PL2070946T3 - Wynalazek dotyczący GLP-1 i eksendyny - Google Patents

Wynalazek dotyczący GLP-1 i eksendyny

Info

Publication number
PL2070946T3
PL2070946T3 PL08020703T PL08020703T PL2070946T3 PL 2070946 T3 PL2070946 T3 PL 2070946T3 PL 08020703 T PL08020703 T PL 08020703T PL 08020703 T PL08020703 T PL 08020703T PL 2070946 T3 PL2070946 T3 PL 2070946T3
Authority
PL
Poland
Prior art keywords
glu
ser
gly
leu
ala
Prior art date
Application number
PL08020703T
Other languages
English (en)
Inventor
Martin Béhé
Martin Gotthardt
Thomas Behr
Burkhard J Göke
Original Assignee
Philipps Univ Marburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philipps Univ Marburg filed Critical Philipps Univ Marburg
Publication of PL2070946T3 publication Critical patent/PL2070946T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
PL08020703T 2004-09-03 2005-08-26 Wynalazek dotyczący GLP-1 i eksendyny PL2070946T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004043153A DE102004043153B4 (de) 2004-09-03 2004-09-03 Erfindung betreffend GLP-1 und Exendin
EP08020703.8A EP2070946B1 (de) 2004-09-03 2005-08-26 Erfindung betreffend GLP-1 und Exendin
EP05778889A EP1784422B1 (de) 2004-09-03 2005-08-26 Erfindung betreffend glp-1 und exendin

Publications (1)

Publication Number Publication Date
PL2070946T3 true PL2070946T3 (pl) 2013-09-30

Family

ID=35970651

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10012756T PL2301962T3 (pl) 2004-09-03 2005-08-26 Wynalazek dotyczący glp-1 i eksendyny
PL08020703T PL2070946T3 (pl) 2004-09-03 2005-08-26 Wynalazek dotyczący GLP-1 i eksendyny

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL10012756T PL2301962T3 (pl) 2004-09-03 2005-08-26 Wynalazek dotyczący glp-1 i eksendyny

Country Status (16)

Country Link
US (2) US8268781B2 (pl)
EP (3) EP2070946B1 (pl)
JP (1) JP5047795B2 (pl)
KR (1) KR101237152B1 (pl)
CN (3) CN102358752B (pl)
AT (1) ATE486090T1 (pl)
AU (1) AU2005279537C1 (pl)
BR (1) BRPI0515624A (pl)
CA (2) CA2578252A1 (pl)
DE (2) DE102004043153B4 (pl)
HR (1) HRP20110061T1 (pl)
MX (1) MX2007002455A (pl)
NO (1) NO20071592L (pl)
PL (2) PL2301962T3 (pl)
RU (3) RU2489443C2 (pl)
WO (1) WO2006024275A2 (pl)

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EP3228320B1 (de) 2008-10-17 2019-12-18 Sanofi-Aventis Deutschland GmbH Kombination von einem insulin und einem glp-1-agonisten
US8992886B2 (en) 2009-04-06 2015-03-31 Board Of Regents, The University Of Texas System Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells
JP5685401B2 (ja) * 2009-08-10 2015-03-18 国立大学法人京都大学 膵島イメージング用分子プローブ及びその前駆体、並びに、それらの使用
WO2011027584A1 (ja) * 2009-09-04 2011-03-10 国立大学法人京都大学 膵島イメージング用分子プローブ及びその使用
JP5608867B2 (ja) * 2009-09-30 2014-10-15 国立大学法人京都大学 膵島イメージング用分子プローブ及びその使用
PT2554183T (pt) 2009-11-13 2018-07-09 Sanofi Aventis Deutschland Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina
PE20121316A1 (es) 2009-11-13 2012-10-05 Sanofi Aventis Deutschland Composicion farmaceutica que comprende un agonista de glp-1 y metionina
EP2510951B1 (en) 2009-12-10 2016-07-13 Kyoto University Molecular probe for imaging of pancreatic islet, and use thereof
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US20140148384A1 (en) 2010-08-30 2014-05-29 Sanofi-Aventis Deutschland Gmbh Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9278146B2 (en) 2010-10-08 2016-03-08 Kyoto University Peptide derivative and use of the same
US9289516B2 (en) 2011-03-09 2016-03-22 The General Hospital Corporation Imaging beta cell mass
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9944687B2 (en) 2011-07-04 2018-04-17 Imperial Innovations Limited Compounds and their effects on feeding behaviour
CN108079281A (zh) 2011-08-29 2018-05-29 赛诺菲-安万特德国有限公司 用于2型糖尿病患者中的血糖控制的药物组合
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
US8901484B2 (en) * 2012-04-27 2014-12-02 Sanofi-Aventis Deutschland Gmbh Quantification of impurities for release testing of peptide products
WO2013182217A1 (en) * 2012-04-27 2013-12-12 Sanofi-Aventis Deutschland Gmbh Quantification of impurities for release testing of peptide products
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SG10201705097PA (en) 2012-12-21 2017-07-28 Sanofi Sa Functionalized exendin-4 derivatives
CN103344764B (zh) * 2013-06-19 2014-11-26 天津美德太平洋科技有限公司 胰高血糖素样肽-1生物学活性检测试剂及检测方法和试剂盒
EP3080149A1 (en) 2013-12-13 2016-10-19 Sanofi Dual glp-1/glucagon receptor agonists
WO2015086729A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/gip receptor agonists
TW201609795A (zh) 2013-12-13 2016-03-16 賽諾菲公司 作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
WO2015086730A1 (en) 2013-12-13 2015-06-18 Sanofi Non-acylated exendin-4 peptide analogues
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
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Also Published As

Publication number Publication date
CA2797666A1 (en) 2006-03-09
KR20070093960A (ko) 2007-09-19
DE102004043153B4 (de) 2013-11-21
HRP20110061T1 (hr) 2011-02-28
BRPI0515624A (pt) 2008-07-29
AU2005279537B2 (en) 2012-02-16
CN101010340A (zh) 2007-08-01
EP2301962A3 (de) 2011-11-02
DE502005010449D1 (de) 2010-12-09
CN101010340B (zh) 2012-11-28
JP5047795B2 (ja) 2012-10-10
CA2578252A1 (en) 2006-03-09
JP2008511557A (ja) 2008-04-17
KR101237152B1 (ko) 2013-03-04
EP2301962B1 (de) 2013-10-30
RU2489443C2 (ru) 2013-08-10
PL2301962T3 (pl) 2014-05-30
RU2420536C2 (ru) 2011-06-10
RU2010148447A (ru) 2012-06-10
WO2006024275A2 (de) 2006-03-09
AU2005279537C1 (en) 2012-07-05
MX2007002455A (es) 2007-10-10
RU2486197C2 (ru) 2013-06-27
CN102304179A (zh) 2012-01-04
US20090180953A1 (en) 2009-07-16
EP2070946A2 (de) 2009-06-17
RU2007112115A (ru) 2008-10-10
CN102358752A (zh) 2012-02-22
EP1784422A2 (de) 2007-05-16
EP2070946B1 (de) 2013-05-29
WO2006024275A3 (de) 2006-11-30
US20130095037A1 (en) 2013-04-18
DE102004043153A1 (de) 2006-03-23
CN102358752B (zh) 2014-07-30
AU2005279537A1 (en) 2006-03-09
EP1784422B1 (de) 2010-10-27
ATE486090T1 (de) 2010-11-15
US8268781B2 (en) 2012-09-18
RU2010148446A (ru) 2012-06-10
NO20071592L (no) 2007-05-29
EP2301962A2 (de) 2011-03-30
EP2070946A3 (de) 2009-09-09

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