PL2561067T3 - Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1) - Google Patents

Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1)

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Publication number
PL2561067T3
PL2561067T3 PL11726973T PL11726973T PL2561067T3 PL 2561067 T3 PL2561067 T3 PL 2561067T3 PL 11726973 T PL11726973 T PL 11726973T PL 11726973 T PL11726973 T PL 11726973T PL 2561067 T3 PL2561067 T3 PL 2561067T3
Authority
PL
Poland
Prior art keywords
amaurose
lca1
leber
raav
congenital
Prior art date
Application number
PL11726973T
Other languages
English (en)
Inventor
Shannon Elizabeth Boye
William W. Hauswirth
Sanford Leon Boye
Original Assignee
Univ Florida
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Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of PL2561067T3 publication Critical patent/PL2561067T3/pl

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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/864—Parvoviral vectors, e.g. parvovirus, densovirus
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/86—Viral vectors
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01002—Guanylate cyclase (4.6.1.2)
    • A—HUMAN NECESSITIES
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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PL11726973T 2010-04-23 2011-04-22 Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1) PL2561067T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32752110P 2010-04-23 2010-04-23
EP11726973.8A EP2561067B1 (en) 2010-04-23 2011-04-22 Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)
PCT/US2011/033669 WO2011133933A2 (en) 2010-04-23 2011-04-22 Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)

Publications (1)

Publication Number Publication Date
PL2561067T3 true PL2561067T3 (pl) 2019-05-31

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PL11726973T PL2561067T3 (pl) 2010-04-23 2011-04-22 Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1)
PL18198722T PL3486320T3 (pl) 2010-04-23 2011-04-22 Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1)

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PL18198722T PL3486320T3 (pl) 2010-04-23 2011-04-22 Kompozycje RAAV-cyklazy guanylanowej i sposoby leczenia wrodzonej amaurozy-1 Lebera (LCA1)

Country Status (28)

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US (3) US9816108B2 (pl)
EP (3) EP3486320B1 (pl)
JP (4) JP5897549B2 (pl)
KR (3) KR20190060881A (pl)
CN (2) CN105821079B (pl)
AU (1) AU2011242527B2 (pl)
BR (1) BR112012026730A8 (pl)
CA (1) CA2796399C (pl)
CL (1) CL2012002969A1 (pl)
CO (1) CO6640236A2 (pl)
CY (1) CY1123008T1 (pl)
DK (2) DK2561067T3 (pl)
EA (2) EA202091105A1 (pl)
ES (2) ES2911185T3 (pl)
HR (1) HRP20190144T1 (pl)
HU (1) HUE041571T2 (pl)
IL (2) IL222651B (pl)
LT (1) LT2561067T (pl)
MX (1) MX351865B (pl)
NZ (1) NZ602897A (pl)
PL (2) PL2561067T3 (pl)
PT (2) PT2561067T (pl)
RS (1) RS58434B1 (pl)
SG (4) SG10201800541SA (pl)
SI (1) SI2561067T1 (pl)
SM (1) SMT201900097T1 (pl)
TR (1) TR201901377T4 (pl)
WO (1) WO2011133933A2 (pl)

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WO2019155833A1 (ja) * 2018-02-07 2019-08-15 学校法人日本医科大学 改良型アデノ随伴ウイルスベクター
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EP3914229A4 (en) * 2019-01-23 2022-11-02 University of Florida Research Foundation, Incorporated Highly efficient transduction and lateral spread in the retina by a novel aav virus enhanced by rational design
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CN115666658A (zh) 2020-04-01 2023-01-31 佛罗里达州大学研究基金会 具有提高的治疗ush1b的安全性的双aav-myo7a载体
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