PL2450446T3 - Zwiększanie poziomów alkaloidów nikotynowych - Google Patents

Zwiększanie poziomów alkaloidów nikotynowych

Info

Publication number
PL2450446T3
PL2450446T3 PL11187201T PL11187201T PL2450446T3 PL 2450446 T3 PL2450446 T3 PL 2450446T3 PL 11187201 T PL11187201 T PL 11187201T PL 11187201 T PL11187201 T PL 11187201T PL 2450446 T3 PL2450446 T3 PL 2450446T3
Authority
PL
Poland
Prior art keywords
increasing levels
nicotinic alkaloids
alkaloids
nicotinic
levels
Prior art date
Application number
PL11187201T
Other languages
English (en)
Inventor
Takashi Hashimoto
M Kajikawa
Original Assignee
22Nd Century Ltd Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 22Nd Century Ltd Llc filed Critical 22Nd Century Ltd Llc
Publication of PL2450446T3 publication Critical patent/PL2450446T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
PL11187201T 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych PL2450446T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20110187201 EP2450446B1 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids
EP06848676.0A EP2061889B1 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids
PCT/IB2006/004043 WO2007072224A2 (en) 2006-09-13 2006-09-13 Increasing levels of nicotinic alkaloids

Publications (1)

Publication Number Publication Date
PL2450446T3 true PL2450446T3 (pl) 2015-10-30

Family

ID=38189038

Family Applications (3)

Application Number Title Priority Date Filing Date
PL06848676T PL2061889T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych
PL14163682T PL2792750T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych
PL11187201T PL2450446T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL06848676T PL2061889T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych
PL14163682T PL2792750T3 (pl) 2006-09-13 2006-09-13 Zwiększanie poziomów alkaloidów nikotynowych

Country Status (9)

Country Link
EP (4) EP3578661A1 (pl)
JP (1) JP5087777B2 (pl)
ES (3) ES2748823T3 (pl)
HK (1) HK1203545A1 (pl)
HU (1) HUE026819T2 (pl)
PL (3) PL2061889T3 (pl)
PT (1) PT2450446E (pl)
TW (4) TWI657141B (pl)
WO (1) WO2007072224A2 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9102948B2 (en) 2006-11-17 2015-08-11 22Nd Century Limited, Llc Regulating alkaloids
EP2537929B1 (en) * 2010-02-17 2017-04-12 Japan Tobacco, Inc. Plant component regulation factor, and use thereof
CN102258213B (zh) * 2011-02-25 2013-07-17 福州农博士生物技术有限公司 烟丝生产用复合酶菌制剂及其制备方法
WO2013107527A1 (en) * 2012-01-21 2013-07-25 Vib Vzw Novel genes and uses thereof for secondary metabolite production in plants
BR122020000165B1 (pt) 2013-03-01 2023-04-04 North Carolina State University Construção compreendendo molécula de ácido nucleico de fatores de transcrição que regulam biossíntese de nicotina em tabaco, vetor, célula bacteriana transgênica e método de produção de uma planta
KR102851176B1 (ko) * 2018-07-26 2025-08-28 알트리아 클라이언트 서비시즈 엘엘씨 알칼로이드 수준이 변경된 담배 식물 및 제품을 생산하기 위한 pmt 공학에 기초한 조성물 및 방법
CN110452916B (zh) * 2019-09-03 2020-11-10 西南大学 莨菪醛还原酶及其应用
JP2022552261A (ja) 2019-10-10 2022-12-15 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 変化したアルカロイドレベルを有するタバコ植物およびタバコ製品を作製するためのｑｐｔ操作に基づく組成物および方法
CN113073062B (zh) * 2021-04-07 2023-03-31 广西中烟工业有限责任公司 一种复合微生物制剂及其制备方法和应用
EP4130262A4 (en) * 2021-06-21 2024-05-22 KT & G Corporation Plant cells having engineered qpt gene and method for using same

Family Cites Families (33)

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Publication number Priority date Publication date Assignee Title
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
ATE225853T1 (de) 1990-04-12 2002-10-15 Syngenta Participations Ag Gewebe-spezifische promotoren
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
US5852041A (en) 1993-04-07 1998-12-22 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acethylcholine receptors
US5633363A (en) 1994-06-03 1997-05-27 Iowa State University, Research Foundation In Root preferential promoter
US5837876A (en) 1995-07-28 1998-11-17 North Carolina State University Root cortex specific gene promoter
US6135121A (en) 1996-06-28 2000-10-24 Regent Court Technologies Tobacco products having reduced nitrosamine content
US5803081A (en) 1996-06-28 1998-09-08 Regent Court Technologies Tobacco and related products
US6586661B1 (en) * 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
SE9803986D0 (sv) * 1998-11-23 1998-11-23 Pharmacia & Upjohn Ab New compositions
AU2786000A (en) 1999-02-26 2000-09-21 Cropdesign N.V. Method of modifying plant morphology, biochemistry or physiology using cdc25 substrates
US6805134B2 (en) 1999-04-26 2004-10-19 R. J. Reynolds Tobacco Company Tobacco processing
FR2795424B1 (fr) 1999-06-25 2003-12-05 Agronomique Inst Nat Rech Promoteur s'exprimant specifiquement dans les cellules de racines de plantes, vecteurs et cellules hotes recombinantes comprenant un tel promoteur et plantes transgeniques obtenues
US6723896B1 (en) 1999-11-12 2004-04-20 The Rockefeller University Inducible site-specific recombination for the activation and removal of transgenes in transgenic plants
WO2001059086A2 (en) 2000-02-08 2001-08-16 Sakata Seed Corporation Methods and constructs for agrobacterium-mediated plant transformation
JP2004533807A (ja) 2000-11-07 2004-11-11 ノース・キャロライナ・ステイト・ユニヴァーシティ プトレッシン−ｎ−メチルトランスフェラーゼプロモーター
AU2002228901A1 (en) 2000-11-10 2002-05-21 Vector Tobacco (Bermuda) Ltd. Method and product for removing carcinogens from tobacco smoke
WO2003013226A2 (en) 2001-08-09 2003-02-20 Cibus Genetics Non-transgenic herbicide resistant plants
ATE539084T1 (de) 2001-11-07 2012-01-15 Syngenta Participations Ag Promotoren zur regulierung der genexpression in pflanzenwurzeln
US7700834B2 (en) 2001-11-13 2010-04-20 U.S. Smokless Tobacco Company Nicotiana nucleic acid molecules and uses thereof
US7700851B2 (en) 2001-11-13 2010-04-20 U.S. Smokeless Tobacco Company Tobacco nicotine demethylase genomic clone and uses thereof
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
NZ535395A (en) 2002-02-20 2009-01-31 Simplot Co J R Precise plant breeding using plant DNA border like sequences instead of Agrobacterium borders
US7534934B2 (en) 2002-02-20 2009-05-19 J.R. Simplot Company Precise breeding
AU2003230833A1 (en) 2002-04-09 2003-10-27 Vector Tobacco Ltd. Tobacco having reduced nicotine and nitrosamines
PT1578422E (pt) * 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
US20050034365A1 (en) 2003-01-31 2005-02-17 Philip Morris Usa Inc. Spray and/or soil treatment of tobacco to reduce TSNAs
WO2004076625A2 (en) 2003-02-21 2004-09-10 Vector Tobacco Ltd. Method of identifying plant cells transformed with a gene
AU2004266694A1 (en) * 2003-08-19 2005-03-03 22Nd Century Limited, Llc Reduced-exposure tobacco products
US7411112B2 (en) 2003-10-09 2008-08-12 Pioneer Hi-Bred International, Inc. Maize promoter named CRWAQ81
ATE530656T1 (de) 2005-02-23 2011-11-15 Univ North Carolina State Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene.
KR101413122B1 (ko) * 2005-02-28 2014-07-18 22엔디 센츄리 리미티드, 엘엘씨 식물의 니코틴 알칼로이드 수준의 감소

Also Published As

Publication number Publication date
EP2792750A1 (en) 2014-10-22
EP2792750B1 (en) 2019-07-03
EP2061889A2 (en) 2009-05-27
ES2543907T3 (es) 2015-08-25
TW201414834A (zh) 2014-04-16
HUE026819T2 (en) 2016-07-28
HK1169677A1 (en) 2013-02-01
EP2450446B1 (en) 2015-04-29
TW200817509A (en) 2008-04-16
TW201623611A (zh) 2016-07-01
EP3578661A1 (en) 2019-12-11
PL2792750T3 (pl) 2020-02-28
WO2007072224A3 (en) 2008-04-17
EP2061889B1 (en) 2014-04-23
TWI659102B (zh) 2019-05-11
EP2450446A2 (en) 2012-05-09
JP5087777B2 (ja) 2012-12-05
WO2007072224A8 (en) 2009-04-23
PT2450446E (pt) 2015-09-15
JP2010505449A (ja) 2010-02-25
ES2478633T3 (es) 2014-07-22
TWI421341B (zh) 2014-01-01
PL2061889T3 (pl) 2014-11-28
WO2007072224A2 (en) 2007-06-28
ES2748823T3 (es) 2020-03-18
TW201925466A (zh) 2019-07-01
TWI657141B (zh) 2019-04-21
EP2450446A3 (en) 2012-07-11
HK1203545A1 (en) 2015-10-30

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