PL2441760T3 - Związek o działaniu kurczącym mięsień-wypieracz i zwiotczającym mięsień-zwieracz cewki moczowej - Google Patents
Związek o działaniu kurczącym mięsień-wypieracz i zwiotczającym mięsień-zwieracz cewki moczowejInfo
- Publication number
- PL2441760T3 PL2441760T3 PL10786192T PL10786192T PL2441760T3 PL 2441760 T3 PL2441760 T3 PL 2441760T3 PL 10786192 T PL10786192 T PL 10786192T PL 10786192 T PL10786192 T PL 10786192T PL 2441760 T3 PL2441760 T3 PL 2441760T3
- Authority
- PL
- Poland
- Prior art keywords
- activity
- muscle
- compound
- urethral sphincter
- contracting
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 210000005070 sphincter Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009139657 | 2009-06-10 | ||
| JP2009256008 | 2009-11-09 | ||
| EP10786192.4A EP2441760B1 (en) | 2009-06-10 | 2010-06-09 | Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity |
| PCT/JP2010/059771 WO2010143661A1 (ja) | 2009-06-10 | 2010-06-09 | 膀胱排尿筋収縮および尿道括約筋弛緩作用を有する化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2441760T3 true PL2441760T3 (pl) | 2014-05-30 |
Family
ID=43308916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10786192T PL2441760T3 (pl) | 2009-06-10 | 2010-06-09 | Związek o działaniu kurczącym mięsień-wypieracz i zwiotczającym mięsień-zwieracz cewki moczowej |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US8410281B2 (pl) |
| EP (1) | EP2441760B1 (pl) |
| JP (1) | JP4807478B2 (pl) |
| KR (1) | KR101633149B1 (pl) |
| CN (1) | CN102803239B (pl) |
| AU (1) | AU2010259585B2 (pl) |
| BR (1) | BRPI1013152B1 (pl) |
| CA (1) | CA2764782C (pl) |
| DK (1) | DK2441760T3 (pl) |
| ES (1) | ES2444500T3 (pl) |
| IL (1) | IL216856A0 (pl) |
| MX (1) | MX2011013283A (pl) |
| NZ (1) | NZ596960A (pl) |
| PL (1) | PL2441760T3 (pl) |
| PT (1) | PT2441760E (pl) |
| RU (1) | RU2531350C2 (pl) |
| TW (1) | TWI437987B (pl) |
| WO (1) | WO2010143661A1 (pl) |
| ZA (1) | ZA201109103B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI437987B (zh) * | 2009-06-10 | 2014-05-21 | Ono Pharmaceutical Co | 具有膀胱排尿肌收縮及尿道括約肌鬆弛之作用的化合物 |
| DK2891651T3 (en) * | 2012-08-31 | 2017-06-06 | Ono Pharmaceutical Co | AMINAL SALT AND CRYSTALL THEREOF |
| CA2918245C (en) | 2013-08-01 | 2022-08-30 | Dignify Therapeutics, Inc. | Compositions and methods for inducing urinary voiding and defecation |
| CA2966594A1 (en) * | 2014-11-03 | 2016-05-12 | William Beaumont Hospital | Method for treating underactive bladder syndrome |
| KR102906464B1 (ko) * | 2018-12-31 | 2025-12-30 | 아다마 마켓심 리미티드 | 1,1,2-트리플루오로-4-(치환 설포닐)-부트-1-엔의 합성 |
| WO2021024253A1 (en) * | 2019-08-04 | 2021-02-11 | Yeda Research And Development Co. Ltd. | Process for the preparation of fluensulfone |
| CN119039235B (zh) * | 2024-08-20 | 2025-12-16 | 湖北省医药工业研究院有限公司 | 合成阿伐那非、中间体的方法及用途 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS503362B1 (pl) | 1970-06-10 | 1975-02-04 | ||
| JPS5231404B1 (pl) | 1971-04-28 | 1977-08-15 | ||
| JPS57156460A (en) | 1981-03-20 | 1982-09-27 | Ono Pharmaceut Co Ltd | Stabilized composition of prostaglandin and prostaglandin mimic compound, and its preparation |
| JPS60197667A (ja) | 1984-03-19 | 1985-10-07 | Ono Pharmaceut Co Ltd | 6―ケト―プロスタグランジン類似化合物及びその製造方法 |
| ATE237587T1 (de) | 1997-02-10 | 2003-05-15 | Ono Pharmaceutical Co | 11,15-o-dialkylprostaglandin-e-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese als aktiven inhaltsstoff enthalten |
| JPH11130678A (ja) | 1997-08-27 | 1999-05-18 | Kaken Pharmaceut Co Ltd | 神経圧迫による神経障害改善剤 |
| JP4273407B2 (ja) | 2001-07-23 | 2009-06-03 | 小野薬品工業株式会社 | Ep4アゴニストを有効成分とする骨量低下疾患の治療剤 |
| JP2005053707A (ja) | 2001-07-30 | 2005-03-03 | Kankyo Device Kenkyusho:Kk | 可視光応答性材料の製造方法 |
| AU2003211574A1 (en) | 2002-03-05 | 2003-09-16 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| WO2004008411A1 (en) | 2002-07-11 | 2004-01-22 | Nokia Corporation | Method and device for automatically changing a digital content on a mobile device according to sensor data |
| WO2004065365A1 (ja) | 2003-01-21 | 2004-08-05 | Ono Pharmaceutical Co., Ltd. | 8−アザプロスタグランジン誘導体およびその医薬用途 |
| WO2004089411A1 (ja) | 2003-04-03 | 2004-10-21 | Ono Pharmaceutical Co., Ltd. | 脊柱管狭窄症治療剤 |
| WO2005053707A1 (ja) | 2003-12-05 | 2005-06-16 | Ono Pharmaceutical Co., Ltd. | 馬尾神経組織血流増加剤 |
| WO2005061492A1 (ja) | 2003-12-22 | 2005-07-07 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびそれらを有効成分とする薬剤 |
| US7858610B2 (en) | 2004-08-10 | 2010-12-28 | Ono Pharmaceutical Co., Ltd. | Preventive and/or remedy for lower urinary tract diseases containing EP4 agonist |
| EP1806148A4 (en) | 2004-10-22 | 2009-12-02 | Ono Pharmaceutical Co | THERAPEUTIC PREPARATION FOR INHALATION |
| JP2006129788A (ja) | 2004-11-05 | 2006-05-25 | Nippon Starch Chemical Co Ltd | 揚げ物用ミックス |
| JP5040650B2 (ja) | 2005-06-03 | 2012-10-03 | 小野薬品工業株式会社 | 神経再生および/または保護剤 |
| WO2009148163A1 (ja) * | 2008-06-06 | 2009-12-10 | 小野薬品工業株式会社 | 膀胱排尿筋収縮および尿道括約筋弛緩剤 |
| TWI437987B (zh) * | 2009-06-10 | 2014-05-21 | Ono Pharmaceutical Co | 具有膀胱排尿肌收縮及尿道括約肌鬆弛之作用的化合物 |
-
2010
- 2010-06-09 TW TW099118684A patent/TWI437987B/zh not_active IP Right Cessation
- 2010-06-09 DK DK10786192.4T patent/DK2441760T3/en active
- 2010-06-09 CN CN201080035423.7A patent/CN102803239B/zh not_active Expired - Fee Related
- 2010-06-09 BR BRPI1013152-3A patent/BRPI1013152B1/pt not_active IP Right Cessation
- 2010-06-09 ES ES10786192.4T patent/ES2444500T3/es active Active
- 2010-06-09 RU RU2011152927/04A patent/RU2531350C2/ru active
- 2010-06-09 KR KR1020117029571A patent/KR101633149B1/ko not_active Expired - Fee Related
- 2010-06-09 CA CA2764782A patent/CA2764782C/en active Active
- 2010-06-09 WO PCT/JP2010/059771 patent/WO2010143661A1/ja not_active Ceased
- 2010-06-09 JP JP2011503274A patent/JP4807478B2/ja active Active
- 2010-06-09 PT PT107861924T patent/PT2441760E/pt unknown
- 2010-06-09 AU AU2010259585A patent/AU2010259585B2/en not_active Ceased
- 2010-06-09 NZ NZ596960A patent/NZ596960A/xx not_active IP Right Cessation
- 2010-06-09 PL PL10786192T patent/PL2441760T3/pl unknown
- 2010-06-09 MX MX2011013283A patent/MX2011013283A/es active IP Right Grant
- 2010-06-09 US US13/377,047 patent/US8410281B2/en not_active Expired - Fee Related
- 2010-06-09 EP EP10786192.4A patent/EP2441760B1/en active Active
-
2011
- 2011-12-08 IL IL216856A patent/IL216856A0/en active IP Right Grant
- 2011-12-09 ZA ZA2011/09103A patent/ZA201109103B/en unknown
-
2013
- 2013-03-04 US US13/784,008 patent/US8716490B2/en not_active Expired - Fee Related
-
2014
- 2014-02-12 US US14/178,901 patent/US9150528B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2444500T3 (es) | 2014-02-25 |
| TW201103539A (en) | 2011-02-01 |
| WO2010143661A1 (ja) | 2010-12-16 |
| KR101633149B1 (ko) | 2016-06-23 |
| US20140171387A1 (en) | 2014-06-19 |
| US9150528B2 (en) | 2015-10-06 |
| RU2531350C2 (ru) | 2014-10-20 |
| ZA201109103B (en) | 2012-08-29 |
| US8716490B2 (en) | 2014-05-06 |
| PT2441760E (pt) | 2014-01-07 |
| CN102803239A (zh) | 2012-11-28 |
| AU2010259585A1 (en) | 2012-01-19 |
| CA2764782A1 (en) | 2010-12-16 |
| BRPI1013152A2 (pt) | 2016-04-05 |
| DK2441760T3 (en) | 2014-02-17 |
| KR20120026088A (ko) | 2012-03-16 |
| TWI437987B (zh) | 2014-05-21 |
| NZ596960A (en) | 2013-04-26 |
| US8410281B2 (en) | 2013-04-02 |
| JP4807478B2 (ja) | 2011-11-02 |
| CA2764782C (en) | 2017-07-25 |
| EP2441760A1 (en) | 2012-04-18 |
| IL216856A0 (en) | 2012-03-01 |
| BRPI1013152B1 (pt) | 2019-06-18 |
| EP2441760A4 (en) | 2012-12-05 |
| EP2441760B1 (en) | 2013-11-20 |
| MX2011013283A (es) | 2012-01-12 |
| CN102803239B (zh) | 2015-04-15 |
| HK1169117A1 (en) | 2013-01-18 |
| US20130184236A1 (en) | 2013-07-18 |
| AU2010259585B2 (en) | 2015-11-19 |
| JPWO2010143661A1 (ja) | 2012-11-29 |
| US20120088805A1 (en) | 2012-04-12 |
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