PL2570415T3 - N-[4-(1H-pirazolo[3,4-b]pirazyn-6-ylo)-fenylo]-sulfonamidy i ich zastosowanie jako farmaceutyki - Google Patents
N-[4-(1H-pirazolo[3,4-b]pirazyn-6-ylo)-fenylo]-sulfonamidy i ich zastosowanie jako farmaceutykiInfo
- Publication number
- PL2570415T3 PL2570415T3 PL11306179T PL11306179T PL2570415T3 PL 2570415 T3 PL2570415 T3 PL 2570415T3 PL 11306179 T PL11306179 T PL 11306179T PL 11306179 T PL11306179 T PL 11306179T PL 2570415 T3 PL2570415 T3 PL 2570415T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrazin
- pyrazolo
- sulfonamides
- pharmaceuticals
- phenyl
- Prior art date
Links
- QALHRKSMKVLJQH-UHFFFAOYSA-N C1=CC(NS(=O)=O)=CC=C1C1=CN=C(C=NN2)C2=N1 Chemical class C1=CC(NS(=O)=O)=CC=C1C1=CN=C(C=NN2)C2=N1 QALHRKSMKVLJQH-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11306179.0A EP2570415B1 (en) | 2011-09-19 | 2011-09-19 | N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2570415T3 true PL2570415T3 (pl) | 2016-01-29 |
Family
ID=46875813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11306179T PL2570415T3 (pl) | 2011-09-19 | 2011-09-19 | N-[4-(1H-pirazolo[3,4-b]pirazyn-6-ylo)-fenylo]-sulfonamidy i ich zastosowanie jako farmaceutyki |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9174993B2 (pl) |
| EP (2) | EP2570415B1 (pl) |
| AR (1) | AR087907A1 (pl) |
| BR (1) | BR112014006207A2 (pl) |
| CY (1) | CY1117006T1 (pl) |
| DK (1) | DK2570415T3 (pl) |
| EA (1) | EA024295B1 (pl) |
| ES (2) | ES2552836T3 (pl) |
| HR (1) | HRP20151183T1 (pl) |
| HU (1) | HUE026072T2 (pl) |
| MX (1) | MX342869B (pl) |
| MY (1) | MY179987A (pl) |
| PL (1) | PL2570415T3 (pl) |
| PT (1) | PT2570415E (pl) |
| SI (1) | SI2570415T1 (pl) |
| TW (1) | TWI577679B (pl) |
| WO (1) | WO2013041502A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102678781B1 (ko) * | 2016-12-07 | 2024-06-27 | 오리모스 테라퓨틱스 씨오., 엘티디. | Sgk 활성을 조절하기 위한 화합물 및 약학 조성물 및 이의 방법 |
| EP3585371B1 (en) * | 2017-02-24 | 2024-07-10 | Indiana University Research and Technology Corporation | Methods of inhibiting serum glucocorticoid induced kinase 1 (sgk1) as a treatment for salt and water balance diseases |
| AU2020290772A1 (en) | 2019-06-14 | 2022-01-06 | Janssen Pharmaceutica Nv | Pyrazine carbamates and their use as GluN2B receptor modulators |
| AU2020291188A1 (en) | 2019-06-14 | 2022-01-20 | Janssen Pharmaceutica Nv | Substituted heteroaromatic Pyrazolo-pyridines and their use as GluN2B receptor modulators |
| SG11202112407PA (en) | 2019-06-14 | 2021-12-30 | Janssen Pharmaceutica Nv | Substituted pyrazolo-pyridine amides and their use as glun2b receptor modulators |
| JP7667097B2 (ja) | 2019-06-14 | 2025-04-22 | ヤンセン ファーマシューティカ エヌ．ベー． | 置換ピラゾロ－ピリジンアミド及びｇｌｕｎ２ｂ受容体調節因子としてのその使用 |
| EP3983413A1 (en) * | 2019-06-14 | 2022-04-20 | Janssen Pharmaceutica NV | Substituted pyrazolo-pyrazines and their use as glun2b receptor modulators |
| BR112021025132A2 (pt) | 2019-06-14 | 2022-01-25 | Janssen Pharmaceutica Nv | Carbamatos de piridina e seu uso como moduladores do receptor glun2b |
| WO2024015055A1 (en) * | 2022-07-13 | 2024-01-18 | Thryv Therapeutics Inc. | Pyrazolo[3,4-d]pyrimidin-6-yl-sulfonamide derivatives for the inhibition of sgk-1 and treatment of cancer |
| CN121219292A (zh) * | 2023-02-14 | 2025-12-26 | 百时美施贵宝公司 | 作为sgk1抑制剂的氨基取代的吡咯并三嗪衍生物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6690240B2 (en) | 2002-01-10 | 2004-02-10 | Cirrus Logic, Inc. | Low-jitter loop filter for a phase-locked loop system |
| AU2004274403A1 (en) | 2003-09-03 | 2005-03-31 | Aventis Pharmaceuticals Inc. | 5-aryl-Pyrazolo(4,3-d)pyrimidines, pyridines, and pyrazines and related compounds |
| DE102004059781A1 (de) | 2004-12-10 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Verwendung der Serum-/Glucocorticoid regulierten Kinase |
| DE102005015255A1 (de) * | 2005-04-04 | 2006-10-05 | Merck Patent Gmbh | Acylhydrazide |
| DE102006043443A1 (de) | 2006-09-15 | 2008-03-27 | Bayer Healthcare Ag | Neue aza-bicyclische Verbindungen und ihre Verwendung |
| DE102007002717A1 (de) * | 2007-01-18 | 2008-07-24 | Merck Patent Gmbh | Heterocyclische Indazolderivate |
| US20130072493A1 (en) | 2011-09-19 | 2013-03-21 | Sanofi | N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS |
| AU2011377409B2 (en) | 2011-09-19 | 2017-05-25 | Sanofi | N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals |
-
2011
- 2011-09-19 PL PL11306179T patent/PL2570415T3/pl unknown
- 2011-09-19 EP EP11306179.0A patent/EP2570415B1/en active Active
- 2011-09-19 SI SI201130651T patent/SI2570415T1/sl unknown
- 2011-09-19 ES ES11306179.0T patent/ES2552836T3/es active Active
- 2011-09-19 DK DK11306179.0T patent/DK2570415T3/en active
- 2011-09-19 HU HUE11306179A patent/HUE026072T2/en unknown
- 2011-09-19 PT PT113061790T patent/PT2570415E/pt unknown
-
2012
- 2012-09-17 AR ARP120103430A patent/AR087907A1/es unknown
- 2012-09-18 BR BR112014006207A patent/BR112014006207A2/pt not_active IP Right Cessation
- 2012-09-18 EA EA201490662A patent/EA024295B1/ru not_active IP Right Cessation
- 2012-09-18 MY MYPI2014000477A patent/MY179987A/en unknown
- 2012-09-18 MX MX2014002736A patent/MX342869B/es active IP Right Grant
- 2012-09-18 ES ES12759725.0T patent/ES2659551T3/es active Active
- 2012-09-18 WO PCT/EP2012/068291 patent/WO2013041502A1/en not_active Ceased
- 2012-09-18 EP EP12759725.0A patent/EP2758399B1/en active Active
- 2012-09-18 TW TW101134075A patent/TWI577679B/zh not_active IP Right Cessation
- 2012-09-18 US US14/345,488 patent/US9174993B2/en active Active
-
2015
- 2015-11-05 HR HRP20151183TT patent/HRP20151183T1/hr unknown
- 2015-11-18 CY CY20151101035T patent/CY1117006T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013041502A1 (en) | 2013-03-28 |
| DK2570415T3 (en) | 2015-11-23 |
| EP2570415A1 (en) | 2013-03-20 |
| TWI577679B (zh) | 2017-04-11 |
| SI2570415T1 (sl) | 2015-12-31 |
| EP2570415A8 (en) | 2013-05-22 |
| EA201490662A1 (ru) | 2014-07-30 |
| MX2014002736A (es) | 2014-05-01 |
| BR112014006207A2 (pt) | 2017-04-11 |
| MX342869B (es) | 2016-10-17 |
| EA024295B1 (ru) | 2016-09-30 |
| MY179987A (en) | 2020-11-19 |
| EP2758399B1 (en) | 2017-11-15 |
| EP2758399A1 (en) | 2014-07-30 |
| TW201329079A (zh) | 2013-07-16 |
| PT2570415E (pt) | 2015-11-23 |
| HRP20151183T1 (hr) | 2015-12-04 |
| EP2570415B1 (en) | 2015-08-26 |
| ES2552836T3 (es) | 2015-12-02 |
| CY1117006T1 (el) | 2017-04-05 |
| AR087907A1 (es) | 2014-04-23 |
| US20140357640A1 (en) | 2014-12-04 |
| ES2659551T3 (es) | 2018-03-16 |
| HUE026072T2 (en) | 2016-05-30 |
| US9174993B2 (en) | 2015-11-03 |
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