DK2034015T3 - Immunstimulerende oligonucleotid og farmaceutisk anvendelse heraf - Google Patents

Immunstimulerende oligonucleotid og farmaceutisk anvendelse heraf

Info

Publication number
DK2034015T3
DK2034015T3 DK07744493.3T DK07744493T DK2034015T3 DK 2034015 T3 DK2034015 T3 DK 2034015T3 DK 07744493 T DK07744493 T DK 07744493T DK 2034015 T3 DK2034015 T3 DK 2034015T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical use
immunostimulatory oligonucleotide
immunostimulatory
oligonucleotide
pharmaceutical
Prior art date
Application number
DK07744493.3T
Other languages
English (en)
Inventor
Hajime Masumoto
Akihito Kaneda
Tomokatsu Iwamura
Hideki Narumi
Akiko Soneda
Shizuo Akira
Original Assignee
Toray Industries
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries, Univ Osaka filed Critical Toray Industries
Application granted granted Critical
Publication of DK2034015T3 publication Critical patent/DK2034015T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK07744493.3T 2006-05-31 2007-05-31 Immunstimulerende oligonucleotid og farmaceutisk anvendelse heraf DK2034015T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006152544 2006-05-31
JP2007046556 2007-02-27
PCT/JP2007/061105 WO2007139190A1 (ja) 2006-05-31 2007-05-31 免疫刺激オリゴヌクレオチド及びその医薬用途

Publications (1)

Publication Number Publication Date
DK2034015T3 true DK2034015T3 (da) 2012-10-15

Family

ID=38778707

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07744493.3T DK2034015T3 (da) 2006-05-31 2007-05-31 Immunstimulerende oligonucleotid og farmaceutisk anvendelse heraf

Country Status (11)

Country Link
US (1) US8592566B2 (da)
EP (1) EP2034015B1 (da)
JP (1) JP5161770B2 (da)
KR (1) KR101065760B1 (da)
CN (1) CN101460620B (da)
AU (1) AU2007268534B2 (da)
CA (1) CA2653939C (da)
DK (1) DK2034015T3 (da)
ES (1) ES2389112T3 (da)
PL (1) PL2034015T3 (da)
WO (1) WO2007139190A1 (da)

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JP4850512B2 (ja) * 2003-05-15 2012-01-11 独立行政法人科学技術振興機構 免疫刺激剤
RU2572826C2 (ru) 2008-12-02 2016-01-20 Чиралджен, Лтд. Способ синтеза модифицированных по атому фосфора нуклеиновых кислот
CA2767253A1 (en) 2009-07-06 2011-01-13 Ontorii, Inc. Novel nucleic acid prodrugs and methods of use thereof
WO2011040535A1 (ja) 2009-09-30 2011-04-07 東レ株式会社 Ｃ型肝炎ウイルスワクチン組成物
NZ603527A (en) * 2010-05-28 2014-10-31 Zoetis Belgium S A Vaccines comprising cholesterol and cpg as sole adjuvant - carrier molecules
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
CA2817746A1 (en) * 2010-11-16 2012-05-24 Selecta Biosciences, Inc. Immunostimulatory oligonucleotid
AU2012284265B2 (en) 2011-07-19 2017-08-17 Wave Life Sciences Ltd. Methods for the synthesis of functionalized nucleic acids
JP6453212B2 (ja) 2012-07-13 2019-01-16 ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． キラル制御
CN104684923B (zh) * 2012-07-13 2018-09-28 株式会社新日本科学 手性核酸佐剂
SG11201500239VA (en) 2012-07-13 2015-03-30 Wave Life Sciences Japan Asymmetric auxiliary group
JPWO2015108046A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤
WO2015108048A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
WO2015108047A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
ES2917473T3 (es) 2014-01-16 2022-07-08 Wave Life Sciences Ltd Diseño quiral
JP6715775B2 (ja) * 2014-12-25 2020-07-01 国立研究開発法人医薬基盤・健康・栄養研究所 非凝集性免疫賦活化オリゴヌクレオチド
CN108135921B (zh) 2015-07-22 2023-10-17 波涛生命科学有限公司 寡核苷酸组合物及其方法
CN118909014B (zh) * 2023-07-21 2025-11-28 南京吉盛澳玛生物医药有限公司 具有调节机体免疫能力的CpG寡聚脱氧核苷酸及其应用

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JPH0458179A (ja) 1990-06-26 1992-02-25 Mazda Motor Corp 障害物検出装置
EP0468520A3 (en) 1990-07-27 1992-07-01 Mitsui Toatsu Chemicals, Inc. Immunostimulatory remedies containing palindromic dna sequences
JPH04352724A (ja) 1990-07-27 1992-12-07 Mitsui Toatsu Chem Inc 免疫調節型治療剤
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EP0879284B1 (en) * 1996-01-30 2009-07-29 The Regents of The University of California Gene expression vectors which generate an antigen specific immune response and methods of using the same
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Also Published As

Publication number Publication date
EP2034015A1 (en) 2009-03-11
EP2034015A4 (en) 2010-03-17
US20090263413A1 (en) 2009-10-22
CN101460620A (zh) 2009-06-17
AU2007268534B2 (en) 2011-07-14
EP2034015B1 (en) 2012-07-11
CA2653939C (en) 2013-01-22
PL2034015T3 (pl) 2012-11-30
US8592566B2 (en) 2013-11-26
JP5161770B2 (ja) 2013-03-13
AU2007268534A1 (en) 2007-12-06
CN101460620B (zh) 2012-02-15
KR20090018798A (ko) 2009-02-23
KR101065760B1 (ko) 2011-09-19
CA2653939A1 (en) 2007-12-06
WO2007139190A1 (ja) 2007-12-06
JPWO2007139190A1 (ja) 2009-10-15
ES2389112T3 (es) 2012-10-23

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