PL2252628T3 - Koniugaty antagonistów peptydowych analogu bombezyny - Google Patents

Koniugaty antagonistów peptydowych analogu bombezyny

Info

Publication number
PL2252628T3
PL2252628T3 PL09717301T PL09717301T PL2252628T3 PL 2252628 T3 PL2252628 T3 PL 2252628T3 PL 09717301 T PL09717301 T PL 09717301T PL 09717301 T PL09717301 T PL 09717301T PL 2252628 T3 PL2252628 T3 PL 2252628T3
Authority
PL
Poland
Prior art keywords
bombezin
peptide antagonists
analog peptide
analog
antagonists
Prior art date
Application number
PL09717301T
Other languages
English (en)
Inventor
Helmut Maecke
Jean Claude Reubi
Rosalba Mansi
Original Assignee
Universitätsspital Basel
Universität Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39677415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2252628(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universitätsspital Basel, Universität Bern filed Critical Universitätsspital Basel
Publication of PL2252628T3 publication Critical patent/PL2252628T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14Peptides being immobilised on, or in, an inorganic carrier
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086Bombesin; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL09717301T 2008-03-07 2009-02-27 Koniugaty antagonistów peptydowych analogu bombezyny PL2252628T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08075180A EP2100900A1 (en) 2008-03-07 2008-03-07 Bombesin analog peptide antagonist conjugates
EP09717301.7A EP2252628B1 (en) 2008-03-07 2009-02-27 Bombesin analog peptide antagonist conjugates

Publications (1)

Publication Number Publication Date
PL2252628T3 true PL2252628T3 (pl) 2017-07-31

Family

ID=39677415

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09717301T PL2252628T3 (pl) 2008-03-07 2009-02-27 Koniugaty antagonistów peptydowych analogu bombezyny

Country Status (33)

Country Link
US (2) US9035023B2 (pl)
EP (2) EP2100900A1 (pl)
JP (1) JP5784911B2 (pl)
KR (2) KR101734553B1 (pl)
CN (1) CN101965358B (pl)
AR (1) AR070809A1 (pl)
AU (1) AU2009221204C1 (pl)
BR (1) BRPI0909823B1 (pl)
CA (1) CA2717427C (pl)
CL (1) CL2009000537A1 (pl)
CO (1) CO6290707A2 (pl)
CR (1) CR11671A (pl)
CY (1) CY1118687T1 (pl)
DK (1) DK2252628T3 (pl)
DO (1) DOP2010000269A (pl)
EC (1) ECSP10010467A (pl)
ES (1) ES2615805T3 (pl)
HU (1) HUE032980T2 (pl)
IL (1) IL207264A (pl)
MX (1) MX2010009843A (pl)
NZ (1) NZ587795A (pl)
PA (1) PA8818501A1 (pl)
PE (1) PE20091753A1 (pl)
PL (1) PL2252628T3 (pl)
PT (1) PT2252628T (pl)
RU (1) RU2523531C2 (pl)
SI (1) SI2252628T1 (pl)
SV (1) SV2010003660A (pl)
TW (1) TWI515011B (pl)
UA (1) UA103314C2 (pl)
UY (1) UY31693A (pl)
WO (1) WO2009109332A1 (pl)
ZA (1) ZA201006385B (pl)

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WO2015185162A1 (en) 2014-06-06 2015-12-10 Technische Universität München Modified cyclopentapeptides and uses thereof
EP2954933A1 (en) 2014-06-10 2015-12-16 3B Pharmaceuticals GmbH Conjugate comprising a neurotensin receptor ligand
EP2954934A1 (en) 2014-06-11 2015-12-16 3B Pharmaceuticals GmbH Conjugate comprising a neurotensin receptor ligand and use thereof
AU2015273934B2 (en) 2014-06-10 2020-08-20 3B Pharmaceuticals Gmbh Conjugate comprising a neurotensin receptor ligand and use thereof
CN106794228B (zh) 2014-06-16 2021-09-03 科德克希思公司 用于治疗麸质不耐受和由其引起的病症的组合物和方法
CN104610431B (zh) * 2014-11-26 2017-12-15 南京市第一医院 一种多肽及其应用
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MA49398A (fr) * 2017-05-05 2020-04-22 Eric Steven Burak Anticorps monoclonaux anti-igf-1r et utilisations de ceux-ci
RU2681318C1 (ru) * 2017-11-24 2019-03-06 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Способ получения иммуносупрессорного пептида Abu-TGIRIS-Abu, меченного ионом Gd3+
AU2019469641B2 (en) * 2018-11-13 2025-04-03 Provincial Health Services Authority Radiolabeled bombesin-derived compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders
EP3997104A1 (en) 2019-07-08 2022-05-18 3B Pharmaceuticals GmbH Compounds comprising a fibroblast activation protein ligand and use thereof
EP3763726A1 (en) 2019-07-08 2021-01-13 3B Pharmaceuticals GmbH Compounds comprising a fibroblast activation protein ligand and use thereof
WO2021121734A1 (en) * 2019-12-19 2021-06-24 Technische Universität München Modified grpr antagonist peptides for imaging and therapy of cancer
WO2021250240A1 (en) 2020-06-12 2021-12-16 Orano Diaza-18-crown-6 derivative useful for chelating radium, conjugate and radium chelate comprising the same, and uses thereof
EP3973999A1 (en) * 2020-09-28 2022-03-30 Orano Med Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof
WO2022123462A1 (en) 2020-12-09 2022-06-16 3B Pharmaceuticals Gmbh Radiolabelled prostate specific membrane antigen (psma) inhibitors and use thereof
EP4050018A1 (en) 2021-01-07 2022-08-31 3B Pharmaceuticals GmbH Compounds comprising a fibroblast activation protein ligand and use thereof
AU2022262350B2 (en) 2021-04-20 2026-05-07 Terrapower Isotopes, Llc Titania based generators for ac-225 generation
KR20240133798A (ko) 2021-12-17 2024-09-04 쓰리비 파마슈티컬스 게엠베하 탄산 무수화효소 ix 리간드
EP4499663A1 (en) 2022-03-25 2025-02-05 Provincial Health Services Authority Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
CN119923279A (zh) 2022-09-07 2025-05-02 3B制药有限公司 前列腺特异性膜抗原(psma)配体及其用途
CN117919452B (zh) * 2023-03-09 2026-05-12 中国科学院宁波材料技术与工程研究所 一种亚细胞器主动靶向成像探针及其制备方法
WO2024212808A1 (zh) * 2023-04-10 2024-10-17 湖南中晟全肽生物科技股份有限公司 蛙皮素类多肽化合物及其用途
EP4455159A1 (en) 2023-04-25 2024-10-30 3B Pharmaceuticals GmbH Gastric inhibitory peptide receptor ligands with bio-distribution modifier
WO2025054727A1 (en) * 2023-09-13 2025-03-20 Provincial Health Services Authority Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
CN120019818A (zh) * 2023-11-20 2025-05-20 湖南中晟全肽生物科技股份有限公司 一种多肽偶联药物及其制备方法和用途
WO2025109003A1 (en) 2023-11-21 2025-05-30 3B Pharmaceuticals Gmbh P-cadherin ligands
WO2025119203A1 (zh) * 2023-12-05 2025-06-12 烟台蓝纳成生物技术有限公司 一种异二聚体放射性核素偶联药物、制备及其应用
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Also Published As

Publication number Publication date
IL207264A0 (en) 2011-08-01
EP2252628A1 (en) 2010-11-24
AR070809A1 (es) 2010-05-05
BRPI0909823A2 (pt) 2019-03-06
TW200944239A (en) 2009-11-01
US20150265733A1 (en) 2015-09-24
PA8818501A1 (es) 2010-04-21
KR101734553B1 (ko) 2017-05-11
JP5784911B2 (ja) 2015-09-24
CY1118687T1 (el) 2017-07-12
UA103314C2 (ru) 2013-10-10
US20110097266A1 (en) 2011-04-28
PE20091753A1 (es) 2009-12-13
DK2252628T3 (en) 2017-02-06
AU2009221204A1 (en) 2009-09-11
DOP2010000269A (es) 2010-10-31
HUE032980T2 (en) 2017-11-28
US9035023B2 (en) 2015-05-19
SV2010003660A (es) 2011-02-17
BRPI0909823B1 (pt) 2022-04-19
SI2252628T1 (sl) 2017-05-31
CA2717427A1 (en) 2009-09-11
PT2252628T (pt) 2017-02-10
ZA201006385B (en) 2016-10-26
RU2010140846A (ru) 2012-04-20
AU2009221204C1 (en) 2016-12-08
KR20110014565A (ko) 2011-02-11
CL2009000537A1 (es) 2010-07-19
CA2717427C (en) 2016-02-23
NZ587795A (en) 2012-07-27
RU2523531C2 (ru) 2014-07-20
CN101965358B (zh) 2019-09-03
ECSP10010467A (es) 2010-10-30
AU2009221204B2 (en) 2013-09-05
WO2009109332A1 (en) 2009-09-11
EP2100900A1 (en) 2009-09-16
MX2010009843A (es) 2011-03-04
CN101965358A (zh) 2011-02-02
CR11671A (es) 2010-11-01
CO6290707A2 (es) 2011-06-20
KR20160128425A (ko) 2016-11-07
JP2011515338A (ja) 2011-05-19
UY31693A (es) 2010-01-05
EP2252628B1 (en) 2016-12-28
IL207264A (en) 2017-02-28
TWI515011B (zh) 2016-01-01
ES2615805T3 (es) 2017-06-08

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