumor agent
EP3094728B1 (en) 2014-01-16 2022-03-09 Wave Life Sciences Ltd. Chiral design
EP3238727B1 (en) 2014-12-25 2023-01-18 National Institutes of Biomedical Innovation, Health and Nutrition Non-aggregating immunostimulatory oligonucleotides
CN117965536A (zh) 2015-07-22 2024-05-03 波涛生命科学有限公司 寡核苷酸组合物及其方法
CN118909014B (zh) * 2023-07-21 2025-11-28 南京吉盛澳玛生物医药有限公司 具有调节机体免疫能力的CpG寡聚脱氧核苷酸及其应用

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0315711A (ja) 1989-03-14 1991-01-24 Kazuko Mizogami 距離測定用標識棒
JPH0458179A (ja) 1990-06-26 1992-02-25 Mazda Motor Corp 障害物検出装置
JPH04352724A (ja) 1990-07-27 1992-12-07 Mitsui Toatsu Chem Inc 免疫調節型治療剤
EP0468520A3 (en) 1990-07-27 1992-07-01 Mitsui Toatsu Chemicals, Inc. Immunostimulatory remedies containing palindromic dna sequences
AU713040B2 (en) 1994-07-15 1999-11-18 University Of Iowa Research Foundation, The Immunomodulatory oligonucleotides
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6239116B1 (en) * 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
CA2244946C (en) * 1996-01-30 2010-04-13 The Regents Of The University Of California Gene expression vectors which generate an antigen specific immune response and methods of using the same
JP3130799B2 (ja) 1996-06-28 2001-01-31 川崎重工業株式会社 発電方法及び装置
WO1998055609A1 (en) 1997-06-06 1998-12-10 The Regents Of The University Of California Inhibitors of dna immunostimulatory sequence activity
PT1009413E (pt) * 1997-09-05 2007-05-31 Univ California Utilização de oligonucleótidos imumoestimulantes para a prevenção ou tratamento da asma.
JP3669845B2 (ja) 1998-08-25 2005-07-13 株式会社タカラ 人形体の製造方法
EP1176966B1 (en) 1999-04-12 2013-04-03 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Oligodeoxynucleotide and its use to induce an immune response
US6977245B2 (en) * 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
US6949520B1 (en) * 1999-09-27 2005-09-27 Coley Pharmaceutical Group, Inc. Methods related to immunostimulatory nucleic acid-induced interferon
IL148844A0 (en) 1999-09-27 2002-09-12 Coley Pharm Group Inc Methods related to immunostimulatory nucleic acid-induced interferon
KR100359753B1 (ko) 1999-12-21 2002-11-09 주식회사 제넥신 면역조절능력 및 안전성이 증가되고 ｄＧ 연속서열이결합된 포스포다이에스터 ＣｐＧ올리고데옥시뉴클레오티드 변형체
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
US20020098199A1 (en) * 2000-03-10 2002-07-25 Gary Van Nest Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences
JP2003015711A (ja) 2001-07-03 2003-01-17 Yaskawa Electric Corp ドライブシステムのプログラム更新方法
EA007232B1 (ru) 2001-08-17 2006-08-25 Коли Фармасьютикал Гмбх Иммуностимулирующие олигонуклеотиды, содержащие комбинацию мотивов и обладающие повышенной активностью
JP2004058179A (ja) 2002-07-25 2004-02-26 Nippon Densan Corp 電解加工用電極工具
NZ540098A (en) * 2002-10-29 2008-09-26 Coley Pharmaceutical Group Ltd Use of CPG oligonucleotides in the treatment of hepatitis C virus infection
DK1992635T3 (da) 2002-12-23 2012-03-05 Dynavax Tech Corp Oligonukleotider med immunstimulatorisk sekvens og fremgangsmåder til anvendelse af disse
JP4726630B2 (ja) * 2003-01-16 2011-07-20 イデラ ファーマシューティカルズ インコーポレイテッド 修飾された免疫賦活性ジヌクレオチドを用いることによるオリゴヌクレオチドに基づく化合物の免疫賦活特性の調節
JP2004287102A (ja) 2003-03-20 2004-10-14 Fuji Xerox Co Ltd 画像形成方法
JP4874801B2 (ja) 2003-06-11 2012-02-15 イデラ ファーマシューティカルズ インコーポレイテッド 安定化免疫調節オリゴヌクレオチド
JP2005014110A (ja) 2003-06-23 2005-01-20 Daishowa Seiki Co Ltd 押圧装置
WO2005014110A1 (en) 2003-07-22 2005-02-17 Cytos Biotechnology Ag Cpg-packaged liposomes
JP3976742B2 (ja) * 2004-02-27 2007-09-19 江守商事株式会社 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド
JP2006035939A (ja) 2004-07-23 2006-02-09 Denso Corp 電気ヒータ
JP2008000001A (ja) 2004-09-30 2008-01-10 Osaka Univ 免疫刺激オリゴヌクレオチドおよびその医薬用途

Also Published As

Publication number Publication date
US8592566B2 (en) 2013-11-26
JP5161770B2 (ja) 2013-03-13
CA2653939C (en) 2013-01-22
EP2034015A1 (en) 2009-03-11
JPWO2007139190A1 (ja) 2009-10-15
CN101460620B (zh) 2012-02-15
US20090263413A1 (en) 2009-10-22
EP2034015A4 (en) 2010-03-17
ES2389112T3 (es) 2012-10-23
CA2653939A1 (en) 2007-12-06
WO2007139190A1 (ja) 2007-12-06
EP2034015B1 (en) 2012-07-11
AU2007268534B2 (en) 2011-07-14
KR101065760B1 (ko) 2011-09-19
KR20090018798A (ko) 2009-02-23
AU2007268534A1 (en) 2007-12-06
DK2034015T3 (da) 2012-10-15
CN101460620A (zh) 2009-06-17

Similar Documents

Publication Publication Date Title
IL194751A0 (en) Drugs and uses
EP2056835A4 (en) PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
IL242883B (en) Aryl-amino and heteroaryl-amino converted deoxazolines and pharmaceutical preparations containing them
IL184563A (en) Pharmaceutical foam formulations and their use
DK2034015T3 (da) Immunstimulerende oligonucleotid og farmaceutisk anvendelse heraf
IL194007A0 (en) Pharmaceutical composition comprising anti-mirna antisense oligonucleotides
SG10201406016SA (en) Pharmaceutical composition comprising anti-mirna antisense oligonucleotides
ZA200810323B (en) Fkbp-l and uses thereof
ZA200902823B (en) Oligoribonucleotides and uses thereof
IL204442A (en) Inhibitors of atpase-0fif, medicinal preparations containing them and their use
LT2064327T (lt) Dbait ir jų panaudojimas
IL193211A (en) Derivatives of Indzol-Troaril and pharmaceutical preparations containing them
IL193700A0 (en) Medicaments and proteins
PL2094849T3 (pl) Długotrwała zmiana przebiegu choroby z zastosowaniem oligonukleotydów immunostymulujących
ZA200903906B (en) Carboranylporphyrins and uses thereof
EP1890677A4 (en) PHARMACEUTICAL COMPOSITIONS AND THEIR USE
EP2025667A4 (en) 9, 10-SECOPREGNANDERIVAT AND MEDICINAL PRODUCTS
ZA200808420B (en) Pharmaceutical composition comprising anti-mirna anti-sense oligonucleotides
GB0614586D0 (en) Pharmaceutical Formulation
IL192824A (en) Peptide compounds, pharmaceuticals containing them and their use
IL197883A0 (en) Combination drug
GB0516069D0 (en) Pharmaceutical and use thereof
IL198160A0 (en) Pharmaceutical formulations
GB0610090D0 (en) Particulate drug compositions and their uses
GB0614365D0 (en) Pharmaceutical compositions and their use