PL2053408T3 - Sposób strukturalnego charakteryzowania rekombinowanego poliklonalnego białka lub poliklonalnej linii komórkowej - Google Patents
Sposób strukturalnego charakteryzowania rekombinowanego poliklonalnego białka lub poliklonalnej linii komórkowejInfo
- Publication number
- PL2053408T3 PL2053408T3 PL09151073T PL09151073T PL2053408T3 PL 2053408 T3 PL2053408 T3 PL 2053408T3 PL 09151073 T PL09151073 T PL 09151073T PL 09151073 T PL09151073 T PL 09151073T PL 2053408 T3 PL2053408 T3 PL 2053408T3
- Authority
- PL
- Poland
- Prior art keywords
- polyclonal
- cell line
- structural characterization
- procedure
- recombinant
- Prior art date
Links
- 238000012512 characterization method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000012252 genetic analysis Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012514 protein characterization Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Document Processing Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401133 | 2004-07-20 | ||
| DKPA200401991 | 2004-12-22 | ||
| EP09151073A EP2053408B1 (en) | 2004-07-20 | 2005-07-20 | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| EP05760790A EP1787126B1 (en) | 2004-07-20 | 2005-07-20 | A procedure for characterization of a polyclonal cell line |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2053408T3 true PL2053408T3 (pl) | 2012-08-31 |
Family
ID=35427551
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09151073T PL2053408T3 (pl) | 2004-07-20 | 2005-07-20 | Sposób strukturalnego charakteryzowania rekombinowanego poliklonalnego białka lub poliklonalnej linii komórkowej |
| PL05760790T PL1787126T3 (pl) | 2004-07-20 | 2005-07-20 | Sposób charakteryzowania poliklonalnej linii komórkowej |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05760790T PL1787126T3 (pl) | 2004-07-20 | 2005-07-20 | Sposób charakteryzowania poliklonalnej linii komórkowej |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8288109B2 (pl) |
| EP (2) | EP2053408B1 (pl) |
| JP (1) | JP4870667B2 (pl) |
| KR (1) | KR101319848B1 (pl) |
| AT (2) | ATE548657T1 (pl) |
| AU (1) | AU2005263334C1 (pl) |
| BR (1) | BRPI0513714A (pl) |
| CA (1) | CA2574146C (pl) |
| DE (1) | DE602005016818D1 (pl) |
| DK (2) | DK1787126T3 (pl) |
| ES (2) | ES2332524T3 (pl) |
| IL (2) | IL180169A (pl) |
| MX (1) | MX2007000551A (pl) |
| NO (1) | NO20070931L (pl) |
| NZ (1) | NZ552264A (pl) |
| PL (2) | PL2053408T3 (pl) |
| RU (1) | RU2426795C2 (pl) |
| WO (1) | WO2006007853A2 (pl) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1583830T1 (sl) * | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| US8288109B2 (en) | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| EA014182B1 (ru) | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| US7850965B2 (en) | 2005-12-05 | 2010-12-14 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| US8338376B2 (en) | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| DK2121920T3 (da) * | 2007-03-01 | 2011-11-21 | Symphogen As | Fremgangsmåde til kloning af sammenhørende antistoffer |
| BRPI0808551B1 (pt) | 2007-03-01 | 2022-04-05 | Symphogen A/S | Composições de anticorpo para o receptor do fator de crescimento antiepidérmico recombinante, molécula de ligação bi-específica e composição farmacêutica que os compreende |
| JP2010534057A (ja) * | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| CA2680792A1 (en) * | 2007-03-15 | 2008-09-18 | Biogen Idec Ma Inc. | Treatment of autoimmune disorders |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| MX2009012526A (es) * | 2007-05-25 | 2009-12-09 | Symphogen As | Metodo para fabricar una proteina policlonal recombinante. |
| CA2695309A1 (en) * | 2007-09-07 | 2009-03-12 | Symphogen A/S | Methods for recombinant manufacturing of anti-rsv antibodies |
| RU2476886C2 (ru) * | 2007-11-22 | 2013-02-27 | Симфоген А/С | Способ характеризации рекомбинантного поликлонального белка |
| NZ588651A (en) * | 2008-04-23 | 2012-04-27 | Symphogen As | Methods for manufacturing a polyclonal protein |
| WO2010022736A2 (en) | 2008-08-29 | 2010-03-04 | Symphogen A/S | Recombinant anti-epidermal growth factor receptor antibody compositions |
| CN102137928A (zh) * | 2008-08-29 | 2011-07-27 | 西福根有限公司 | 克隆禽源抗体的方法 |
| US8821879B2 (en) | 2009-09-04 | 2014-09-02 | Xoma Technology Ltd. | Anti-botulism antibody coformulations |
| MX2012003538A (es) * | 2009-10-09 | 2012-08-03 | Symphogen As | Cuantificacion multiple de proteinas recombinantes individuales en una mezcla mediante peptidos distintivos y espectrometria de masas. |
| US8987419B2 (en) * | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| MX347981B (es) | 2010-11-01 | 2017-05-22 | Symphogen As | Composicion de anticuerpos pan-her. |
| US9790269B2 (en) | 2013-02-08 | 2017-10-17 | Misfolding Diagnostics, Inc. | Transthyretin antibodies and uses thereof |
| US12546782B2 (en) * | 2013-03-15 | 2026-02-10 | Mayo Foundation For Medical Education And Research | Identification and monitoring of monoclonal immunoglobulins related to monoclonal gammopathy by molecular mass with mass spectrometry |
| UY35517A (es) | 2013-04-04 | 2014-10-31 | Mabxience S A | Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína |
| WO2015093925A1 (es) * | 2013-12-19 | 2015-06-25 | CASTRO ALDRETE, Jorge Isaac | Método de producción de anticuerpos específicos |
| TW201623331A (zh) * | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法 |
| WO2018031887A1 (en) * | 2016-08-12 | 2018-02-15 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
| GB201710691D0 (en) * | 2017-07-04 | 2017-08-16 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| EP3810649A1 (en) * | 2018-06-22 | 2021-04-28 | Genmab A/S | Method for producing a controlled mixture of two or more different antibodies |
| CN112816595A (zh) * | 2021-01-06 | 2021-05-18 | 海默斯(重庆)医学生物技术有限公司 | 一种重组角蛋白液体制剂及其纯度检测方法 |
| AU2024323936A1 (en) * | 2023-08-15 | 2026-04-02 | Gigagen, Inc. | Methods of analyzing recombinant polyclonal proteins |
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| WO1985002413A1 (en) | 1983-11-28 | 1985-06-06 | The Board Of Trustees Of The Leland Stanford Jr. U | HUMAN MONOCLONAL ANTIBODY AGAINST Rh(D) ANTIGEN AND ITS USES |
| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| CA1293460C (en) | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
| US5126130A (en) * | 1986-11-24 | 1992-06-30 | The Childrens Hospital Incorporated | Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a |
| GB8722020D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722019D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722018D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| GB8906129D0 (en) | 1989-03-17 | 1989-05-04 | Central Blood Lab Authority | Pharmaceutical preparations |
| GB8919761D0 (en) | 1989-09-01 | 1989-10-18 | Central Blood Lab Authority | Chemical compounds |
| WO1992015694A1 (en) | 1991-03-08 | 1992-09-17 | The Salk Institute For Biological Studies | Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor |
| US5837268A (en) | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
| US5252216A (en) * | 1992-03-24 | 1993-10-12 | Smithkline Beecham Corporation | Protein purification |
| BR9305557A (pt) | 1992-06-26 | 1997-03-25 | Aetsrn | Anticorpos monoclonais humanos anti Rhesus-D e composiçao farmacêutica que os contém |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| DE69534347T2 (de) | 1994-01-31 | 2006-05-24 | Trustees Of Boston University, Boston | Bibliotheken aus Polyklonalen Antikörpern |
| FR2724182B1 (fr) * | 1994-09-02 | 1996-12-13 | Pasteur Institut | Obtention d'un anticorps monoclonal recombinant a partir d'un anticorps monoclonal humain anti-rhesus d, sa production en cellules d'insecte, et ses utilisations |
| US6111166A (en) | 1994-09-19 | 2000-08-29 | Medarex, Incorporated | Transgenic mice expressing human Fcα and β receptors |
| AU722127B2 (en) | 1996-06-24 | 2000-07-20 | Zlb Behring Ag | Polypeptides capable of forming antigen binding structures with specificity for the rhesus D antigens, the DNA encoding them and the process for their preparation and use |
| US6255455B1 (en) * | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
| US5876925A (en) * | 1996-10-11 | 1999-03-02 | The Trustees Of The University Of Pennsylvania | Magnetically activated cell sorting for production of proteins |
| AU737155B2 (en) | 1997-03-14 | 2001-08-09 | Biogen Idec Inc. | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| JPH11174038A (ja) * | 1997-12-10 | 1999-07-02 | Tosoh Corp | 蛋白質の分離精製法 |
| WO2000011155A1 (en) | 1998-08-19 | 2000-03-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for genomic modification |
| US20020155114A1 (en) * | 1998-08-31 | 2002-10-24 | James D. Marks | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
| US6395538B1 (en) * | 1999-07-16 | 2002-05-28 | Human Genome Sciences, Inc. | Method and system for providing real-time, in situ biomanufacturing process monitoring and control in response to IR spectroscopy |
| DK1234022T3 (da) | 1999-07-23 | 2010-07-19 | Univ California | DNA-rekombination i eukaryote celler med bakteriofag PHIC31-rekombinationssystemet |
| EP1106625A1 (en) | 1999-11-17 | 2001-06-13 | ZLB Bioplasma AG | Rhesus D specific peptide sequences |
| CA2401663C (en) | 2000-02-08 | 2008-11-25 | The Regents Of The University Of Michigan | Protein mapping |
| WO2001058925A2 (en) | 2000-02-08 | 2001-08-16 | The Regents Of The University Of Michigan | Protein separation and display |
| US7069151B2 (en) | 2000-02-08 | 2006-06-27 | Regents Of The University Of Michigan | Mapping of differential display of proteins |
| HK1052305B (en) | 2000-05-26 | 2007-10-12 | Symphogen A/S | Recombinant or purified polyclonal antibodies for treating allergy |
| US6610472B1 (en) * | 2000-10-31 | 2003-08-26 | Genetastix Corporation | Assembly and screening of highly complex and fully human antibody repertoire in yeast |
| JP2004514444A (ja) * | 2000-11-28 | 2004-05-20 | アプライド モレキュラー エボリューション, インコーポレイテッド | 二重lox組換えに基づく真核生物発現ライブラリーおよび使用方法 |
| EP1739424B1 (en) * | 2000-12-26 | 2011-08-24 | The Institute for Systems Biology | Rapid and quantitative proteome anaysis and related methods |
| US7541003B2 (en) * | 2001-07-17 | 2009-06-02 | Bio-Rad Laboratories, Inc. | Latex based adsorbent chip |
| WO2003054549A2 (en) * | 2001-12-08 | 2003-07-03 | Micromass Uk Limited | Method of mass spectrometry |
| US20040033591A1 (en) | 2002-05-31 | 2004-02-19 | The Regents Of The University Of Michigan | Automated protein analysis system |
| DK2314629T4 (da) * | 2002-07-18 | 2023-02-06 | Merus Nv | Rekombinant produktion af blandinger af antistoffer |
| JP2004101477A (ja) * | 2002-09-12 | 2004-04-02 | Yoshio Yamauchi | 2次元高速液体クロマトグラフ装置及びそれを用いた蛋白質分析装置 |
| AU2003284227A1 (en) | 2002-10-15 | 2004-05-04 | The Regents Of The University Of Michigan | Multidimensional protein separation system |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| SI1583830T1 (sl) | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| EA014182B1 (ru) | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| US8288109B2 (en) | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| US7850965B2 (en) | 2005-12-05 | 2010-12-14 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| WO2007101441A1 (en) | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| RU2476886C2 (ru) | 2007-11-22 | 2013-02-27 | Симфоген А/С | Способ характеризации рекомбинантного поликлонального белка |
-
2005
- 2005-07-20 US US11/658,021 patent/US8288109B2/en not_active Expired - Fee Related
- 2005-07-20 DE DE602005016818T patent/DE602005016818D1/de not_active Expired - Lifetime
- 2005-07-20 KR KR1020077003954A patent/KR101319848B1/ko not_active Expired - Fee Related
- 2005-07-20 EP EP09151073A patent/EP2053408B1/en not_active Expired - Lifetime
- 2005-07-20 MX MX2007000551A patent/MX2007000551A/es active IP Right Grant
- 2005-07-20 AT AT09151073T patent/ATE548657T1/de active
- 2005-07-20 AU AU2005263334A patent/AU2005263334C1/en not_active Ceased
- 2005-07-20 JP JP2007521795A patent/JP4870667B2/ja not_active Expired - Fee Related
- 2005-07-20 DK DK05760790T patent/DK1787126T3/da active
- 2005-07-20 ES ES05760790T patent/ES2332524T3/es not_active Expired - Lifetime
- 2005-07-20 AT AT05760790T patent/ATE443870T1/de active
- 2005-07-20 WO PCT/DK2005/000504 patent/WO2006007853A2/en not_active Ceased
- 2005-07-20 RU RU2007106050/10A patent/RU2426795C2/ru not_active IP Right Cessation
- 2005-07-20 ES ES09151073T patent/ES2381531T3/es not_active Expired - Lifetime
- 2005-07-20 EP EP05760790A patent/EP1787126B1/en not_active Expired - Lifetime
- 2005-07-20 BR BRPI0513714-4A patent/BRPI0513714A/pt not_active Application Discontinuation
- 2005-07-20 DK DK09151073.5T patent/DK2053408T3/da active
- 2005-07-20 PL PL09151073T patent/PL2053408T3/pl unknown
- 2005-07-20 NZ NZ552264A patent/NZ552264A/en not_active IP Right Cessation
- 2005-07-20 PL PL05760790T patent/PL1787126T3/pl unknown
- 2005-07-20 CA CA2574146A patent/CA2574146C/en not_active Expired - Fee Related
-
2006
- 2006-12-19 IL IL180169A patent/IL180169A/en not_active IP Right Cessation
-
2007
- 2007-02-19 NO NO20070931A patent/NO20070931L/no not_active Application Discontinuation
-
2009
- 2009-12-29 IL IL203017A patent/IL203017A/en not_active IP Right Cessation
-
2012
- 2012-10-16 US US13/653,316 patent/US9029091B2/en not_active Expired - Fee Related
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