PL2519505T3 - Trzeciorzędowe pochodne 8- hydroksychinolino-7-karboksyamidu i ich zastosowania - Google Patents

Trzeciorzędowe pochodne 8- hydroksychinolino-7-karboksyamidu i ich zastosowania

Info

Publication number
PL2519505T3
PL2519505T3 PL10800763T PL10800763T PL2519505T3 PL 2519505 T3 PL2519505 T3 PL 2519505T3 PL 10800763 T PL10800763 T PL 10800763T PL 10800763 T PL10800763 T PL 10800763T PL 2519505 T3 PL2519505 T3 PL 2519505T3
Authority
PL
Poland
Prior art keywords
hydroxyquinoline
tertiary
applications
carboxamide derivatives
carboxamide
Prior art date
Application number
PL10800763T
Other languages
English (en)
Inventor
Stefania Gagliardi
Sordo Simone Del
Federico Mailland
Michela Legora
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42026678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2519505(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of PL2519505T3 publication Critical patent/PL2519505T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
PL10800763T 2009-12-29 2010-12-28 Trzeciorzędowe pochodne 8- hydroksychinolino-7-karboksyamidu i ich zastosowania PL2519505T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09180902A EP2345643A1 (en) 2009-12-29 2009-12-29 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
PCT/EP2010/070790 WO2011080264A1 (en) 2009-12-29 2010-12-28 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
EP10800763.4A EP2519505B1 (en) 2009-12-29 2010-12-28 Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof

Publications (1)

Publication Number Publication Date
PL2519505T3 true PL2519505T3 (pl) 2015-11-30

Family

ID=42026678

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10800763T PL2519505T3 (pl) 2009-12-29 2010-12-28 Trzeciorzędowe pochodne 8- hydroksychinolino-7-karboksyamidu i ich zastosowania

Country Status (37)

Country Link
US (1) US8729098B2 (pl)
EP (2) EP2345643A1 (pl)
JP (1) JP5808754B2 (pl)
KR (1) KR101666505B1 (pl)
CN (2) CN105384685A (pl)
AU (1) AU2010338267B2 (pl)
BR (1) BR112012015728A2 (pl)
CA (1) CA2783213C (pl)
CL (1) CL2012001757A1 (pl)
CY (1) CY1116493T1 (pl)
DK (1) DK2519505T3 (pl)
DO (1) DOP2012000186A (pl)
EA (1) EA025563B1 (pl)
EC (1) ECSP12012007A (pl)
ES (1) ES2540327T3 (pl)
GE (1) GEP20156244B (pl)
GT (1) GT201200216A (pl)
HR (1) HRP20150749T1 (pl)
HU (1) HUE027220T2 (pl)
IL (1) IL220427A (pl)
MA (1) MA33829B1 (pl)
MX (1) MX2012007748A (pl)
MY (1) MY161869A (pl)
NI (1) NI201200114A (pl)
NZ (1) NZ600788A (pl)
PE (1) PE20130179A1 (pl)
PH (1) PH12012501326A1 (pl)
PL (1) PL2519505T3 (pl)
PT (1) PT2519505E (pl)
RS (1) RS54096B1 (pl)
SG (1) SG181586A1 (pl)
SI (1) SI2519505T1 (pl)
SM (1) SMT201500182B (pl)
TN (1) TN2012000320A1 (pl)
UA (1) UA107949C2 (pl)
WO (1) WO2011080264A1 (pl)
ZA (1) ZA201204347B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2817291A1 (en) * 2012-02-24 2014-12-31 F. Hoffmann-La Roche AG Antiviral compounds
US9751838B2 (en) 2012-10-02 2017-09-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Tetrahydroquinoline derivatives and their use as Epac inhibitors
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
US11746815B2 (en) 2020-09-22 2023-09-05 Milwaukee Electric Tool Corporation Staple and staple collation
USD976093S1 (en) 2020-09-22 2023-01-24 Milwaukee Electric Tool Corporation Staple collation
US12162125B2 (en) 2020-10-30 2024-12-10 Milwaukee Electric Tool Corporation Powered fastener driver

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US326328A (en) 1885-09-15 Broiler
US326330A (en) 1885-09-15 Harness-support
DE540842C (de) 1930-08-06 1931-12-28 Chinosol Fabrik Akt Ges Verfahren zur Darstellung der 8-Acetyloxychinolin-7-carbonsaeure
HUP9801630A2 (hu) 1995-04-08 1998-11-30 Basf Aktiengesellschaft Kinolinszármazékokból és citokróm B/C inhibitorokból készített szinergikus fungicid készítmények
EP0869793A4 (en) * 1995-11-13 1999-02-03 Smithkline Beecham Corp HEMOREGULATORY COMPOUNDS
US6310211B1 (en) 1996-09-10 2001-10-30 Pharmacia & Upjohn Company 8-hydroxy-7-substituted quinolines as anti-viral agents
US6525042B1 (en) * 1997-09-30 2003-02-25 Daiichi Pharmaceutical Co., Ltd. Sulfonyl derivatives
JP2001294572A (ja) * 2000-02-09 2001-10-23 Dai Ichi Seiyaku Co Ltd 新規スルホニル誘導体
AU1532802A (en) 2000-10-12 2002-04-22 Merck & Co Inc Aza- and polyaza-naphthalenyl-carboxamides useful as hiv integrase inhibitors
ATE430745T1 (de) 2000-10-12 2009-05-15 Merck & Co Inc Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase
IL157638A0 (en) 2001-03-01 2004-03-28 Shionogi & Co Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity
DE60322920D1 (de) 2002-08-13 2008-09-25 Shionogi & Co Heterocyclische verbindungen mit hiv-integrase-hemmender wirkung
EP1669348A4 (en) * 2003-09-30 2009-03-11 Eisai R&D Man Co Ltd NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
FR2889192A1 (fr) * 2005-07-27 2007-02-02 Cytomics Systems Sa Composes antifongiques, compositions contenant ces composes et leurs utilisations
US20090325948A1 (en) * 2006-07-26 2009-12-31 Timothy Brian Hurley Inhibitors of undecaprenyl pyrophosphate synthase
WO2009140215A2 (en) * 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
PT2499139E (pt) * 2009-11-10 2014-02-10 Pfizer Inibidores de n1-pirazolospirocetona acetil-coa carboxilase
WO2011075630A1 (en) * 2009-12-18 2011-06-23 Incyte Corporation Substituted fused aryl and heteroaryl derivatives as pi3k inhibitors
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents

Also Published As

Publication number Publication date
EP2519505B1 (en) 2015-05-27
AU2010338267B2 (en) 2014-03-27
RS54096B1 (sr) 2015-10-30
HK1178526A1 (en) 2013-09-13
TN2012000320A1 (en) 2013-12-12
SI2519505T1 (sl) 2015-08-31
EA025563B1 (ru) 2017-01-30
GEP20156244B (en) 2015-02-10
IL220427A (en) 2015-04-30
DOP2012000186A (es) 2013-01-15
PE20130179A1 (es) 2013-02-24
EP2345643A1 (en) 2011-07-20
CA2783213C (en) 2017-09-12
DK2519505T3 (en) 2015-06-29
CY1116493T1 (el) 2017-03-15
PH12012501326A1 (en) 2015-04-01
EA201270670A1 (ru) 2013-03-29
KR20120101563A (ko) 2012-09-13
CN105384685A (zh) 2016-03-09
AU2010338267A1 (en) 2012-07-19
MA33829B1 (fr) 2012-12-03
CL2012001757A1 (es) 2013-03-22
NZ600788A (en) 2013-08-30
SG181586A1 (en) 2012-07-30
EP2519505A1 (en) 2012-11-07
ECSP12012007A (es) 2012-08-31
CA2783213A1 (en) 2011-07-07
SMT201500182B (it) 2015-09-07
HUE027220T2 (hu) 2016-10-28
BR112012015728A2 (pt) 2019-09-24
ES2540327T3 (es) 2015-07-09
PT2519505E (pt) 2015-09-03
GT201200216A (es) 2014-12-26
AU2010338267A2 (en) 2012-07-26
HRP20150749T1 (hr) 2015-08-14
JP2013515755A (ja) 2013-05-09
JP5808754B2 (ja) 2015-11-10
CN102686566A (zh) 2012-09-19
UA107949C2 (xx) 2015-03-10
KR101666505B1 (ko) 2016-10-14
NI201200114A (es) 2013-04-22
MY161869A (en) 2017-05-15
US20120309751A1 (en) 2012-12-06
MX2012007748A (es) 2012-08-03
WO2011080264A1 (en) 2011-07-07
ZA201204347B (en) 2013-09-25
US8729098B2 (en) 2014-05-20

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