PL2488551T3 - Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania - Google Patents

Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Info

Publication number
PL2488551T3
PL2488551T3 PL10768878T PL10768878T PL2488551T3 PL 2488551 T3 PL2488551 T3 PL 2488551T3 PL 10768878 T PL10768878 T PL 10768878T PL 10768878 T PL10768878 T PL 10768878T PL 2488551 T3 PL2488551 T3 PL 2488551T3
Authority
PL
Poland
Prior art keywords
monoclonal antibodies
progastrin monoclonal
progastrin
antibodies
monoclonal
Prior art date
Application number
PL10768878T
Other languages
English (en)
Inventor
Julie Pannequin
Laure Boudier
Dominique Joubert
Frédéric HOLLANDE
Original Assignee
Progastrine Et Cancers S.À R.L.
Institut National De La Santé Et De La Recherche Médicale (Inserm)
Centre National De La Recherche Scientifique (Cnrs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43086711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2488551(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Progastrine Et Cancers S.À R.L., Institut National De La Santé Et De La Recherche Médicale (Inserm), Centre National De La Recherche Scientifique (Cnrs) filed Critical Progastrine Et Cancers S.À R.L.
Publication of PL2488551T3 publication Critical patent/PL2488551T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • General Engineering & Computer Science (AREA)
PL10768878T 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania PL2488551T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25262509P 2009-10-16 2009-10-16
EP10768878.0A EP2488551B1 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses
PCT/EP2010/006329 WO2011045080A2 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses

Publications (1)

Publication Number Publication Date
PL2488551T3 true PL2488551T3 (pl) 2019-01-31

Family

ID=43086711

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18185172.6T PL3421493T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania
PL10768878T PL2488551T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL18185172.6T PL3421493T3 (pl) 2009-10-16 2010-10-15 Przeciwciała monoklonalne przeciwko progastrynie i ich zastosowania

Country Status (42)

Country Link
US (7) US9611320B2 (pl)
EP (2) EP3421493B1 (pl)
JP (3) JP5985987B2 (pl)
KR (2) KR20120091221A (pl)
CN (2) CN104628857A (pl)
AP (1) AP2012006262A0 (pl)
AR (1) AR078659A1 (pl)
AU (1) AU2010306119A1 (pl)
BR (1) BR112012008818B1 (pl)
CA (1) CA2777691C (pl)
CL (1) CL2012000914A1 (pl)
CR (1) CR20120184A (pl)
CU (1) CU24196B1 (pl)
CY (1) CY1120913T1 (pl)
DK (1) DK2488551T3 (pl)
EA (2) EA029271B1 (pl)
EC (1) ECSP12011796A (pl)
ES (2) ES2690943T3 (pl)
GE (1) GEP201706604B (pl)
GT (1) GT201200114A (pl)
HN (1) HN2012000708A (pl)
HR (1) HRP20181645T1 (pl)
IL (2) IL219019B (pl)
IN (1) IN2012DN03348A (pl)
LT (1) LT2488551T (pl)
MA (1) MA33747B1 (pl)
MX (1) MX351635B (pl)
NI (1) NI201200054A (pl)
NZ (2) NZ701709A (pl)
PE (1) PE20121649A1 (pl)
PH (1) PH12012500711B1 (pl)
PL (2) PL3421493T3 (pl)
PT (1) PT2488551T (pl)
RS (1) RS57966B1 (pl)
SG (1) SG10201704933PA (pl)
SI (1) SI2488551T1 (pl)
SM (1) SMT201800628T1 (pl)
TN (1) TN2012000159A1 (pl)
TW (1) TWI537002B (pl)
UA (1) UA106771C2 (pl)
WO (1) WO2011045080A2 (pl)
ZA (1) ZA201202642B (pl)

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UA106771C2 (uk) * 2009-10-16 2014-10-10 Ле Лаборатуар Сервьє Моноклональні антитіла до прогастрину та їх використання
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EA028515B1 (ru) * 2010-07-26 2017-11-30 Ле Лаборатуар Сервье Способы и композиции для терапии рака печени
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CA3193501A1 (en) 2015-12-31 2017-07-06 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating gastric cancer
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CA3058267C (en) * 2017-03-30 2023-07-25 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating prostate cancer using progastrin binding molecule
ES2920283T3 (es) * 2017-12-05 2022-08-02 Progastrine Et Cancers S A R L Terapia de combinación entre un anticuerpo antiprogastrina y la inmunoterapia para tratar el cáncer
JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
EP3759492A1 (en) * 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
TWI793238B (zh) * 2018-12-27 2023-02-21 偉喬生醫股份有限公司 體外檢測生物樣品之胃源性蛋白的方法及套組
US20220372125A1 (en) * 2019-10-02 2022-11-24 Aslan Pharmaceuticals Pte. Ltd. Antigen Specific Binding Domains and Antibody Molecules
CN112062846A (zh) * 2020-04-27 2020-12-11 杭州博茵生物技术有限公司 一种g-17单克隆抗体及其应用
CN115785273B (zh) * 2021-09-10 2023-10-31 东莞市朋志生物科技有限公司 一种抗胃蛋白酶原i的抗体及其应用
CN116143920A (zh) * 2022-12-30 2023-05-23 南京岚煜生物科技有限公司 胃泌素17的单克隆抗体及其细胞株的制备方法和应用
EP4509528A1 (en) * 2023-08-16 2025-02-19 Barrelman Biosciences LLC Monoclonal antibodies against veterinary progastrin-like molecules and their uses
CN117567611B (zh) * 2023-11-22 2024-05-14 艾维可生物科技有限公司 抗成熟型胃泌素17的单克隆抗体及其应用

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KR101570404B1 (ko) * 2010-03-24 2015-11-20 르 라보레또레 쎄르비에르 결장직장암 및 위창자암의 예방
EA028515B1 (ru) * 2010-07-26 2017-11-30 Ле Лаборатуар Сервье Способы и композиции для терапии рака печени

Also Published As

Publication number Publication date
NZ701709A (en) 2016-06-24
CY1120913T1 (el) 2019-12-11
HK1178183A1 (zh) 2013-09-06
MX351635B (es) 2017-10-23
EP3421493A1 (en) 2019-01-02
JP5985987B2 (ja) 2016-09-06
BR112012008818A2 (en) 2018-05-22
PT2488551T (pt) 2018-10-31
US20180022802A1 (en) 2018-01-25
TW201119675A (en) 2011-06-16
PH12012500711B1 (en) 2019-04-24
CL2012000914A1 (es) 2012-09-14
IL219019B (en) 2019-05-30
ZA201202642B (en) 2013-06-26
EA201200597A1 (ru) 2012-12-28
EP3421493B1 (en) 2024-01-17
KR101640520B1 (ko) 2016-07-19
TN2012000159A1 (en) 2013-12-12
CR20120184A (es) 2012-08-20
CN104628857A (zh) 2015-05-20
US10377821B2 (en) 2019-08-13
JP2013507138A (ja) 2013-03-04
US20200002413A1 (en) 2020-01-02
EA201791876A1 (ru) 2018-01-31
JP2017212992A (ja) 2017-12-07
RS57966B1 (sr) 2019-01-31
MA33747B1 (fr) 2012-11-01
SG10201704933PA (en) 2017-07-28
CN102791735A (zh) 2012-11-21
WO2011045080A2 (en) 2011-04-21
CA2777691C (en) 2018-02-27
AU2010306119A1 (en) 2012-05-03
LT2488551T (lt) 2018-10-25
EP2488551A2 (en) 2012-08-22
US20170174761A1 (en) 2017-06-22
US9611320B2 (en) 2017-04-04
IL254004B2 (en) 2023-06-01
US10385124B2 (en) 2019-08-20
AP2012006262A0 (en) 2012-06-30
JP6272793B2 (ja) 2018-01-31
PE20121649A1 (es) 2012-12-08
US20220195035A1 (en) 2022-06-23
EA029271B1 (ru) 2018-03-30
US20170306012A1 (en) 2017-10-26
NI201200054A (es) 2012-08-20
US10385126B2 (en) 2019-08-20
CA2777691A1 (en) 2011-04-21
GEP201706604B (en) 2017-01-25
ECSP12011796A (es) 2012-06-29
AR078659A1 (es) 2011-11-23
CN102791735B (zh) 2016-05-18
CU20120060A7 (es) 2013-04-19
CU24196B1 (es) 2016-09-30
KR20150082672A (ko) 2015-07-15
PL3421493T3 (pl) 2024-04-29
SMT201800628T1 (it) 2019-01-11
EP3421493C0 (en) 2024-01-17
HN2012000708A (es) 2015-06-22
BR112012008818B1 (pt) 2021-10-19
EP2488551B1 (en) 2018-07-25
PH12012500711A1 (en) 2012-11-12
MX2012004400A (es) 2012-06-27
US20110117086A1 (en) 2011-05-19
ES2973217T3 (es) 2024-06-19
WO2011045080A3 (en) 2011-07-07
KR20120091221A (ko) 2012-08-17
US11299542B2 (en) 2022-04-12
ES2690943T3 (es) 2018-11-23
IL254004A0 (en) 2017-10-31
JP2015145380A (ja) 2015-08-13
US10385125B2 (en) 2019-08-20
SI2488551T1 (sl) 2019-01-31
HRP20181645T1 (hr) 2018-12-14
DK2488551T3 (en) 2018-10-08
NZ599971A (en) 2014-12-24
UA106771C2 (uk) 2014-10-10
GT201200114A (es) 2014-08-11
IN2012DN03348A (pl) 2015-10-23
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IL219019A0 (en) 2012-06-28

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