PL2371853T3 - Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna, zastosowanie pochodnej insuliny lub jej farmaceutycznie dopuszczalnej soli oraz sposób leczenia - Google Patents

Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna, zastosowanie pochodnej insuliny lub jej farmaceutycznie dopuszczalnej soli oraz sposób leczenia

Info

Publication number
PL2371853T3
PL2371853T3 PL11003008T PL11003008T PL2371853T3 PL 2371853 T3 PL2371853 T3 PL 2371853T3 PL 11003008 T PL11003008 T PL 11003008T PL 11003008 T PL11003008 T PL 11003008T PL 2371853 T3 PL2371853 T3 PL 2371853T3
Authority
PL
Poland
Prior art keywords
pharmaceutically acceptable
acceptable salt
insulin
treatment
pharmaceutical composition
Prior art date
Application number
PL11003008T
Other languages
English (en)
Inventor
Piotr Borowicz
Wojciech SŁAWIŃSKI
Andrzej PŁUCIENNICZAK
Jerzy MIKOŁAJCZYK
Tadeusz Głabski
Dariusz Kurzynoga
Diana MIKIEWICZ-SYGUŁA
Anna WÓJTOWICZ-KRAWIEC
Marcin ZIELIŃSKI
Małgorzata KĘSIK-BRODACKA
Violetta Cecuda-Adamczewska
Iwona SOKOŁOWSKA
Grażyna PŁUCIENNICZAK
Dorota Stadnik
Jarosław ANTOSIK
Jacek Pstrzoch
Justyna Bernat
Tomasz Pawlukowiec
Jacek STĘPNIEWSKI
Monika Bogiel
Original Assignee
Instytut Biotechnologii i Antybiotyków
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Biotechnologii i Antybiotyków filed Critical Instytut Biotechnologii i Antybiotyków
Publication of PL2371853T3 publication Critical patent/PL2371853T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
PL11003008T 2008-07-04 2009-07-04 Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna, zastosowanie pochodnej insuliny lub jej farmaceutycznie dopuszczalnej soli oraz sposób leczenia PL2371853T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PL385586A PL219335B1 (pl) 2008-07-04 2008-07-04 Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna
EP11003008.7A EP2371853B1 (en) 2008-07-04 2009-07-04 Insulin derivatives or its pharmaceutically acceptable salt, pharmaceutical composition, use of insulin derivative or its pharmaceutically acceptable salt and method of treatment
EP09773816A EP2321344A2 (en) 2008-07-04 2009-07-04 New insulin analogues of prolonged activity

Publications (1)

Publication Number Publication Date
PL2371853T3 true PL2371853T3 (pl) 2018-06-29

Family

ID=41130257

Family Applications (2)

Application Number Title Priority Date Filing Date
PL385586A PL219335B1 (pl) 2008-07-04 2008-07-04 Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna
PL11003008T PL2371853T3 (pl) 2008-07-04 2009-07-04 Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna, zastosowanie pochodnej insuliny lub jej farmaceutycznie dopuszczalnej soli oraz sposób leczenia

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL385586A PL219335B1 (pl) 2008-07-04 2008-07-04 Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna

Country Status (8)

Country Link
US (2) US8618048B2 (pl)
EP (2) EP2371853B1 (pl)
JP (1) JP2011526886A (pl)
CN (1) CN102083855A (pl)
CA (1) CA2729938C (pl)
EA (1) EA023559B1 (pl)
PL (2) PL219335B1 (pl)
WO (1) WO2010002283A2 (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10100098B2 (en) 2006-12-13 2018-10-16 Stelis Biopharma Private Limited Insulin production methods and proinsulin constructs
AU2008365557A1 (en) 2008-12-15 2011-07-21 Zealand Pharma A/S Glucagon analogues
EA020537B1 (ru) 2008-12-15 2014-11-28 Зилэнд Фарма А/С Аналоги глюкагона
MX2011006314A (es) 2008-12-15 2011-09-22 Zealand Pharma As Analogos de glucagon.
PL2370462T3 (pl) 2008-12-15 2015-01-30 Zealand Pharma As Analogi glukagonu
AP3329A (en) 2009-07-13 2015-06-30 Zealand Pharma As Acylated glucagon analogues
UY33462A (es) 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
KR20130086343A (ko) 2010-06-24 2013-08-01 질랜드 파마 에이/에스 글루카곤 유사체
SG192038A1 (en) 2011-01-20 2013-08-30 Zealand Pharma As Combination of acylated glucagon analogues with insulin analogues
WO2012115638A1 (en) * 2011-02-23 2012-08-30 Elona Biotechnologies Glargine proinsulin compositions and methods of producing glargine insulin analogs therefrom
NZ702333A (en) 2012-05-03 2017-06-30 Zealand Pharma As Gip-glp-1 dual agonist compounds and methods
PL222975B1 (pl) * 2012-05-23 2016-09-30 Inst Biotechnologii I Antybiotyków Analog insuliny lub jego farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna o przedłużonym działaniu terapeutycznym oraz zastosowanie analogu insuliny
WO2014015078A1 (en) * 2012-07-17 2014-01-23 Michael Weiss O-linked carbohydrate-modified insulin analogues
US9624287B2 (en) 2012-07-17 2017-04-18 Case Western Reserve University O-linked carbohydrate-modified insulin analogues
MX356957B (es) 2012-07-23 2018-06-20 Zealand Pharma As Analogos del glucagon.
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
EP2945643A4 (en) * 2013-01-15 2017-04-26 Phasebio Pharmaceuticals, Inc. Therapeutic agents, compositions, and methods for glycemic control
WO2014122651A1 (en) * 2013-02-07 2014-08-14 Valin Technologies Ltd. Process for preparing insulin
CN103981242A (zh) * 2013-02-07 2014-08-13 华凌科技有限公司 胰岛素的制备方法
WO2014122653A1 (en) * 2013-02-07 2014-08-14 Valin Technologies Ltd. Process for preparing insulin
CN103981243A (zh) * 2013-02-07 2014-08-13 华凌科技有限公司 胰岛素的制备方法
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
LT3057984T (lt) 2013-10-17 2018-12-27 Zealand Pharma A/S Acilinti gliukagono analogai
KR102310392B1 (ko) 2013-11-06 2021-10-13 질랜드 파마 에이/에스 글루카곤-glp-1-gip 삼원 효능제 화합물
AU2014345569B2 (en) 2013-11-06 2020-08-13 Zealand Pharma A/S GIP-GLP-1 dual agonist compounds and methods
RU2716985C2 (ru) 2014-10-29 2020-03-17 Зилэнд Фарма А/С Соединения-агонисты gip и способы
JP6989385B2 (ja) 2015-04-16 2022-01-05 ジーランド ファーマ アクティーゼルスカブ アシル化グルカゴン類似体
PL239062B1 (pl) * 2016-01-22 2021-11-02 Inst Biotechnologii I Antybiotykow Sposób wytwarzania insuliny i jej pochodnych
CA3044565A1 (en) * 2016-11-21 2018-05-24 Case Western Reserve University Rapid-acting insulin analogues of enhanced stability
KR102666154B1 (ko) * 2018-08-08 2024-05-20 주식회사 대웅제약 지속형 인슐린 아날로그 및 그 복합체
WO2020120477A1 (en) 2018-12-11 2020-06-18 Sanofi Insulin analogs having reduced insulin receptor binding affinity
WO2021081335A1 (en) * 2019-10-24 2021-04-29 University Of Utah Research Foundation Novel mini-insulin with extended c-terminal a chain

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
US5434247A (en) * 1986-10-10 1995-07-18 Board Of Regents, The University Of Texas System Peptides for inducing monocyte cytotoxicity in diagnostics
US5135736A (en) * 1988-08-15 1992-08-04 Neorx Corporation Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
EP0547544B1 (de) * 1991-12-18 1997-03-12 Hoechst Aktiengesellschaft Verfahren zur Gewinnung von insulinhaltigen Lösungen
ES2190784T3 (es) * 1992-02-28 2003-08-16 Autoimmune Inc Supresion de enfermedades autoinmunes por antigenos espectadores.
DE4405179A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
CA2356109C (en) * 1999-01-06 2008-04-22 Genentech, Inc. Insulin-like growth factor (igf) i mutant variants
US6777207B2 (en) * 1999-12-29 2004-08-17 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
ATE405660T1 (de) 2003-06-17 2008-09-15 Sembiosys Genetics Inc Verfahren zur insulinproduktion in pflanzen
PL213561B1 (pl) 2004-01-09 2013-03-29 Inst Biotechnologii I Antybiotykow Sposób otrzymywania plazmidu, plazmid oraz zastosowania
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
EP2801366A3 (en) * 2004-09-02 2015-04-29 Cognosci, Inc. Improved apo E analogs and methods for their use
PL373543A1 (pl) * 2005-03-10 2006-09-18 Instytut Biotechnologii i Antybiotyków Kompozycja farmaceutyczna zawierająca biosyntetyczny analog insuliny ludzkiej, oraz jej zastosowanie w terapii cukrzycy
AU2006259307B2 (en) * 2005-06-17 2012-12-20 Mannkind Corporation Epitope analogues
DE102005051366A1 (de) * 2005-10-25 2007-04-26 Degussa Gmbh Drug Delivery Systeme
JP2009530243A (ja) * 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー/エス アシル化単鎖インスリン
JP5550338B2 (ja) * 2006-07-31 2014-07-16 ノボ・ノルデイスク・エー/エス ペグ化持続型インスリン
WO2008049711A1 (en) * 2006-10-27 2008-05-02 Novo Nordisk A/S Peptide extended insulins

Also Published As

Publication number Publication date
US20140121353A1 (en) 2014-05-01
CN102083855A (zh) 2011-06-01
EP2371853A3 (en) 2012-10-03
JP2011526886A (ja) 2011-10-20
WO2010002283A9 (en) 2011-01-20
EP2321344A2 (en) 2011-05-18
CA2729938C (en) 2018-11-06
PL385586A1 (pl) 2010-01-18
EA201170149A1 (ru) 2011-06-30
CA2729938A1 (en) 2010-01-07
US8618048B2 (en) 2013-12-31
EA023559B1 (ru) 2016-06-30
WO2010002283A3 (en) 2010-04-29
EP2371853A2 (en) 2011-10-05
US20110136736A1 (en) 2011-06-09
EP2371853B1 (en) 2017-09-13
WO2010002283A2 (en) 2010-01-07
PL219335B1 (pl) 2015-04-30

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