PL2089364T3 - Związki pirydynonu - Google Patents

Związki pirydynonu

Info

Publication number
PL2089364T3
PL2089364T3 PL07844974T PL07844974T PL2089364T3 PL 2089364 T3 PL2089364 T3 PL 2089364T3 PL 07844974 T PL07844974 T PL 07844974T PL 07844974 T PL07844974 T PL 07844974T PL 2089364 T3 PL2089364 T3 PL 2089364T3
Authority
PL
Poland
Prior art keywords
pyridinone compounds
pyridinone
compounds
Prior art date
Application number
PL07844974T
Other languages
English (en)
Inventor
Robert M Borzilleri
Gretchen M Schroeder
Zhen-Wei Cai
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PL2089364T3 publication Critical patent/PL2089364T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
PL07844974T 2006-11-08 2007-11-08 Związki pirydynonu PL2089364T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85754006P 2006-11-08 2006-11-08
PCT/US2007/084047 WO2008058229A1 (en) 2006-11-08 2007-11-08 Pyridinone compounds
EP07844974.1A EP2089364B1 (en) 2006-11-08 2007-11-08 Pyridinone compounds

Publications (1)

Publication Number Publication Date
PL2089364T3 true PL2089364T3 (pl) 2013-11-29

Family

ID=39048786

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07844974T PL2089364T3 (pl) 2006-11-08 2007-11-08 Związki pirydynonu

Country Status (20)

Country Link
US (2) US7851489B2 (pl)
EP (1) EP2089364B1 (pl)
JP (1) JP5276005B2 (pl)
KR (1) KR101390076B1 (pl)
CN (1) CN101535264B (pl)
AR (1) AR063628A1 (pl)
AU (1) AU2007317296B2 (pl)
CA (1) CA2669266C (pl)
CL (1) CL2007003226A1 (pl)
DK (1) DK2089364T3 (pl)
ES (1) ES2424851T3 (pl)
HR (1) HRP20130626T1 (pl)
MX (1) MX2009004699A (pl)
NO (1) NO342395B1 (pl)
PE (1) PE20081490A1 (pl)
PL (1) PL2089364T3 (pl)
PT (1) PT2089364E (pl)
SI (1) SI2089364T1 (pl)
TW (1) TWI409259B (pl)
WO (1) WO2008058229A1 (pl)

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WO2019083458A1 (en) 2017-10-25 2019-05-02 Aslan Pharmaceuticals Pte Ltd VARLITINIB FOR THE TREATMENT OF CANCER TO REDUCE HYPOXIA
WO2019083457A1 (en) 2017-10-25 2019-05-02 Aslan Pharmaceuticals Pte Ltd VARLITINIB FOR USE IN THE TREATMENT OF CANCER IN A PATIENT IDENTIFIED AS MUTATION OF THE BETA-CATENIN PATHWAY
JP7377798B2 (ja) * 2017-11-24 2023-11-10 南京明徳新薬研発有限公司 c-MET/AXL阻害剤としてのウラシル系化合物
ES2980476T3 (es) 2018-03-08 2024-10-01 Wellmarker Bio Co Ltd Derivados de tienopiridina y composición farmacéutica que los contiene
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MD3790877T2 (ro) 2018-05-11 2023-08-31 Incyte Corp Derivați de tetrahidro-imidazo[4,5-c]piridină în calitate de imunomodulatori PD-L1
KR20210090625A (ko) 2018-10-09 2021-07-20 아슬란 파마슈티컬스 피티이 엘티디 바를리티닙의 말론산 염
JP2022505272A (ja) * 2018-10-19 2022-01-14 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア がん治療のためのトポイソメラーゼii触媒阻害剤化合物による治療、方法、及び使用
WO2020150307A1 (en) * 2019-01-15 2020-07-23 The Translational Genomics Research Institute Phosphonate conjugates and uses thereof
KR20210015730A (ko) * 2019-08-02 2021-02-10 웰마커바이오 주식회사 옥소-피리딘 융합고리 유도체 및 이를 포함하는 약학적 조성물
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Also Published As

Publication number Publication date
KR101390076B1 (ko) 2014-04-29
CA2669266C (en) 2014-04-29
AU2007317296B2 (en) 2012-07-05
PE20081490A1 (es) 2008-10-30
WO2008058229A1 (en) 2008-05-15
US7851489B2 (en) 2010-12-14
ES2424851T3 (es) 2013-10-09
CA2669266A1 (en) 2008-05-15
US8536200B2 (en) 2013-09-17
TWI409259B (zh) 2013-09-21
US20110052583A1 (en) 2011-03-03
NO20091605L (no) 2009-05-27
JP5276005B2 (ja) 2013-08-28
CL2007003226A1 (es) 2008-02-08
HK1131608A1 (en) 2010-01-29
PT2089364E (pt) 2013-08-26
EP2089364A1 (en) 2009-08-19
CN101535264A (zh) 2009-09-16
US20080114033A1 (en) 2008-05-15
CN101535264B (zh) 2012-11-28
TW200829564A (en) 2008-07-16
JP2010509362A (ja) 2010-03-25
HRP20130626T1 (en) 2013-08-31
KR20090096423A (ko) 2009-09-10
MX2009004699A (es) 2009-05-15
SI2089364T1 (sl) 2013-10-30
EP2089364B1 (en) 2013-06-12
AU2007317296A1 (en) 2008-05-15
DK2089364T3 (da) 2013-09-02
NO342395B1 (no) 2018-05-14
AR063628A1 (es) 2009-02-04

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