PL2695897T3 - Nowe przeciwciało przeciwko ludzkiemu receptorowi il-23 - Google Patents

Nowe przeciwciało przeciwko ludzkiemu receptorowi il-23

Info

Publication number
PL2695897T3
PL2695897T3 PL12767727T PL12767727T PL2695897T3 PL 2695897 T3 PL2695897 T3 PL 2695897T3 PL 12767727 T PL12767727 T PL 12767727T PL 12767727 T PL12767727 T PL 12767727T PL 2695897 T3 PL2695897 T3 PL 2695897T3
Authority
PL
Poland
Prior art keywords
human
receptor antibody
novel anti
novel
antibody
Prior art date
Application number
PL12767727T
Other languages
English (en)
Inventor
Makoto OHORI
Takanori Sasaki
Hiromu Sato
Katsunari Taguchi
Original Assignee
Astellas Pharma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc. filed Critical Astellas Pharma Inc.
Publication of PL2695897T3 publication Critical patent/PL2695897T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL12767727T 2011-04-01 2012-03-30 Nowe przeciwciało przeciwko ludzkiemu receptorowi il-23 PL2695897T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011081982 2011-04-01
EP12767727.6A EP2695897B1 (en) 2011-04-01 2012-03-30 Novel anti-human il-23 receptor antibody
PCT/JP2012/058531 WO2012137676A1 (ja) 2011-04-01 2012-03-30 新規抗ヒトil-23受容体抗体

Publications (1)

Publication Number Publication Date
PL2695897T3 true PL2695897T3 (pl) 2019-08-30

Family

ID=46969077

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12767727T PL2695897T3 (pl) 2011-04-01 2012-03-30 Nowe przeciwciało przeciwko ludzkiemu receptorowi il-23

Country Status (16)

Country Link
US (1) US9556276B2 (pl)
EP (1) EP2695897B1 (pl)
JP (1) JP5971238B2 (pl)
KR (1) KR20140032392A (pl)
CN (2) CN104817641B (pl)
AR (1) AR085824A1 (pl)
BR (1) BR112013024923A2 (pl)
CA (1) CA2831751A1 (pl)
EA (1) EA026119B1 (pl)
ES (1) ES2728438T3 (pl)
MX (1) MX347955B (pl)
PL (1) PL2695897T3 (pl)
PT (1) PT2695897T (pl)
TR (1) TR201908197T4 (pl)
TW (1) TW201249867A (pl)
WO (1) WO2012137676A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2821416B1 (en) * 2012-02-28 2018-10-03 Astellas Pharma Inc. Novel anti-human il-23 receptor antibody
CN104371019B (zh) * 2013-08-13 2019-09-10 鸿运华宁(杭州)生物医药有限公司 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质
FI3088517T3 (fi) 2013-12-26 2023-11-30 Mitsubishi Tanabe Pharma Corp Ihmisen Anti-IL-33 neutraloiva monoklonaalinen vasta-aine
KR102457751B1 (ko) * 2016-03-10 2022-10-21 악셀레론 파마 인코포레이티드 액티빈 타입 2 수용체 결합 단백질 및 이의 용도
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
CN111471655B (zh) * 2020-03-19 2023-07-07 湖州正熙医学检验实验室有限公司 抗人il12/23稳转细胞株及其构建方法和应用
US20250179196A1 (en) * 2021-07-30 2025-06-05 Janssen Biotech, Inc. Materials and methods of making or using il-23r binding proteins
CN113698484B (zh) * 2021-10-13 2023-07-18 浙江博锐生物制药有限公司 抗il-23r抗体及其用途
WO2026058045A1 (en) 2024-09-12 2026-03-19 Takeda Pharmaceutical Company Limited Alpha4beta7 inhibitor and il-23 inhibitor combination therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
PT690132E (pt) 1993-03-11 2004-04-30 Juridical Fou The Chemo Sero T Anticorpo monoclonal anti-hiv
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
EP2395025A1 (en) * 2007-02-28 2011-12-14 Schering Corporation Engineered Anti-IL-23R Antibodies
WO2010027767A1 (en) 2008-08-27 2010-03-11 Schering Corporation Engineered anti-il-23r antibodies
EP2352762A1 (en) * 2008-11-03 2011-08-10 Schering Corporation Inflammatory bowel disease biomarkers and related methods of treatment

Also Published As

Publication number Publication date
TW201249867A (en) 2012-12-16
CN103459426B (zh) 2015-05-13
US20140275490A1 (en) 2014-09-18
MX347955B (es) 2017-05-16
EP2695897A1 (en) 2014-02-12
TR201908197T4 (tr) 2019-06-21
PT2695897T (pt) 2019-06-12
EA026119B1 (ru) 2017-03-31
WO2012137676A1 (ja) 2012-10-11
EP2695897A4 (en) 2015-03-18
BR112013024923A2 (pt) 2016-11-22
JP5971238B2 (ja) 2016-08-17
CN103459426A (zh) 2013-12-18
KR20140032392A (ko) 2014-03-14
EP2695897A9 (en) 2015-10-07
EP2695897B1 (en) 2019-05-01
CA2831751A1 (en) 2012-10-11
CN104817641B (zh) 2018-06-26
EA201391453A1 (ru) 2014-01-30
JPWO2012137676A1 (ja) 2014-07-28
ES2728438T3 (es) 2019-10-24
AR085824A1 (es) 2013-10-30
CN104817641A (zh) 2015-08-05
US9556276B2 (en) 2017-01-31
MX2013011414A (es) 2014-04-14

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