PL2540820T3 - Środki i sposoby wpływania na stabilność komórek wytwarzających przeciwciała - Google Patents
Środki i sposoby wpływania na stabilność komórek wytwarzających przeciwciałaInfo
- Publication number
- PL2540820T3 PL2540820T3 PL12175198T PL12175198T PL2540820T3 PL 2540820 T3 PL2540820 T3 PL 2540820T3 PL 12175198 T PL12175198 T PL 12175198T PL 12175198 T PL12175198 T PL 12175198T PL 2540820 T3 PL2540820 T3 PL 2540820T3
- Authority
- PL
- Poland
- Prior art keywords
- influencing
- stability
- methods
- producing cells
- antibody producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/231—Interleukin-10 (IL-10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2321—Interleukin-21 (IL-21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/NL2005/000848 WO2007067032A1 (en) | 2005-12-09 | 2005-12-09 | Means and methods for influencing the stability of cells |
| EP06076211 | 2006-06-12 | ||
| EP12175198.6A EP2540820B1 (en) | 2005-12-09 | 2006-12-08 | Means and methods for influencing the stability of antibody producing cells |
| EP06824300.5A EP1974017B2 (en) | 2005-12-09 | 2006-12-08 | Means and methods for influencing the stability of antibody producing cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2540820T3 true PL2540820T3 (pl) | 2018-05-30 |
Family
ID=37714656
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12175198T PL2540820T3 (pl) | 2005-12-09 | 2006-12-08 | Środki i sposoby wpływania na stabilność komórek wytwarzających przeciwciała |
| PL06824300.5T PL1974017T5 (pl) | 2005-12-09 | 2006-12-08 | Środki i sposoby do wpływania na stabilność komórek wytwarzających przeciwciała |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06824300.5T PL1974017T5 (pl) | 2005-12-09 | 2006-12-08 | Środki i sposoby do wpływania na stabilność komórek wytwarzających przeciwciała |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9127251B2 (pl) |
| EP (3) | EP3327117A1 (pl) |
| JP (2) | JP5753339B2 (pl) |
| AU (2) | AU2006323315B2 (pl) |
| BR (2) | BRPI0619579B8 (pl) |
| CA (2) | CA2633157C (pl) |
| DK (2) | DK2540820T3 (pl) |
| ES (2) | ES2444465T5 (pl) |
| FI (1) | FI1974017T4 (pl) |
| HU (1) | HUE037580T2 (pl) |
| NZ (3) | NZ592159A (pl) |
| PL (2) | PL2540820T3 (pl) |
| PT (2) | PT2540820T (pl) |
| WO (1) | WO2007067046A1 (pl) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0619579B8 (pt) | 2005-12-09 | 2022-01-25 | Academisch Medisch Centrum Bij De Univ Van Amsterdam | Métodos para aumentar a expectativa de vida replicativa e/ou estabilidade de uma célula produtora de anticorpo, para expressar um gene de uma célula b codificando a cadeia pesada de ig e/ou cadeia leve de ig, para produzir linhagem de células b, para obter anticorpos, e, método ex vivo para produzir anticorpos capazes de especificamente ligar um antígeno de interesse |
| US9005974B2 (en) | 2005-12-09 | 2015-04-14 | Academish Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| JP5205597B2 (ja) * | 2007-06-01 | 2013-06-05 | 静岡県 | 1細胞レベルでの抗体遺伝子の解析・同定方法 |
| AU2008284015B2 (en) * | 2007-08-03 | 2014-05-15 | Musc Foundation For Research Development | Human monoclonal antibodies and methods for producing the same |
| EP2307453A1 (en) * | 2008-06-16 | 2011-04-13 | University Of Zurich | Method of providing immunoglobulin secreting b lymphocytes and human antibodies |
| WO2010130636A1 (en) | 2009-05-11 | 2010-11-18 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof |
| DK2454283T3 (en) | 2009-07-15 | 2018-05-07 | Aimm Therapeutics Bv | METHODS AND PROCEDURES FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| CN102770529B (zh) | 2009-11-17 | 2018-06-05 | Musc研究发展基金会 | 针对人核仁素的人单克隆抗体 |
| SI2400298T1 (sl) * | 2010-05-28 | 2013-11-29 | F. Hoffmann-La Roche Ag | Postopek kultivacije posamezne B-celice in izdelava specifičnih protiteles |
| DK2646466T3 (en) | 2010-12-02 | 2017-06-06 | Aimm Therapeutics Bv | METHODS AND METHODS FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES |
| JP6325451B2 (ja) | 2011-12-02 | 2018-05-16 | アイム・セラピューティクス・べー・フェー | A型インフルエンザに特異的な抗体 |
| US10017739B2 (en) * | 2012-09-06 | 2018-07-10 | Duke University | Methods of expanding and assessing B cells and using expanded B cells to treat disease |
| CA2906674C (en) | 2013-03-14 | 2023-01-10 | Immusoft Corporation | Methods for in vitro memory b cell differentiation and transduction with vsv-g pseudotyped viral vectors |
| CN113072644A (zh) | 2013-12-17 | 2021-07-06 | 埃姆医疗有限公司 | 抵抗骨髓增生障碍或淋巴组织增生障碍的手段和方法 |
| WO2015099534A1 (en) | 2013-12-24 | 2015-07-02 | Aimm Therapeutics B.V. | Ex vivo antibody production |
| EP3099709B1 (en) | 2014-01-31 | 2019-12-25 | AIMM Therapeutics B.V. | Means and methods for producing stable antibodies |
| EP3152569B1 (en) * | 2014-06-05 | 2020-06-10 | AIMM Therapeutics B.V. | Means and methods for determining t cell recognition |
| JP6684211B2 (ja) | 2014-07-02 | 2020-04-22 | 学校法人東京理科大学 | B細胞集団の製造方法 |
| EP3234107B1 (en) * | 2014-12-19 | 2022-09-14 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
| ES2959608T3 (es) * | 2015-04-03 | 2024-02-27 | Dana Farber Cancer Inst Inc | Composición y métodos de edición del genoma de células B |
| US11124766B2 (en) | 2015-06-12 | 2021-09-21 | Emory University | Growth and survival compositions for cells capable of producing antibodies and methods related thereto |
| TWI751110B (zh) | 2015-06-24 | 2022-01-01 | 荷蘭商科林生物醫療有限責任公司 | Aml抗原及其用途 |
| US11136407B2 (en) | 2016-01-08 | 2021-10-05 | Aimm Therapeutics B.V. | Therapeutic anti-CD9 antibody |
| CN110494565A (zh) | 2016-12-02 | 2019-11-22 | 朱诺治疗学股份有限公司 | 工程化b细胞及相关组合物和方法 |
| US10908168B2 (en) | 2017-01-31 | 2021-02-02 | Vanderbilt University | Generation of human allergen- and helminth-specific IgE monoclonal antibodies for diagnostic and therapeutic use |
| US11125757B2 (en) | 2017-05-26 | 2021-09-21 | Emory University | Methods of culturing and characterizing antibody secreting cells |
| EP3720878A1 (en) * | 2017-12-05 | 2020-10-14 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to modulate antibody production |
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| US4997764A (en) * | 1987-04-23 | 1991-03-05 | New York University | Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors |
| AU636573B2 (en) | 1988-02-26 | 1993-05-06 | Worcester Foundation For Biomedical Research, Inc. | Inhibition of htlv-iii by exogenous oligonucleotides |
| US5866757A (en) * | 1992-06-02 | 1999-02-02 | Yeda Research And Development Co. Ltd. | Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems |
| WO1994007367A1 (en) * | 1992-09-29 | 1994-04-14 | Apollon, Inc. | Anti-viral oligomers that bind polypurine tracts of single-stranded rna or rna-dna hybrids |
| PL308261A1 (en) | 1992-10-05 | 1995-07-24 | Hybridon | Oligonucleotide exhibiting therapeutic effect in respect to hiv and pharmaceutical agent containing it |
| WO1994017086A1 (en) | 1993-01-25 | 1994-08-04 | Apollon, Inc. | Gene regulation by targeting putative intramolecular triple helix |
| US5550019A (en) | 1993-05-26 | 1996-08-27 | La Jolla Cancer Research Foundation | Methods of identifying compounds which alter apoptosis |
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| AU679120B2 (en) | 1993-09-03 | 1997-06-19 | Systemix, Inc. | Genetically modified human hematopoietic stem cells and their progeny |
| US6265556B1 (en) * | 1994-12-02 | 2001-07-24 | The Burnham Institute | Nucleic acid encoding CD40 associated proteins |
| GB9425060D0 (en) | 1994-12-13 | 1995-02-08 | Univ Birmingham | Carcinoma treatment |
| US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
| US6001558A (en) * | 1997-06-25 | 1999-12-14 | Ortho Clinical Diagnostics, Inc. | Amplification and detection of HIV-1 and/or HIV 2 |
| DE60035515T2 (de) * | 1999-09-08 | 2008-04-17 | GeneTrol Biotherapeutics, Inc., Oakland | Hohe zytokinproduktion mit verbesserter zelllebensfähigkeit |
| EP1083230A1 (en) * | 1999-09-10 | 2001-03-14 | Academisch Medisch Centrum Amsterdam | Viral replicons and viruses dependent on inducing agents |
| US7122180B2 (en) * | 2000-10-23 | 2006-10-17 | Children's Medical Center Corporation | DNA vectors containing mutated HIV proviruses |
| US20030175950A1 (en) | 2001-05-29 | 2003-09-18 | Mcswiggen James A. | RNA interference mediated inhibition of HIV gene expression using short interfering RNA |
| WO2003050262A2 (en) | 2001-12-10 | 2003-06-19 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
| US20050009180A1 (en) * | 2001-12-10 | 2005-01-13 | Lili Yang | Method for the generation of antigen-specific lymphocytes |
| US8318487B2 (en) * | 2001-12-18 | 2012-11-27 | Cancer Research Technology Limited | Materials and methods relating to the production and maintenance of cell lines |
| JP4238138B2 (ja) * | 2001-12-22 | 2009-03-11 | 4−アンチボディ アーゲー | 遺伝的に修飾された脊椎動物前駆体リンパ球の生成方法及び異種結合タンパク質の産生を目的としたその使用。 |
| WO2003079757A2 (en) | 2002-03-20 | 2003-10-02 | Massachusetts Institute Of Technology | Hiv therapeutic |
| JP2004121237A (ja) * | 2002-09-05 | 2004-04-22 | Japan Science & Technology Agency | 体外免疫末梢血リンパ球を用いた抗原特異的抗体 |
| AU2002343870A1 (en) * | 2002-11-07 | 2004-06-07 | Kumamoto Technology And Industry Foundation | Transgenic mammal carrying ganp and utilization thereof |
| GB2398783A (en) | 2003-02-26 | 2004-09-01 | Antonio Lanzavecchia | A method for producing immortalised human B memory lymphocytes |
| CA2518371A1 (en) | 2003-03-14 | 2004-09-30 | Wyeth | Antibodies against human il-21 receptor and uses therefor |
| SG148143A1 (en) | 2003-11-04 | 2008-12-31 | Novartis Vaccines & Diagnostic | Antagonist anti-cd40 monoclonal antibodies and methods for their use |
| US7993919B2 (en) | 2003-11-19 | 2011-08-09 | The United States Of America As Represented By The Department Of Health And Human Services | Method of inducing memory B cell development and terminal differentiation |
| GB0327384D0 (en) | 2003-11-25 | 2003-12-31 | Queen Mary & Westfield College | Gene therapy |
| US20050238626A1 (en) | 2004-04-01 | 2005-10-27 | Lili Yang | Antigen specific T cell therapy |
| WO2005123923A2 (en) | 2004-06-17 | 2005-12-29 | Wolfgang Hillen | Inducer specific tetracycline repressor proteins and methods of use thereof |
| EP1627563A1 (en) * | 2004-08-10 | 2006-02-22 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Means and methods for producing a stabilized cell of interest |
| EP1647595A1 (en) * | 2004-10-15 | 2006-04-19 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Nucleic acids against viruses, in particular HIV |
| US7393923B2 (en) * | 2004-11-08 | 2008-07-01 | The Regents Of The University Of California | Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same |
| US8337851B2 (en) | 2005-05-18 | 2012-12-25 | Novartis Ag | Methods of monitoring the efficacy of anti-CD40 antibodies in treating a subject for a CD40-expressing cancer |
| WO2006132524A1 (en) | 2005-06-06 | 2006-12-14 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for generating a t cell against an antigen of interest. |
| EP1954811B1 (en) | 2005-11-17 | 2011-06-08 | TET Systems GmbH & Co. KG | Inducible expression systems |
| BRPI0619579B8 (pt) | 2005-12-09 | 2022-01-25 | Academisch Medisch Centrum Bij De Univ Van Amsterdam | Métodos para aumentar a expectativa de vida replicativa e/ou estabilidade de uma célula produtora de anticorpo, para expressar um gene de uma célula b codificando a cadeia pesada de ig e/ou cadeia leve de ig, para produzir linhagem de células b, para obter anticorpos, e, método ex vivo para produzir anticorpos capazes de especificamente ligar um antígeno de interesse |
| US9005974B2 (en) * | 2005-12-09 | 2015-04-14 | Academish Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| BRPI0807952A2 (pt) * | 2007-02-20 | 2014-06-10 | Anaptysbio Inc | Sistemas de hipermutação somática |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| WO2010113039A1 (en) * | 2009-04-03 | 2010-10-07 | Medical Research Council | Mutants of activation-induced cytidine deaminase (aid) and methods of use |
| DK2454283T3 (en) * | 2009-07-15 | 2018-05-07 | Aimm Therapeutics Bv | METHODS AND PROCEDURES FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES |
| BR112012000953A8 (pt) | 2009-07-15 | 2017-12-26 | Aimm Therapeutics Bv | anticorpos de ligação a bactérias gram-positivas, sequência de ácido nucleico,seus usos e seu método de produção, células isolada ou produtora de anticorpo isolado ou recombinante, composições, e método de isolamento de bactérias |
| US8568726B2 (en) * | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| BR112012008173B1 (pt) | 2009-10-06 | 2021-12-07 | Medimmune Ltd | Anticorpo monoclonal humano recombinante, sintético ou isolado ou uma parte funcional do mesmo que se liga especificamente à proteína f do vírus sincicial respiratório, sequência de ácido nucleico isolada ou um equivalente funcional da mesma, vetor, combinação, composição farmacêutica, usos dos mesmos e método para produzir um anticorpo ou parte funcional do mesmo |
| DK2646466T3 (en) | 2010-12-02 | 2017-06-06 | Aimm Therapeutics Bv | METHODS AND METHODS FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES |
| JP6325451B2 (ja) | 2011-12-02 | 2018-05-16 | アイム・セラピューティクス・べー・フェー | A型インフルエンザに特異的な抗体 |
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2006
- 2006-12-08 BR BRPI0619579A patent/BRPI0619579B8/pt active IP Right Grant
- 2006-12-08 PL PL12175198T patent/PL2540820T3/pl unknown
- 2006-12-08 ES ES06824300T patent/ES2444465T5/es active Active
- 2006-12-08 PT PT121751986T patent/PT2540820T/pt unknown
- 2006-12-08 HU HUE12175198A patent/HUE037580T2/hu unknown
- 2006-12-08 EP EP18150705.4A patent/EP3327117A1/en active Pending
- 2006-12-08 NZ NZ59215906A patent/NZ592159A/xx unknown
- 2006-12-08 CA CA2633157A patent/CA2633157C/en active Active
- 2006-12-08 BR BR122021001906-1A patent/BR122021001906B1/pt active IP Right Grant
- 2006-12-08 WO PCT/NL2006/000625 patent/WO2007067046A1/en not_active Ceased
- 2006-12-08 NZ NZ60007506A patent/NZ600075A/en unknown
- 2006-12-08 JP JP2008544276A patent/JP5753339B2/ja active Active
- 2006-12-08 DK DK12175198.6T patent/DK2540820T3/en active
- 2006-12-08 PT PT06824300T patent/PT1974017E/pt unknown
- 2006-12-08 EP EP06824300.5A patent/EP1974017B2/en active Active
- 2006-12-08 DK DK06824300.5T patent/DK1974017T4/da active
- 2006-12-08 ES ES12175198.6T patent/ES2660899T3/es active Active
- 2006-12-08 AU AU2006323315A patent/AU2006323315B2/en active Active
- 2006-12-08 PL PL06824300.5T patent/PL1974017T5/pl unknown
- 2006-12-08 FI FIEP06824300.5T patent/FI1974017T4/fi active
- 2006-12-08 NZ NZ56954306A patent/NZ569543A/xx unknown
- 2006-12-08 EP EP12175198.6A patent/EP2540820B1/en active Active
- 2006-12-08 US US12/086,328 patent/US9127251B2/en active Active
- 2006-12-08 CA CA3015416A patent/CA3015416C/en active Active
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2013
- 2013-02-05 JP JP2013020744A patent/JP5753547B2/ja active Active
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2014
- 2014-05-19 AU AU2014202709A patent/AU2014202709B2/en active Active
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2015
- 2015-08-26 US US14/836,335 patent/US9822339B2/en active Active
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2017
- 2017-06-02 US US15/612,096 patent/US10273454B2/en active Active
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