PL2653468T3 - Bicykliczny związek i jego zastosowania do celów medycznych - Google Patents

Bicykliczny związek i jego zastosowania do celów medycznych

Info

Publication number
PL2653468T3
PL2653468T3 PL13003505T PL13003505T PL2653468T3 PL 2653468 T3 PL2653468 T3 PL 2653468T3 PL 13003505 T PL13003505 T PL 13003505T PL 13003505 T PL13003505 T PL 13003505T PL 2653468 T3 PL2653468 T3 PL 2653468T3
Authority
PL
Poland
Prior art keywords
medical purposes
bicyclic compound
bicyclic
compound
medical
Prior art date
Application number
PL13003505T
Other languages
English (en)
Inventor
Tohru Kambe
Satoshi Nakayama
Kousuke Tani
Shinsaku Yamane
Toru Maruyama
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of PL2653468T3 publication Critical patent/PL2653468T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/902—Method of implanting
    • Y10S623/905—Eye

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Image Processing (AREA)
PL13003505T 2009-07-28 2010-07-27 Bicykliczny związek i jego zastosowania do celów medycznych PL2653468T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009175246 2009-07-28
EP13003505.8A EP2653468B1 (en) 2009-07-28 2010-07-27 Bicyclic Compound and Use Thereof for Medical Purposes
EP10804397.7A EP2460801B1 (en) 2009-07-28 2010-07-27 Bicyclic compound and use thereof for medical purposes

Publications (1)

Publication Number Publication Date
PL2653468T3 true PL2653468T3 (pl) 2016-08-31

Family

ID=43529306

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10804397T PL2460801T3 (pl) 2009-07-28 2010-07-27 Związek bicykliczny i jego zastosowanie do celów medycznych
PL13003505T PL2653468T3 (pl) 2009-07-28 2010-07-27 Bicykliczny związek i jego zastosowania do celów medycznych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL10804397T PL2460801T3 (pl) 2009-07-28 2010-07-27 Związek bicykliczny i jego zastosowanie do celów medycznych

Country Status (20)

Country Link
US (10) US8614340B2 (pl)
EP (2) EP2653468B1 (pl)
JP (3) JP5652397B2 (pl)
KR (1) KR101768235B1 (pl)
CN (1) CN102498105B (pl)
AU (1) AU2010279183B2 (pl)
BR (1) BR112012001797B1 (pl)
CA (1) CA2767083C (pl)
DK (2) DK2460801T3 (pl)
ES (2) ES2500067T3 (pl)
HU (1) HUE028874T2 (pl)
IL (1) IL217342A (pl)
MX (1) MX2012000889A (pl)
NZ (1) NZ597626A (pl)
PL (2) PL2460801T3 (pl)
PT (1) PT2460801E (pl)
RU (1) RU2540330C2 (pl)
TW (1) TWI466877B (pl)
WO (1) WO2011013651A1 (pl)
ZA (1) ZA201200797B (pl)

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JP5835236B2 (ja) * 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
WO2012102355A1 (ja) 2011-01-27 2012-08-02 小野薬品工業株式会社 二環式化合物およびその医薬用途
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JP6569661B2 (ja) * 2014-02-27 2019-09-04 小野薬品工業株式会社 選択的ep2アゴニスト活性を有する化合物
ES2837399T3 (es) * 2015-07-23 2021-06-30 Ono Pharmaceutical Co Derivados de ácido 2-(octahidrociclopenta(b)piran-2-il)1,3-tiazol-4-carboxílico y compuestos relacionados como agonistas de EP2 con actividad reductora de la presión intraocular
KR20220071293A (ko) * 2016-04-01 2022-05-31 리커리엄 아이피 홀딩스, 엘엘씨 에스트로겐 수용체 조절제
WO2018003945A1 (ja) * 2016-06-30 2018-01-04 小野薬品工業株式会社 二環式化合物の製造方法
EP3730138B1 (en) * 2017-12-21 2024-02-14 Santen Pharmaceutical Co., Ltd. Combination of sepetaprost and ripasudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension
JP7247894B2 (ja) * 2017-12-21 2023-03-29 小野薬品工業株式会社 FP作動薬とβ遮断薬を含有する緑内障治療剤
WO2019124489A1 (ja) * 2017-12-21 2019-06-27 参天製薬株式会社 セペタプロストとep2アゴニストとの組み合わせ医薬
CN111689982B (zh) * 2019-03-15 2023-04-07 博瑞生物医药(苏州)股份有限公司 艾日布林中间体及其制备方法
MY206717A (en) * 2019-09-19 2025-01-03 Polyactiva Pty Ltd Biodegradable drug-polymer conjugate
CN113121443B (zh) 2019-12-31 2024-07-09 财团法人工业技术研究院 β-氨基酸衍生物、含其之激酶抑制剂与医药组合物以及其用途
WO2021145356A1 (ja) * 2020-01-15 2021-07-22 参天製薬株式会社 近視の治療、近視の予防および/または近視の進行抑制のための医薬組成物
JPWO2022034909A1 (pl) * 2020-08-13 2022-02-17
CN116947725B (zh) * 2022-04-14 2026-03-27 广州楷石医药有限公司 曲伏前列素的合成方法
TW202404569A (zh) 2022-04-22 2024-02-01 日商參天製藥股份有限公司 含有賽佩普斯特(Sepetaprost)之眼科用組合物
WO2025159135A1 (ja) * 2024-01-24 2025-07-31 参天製薬株式会社 緑内障または高眼圧症に罹患している患者における夜間睡眠時の眼圧を下降させるためのセペタプロストを含有する点眼液

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WO2012102355A1 (ja) 2011-01-27 2012-08-02 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP5835236B2 (ja) 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
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Also Published As

Publication number Publication date
EP2460801A1 (en) 2012-06-06
US20200093781A1 (en) 2020-03-26
US20190111019A1 (en) 2019-04-18
ZA201200797B (en) 2012-10-31
TW201109311A (en) 2011-03-16
US20120122964A1 (en) 2012-05-17
JPWO2011013651A1 (ja) 2013-01-07
JP2016188217A (ja) 2016-11-04
US11617733B2 (en) 2023-04-04
US20250099419A1 (en) 2025-03-27
IL217342A (en) 2016-03-31
JP6149975B2 (ja) 2017-06-21
US20150112079A1 (en) 2015-04-23
US20230190698A1 (en) 2023-06-22
AU2010279183A1 (en) 2012-02-02
US9889114B2 (en) 2018-02-13
RU2540330C2 (ru) 2015-02-10
BR112012001797A2 (pt) 2017-05-16
HUE028874T2 (en) 2017-01-30
US9388157B2 (en) 2016-07-12
HK1170487A1 (en) 2013-03-01
US10940134B2 (en) 2021-03-09
PL2460801T3 (pl) 2014-11-28
US20140073676A1 (en) 2014-03-13
ES2567328T3 (es) 2016-04-21
KR20120038986A (ko) 2012-04-24
US10201520B2 (en) 2019-02-12
US12201603B2 (en) 2025-01-21
IL217342A0 (en) 2012-02-29
DK2653468T3 (en) 2016-06-06
US20210169842A1 (en) 2021-06-10
WO2011013651A1 (ja) 2011-02-03
DK2460801T3 (da) 2014-09-22
ES2500067T3 (es) 2014-09-30
US20180116995A1 (en) 2018-05-03
CN102498105B (zh) 2014-04-02
CA2767083C (en) 2017-05-16
EP2460801A4 (en) 2013-01-02
US8614340B2 (en) 2013-12-24
EP2460801B1 (en) 2014-06-25
MX2012000889A (es) 2012-02-13
US20160287551A1 (en) 2016-10-06
TWI466877B (zh) 2015-01-01
US8962868B2 (en) 2015-02-24
CN102498105A (zh) 2012-06-13
JP5652397B2 (ja) 2015-01-14
KR101768235B1 (ko) 2017-08-14
CA2767083A1 (en) 2011-02-03
JP2015052011A (ja) 2015-03-19
NZ597626A (en) 2013-03-28
EP2653468B1 (en) 2016-02-24
PT2460801E (pt) 2014-08-29
AU2010279183B2 (en) 2015-10-29
BR112012001797B1 (pt) 2020-04-07
EP2653468A1 (en) 2013-10-23
JP5935857B2 (ja) 2016-06-15
RU2012107109A (ru) 2013-09-10

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