PL2187741T3 - Nowe postacie estru metylowego cddo - Google Patents

Nowe postacie estru metylowego cddo

Info

Publication number: PL2187741T3
Authority: PL; Poland
Prior art keywords: methyl ester; novel forms; cddo methyl; cddo; novel
Prior art date: 2007-08-15

Application number

PL08795303T

Other languages

English (en)

Inventor

John Walling

Stephan D Parent

David T Jonaitis

Robert M Kral

Original Assignee

Reata Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-15

Filing date

2008-08-14

Publication date

2012-08-31

2008-08-14 Application filed by Reata Pharmaceuticals Inc filed Critical Reata Pharmaceuticals Inc

2012-08-31 Publication of PL2187741T3 publication Critical patent/PL2187741T3/pl

Links

WPTTVJLTNAWYAO-KPOXMGGZSA-N Bardoxolone methyl Chemical compound C([C@@]12C)=C(C#N)C(=O)C(C)(C)[C@@H]1CC[C@]1(C)C2=CC(=O)[C@@H]2[C@@H]3CC(C)(C)CC[C@]3(C(=O)OC)CC[C@]21C WPTTVJLTNAWYAO-KPOXMGGZSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Glass Compositions (AREA)

PL08795303T 2007-08-15 2008-08-14 Nowe postacie estru metylowego cddo PL2187741T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US95593907P	2007-08-15	2007-08-15
EP08795303A EP2187741B1 (en)	2007-08-15	2008-08-14	Novel forms of cddo methyl ester
PCT/US2008/009703 WO2009023232A1 (en)	2007-08-15	2008-08-14	Novel forms of cddo methyl ester

Publications (1)

Publication Number	Publication Date
PL2187741T3 true PL2187741T3 (pl)	2012-08-31

Family

ID=40351005

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL08795303T PL2187741T3 (pl)	2007-08-15	2008-08-14	Nowe postacie estru metylowego cddo
PL12153605T PL2450057T3 (pl)	2007-08-15	2008-08-14	Nowe postacie estru metylowego CDDO

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL12153605T PL2450057T3 (pl)	2007-08-15	2008-08-14	Nowe postacie estru metylowego CDDO

Country Status (28)

Country	Link
US (3)	US8088824B2 (pl)
EP (2)	EP2450057B1 (pl)
JP (4)	JP5005812B2 (pl)
KR (2)	KR101481764B1 (pl)
CN (2)	CN101820758B (pl)
AR (2)	AR073155A1 (pl)
AT (1)	ATE549035T1 (pl)
AU (1)	AU2008287388B2 (pl)
BR (1)	BRPI0815540A8 (pl)
CA (2)	CA2871864C (pl)
CL (1)	CL2008002417A1 (pl)
CY (2)	CY1112864T1 (pl)
DK (2)	DK2450057T3 (pl)
EA (2)	EA018704B1 (pl)
ES (2)	ES2382571T3 (pl)
HR (2)	HRP20120350T1 (pl)
HU (1)	HUE031866T2 (pl)
IL (2)	IL203824A (pl)
LT (1)	LT2450057T (pl)
MX (1)	MX2010001628A (pl)
NZ (1)	NZ583269A (pl)
PL (2)	PL2187741T3 (pl)
PT (2)	PT2187741E (pl)
SG (2)	SG10201504650VA (pl)
SI (2)	SI2187741T1 (pl)
TW (2)	TWI486357B (pl)
WO (1)	WO2009023232A1 (pl)
ZA (1)	ZA201001066B (pl)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6326507B1 (en)	1998-06-19	2001-12-04	Trustees Of Dartmouth College	Therapeutic compounds and methods of use
US7435755B2 (en)	2000-11-28	2008-10-14	The Trustees Of Dartmouth College	CDDO-compounds and combination therapies thereof
US7176237B2 (en)	2002-01-15	2007-02-13	The Trustees Of Dartmouth College	Tricyclic-bis-enone derivatives and methods of use thereof
EP2094651A1 (en)	2006-11-17	2009-09-02	Trustees Of Dartmouth College	Synthesis and biological activities of new tricyclic-bis-enones (tbes)
US8299046B2 (en)	2006-11-17	2012-10-30	Trustees Of Dartmouth College	Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth
US8921340B2 (en)	2006-11-17	2014-12-30	Trustees Of Dartmouth College	Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions
US8088824B2 (en) *	2007-08-15	2012-01-03	Reata Pharmaceuticals Inc.	Forms of CDDO methyl ester
BRPI0907423A2 (pt) *	2008-01-11	2020-10-27	Reata Pharmaceuticals, Inc.	composto triterpenoide sintético para uso em um método de melhoria da função renal em um indivíduo, e uso do referido composto
MX2010011439A (es)	2008-04-18	2011-01-25	Reata Pharmaceuticals Inc	Moduladores de inflamacion antioxidantes: derivados del acido oleanolico homologacion c-17.
JP5529851B2 (ja)	2008-04-18	2014-06-25	リアタファーマシューティカルズインコーポレイテッド	抗酸化炎症モジュレーター：ｃ−１７においてアミノ改変およびその他の改変を加えたオレアノール酸誘導体
WO2009146218A2 (en)	2008-04-18	2009-12-03	Reata Pharmaceuticals, Inc.	Compounds including an anti-inflammatory pharmacore and methods of use
US8071632B2 (en)	2008-04-18	2011-12-06	Reata Pharmaceuticals, Inc.	Antioxidant inflammation modulators: novel derivatives of oleanolic acid
KR101713140B1 (ko)	2008-04-18	2017-03-08	리타 파마슈티컬스 잉크.	Ｃ-환에서 포화된 산화방지성 염증 조절제 올레아놀산 유도체
EP2309860B1 (en)	2008-07-22	2014-01-08	Trustees of Dartmouth College	Monocyclic cyanoenones and methods of use thereof
SI2395979T1 (sl) *	2009-02-13	2017-12-29	Reata Pharmaceuticals, Inc.	Peroralni farmacevtski sestavki, ki vsebujejo amorfni CDDO-Me, z zapoznelim sproščanjem
DK2536285T3 (en)	2010-02-18	2018-07-16	Vtv Therapeutics Llc	Substituted fused imidazole derivatives, pharmaceutical compositions and methods for their use
US8759535B2 (en)	2010-02-18	2014-06-24	High Point Pharmaceuticals, Llc	Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof
DK2558105T3 (da)	2010-04-12	2020-01-27	Reata Pharmaceuticals Inc	Bardoxolonmethyl til behandling af fedme
CN103596929B (zh)	2010-12-17	2016-10-19	里亚塔医药公司	作为抗氧化发炎调节剂的吡唑及嘧啶三环烯酮
MX348862B (es)	2011-03-11	2017-07-03	Reata Pharmaceuticals Inc	Derivados c4-monometil triterpenoides y sus metodos de uso.
CN103156861B (zh) *	2011-12-08	2015-11-25	陈丽梅	齐敦果酸衍生物及其可药用盐在治疗糖尿病眼病中的应用
TWI623548B (zh)	2012-04-27	2018-05-11	瑞塔醫藥有限責任公司	齊墩果酸（ｂａｒｄｏｘｏｌｏｎｅｍｅｔｈｙｌ）之２，２-二氟基丙醯胺衍生物、多晶型及其使用方法
US8921419B2 (en)	2012-05-08	2014-12-30	Trustees Of Dartmouth College	Triterpenoids and compositions containing the same
US8981144B2 (en)	2012-05-08	2015-03-17	Trustees Of Dartmouth College	Method for synthesizing 2-cyano-3,12-dioxoolean-1, 9(11)-dien-28-oic acid methyl ester and derivatives thereof
WO2013188818A1 (en)	2012-06-15	2013-12-19	Reata Pharmaceuticals, Inc.	A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
JP2015527407A (ja) *	2012-09-10	2015-09-17	アッヴィ・インコーポレイテッド	グリチルレチン酸誘導体およびその使用方法
JP6243428B2 (ja)	2012-09-10	2017-12-06	リアタファーマシューティカルズインコーポレイテッド	オレアノール酸のｃ１７−アルカンジイルおよびアルケンジイル誘導体ならびにその使用方法
WO2014040073A1 (en)	2012-09-10	2014-03-13	Reata Pharmaceuticals, Inc.	C13-hydroxy derivatives of oleanolic acid and methods of use thereof
US9512094B2 (en)	2012-09-10	2016-12-06	Reata Pharmaceuticals, Inc.	C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
EP2739639A4 (en)	2012-09-28	2014-11-05	Applied Pharmaceutical Science Inc	POLYMORPHES OF CDDO ETHYL SITES AND USES THEREOF
CN102887936A (zh) *	2012-10-24	2013-01-23	苏州晶云药物科技有限公司	2-氰基-3,12-二氧代齐墩果-1,9(11)-二烯-28-酸甲酯晶型
CN102875634B (zh) *	2012-10-24	2014-08-20	苏州晶云药物科技有限公司	2-氰基-3,12-二氧代齐墩果-1,9(11)-二烯-28-酸甲酯的几种晶型
WO2014148455A1 (ja)	2013-03-19	2014-09-25	第一三共株式会社	テルペノイド誘導体
AR096046A1 (es)	2013-04-24	2015-12-02	Abbvie Inc	Derivados de 2,2-difluoropropanamida de metil bardoxolona, formas polimórficas y métodos de uso
EP4736949A2 (en)	2013-08-23	2026-05-06	Reata Pharmaceuticals Holdings, LLC	Methods of treating and preventing endothelial dysfunction using bardoxolone methyl or analogs thereof
US10189791B2 (en)	2014-08-26	2019-01-29	Trustees Of Dartmouth College	Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole
WO2016033132A1 (en)	2014-08-26	2016-03-03	Trustees Of Dartmouth College	Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole
KR20170055482A (ko)	2014-09-10	2017-05-19	다이이찌 산쿄 가부시키가이샤	안질환 치료용 및 예방용 서방성 의약 조성물
WO2016089648A1 (en)	2014-12-01	2016-06-09	Vtv Therapeutics Llc	Bach 1 inhibitors in combination with nrf2 activators and pharmaceutical compositions thereof
KR102594322B1 (ko)	2014-12-19	2023-10-26	가이스틀리히 파마 아게	옥사티아진-유사 화합물의 제조방법
US11591302B2 (en)	2014-12-19	2023-02-28	Geistlich Pharm A Ag	Processes for preparing oxathiazin-like compounds
EP3256451B1 (en)	2015-02-12	2021-10-20	Reata Pharmaceuticals, Inc.	Imidazolyl tricyclic enones as antioxidant inflammation modulators
HUE062258T2 (hu) *	2015-07-02	2023-10-28	Acerta Pharma Bv	(S)-4-(8-amino-3-(1-(but-2-inoil)pirrolidin-2-il)imidazo[1,5-a]pirazin-1-il)-N-(piridin-2-il)benzamid szilárd alakjai és készítményei
JP7074674B2 (ja)	2015-09-23	2022-05-24	リアタファーマシューティカルズインコーポレイテッド	Ｉｌ－１７の阻害及び他の使用のためのｃ４修飾オレアノール酸誘導体
CN110198718B (zh)	2016-11-08	2023-01-10	里亚塔医药控股有限责任公司	使用甲基巴多索隆或其类似物治疗阿尔波特综合征的方法
TWI831738B (zh)	2016-12-16	2024-02-11	美商瑞塔醫藥有限責任公司	用於抑制ＲＯＲγ及其他用途的嘧啶三環烯酮衍生物
US11427533B2 (en)	2017-07-13	2022-08-30	Pliva Hrvatska D.O.O.	Crystalline polymorphs of bardoxolone methyl
ES2967689T3 (es)	2018-04-06	2024-05-03	Capsugel Belgium Nv	Proceso de secado por aspersión para partículas de baja relación de aspecto que comprenden poli[(metacrilato de metilo)-co-(ácido metacrílico)]
US11993574B2 (en)	2018-06-15	2024-05-28	Reata Pharmaceuticals, Inc	Pyrazole and imidazole compounds for inhibition of IL-17 and RORgamma
US12060340B2 (en)	2018-06-20	2024-08-13	Reata Pharmaceuticals, Inc	Cysteine-dependent inverse agonists of nuclear receptors ROR-gamma/ROR-gamma-t and methods of treating diseases or disorders therewith
CN113164436A (zh)	2018-11-27	2021-07-23	协和麒麟株式会社	药物组合物
EP3999522B1 (en)	2019-07-19	2025-09-03	Reata Pharmaceuticals, Inc.	C17 polar-substituted heteroaromatic synthetic triterpenoids and methods of use thereof
BR112022022599A2 (pt)	2020-05-09	2023-03-21	Reata Pharmaceuticals Holdings Llc	Métodos de tratamento de covid-19 usando bardoxolona metil ou análogos da mesma
US12059419B2 (en)	2020-10-16	2024-08-13	Idience Co., Ltd.	Pharmaceutical composition comprising phthalazinone derivatives
AU2021397631A1 (en)	2020-12-11	2023-07-20	Reata Pharmaceuticals Holdings, LLC	Synthetic triterpenoids for use in therapy

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1317599C (en) *	1986-03-26	1993-05-11	Yukio Nezu	1,2,6-triphenyl-4(1h)-pyridinone derivatives, production and uses thereof
JPH01273020A (ja) *	1988-04-26	1989-10-31	Toray Ind Inc	有機非線形光学材料
US5064823A (en) *	1988-08-24	1991-11-12	Research Triangle Institute	Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers
JP2876144B2 (ja) *	1990-03-23	1999-03-31	東洋フアルマー株式会社	３―フェニルクマリン―７―イルオキシ酢酸誘導体とその製法及び用途
GB9622173D0 (en) *	1996-10-24	1996-12-18	Glaxo Group Ltd	Particulate Products
US20050276836A1 (en) *	1997-06-11	2005-12-15	Michelle Wilson	Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
US6326507B1 (en)	1998-06-19	2001-12-04	Trustees Of Dartmouth College	Therapeutic compounds and methods of use
US6890946B2 (en) *	1999-12-23	2005-05-10	Indiana University Research And Technology Corporation	Use of parthenolide to inhibit cancer
US7435755B2 (en) *	2000-11-28	2008-10-14	The Trustees Of Dartmouth College	CDDO-compounds and combination therapies thereof
WO2002047611A2 (en) *	2000-11-28	2002-06-20	Board Of Regents, The University Of Texas System	Cddo-compounds and combination therapies thereof
JP2006515859A (ja) *	2002-05-13	2006-06-08	トラスティーズオブダートマスカレッジ	阻害剤およびその使用法
JP3618341B2 (ja) *	2003-04-15	2005-02-09	山之内製薬株式会社	臭化物及びその結晶
FR2861299B1 (fr) *	2003-10-28	2006-01-27	Pf Medicament	Compositions pharmaceutiques a base de derives d'idasoxan sous formes polymorphes
WO2005057275A1 (ja)	2003-12-08	2005-06-23	Sony Corporation	液晶表示装置およびバックライト調整方法
US20060167097A1 (en) *	2004-04-16	2006-07-27	Cheppail Ramachandran	Compositions and uses of Amooranin compounds
BRPI0611375A2 (pt) *	2005-05-23	2010-08-31	Novartis Ag	formas cristalinas e outras de sais de ácido láctico de 4-amino-5-flúor-3-[6-(4-metilpiperazin-1-il)-1h-benzimid azol-2-il]-1h-quinolin-2-ona
DE102005041613A1 (de)	2005-09-01	2007-03-08	Ergonex Pharma Gmbh	Pharmazeutische Zusammensetzungen zur Behandlung von Karzinoid-Syndrom
NZ569078A (en)	2005-12-12	2012-01-12	Mosamedix Bv	Annexin derivatives suitable for pretargeting in therapy and diagnosis
US8088824B2 (en) *	2007-08-15	2012-01-03	Reata Pharmaceuticals Inc.	Forms of CDDO methyl ester

2008
- 2008-08-13 US US12/191,176 patent/US8088824B2/en active Active
- 2008-08-14 CA CA2871864A patent/CA2871864C/en active Active
- 2008-08-14 PL PL08795303T patent/PL2187741T3/pl unknown
- 2008-08-14 EP EP12153605.6A patent/EP2450057B1/en active Active
- 2008-08-14 CN CN2008801112346A patent/CN101820758B/zh active Active
- 2008-08-14 TW TW102134576A patent/TWI486357B/zh active
- 2008-08-14 HU HUE12153605A patent/HUE031866T2/en unknown
- 2008-08-14 EA EA201070149A patent/EA018704B1/ru unknown
- 2008-08-14 CA CA2696330A patent/CA2696330C/en active Active
- 2008-08-14 JP JP2010521031A patent/JP5005812B2/ja active Active
- 2008-08-14 CL CL2008002417A patent/CL2008002417A1/es unknown
- 2008-08-14 MX MX2010001628A patent/MX2010001628A/es active IP Right Grant
- 2008-08-14 AT AT08795303T patent/ATE549035T1/de active
- 2008-08-14 ES ES08795303T patent/ES2382571T3/es active Active
- 2008-08-14 PT PT08795303T patent/PT2187741E/pt unknown
- 2008-08-14 KR KR1020107005094A patent/KR101481764B1/ko active Active
- 2008-08-14 SG SG10201504650VA patent/SG10201504650VA/en unknown
- 2008-08-14 EA EA201370109A patent/EA023550B1/ru unknown
- 2008-08-14 SI SI200830650T patent/SI2187741T1/sl unknown
- 2008-08-14 TW TW097130947A patent/TWI419899B/zh active
- 2008-08-14 AU AU2008287388A patent/AU2008287388B2/en active Active
- 2008-08-14 DK DK12153605.6T patent/DK2450057T3/en active
- 2008-08-14 CN CN201310016448.8A patent/CN103254267B/zh active Active
- 2008-08-14 LT LTEP12153605.6T patent/LT2450057T/lt unknown
- 2008-08-14 ES ES12153605.6T patent/ES2602978T3/es active Active
- 2008-08-14 HR HRP20120350AT patent/HRP20120350T1/hr unknown
- 2008-08-14 BR BRPI0815540A patent/BRPI0815540A8/pt not_active Application Discontinuation
- 2008-08-14 NZ NZ583269A patent/NZ583269A/en unknown
- 2008-08-14 PL PL12153605T patent/PL2450057T3/pl unknown
- 2008-08-14 WO PCT/US2008/009703 patent/WO2009023232A1/en not_active Ceased
- 2008-08-14 KR KR1020147002848A patent/KR101544766B1/ko active Active
- 2008-08-14 SI SI200831728A patent/SI2450057T1/sl unknown
- 2008-08-14 AR ARP080103557A patent/AR073155A1/es unknown
- 2008-08-14 DK DK08795303.0T patent/DK2187741T3/da active
- 2008-08-14 SG SG2011094158A patent/SG177905A1/en unknown
- 2008-08-14 PT PT121536056T patent/PT2450057T/pt unknown
- 2008-08-14 EP EP08795303A patent/EP2187741B1/en active Active
2010
- 2010-02-09 IL IL203824A patent/IL203824A/en active IP Right Grant
- 2010-02-12 ZA ZA201001066A patent/ZA201001066B/xx unknown
2011
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2012
- 2012-05-23 JP JP2012117773A patent/JP2012188438A/ja active Pending
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JP2012188438A (ja)	2012-10-04
HUE031866T2 (en)	2017-08-28
BRPI0815540A8 (pt)	2023-04-11
AR073155A1 (es)	2010-10-20
DK2187741T3 (da)	2012-04-16
EA201070149A1 (ru)	2010-08-30
TW200916476A (en)	2009-04-16
CN103254267B (zh)	2016-03-16
US8633243B2 (en)	2014-01-21
US20120330050A1 (en)	2012-12-27
EP2450057A1 (en)	2012-05-09
CA2696330C (en)	2015-03-24
TWI419899B (zh)	2013-12-21
JP5005812B2 (ja)	2012-08-22
DK2450057T3 (en)	2016-12-19
HK1143537A1 (en)	2011-01-07
SG177905A1 (en)	2012-02-28
CN103254267A (zh)	2013-08-21
KR20100056488A (ko)	2010-05-27
EP2187741A1 (en)	2010-05-26
IL203824A (en)	2017-04-30
HRP20120350T1 (hr)	2012-05-31
ZA201001066B (en)	2010-10-27
CN101820758B (zh)	2013-03-06
US8309601B2 (en)	2012-11-13
JP2018009001A (ja)	2018-01-18
SI2450057T1 (sl)	2017-01-31
JP2015164939A (ja)	2015-09-17
CY1112864T1 (el)	2016-04-13
LT2450057T (lt)	2016-12-27
CL2008002417A1 (es)	2009-03-27
EP2450057B1 (en)	2016-09-28
KR101481764B1 (ko)	2015-01-13
CA2871864A1 (en)	2009-02-19
IL251419A0 (en)	2017-05-29
CA2871864C (en)	2016-05-17
AR119704A2 (es)	2022-01-05
BRPI0815540A2 (pt)	2014-09-30
AU2008287388B2 (en)	2014-11-06
MX2010001628A (es)	2010-06-02
KR101544766B1 (ko)	2015-08-17
EA018704B1 (ru)	2013-10-30
EA201370109A1 (ru)	2014-01-30
KR20140024063A (ko)	2014-02-27
TW201402597A (zh)	2014-01-16
PL2450057T3 (pl)	2017-02-28
EP2187741B1 (en)	2012-03-14
ES2602978T3 (es)	2017-02-23
EA023550B1 (ru)	2016-06-30
CN101820758A (zh)	2010-09-01
ATE549035T1 (de)	2012-03-15
HRP20161503T1 (hr)	2017-01-13
CY1118329T1 (el)	2017-06-28
JP2010536754A (ja)	2010-12-02
US8088824B2 (en)	2012-01-03
US20090048204A1 (en)	2009-02-19
TWI486357B (zh)	2015-06-01
CA2696330A1 (en)	2009-02-19
ES2382571T3 (es)	2012-06-11
PT2450057T (pt)	2016-12-15
US20120071684A1 (en)	2012-03-22
EP2187741A4 (en)	2010-08-25
WO2009023232A1 (en)	2009-02-19
NZ583269A (en)	2012-03-30
SG10201504650VA (en)	2015-07-30
SI2187741T1 (sl)	2012-07-31
PT2187741E (pt)	2012-06-21
AU2008287388A1 (en)	2009-02-19

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