PL2040689T3 - Roztwór zawierający N-acetylocysteinę i kwas glukonowy oraz sposoby redukowania, leczenia i zapobiegania stresowi oksydacyjnemu i aktywacji komórek - Google Patents

Roztwór zawierający N-acetylocysteinę i kwas glukonowy oraz sposoby redukowania, leczenia i zapobiegania stresowi oksydacyjnemu i aktywacji komórek

Info

Publication number: PL2040689T3
Authority: PL; Poland
Prior art keywords: solution; methods; treat; reduce; cell activation
Prior art date: 2006-06-22

Application number

PL07764759T

Other languages

English (en)

Inventor

Reinhold Deppisch

Werner Beck

Andrea Schnell

Hans-Rainer Drieschmanns

Original Assignee

Gambro Lundia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-22

Filing date

2007-06-21

Publication date

2011-04-29

2007-06-21 Application filed by Gambro Lundia Ab filed Critical Gambro Lundia Ab

2011-04-29 Publication of PL2040689T3 publication Critical patent/PL2040689T3/pl

Links

RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 title abstract 2
PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title abstract 2
229960004308 acetylcysteine Drugs 0.000 title abstract 2
230000020411 cell activation Effects 0.000 title abstract 2
235000012208 gluconic acid Nutrition 0.000 title abstract 2
239000000174 gluconic acid Substances 0.000 title abstract 2
230000036542 oxidative stress Effects 0.000 title abstract 2
239000000243 solution Substances 0.000 abstract 5
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 abstract 2
239000007924 injection Substances 0.000 abstract 2
238000002347 injection Methods 0.000 abstract 2
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract 1
108010024636 Glutathione Proteins 0.000 abstract 1
229930003268 Vitamin C Natural products 0.000 abstract 1
230000017531 blood circulation Effects 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
239000000385 dialysis solution Substances 0.000 abstract 1
229960003180 glutathione Drugs 0.000 abstract 1
238000001802 infusion Methods 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
235000019154 vitamin C Nutrition 0.000 abstract 1
239000011718 vitamin C Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
Zoology (AREA)
Biochemistry (AREA)
External Artificial Organs (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

PL07764759T 2006-06-22 2007-06-21 Roztwór zawierający N-acetylocysteinę i kwas glukonowy oraz sposoby redukowania, leczenia i zapobiegania stresowi oksydacyjnemu i aktywacji komórek PL2040689T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US80548906P	2006-06-22	2006-06-22
PCT/EP2007/005466 WO2007147590A2 (en)	2006-06-22	2007-06-21	Solution and method to reduce, treat and/or prevent oxidative stress and cell activation
EP07764759A EP2040689B1 (en)	2006-06-22	2007-06-21	Solution comprising n-acetylcysteine and gluconic acid, and methods to reduce, treat and/or prevent oxidative stress and cell activation

Publications (1)

Publication Number	Publication Date
PL2040689T3 true PL2040689T3 (pl)	2011-04-29

Family

ID=38614318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL07764759T PL2040689T3 (pl)	2006-06-22	2007-06-21	Roztwór zawierający N-acetylocysteinę i kwas glukonowy oraz sposoby redukowania, leczenia i zapobiegania stresowi oksydacyjnemu i aktywacji komórek

Country Status (8)

Country	Link
US (1)	US20100204328A1 (pl)
EP (1)	EP2040689B1 (pl)
AT (1)	ATE489950T1 (pl)
CA (1)	CA2655644C (pl)
DE (1)	DE602007010938D1 (pl)
ES (1)	ES2355853T3 (pl)
PL (1)	PL2040689T3 (pl)
WO (1)	WO2007147590A2 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010112547A1 (en) *	2009-03-31	2010-10-07	Gambro Lundia Ab	Dialysis precursor composition
CN107922922A (zh)	2015-08-24	2018-04-17	维特罗利夫瑞典股份公司	培养基
RU2709501C1 (ru) *	2019-10-15	2019-12-18	Виктор Александрович Сисев	Фармацевтическая композиция для парентерального капельного введения

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3583880D1 (de) *	1984-04-09	1991-10-02	Takeda Chemical Industries Ltd	Stabile interleukin-2-zusammensetzung.
JP3714689B2 (ja) *	1994-10-27	2005-11-09	ユニチカ株式会社	ビリルビン測定用試薬
US5871769A (en) *	1996-01-18	1999-02-16	Fleming & Company, Pharmaceuticals	Methods and compositions for the prevention and treatment of diabetes mellitus
IT1312086B1 (it) *	1999-04-21	2002-04-04	Zambon Spa	Uso della nac per la preparazione di un medicamento adatto allasomministrazione endovenosa per la prevenzione dello stress
EP1062879B1 (en) *	1999-06-26	2003-08-27	B. Braun Melsungen Ag	Aqueous solution for the parenteral nutrition
KR100390630B1 (ko) *	1999-07-02	2003-07-07	이희발	항 산화제를 함유한 복막투석액
ATE311203T1 (de) *	1999-10-15	2005-12-15	Dow Global Technologies Inc	Dialyselösung die polyglycol als osmotischen mittels enthält
US7014990B2 (en) *	2000-10-13	2006-03-21	Ben O'Mar Arrington	Machine perfusion solution for organ and biological tissue preservation
US6955816B2 (en) *	2001-11-16	2005-10-18	Klysz Beatrice M	Anti-aging skin care composition and uses thereof
JP4894219B2 (ja) *	2004-10-15	2012-03-14	ニプロ株式会社	ビタミンｂ群配合末梢静脈栄養輸液
WO2007046757A1 (en) *	2005-10-17	2007-04-26	Gambro Lundia Ab	Extracorporeal blood cleaning

2007
- 2007-06-21 ES ES07764759T patent/ES2355853T3/es active Active
- 2007-06-21 EP EP07764759A patent/EP2040689B1/en active Active
- 2007-06-21 DE DE602007010938T patent/DE602007010938D1/de active Active
- 2007-06-21 CA CA2655644A patent/CA2655644C/en not_active Expired - Fee Related
- 2007-06-21 US US12/305,481 patent/US20100204328A1/en not_active Abandoned
- 2007-06-21 PL PL07764759T patent/PL2040689T3/pl unknown
- 2007-06-21 AT AT07764759T patent/ATE489950T1/de not_active IP Right Cessation
- 2007-06-21 WO PCT/EP2007/005466 patent/WO2007147590A2/en not_active Ceased

Also Published As

Publication number	Publication date
DE602007010938D1 (de)	2011-01-13
ES2355853T3 (es)	2011-03-31
CA2655644C (en)	2013-01-08
EP2040689B1 (en)	2010-12-01
CA2655644A1 (en)	2007-12-27
EP2040689A2 (en)	2009-04-01
US20100204328A1 (en)	2010-08-12
WO2007147590A3 (en)	2008-03-13
WO2007147590A2 (en)	2007-12-27
ATE489950T1 (de)	2010-12-15

Publication	Publication Date	Title
NO20091801L (no)	2009-06-30	Peristatisk mikropumpe med utskiftbart pumpehode
FI3698630T3 (fi)	2024-05-24	Typpioksidin annostelu ja seuraaminen ex vivo -nesteissä
WO2010029401A3 (en)	2010-06-10	A procedure and a device for extracorporeal blood treatment using citrate anticoagulation
WO2010098940A3 (en)	2010-11-25	One-way replacement valve
BR112014030611A2 (pt)	2017-06-27	sistema e método de monitoramento e controle de volume de ultrafiltração durante diálise peritoneal usando bioempedância segmentar
WO2008034068A3 (en)	2008-06-26	Intravascular blood pump and catheter
MX2010003871A (es)	2010-04-27	Cateter intravenoso con valvula en linea y metodos relacionados a este.
NZ710157A (en)	2016-08-26	Use of guanethidine for treating hypertension by local vascular delivery
CY1116197T1 (el)	2017-02-08	Διαλυμα εγχυσης και ενεσης της λεβεντοπα
WO2010057262A8 (en)	2010-07-22	Heart valve prosthesis and method
WO2007075545A3 (en)	2008-12-31	Active drainage system for use in defined natural or surgically created body cavities or lumina
MX349383B (es)	2017-07-26	Formulaciones para el tratamiento de diabetes.
WO2009022417A1 (ja)	2009-02-19	腹膜透析液
PL2040689T3 (pl)	2011-04-29	Roztwór zawierający N-acetylocysteinę i kwas glukonowy oraz sposoby redukowania, leczenia i zapobiegania stresowi oksydacyjnemu i aktywacji komórek
DK2175877T3 (da)	2012-04-16	Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme
WO2008120803A1 (ja)	2008-10-09	シリンジポンプを備えた持続的血液浄化装置
EP2106260A4 (en)	2010-05-26	INSULIN SENSITIZERS AND TREATMENT PROCEDURES THEREWITH
TW200740451A (en)	2007-11-01	An agent for rising concentration of Adiponectin
MX2009014178A (es)	2010-06-30	Composicion de microparticulas biocompatibles de acido alginico para la liberacion controlada de principios activos por via intravenosa.
WO2008070353A3 (en)	2008-08-28	Tissue plasminogen activator variant uses
GB2473390A (en)	2011-03-09	Nutritive compositions and methods of using same
WO2007116428A8 (en)	2007-12-13	Oral pharmaceutical composition containing cystine or cysteine with glutathione against oxidative stress resulting from haemodialysis
RU2007103435A (ru)	2008-08-10	Способ патогенетического лечения клещевых нейроинфекций
WO2007112520A3 (fr)	2008-01-03	Dispositif de perfusion veineuse implantable
RU2007127114A (ru)	2009-01-27	Способ снижения концентрации аммиака в крови с помощью аммоцитов и инкапсулированной глутаминсинтетазы