PL2605769T3 - Pochodne benzochinonu do leczenia chorób mitochondrialnych oczu - Google Patents

Pochodne benzochinonu do leczenia chorób mitochondrialnych oczu

Info

Publication number
PL2605769T3
PL2605769T3 PL11748898T PL11748898T PL2605769T3 PL 2605769 T3 PL2605769 T3 PL 2605769T3 PL 11748898 T PL11748898 T PL 11748898T PL 11748898 T PL11748898 T PL 11748898T PL 2605769 T3 PL2605769 T3 PL 2605769T3
Authority
PL
Poland
Prior art keywords
mitchondrial
treatment
eye diseases
benzoquinone derivatives
benzoquinone
Prior art date
Application number
PL11748898T
Other languages
English (en)
Inventor
Achim Feurer
Nuri Gueven
Barbara Hoffmann-Enger
Michael Erb
Holger Deppe
Robert Dallmann
Roman Haefeli
Fabrice Heitz
Original Assignee
Santhera Pharmaceuticals (Schweiz) Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santhera Pharmaceuticals (Schweiz) Ag filed Critical Santhera Pharmaceuticals (Schweiz) Ag
Publication of PL2605769T3 publication Critical patent/PL2605769T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11748898T 2010-08-16 2011-08-16 Pochodne benzochinonu do leczenia chorób mitochondrialnych oczu PL2605769T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US37397210P 2010-08-16 2010-08-16
EP10008542 2010-08-16
US201061424978P 2010-12-20 2010-12-20
EP10015842 2010-12-20
US201161473835P 2011-04-11 2011-04-11
EP11003037 2011-04-11

Publications (1)

Publication Number Publication Date
PL2605769T3 true PL2605769T3 (pl) 2017-01-31

Family

ID=45605465

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11748898T PL2605769T3 (pl) 2010-08-16 2011-08-16 Pochodne benzochinonu do leczenia chorób mitochondrialnych oczu

Country Status (12)

Country Link
EP (1) EP2605769B1 (pl)
CY (1) CY1118134T1 (pl)
DK (1) DK2605769T3 (pl)
ES (1) ES2588770T3 (pl)
HR (1) HRP20161407T1 (pl)
HU (1) HUE030595T2 (pl)
PL (1) PL2605769T3 (pl)
PT (1) PT2605769T (pl)
RS (1) RS55173B1 (pl)
SI (1) SI2605769T1 (pl)
SM (1) SMT201600345B (pl)
WO (1) WO2012022468A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2883882A1 (en) * 2012-09-07 2014-03-13 Ptc Therapeutics, Inc. Benzoquinone derivatives for treating oxidative stress disorders
WO2018078922A1 (ja) * 2016-10-24 2018-05-03 国立大学法人福井大学 白内障の予防剤、治療剤、およびこれらを製造するためのhat阻害剤の使用
ES2961580T3 (es) 2017-01-13 2024-03-12 Cellular Res Inc Revestimiento hidrófilo de canales de fluidos
US11365594B2 (en) 2017-01-18 2022-06-21 Schlumberger Technology Corporation Non-stop circulation system for maintaining bottom hole pressure
CN121949079A (zh) 2019-10-04 2026-05-01 康德生物医疗有限公司 治疗线粒体异常疾病的伐替苯醌的醌、氢醌和萘醌类似物
CN115996916B (zh) 2020-04-03 2025-09-23 康德生物医疗有限公司 用于预防和/或治疗包括弗里德赖希共济失调的线粒体疾病的组合物和方法
WO2021211436A1 (en) * 2020-04-13 2021-10-21 Travecta Therapeutics Pte. Ltd. Idebenone compounds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5919930B2 (ja) 1974-05-02 1984-05-09 武田薬品工業株式会社 キノン酸誘導体の製造法
JPS51128932A (en) 1975-04-30 1976-11-10 Takeda Chem Ind Ltd Organic compounds
JPS56150014A (en) 1980-04-21 1981-11-20 Takeda Chem Ind Ltd Antiallergic agent
JPS5877839A (ja) * 1981-11-02 1983-05-11 Takeda Chem Ind Ltd 安定な微細結晶およびその製造法
ATE64921T1 (de) * 1985-04-08 1991-07-15 Takeda Chemical Industries Ltd Benzochinonderivate, ihre herstellung und verwendung.
EP0788793A1 (en) * 1996-02-01 1997-08-13 Takeda Chemical Industries, Ltd. Idebenone for the treatment of dementia
CA2252519A1 (en) * 1996-07-11 1998-01-22 Keisuke Hirai Use of idebenone and analogues against beta amyloid induced cytotoxicity
TWI246421B (en) 1998-12-03 2006-01-01 Alcon Mfg Ltd Use of neurotrophic factor stimulators for the treatment of ophthalmic neurodegenerative diseases
DE602006014514D1 (pl) 2005-03-21 2010-07-08 Santhera Pharmaceuticals Ch
ES2619303T3 (es) 2005-06-01 2017-06-26 Edison Pharmaceuticals, Inc. Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos
EP1891946A1 (en) 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmucosal administration of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone
US20100099775A1 (en) 2008-10-17 2010-04-22 Alpharx Inc. Method for ameliorating of post-anesthetic recovery
US20100129431A1 (en) 2008-11-24 2010-05-27 Alpharx Inc. Idebenone composition for the treatment of neurological disorders
US20100130619A1 (en) 2008-11-24 2010-05-27 Joseph Schwarz Pharmaceutical composition for parenteral administration of idebenone
US20100215725A1 (en) 2009-02-20 2010-08-26 Joseph Schwarz Pharmaceutical composition containing idebenone for the treatment of liver disorders

Also Published As

Publication number Publication date
EP2605769B1 (en) 2016-07-27
WO2012022468A3 (en) 2012-06-28
HUE030595T2 (en) 2017-05-29
WO2012022468A2 (en) 2012-02-23
ES2588770T3 (es) 2016-11-04
SI2605769T1 (sl) 2016-10-28
CY1118134T1 (el) 2017-06-28
DK2605769T3 (en) 2016-10-24
PT2605769T (pt) 2016-11-02
SMT201600345B (it) 2016-11-10
HRP20161407T1 (hr) 2016-12-02
RS55173B1 (sr) 2017-01-31
EP2605769A2 (en) 2013-06-26

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