PL2089364T3 - Związki pirydynonu - Google Patents
Związki pirydynonuInfo
- Publication number
- PL2089364T3 PL2089364T3 PL07844974T PL07844974T PL2089364T3 PL 2089364 T3 PL2089364 T3 PL 2089364T3 PL 07844974 T PL07844974 T PL 07844974T PL 07844974 T PL07844974 T PL 07844974T PL 2089364 T3 PL2089364 T3 PL 2089364T3
- Authority
- PL
- Poland
- Prior art keywords
- pyridinone compounds
- pyridinone
- compounds
- Prior art date
Links
- 150000005299 pyridinones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85754006P | 2006-11-08 | 2006-11-08 | |
| EP07844974.1A EP2089364B1 (en) | 2006-11-08 | 2007-11-08 | Pyridinone compounds |
| PCT/US2007/084047 WO2008058229A1 (en) | 2006-11-08 | 2007-11-08 | Pyridinone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2089364T3 true PL2089364T3 (pl) | 2013-11-29 |
Family
ID=39048786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07844974T PL2089364T3 (pl) | 2006-11-08 | 2007-11-08 | Związki pirydynonu |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7851489B2 (pl) |
| EP (1) | EP2089364B1 (pl) |
| JP (1) | JP5276005B2 (pl) |
| KR (1) | KR101390076B1 (pl) |
| CN (1) | CN101535264B (pl) |
| AR (1) | AR063628A1 (pl) |
| AU (1) | AU2007317296B2 (pl) |
| CA (1) | CA2669266C (pl) |
| CL (1) | CL2007003226A1 (pl) |
| DK (1) | DK2089364T3 (pl) |
| ES (1) | ES2424851T3 (pl) |
| HR (1) | HRP20130626T1 (pl) |
| MX (1) | MX2009004699A (pl) |
| NO (1) | NO342395B1 (pl) |
| PE (1) | PE20081490A1 (pl) |
| PL (1) | PL2089364T3 (pl) |
| PT (1) | PT2089364E (pl) |
| SI (1) | SI2089364T1 (pl) |
| TW (1) | TWI409259B (pl) |
| WO (1) | WO2008058229A1 (pl) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5693239B2 (ja) * | 2008-01-23 | 2015-04-01 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ４−ピリジノン化合物および癌についてのその使用 |
| CN102099036B (zh) | 2008-06-03 | 2015-05-27 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
| CA2800998A1 (en) | 2010-04-29 | 2011-11-10 | Deciphera Pharmaceuticals, Llc | Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activities |
| SG184891A1 (en) | 2010-04-30 | 2012-11-29 | Bristol Myers Squibb Co | Pharmaceutical compositions comprising n-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-l-(4-fluorophenyl)-2-oxo- 1,2-dihydropyridine-3 -carboxamide |
| CN102241625B (zh) * | 2010-05-13 | 2014-10-29 | 中南大学 | 1-(取代芳基)-5-((取代芳胺基)甲基)吡啶-2(1h)酮化合物、制备方法及其用途 |
| CN102070518B (zh) * | 2011-01-24 | 2012-05-02 | 江苏先声药物研究有限公司 | 取代吡啶及氮杂吲哚衍生物的合成 |
| MX354412B (es) | 2011-06-10 | 2018-03-05 | Merck Patent Gmbh | Composiciones y metodos para la produccion de compuestos de pirimidina con actividad inhibidora de tirosina cinasa de bruton. |
| JP2015507606A (ja) * | 2011-11-22 | 2015-03-12 | デシフェラ ファーマシューティカルズ，エルエルシー | 抗癌および抗増殖作用を示すピリドンアミドおよび類似体 |
| US8975282B2 (en) | 2012-07-28 | 2015-03-10 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrazolone compounds and methods of use |
| JP6342392B2 (ja) | 2012-07-28 | 2018-06-13 | カリター・サイエンシーズ・エルエルシー | 置換型ピラゾロン化合物及び使用方法 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
| WO2017070089A1 (en) | 2015-10-19 | 2017-04-27 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| SG10202004618TA (en) | 2015-11-19 | 2020-06-29 | Incyte Corp | Heterocyclic compounds as immunomodulators |
| MA44075A (fr) | 2015-12-17 | 2021-05-19 | Incyte Corp | Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1 |
| AU2016379372A1 (en) | 2015-12-22 | 2018-08-02 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| AR108396A1 (es) | 2016-05-06 | 2018-08-15 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
| WO2017205464A1 (en) | 2016-05-26 | 2017-11-30 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| HUE060256T2 (hu) | 2016-06-20 | 2023-02-28 | Incyte Corp | Heterociklusos vegyületek mint immunmodulátorok |
| EP3484866B1 (en) * | 2016-07-14 | 2022-09-07 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| WO2018044783A1 (en) | 2016-08-29 | 2018-03-08 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| US10633341B2 (en) * | 2016-12-19 | 2020-04-28 | Novartis Ag | Picolinic acid derivatives and their use as intermediates |
| JP7101678B2 (ja) | 2016-12-22 | 2022-07-15 | インサイト・コーポレイション | 免疫調節剤としての複素環式化合物 |
| ES2874756T3 (es) | 2016-12-22 | 2021-11-05 | Incyte Corp | Derivados de triazolo[1,5-A]piridina como inmunomoduladores |
| US20180179202A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| WO2018136009A1 (en) | 2017-01-20 | 2018-07-26 | Aslan Pharmaceuticals Pte Ltd | Combination therapy |
| WO2018136010A1 (en) | 2017-01-20 | 2018-07-26 | Aslan Pharmaceuticals Pte Ltd | Combination therapy |
| TW201834649A (zh) | 2017-03-02 | 2018-10-01 | 新加坡商亞獅康私人有限公司 | 癌症療法 |
| CN108623568B (zh) * | 2017-03-21 | 2022-04-19 | 南京汇诚制药有限公司 | 9,10二氢菲类丙型肝炎病毒抑制剂的盐型及其制备 |
| WO2018222135A1 (en) | 2017-06-02 | 2018-12-06 | Aslan Pharmaceuticals Pte Ltd | Cancer therapy |
| WO2018222134A1 (en) | 2017-06-02 | 2018-12-06 | Aslan Pharmaceuticals Pte Ltd | Cancer therapy |
| WO2019083455A1 (en) | 2017-10-25 | 2019-05-02 | Aslan Pharmaceuticals Pte Ltd | VARLITINIB FOR USE IN THE TREATMENT OF CANCER IN A PATIENT IDENTIFIED AS PRESENTING HER1, HER2 AND / OR HER3-ACTIVATED HERC-RECEPTOR CANCER CELLS |
| WO2019083456A1 (en) | 2017-10-25 | 2019-05-02 | Aslan Pharmaceuticals Pte Ltd | VARLITINIB FOR USE IN THE TREATMENT OF CANCER FOR NORMALIZING ANGIOGENESIS IN A CANCER MASS |
| WO2019083458A1 (en) | 2017-10-25 | 2019-05-02 | Aslan Pharmaceuticals Pte Ltd | VARLITINIB FOR THE TREATMENT OF CANCER TO REDUCE HYPOXIA |
| WO2019083457A1 (en) | 2017-10-25 | 2019-05-02 | Aslan Pharmaceuticals Pte Ltd | VARLITINIB FOR USE IN THE TREATMENT OF CANCER IN A PATIENT IDENTIFIED AS MUTATION OF THE BETA-CATENIN PATHWAY |
| US11623923B2 (en) * | 2017-11-24 | 2023-04-11 | Medshine Discovery, Inc. | Uracil compound as c-MET/AXL inhibitor |
| WO2019182274A1 (en) | 2018-03-08 | 2019-09-26 | Wellmarker Bio Co., Ltd. | Thienopyridine derivatives and pharmaceutical composition comprising same |
| SMT202500157T1 (it) | 2018-03-30 | 2025-05-12 | Incyte Corp | Composti eterociclici come immunomodulatori |
| HUE061503T2 (hu) | 2018-05-11 | 2023-07-28 | Incyte Corp | Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok |
| JP2022504201A (ja) | 2018-10-09 | 2022-01-13 | アスラン ファーマシューティカルズ ピーティーイー リミテッド | バリチニブのマロン酸塩 |
| JP2022505272A (ja) * | 2018-10-19 | 2022-01-14 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | がん治療のためのトポイソメラーゼｉｉ触媒阻害剤化合物による治療、方法、及び使用 |
| US12595273B2 (en) | 2019-01-15 | 2026-04-07 | The Translational Genomics Research Institute | Phosphonate conjugates and uses thereof |
| US20220235064A1 (en) * | 2019-08-02 | 2022-07-28 | Wellmarker Bio Co., Ltd. | Oxo-pyridine fusion ring derivative and pharmaceutical composition comprising same |
| JP7665593B2 (ja) | 2019-08-09 | 2025-04-21 | インサイト・コーポレイション | Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩 |
| EP3819300A4 (en) | 2019-09-06 | 2021-11-24 | Wellmarker Bio Co., Ltd. | THERAPEUTIC COMPOSITION BASED ON BIOMARKERS |
| PE20221038A1 (es) | 2019-09-30 | 2022-06-17 | Incyte Corp | Compuestos de pirido[3,2-d] pirimidina como inmunomoduladores |
| CA3160131A1 (en) | 2019-11-11 | 2021-05-20 | Incyte Corporation | Salts and crystalline forms of a pd-1/pd-l1 inhibitor |
| JP2023513675A (ja) | 2020-02-06 | 2023-04-03 | ウェルマーカー・バイオ・カンパニー・リミテッド | Ｋｒａｓ変異に関連する癌の予防または治療のための医薬組成物 |
| KR20210111711A (ko) | 2020-03-03 | 2021-09-13 | 웰마커바이오 주식회사 | Kras 돌연변이 및 활성화된 ron이 존재하는 암의 예방 또는 치료용 약학 조성물 |
| US20230202992A1 (en) | 2020-05-18 | 2023-06-29 | Wellmarker Bio Co., Ltd. | Pharmaceutical composition for preventing or treating small-cell lung cancer associated with ron mutants and method using same |
| KR20210142555A (ko) | 2020-05-18 | 2021-11-25 | 웰마커바이오 주식회사 | Ron 돌연변이와 관련된 췌장암 예방 또는 치료용 약학 조성물 및 이를 이용한 방법 |
| JP2023526443A (ja) | 2020-05-18 | 2023-06-21 | ウェルマーカー バイオ カンパニー リミテッド | Ｒｏｎ変異が関与する非小細胞肺がんの予防又は治療用医薬組成物及びその使用方法 |
| TW202233615A (zh) | 2020-11-06 | 2022-09-01 | 美商英塞特公司 | Ｐｄ—１／ｐｄ—ｌ１抑制劑之結晶形式 |
| CR20230230A (es) | 2020-11-06 | 2023-07-27 | Incyte Corp | Proceso para hacer un inhibidor de pd-1/pdl1 y sales y formas cristalinas del mismo |
| WO2022099018A1 (en) | 2020-11-06 | 2022-05-12 | Incyte Corporation | Process of preparing a pd-1/pd-l1 inhibitor |
| WO2022169248A1 (ko) * | 2021-02-02 | 2022-08-11 | 주식회사 엘지화학 | 단백질 키나아제 억제제로서의 신규한 화합물 |
| KR20220170766A (ko) * | 2021-06-22 | 2022-12-30 | 주식회사 엘지화학 | 단백질 키나아제 억제제로서의 신규한 화합물 |
| US20230257364A1 (en) * | 2022-02-16 | 2023-08-17 | Cmg Pharmaceutical Co., Ltd. | Pyridazinone-based compounds as axl, c-met, and mer inhibitors and methods of use thereof |
| KR20240101434A (ko) * | 2022-12-23 | 2024-07-02 | 주식회사 엘지화학 | Ron 억제제로서 신규한 화합물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0430885A3 (en) | 1989-12-01 | 1991-11-06 | Ciba-Geigy Ag | Anthelmintical compounds |
| EP0860433B1 (en) | 1995-11-07 | 2002-07-03 | Kirin Beer Kabushiki Kaisha | Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same |
| CA2333554A1 (en) | 1998-06-17 | 1999-12-23 | Chu-Baio Xue | Cyclic hydroxamic acids as metalloproteinase inhibitors |
| ES2546386T3 (es) | 1999-07-20 | 2015-09-23 | Dow Agrosciences, Llc | Amidas aromáticas heterocíclicas fungicidas y sus composiciones, métodos de uso y preparación |
| US6355660B1 (en) | 1999-07-20 | 2002-03-12 | Dow Agrosciences Llc | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
| CA2384291A1 (en) | 1999-09-21 | 2001-03-29 | Astrazeneca Ab | Quinazoline derivatives and their use as pharmaceuticals |
| FR2812633A1 (fr) | 2000-08-04 | 2002-02-08 | Aventis Cropscience Sa | Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides |
| SE0102384D0 (sv) | 2001-07-03 | 2001-07-03 | Pharmacia Ab | New compounds |
| US20050038035A1 (en) | 2001-11-28 | 2005-02-17 | Hisashi Takasugi | Heterocyclic amide compounds as apolipoprotein b inhibitors |
| SE0302487D0 (sv) | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| JP4829506B2 (ja) | 2004-02-17 | 2011-12-07 | 石原産業株式会社 | チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤 |
| US7459562B2 (en) * | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| CA2564355C (en) | 2004-05-07 | 2012-07-03 | Amgen Inc. | Protein kinase modulators and method of use |
| US7432373B2 (en) | 2004-06-28 | 2008-10-07 | Bristol-Meyers Squibb Company | Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors |
| US7439246B2 (en) | 2004-06-28 | 2008-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic kinase inhibitors |
| US7173031B2 (en) | 2004-06-28 | 2007-02-06 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| WO2007033196A1 (en) | 2005-09-14 | 2007-03-22 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US7880004B2 (en) | 2005-09-15 | 2011-02-01 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US7348325B2 (en) | 2005-11-30 | 2008-03-25 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
-
2007
- 2007-11-08 SI SI200731303T patent/SI2089364T1/sl unknown
- 2007-11-08 ES ES07844974T patent/ES2424851T3/es active Active
- 2007-11-08 EP EP07844974.1A patent/EP2089364B1/en active Active
- 2007-11-08 TW TW096142253A patent/TWI409259B/zh active
- 2007-11-08 AU AU2007317296A patent/AU2007317296B2/en active Active
- 2007-11-08 PE PE2007001538A patent/PE20081490A1/es active IP Right Grant
- 2007-11-08 PT PT78449741T patent/PT2089364E/pt unknown
- 2007-11-08 PL PL07844974T patent/PL2089364T3/pl unknown
- 2007-11-08 AR ARP070104987A patent/AR063628A1/es unknown
- 2007-11-08 CA CA2669266A patent/CA2669266C/en active Active
- 2007-11-08 MX MX2009004699A patent/MX2009004699A/es active IP Right Grant
- 2007-11-08 KR KR1020097009449A patent/KR101390076B1/ko active Active
- 2007-11-08 DK DK07844974.1T patent/DK2089364T3/da active
- 2007-11-08 HR HRP20130626TT patent/HRP20130626T1/hr unknown
- 2007-11-08 JP JP2009536476A patent/JP5276005B2/ja active Active
- 2007-11-08 WO PCT/US2007/084047 patent/WO2008058229A1/en not_active Ceased
- 2007-11-08 CN CN2007800414202A patent/CN101535264B/zh active Active
- 2007-11-08 CL CL200703226A patent/CL2007003226A1/es unknown
- 2007-11-08 US US11/936,984 patent/US7851489B2/en active Active
-
2009
- 2009-04-22 NO NO20091605A patent/NO342395B1/no unknown
-
2010
- 2010-11-08 US US12/941,419 patent/US8536200B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SI2089364T1 (sl) | 2013-10-30 |
| NO342395B1 (no) | 2018-05-14 |
| PT2089364E (pt) | 2013-08-26 |
| JP2010509362A (ja) | 2010-03-25 |
| AR063628A1 (es) | 2009-02-04 |
| AU2007317296A1 (en) | 2008-05-15 |
| CA2669266C (en) | 2014-04-29 |
| CL2007003226A1 (es) | 2008-02-08 |
| HK1131608A1 (en) | 2010-01-29 |
| JP5276005B2 (ja) | 2013-08-28 |
| CN101535264B (zh) | 2012-11-28 |
| ES2424851T3 (es) | 2013-10-09 |
| EP2089364B1 (en) | 2013-06-12 |
| CA2669266A1 (en) | 2008-05-15 |
| DK2089364T3 (da) | 2013-09-02 |
| US8536200B2 (en) | 2013-09-17 |
| CN101535264A (zh) | 2009-09-16 |
| KR20090096423A (ko) | 2009-09-10 |
| PE20081490A1 (es) | 2008-10-30 |
| KR101390076B1 (ko) | 2014-04-29 |
| HRP20130626T1 (en) | 2013-08-31 |
| NO20091605L (no) | 2009-05-27 |
| EP2089364A1 (en) | 2009-08-19 |
| MX2009004699A (es) | 2009-05-15 |
| WO2008058229A1 (en) | 2008-05-15 |
| US7851489B2 (en) | 2010-12-14 |
| US20080114033A1 (en) | 2008-05-15 |
| US20110052583A1 (en) | 2011-03-03 |
| TW200829564A (en) | 2008-07-16 |
| TWI409259B (zh) | 2013-09-21 |
| AU2007317296B2 (en) | 2012-07-05 |
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| GB0605784D0 (en) | Compounds | |
| GB0606913D0 (en) | Compounds | |
| GB0602042D0 (en) | Compounds | |
| AP2009004767A0 (en) | Cubstituted azolin-2-yl-amino compounds | |
| EP1973905A4 (en) | COMPOUNDS | |
| GB0600427D0 (en) | Compounds | |
| GB0607839D0 (en) | Compounds | |
| GB0603133D0 (en) | Compounds | |
| GB0602040D0 (en) | Compounds | |
| GB0607978D0 (en) | Compounds | |
| GB0605588D0 (en) | Compounds | |
| GB0605589D0 (en) | Compounds | |
| GB0607409D0 (en) | Npvel compounds | |
| GB0604377D0 (en) | Compounds |