PL2450446T3 - Zwiększanie poziomów alkaloidów nikotynowych - Google Patents

Zwiększanie poziomów alkaloidów nikotynowych

Info

Publication number
PL2450446T3
PL2450446T3 PL11187201T PL11187201T PL2450446T3 PL 2450446 T3 PL2450446 T3 PL 2450446T3 PL 11187201 T PL11187201 T PL 11187201T PL 11187201 T PL11187201 T PL 11187201T PL 2450446 T3 PL2450446 T3 PL 2450446T3
Authority
PL
Poland
Prior art keywords
increasing levels
nicotinic alkaloids
alkaloids
nicotinic
levels
Prior art date
Application number
PL11187201T
Other languages
English (en)
Inventor
Takashi Hashimoto
M Kajikawa
Original Assignee
22Nd Century Ltd Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 22Nd Century Ltd Llc filed Critical 22Nd Century Ltd Llc
Publication of PL2450446T3 publication Critical patent/PL2450446T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Pain & Pain Management (AREA)
PL11187201T 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych PL2450446T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06848676.0A EP2061889B1 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids
PCT/IB2006/004043 WO2007072224A2 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids
EP20110187201 EP2450446B1 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids

Publications (1)

Publication Number Publication Date
PL2450446T3 true PL2450446T3 (pl) 2015-10-30

Family

ID=38189038

Family Applications (3)

Application Number Title Priority Date Filing Date
PL14163682T PL2792750T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych
PL11187201T PL2450446T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych
PL06848676T PL2061889T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL14163682T PL2792750T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL06848676T PL2061889T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych

Country Status (9)

Country Link
EP (4) EP3578661A1 (pl)
JP (1) JP5087777B2 (pl)
ES (3) ES2478633T3 (pl)
HK (1) HK1203545A1 (pl)
HU (1) HUE026819T2 (pl)
PL (3) PL2792750T3 (pl)
PT (1) PT2450446E (pl)
TW (4) TWI659102B (pl)
WO (1) WO2007072224A2 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9102948B2 (en) 2006-11-17 2015-08-11 22Nd Century Limited, Llc Regulating alkaloids
JP5540068B2 (ja) * 2010-02-17 2014-07-02 日本たばこ産業株式会社 植物内容成分の調節因子、およびその利用
CN102258213B (zh) * 2011-02-25 2013-07-17 福州农博士生物技术有限公司 烟丝生产用复合酶菌制剂及其制备方法
WO2013107527A1 (en) * 2012-01-21 2013-07-25 Vib Vzw Novel genes and uses thereof for secondary metabolite production in plants
WO2014134354A1 (en) 2013-03-01 2014-09-04 North Carolina State University Transcription factors that regulate nicotine biosynthesis in tobacco
BR112021001364A2 (pt) * 2018-07-26 2021-04-20 Altria Client Services Llc composições e métodos à base de engenharia de pmt para produzir plantas de tabaco e produtos tendo níveis de alcaloides alterados
CN110452916B (zh) * 2019-09-03 2020-11-10 西南大学 莨菪醛还原酶及其应用
WO2021072288A1 (en) * 2019-10-10 2021-04-15 Altria Client Services Llc Compositions and methods based on qpt engineering for producing tobacco plants and products having altered alkaloid levels
CN113073062B (zh) * 2021-04-07 2023-03-31 广西中烟工业有限责任公司 一种复合微生物制剂及其制备方法和应用
KR102844466B1 (ko) * 2021-06-21 2025-08-11 주식회사 케이티앤지 Qpt 유전자가 조작된 식물 세포 및 이의 이용 방법

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
ES2187497T3 (es) 1990-04-12 2003-06-16 Syngenta Participations Ag Promotores preferentemente en tejidos.
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
US5852041A (en) 1993-04-07 1998-12-22 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acethylcholine receptors
US5633363A (en) 1994-06-03 1997-05-27 Iowa State University, Research Foundation In Root preferential promoter
US5837876A (en) 1995-07-28 1998-11-17 North Carolina State University Root cortex specific gene promoter
US6135121A (en) 1996-06-28 2000-10-24 Regent Court Technologies Tobacco products having reduced nitrosamine content
US5803081A (en) 1996-06-28 1998-09-08 Regent Court Technologies Tobacco and related products
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
SE9803986D0 (sv) * 1998-11-23 1998-11-23 Pharmacia & Upjohn Ab New compositions
WO2000052168A1 (en) 1999-02-26 2000-09-08 Cropdesign N.V. Method of selecting transformed cells and tissues
US6805134B2 (en) 1999-04-26 2004-10-19 R. J. Reynolds Tobacco Company Tobacco processing
FR2795424B1 (fr) 1999-06-25 2003-12-05 Agronomique Inst Nat Rech Promoteur s'exprimant specifiquement dans les cellules de racines de plantes, vecteurs et cellules hotes recombinantes comprenant un tel promoteur et plantes transgeniques obtenues
US6723896B1 (en) 1999-11-12 2004-04-20 The Rockefeller University Inducible site-specific recombination for the activation and removal of transgenes in transgenic plants
JP2003521940A (ja) 2000-02-08 2003-07-22 株式会社サカタのタネ 植物形質転換のための新規方法および構築物
EP1368467B1 (en) 2000-11-07 2007-04-25 North Carolina State University Putrescine-n-methyltransferase promoter
AU2002228901A1 (en) 2000-11-10 2002-05-21 Vector Tobacco (Bermuda) Ltd. Method and product for removing carcinogens from tobacco smoke
US20030084473A1 (en) 2001-08-09 2003-05-01 Valigen Non-transgenic herbicide resistant plants
ATE539084T1 (de) 2001-11-07 2012-01-15 Syngenta Participations Ag Promotoren zur regulierung der genexpression in pflanzenwurzeln
US7700834B2 (en) 2001-11-13 2010-04-20 U.S. Smokless Tobacco Company Nicotiana nucleic acid molecules and uses thereof
US7700851B2 (en) 2001-11-13 2010-04-20 U.S. Smokeless Tobacco Company Tobacco nicotine demethylase genomic clone and uses thereof
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
US7534934B2 (en) 2002-02-20 2009-05-19 J.R. Simplot Company Precise breeding
AU2003219806B8 (en) 2002-02-20 2011-01-27 J.R. Simplot Company Precise breeding
CA2481167A1 (en) 2002-04-09 2003-10-23 Vector Tobacco Ltd. Tobacco having reduced nicotine and nitrosamines
EP1578422B1 (en) * 2002-12-20 2007-04-11 NicoNovum AB A physically and chemically stable nicotine and micorcrystalline cellulose containing particulate material
US20050034365A1 (en) 2003-01-31 2005-02-17 Philip Morris Usa Inc. Spray and/or soil treatment of tobacco to reduce TSNAs
WO2004076625A2 (en) 2003-02-21 2004-09-10 Vector Tobacco Ltd. Method of identifying plant cells transformed with a gene
OA13241A (en) 2003-08-19 2007-01-31 22Nd Century Ltd Llc Reduced-exposure tobacco products.
US7411112B2 (en) 2003-10-09 2008-08-12 Pioneer Hi-Bred International, Inc. Maize promoter named CRWAQ81
ATE530656T1 (de) 2005-02-23 2011-11-15 Univ North Carolina State Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene.
JP4892744B2 (ja) * 2005-02-28 2012-03-07 国立大学法人 奈良先端科学技術大学院大学 植物におけるニコチン類縁アルカロイド量を低下させる方法

Also Published As

Publication number Publication date
ES2748823T3 (es) 2020-03-18
WO2007072224A2 (en) 2007-06-28
EP3578661A1 (en) 2019-12-11
JP2010505449A (ja) 2010-02-25
WO2007072224A8 (en) 2009-04-23
TWI421341B (zh) 2014-01-01
PL2061889T3 (pl) 2014-11-28
TW201414834A (zh) 2014-04-16
EP2792750B1 (en) 2019-07-03
TW201623611A (zh) 2016-07-01
TW200817509A (en) 2008-04-16
EP2450446A2 (en) 2012-05-09
EP2792750A1 (en) 2014-10-22
PL2792750T3 (pl) 2020-02-28
JP5087777B2 (ja) 2012-12-05
HUE026819T2 (en) 2016-07-28
EP2450446A3 (en) 2012-07-11
ES2478633T3 (es) 2014-07-22
EP2061889A2 (en) 2009-05-27
WO2007072224A3 (en) 2008-04-17
TW201925466A (zh) 2019-07-01
HK1169677A1 (en) 2013-02-01
PT2450446E (pt) 2015-09-15
EP2450446B1 (en) 2015-04-29
TWI657141B (zh) 2019-04-21
EP2061889B1 (en) 2014-04-23
HK1203545A1 (en) 2015-10-30
ES2543907T3 (es) 2015-08-25
TWI659102B (zh) 2019-05-11

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