PL2726626T3 - Mikroorganizm do wytwarzania metioniny ze zwiększonym importem glukozy - Google Patents
Mikroorganizm do wytwarzania metioniny ze zwiększonym importem glukozyInfo
- Publication number
- PL2726626T3 PL2726626T3 PL12730555T PL12730555T PL2726626T3 PL 2726626 T3 PL2726626 T3 PL 2726626T3 PL 12730555 T PL12730555 T PL 12730555T PL 12730555 T PL12730555 T PL 12730555T PL 2726626 T3 PL2726626 T3 PL 2726626T3
- Authority
- PL
- Poland
- Prior art keywords
- microorganism
- methionine production
- enhanced glucose
- glucose import
- import
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title 1
- 239000008103 glucose Substances 0.000 title 1
- 230000008676 import Effects 0.000 title 1
- 229930182817 methionine Natural products 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161502528P | 2011-06-29 | 2011-06-29 | |
| EP11305829 | 2011-06-29 | ||
| PCT/EP2012/062674 WO2013001055A1 (en) | 2011-06-29 | 2012-06-29 | A microorganism for methionine production with enhanced glucose import |
| EP12730555.5A EP2726626B1 (en) | 2011-06-29 | 2012-06-29 | A microorganism for methionine production with enhanced glucose import |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2726626T3 true PL2726626T3 (pl) | 2018-05-30 |
Family
ID=47423448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12730555T PL2726626T3 (pl) | 2011-06-29 | 2012-06-29 | Mikroorganizm do wytwarzania metioniny ze zwiększonym importem glukozy |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9506092B2 (pl) |
| EP (1) | EP2726626B1 (pl) |
| JP (1) | JP2014522642A (pl) |
| KR (1) | KR102029819B1 (pl) |
| CN (1) | CN103781913B (pl) |
| AR (1) | AR086790A1 (pl) |
| BR (1) | BR112013033675B1 (pl) |
| ES (1) | ES2654589T3 (pl) |
| MX (1) | MX347843B (pl) |
| MY (1) | MY166543A (pl) |
| PL (1) | PL2726626T3 (pl) |
| WO (1) | WO2013001055A1 (pl) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2632170T3 (es) | 2012-06-18 | 2017-09-11 | Evonik Degussa Gmbh | Microorganismo recombinante para la producción fermentativa de metionina |
| PL3039153T3 (pl) | 2013-08-30 | 2019-02-28 | Evonik Degussa Gmbh | Mikroorganizm do wytwarzania metioniny o ulepszonej aktywności syntazy metioniny i wypływie metioniny |
| WO2015028675A1 (en) * | 2013-08-30 | 2015-03-05 | Metabolic Explorer | A microorganism for methionine production with enhanced methionine efflux |
| US10329591B2 (en) | 2014-09-01 | 2019-06-25 | Evonik Degussa Gmbh | Method and microorganism for methionine production by fermentation with improved methionine efflux |
| EP3050970B1 (en) | 2015-01-28 | 2019-09-18 | Metabolic Explorer | Modified microorganism for optimized production of 1,4-butanediol |
| KR20170128509A (ko) | 2015-03-18 | 2017-11-22 | 바스프 에스이 | 정제 화학약품의 개선된 제조를 위한 재조합 미생물 |
| ES2811337T3 (es) | 2015-04-07 | 2021-03-11 | Metabolic Explorer Sa | Microorganismo modificado para la producción optimizada de 2,4-dihidroxibutirato con eflujo de 2,4- dihidroxibutirato aumentado |
| CN107690482B (zh) | 2015-04-07 | 2022-11-29 | 代谢探索者公司 | 用于2,4-二羟基丁酸的优化生产的经修饰的微生物 |
| BR112018002048A2 (pt) | 2015-08-07 | 2018-09-18 | Evonik Degussa Gmbh | ?micro-organismo geneticamente modificado e método para a produção fermentativa de metionina? |
| KR102771842B1 (ko) | 2015-11-27 | 2025-02-21 | 에보닉 오퍼레이션스 게엠베하 | L-메티오닌을 제조하는 방법 |
| WO2017118871A1 (en) | 2016-01-08 | 2017-07-13 | Metabolic Explorer | Method to produce l-methionine by a fermentative production |
| KR101853961B1 (ko) * | 2016-04-19 | 2018-06-20 | (주)휴맥스 | 포스 입력의 식별 서비스 제공 장치 및 방법 |
| EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
| EP3354742A1 (en) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| WO2019011942A1 (en) | 2017-07-11 | 2019-01-17 | Adisseo France S.A.S. | YEAST PRODUCING METHIONINE |
| EP3470512A1 (en) | 2017-10-10 | 2019-04-17 | Metabolic Explorer | Mutant phosphoserine aminotransferase for the conversion of homoserine into 4-hydroxy-2-ketobutyrate |
| KR102221040B1 (ko) * | 2019-05-09 | 2021-03-03 | 씨제이제일제당 주식회사 | L-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산을 생산하는 방법 |
| WO2023025656A1 (en) | 2021-08-25 | 2023-03-02 | Metabolic Explorer | Dehydrogenase mutants and applications thereof in amino acid synthesis |
| KR20240105456A (ko) | 2021-11-17 | 2024-07-05 | 메타볼릭 익스플로러 | 발린의 개선된 생산을 위한 미생물 및 방법 |
| US20250340828A1 (en) | 2022-03-01 | 2025-11-06 | Metabolic Explorer | Microorganism and method for the improved production of leucine and/or isoleucine |
| WO2024028428A1 (en) | 2022-08-04 | 2024-02-08 | Metabolic Explorer | Microorganism and method for the improved production of serine and/or cysteine |
| CN120769919A (zh) | 2023-03-01 | 2025-10-10 | 湖南利尔生物科技有限公司 | 一种从l-高丝氨酸直接制备l-甲硫氨酸的方法 |
| EP4467640A1 (en) | 2023-05-23 | 2024-11-27 | Metabolic Explorer | Microorganism and method for the improved production of cysteine and/or derivatives thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4110641B2 (ja) | 1998-11-17 | 2008-07-02 | 味の素株式会社 | 発酵法によるｌ−メチオニンの製造法 |
| JP2000157267A (ja) * | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法 |
| WO2002010209A1 (en) | 2000-08-02 | 2002-02-07 | Degussa Ag | Nucleotide sequences which code for the meth gene |
| DE10116518A1 (de) | 2001-04-03 | 2002-10-17 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP1404856B1 (en) * | 2001-07-06 | 2006-07-26 | Degussa AG | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family |
| RU2245919C2 (ru) | 2002-09-06 | 2005-02-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислоты, штамм escherichia coli tdh7δ mlc::cat/pprt614-продуцент l-треонина |
| DE10303571A1 (de) * | 2003-01-30 | 2004-08-12 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| US20060270013A1 (en) | 2003-02-18 | 2006-11-30 | Michel Chateau | Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways |
| DE10314618A1 (de) * | 2003-04-01 | 2004-10-14 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| DE10359594A1 (de) | 2003-12-18 | 2005-07-28 | Basf Ag | PEF-TU-Expressionseinheiten |
| DE102004003411A1 (de) * | 2004-01-23 | 2005-09-01 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| DE102004005836A1 (de) * | 2004-02-06 | 2005-09-15 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| KR100651220B1 (ko) | 2004-06-29 | 2006-11-29 | 씨제이 주식회사 | Ｌ-메씨오닌 생산 균주 및 상기 균주를 이용한ｌ-메씨오닌의 생산방법 |
| DE102004035065A1 (de) | 2004-07-20 | 2006-02-16 | Basf Ag | P-ET-TS-Expressionseinheiten |
| DK2314710T3 (en) * | 2006-01-04 | 2016-06-13 | Metabolic Explorer Sa | A process for the production of methionine by culturing a microorganism modified to enhance the production of cysteine |
| WO2007119576A1 (en) * | 2006-03-23 | 2007-10-25 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family |
| WO2009043372A1 (en) | 2007-10-02 | 2009-04-09 | Metabolic Explorer | Increasing methionine yield |
| ES2424240T3 (es) | 2007-12-18 | 2013-09-30 | Korea Advanced Institute Of Science And Technology | Microorganismo recombinante con capacidad de utilizar sacarosa como fuente de carbono |
| WO2010020290A1 (en) * | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
| AR083468A1 (es) | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
| WO2012090021A1 (en) * | 2010-12-30 | 2012-07-05 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
-
2012
- 2012-06-28 AR ARP120102329A patent/AR086790A1/es unknown
- 2012-06-29 US US14/128,715 patent/US9506092B2/en active Active
- 2012-06-29 CN CN201280042510.4A patent/CN103781913B/zh active Active
- 2012-06-29 MY MYPI2013004653A patent/MY166543A/en unknown
- 2012-06-29 BR BR112013033675-7A patent/BR112013033675B1/pt active IP Right Grant
- 2012-06-29 PL PL12730555T patent/PL2726626T3/pl unknown
- 2012-06-29 KR KR1020147002040A patent/KR102029819B1/ko active Active
- 2012-06-29 JP JP2014517728A patent/JP2014522642A/ja not_active Ceased
- 2012-06-29 WO PCT/EP2012/062674 patent/WO2013001055A1/en not_active Ceased
- 2012-06-29 ES ES12730555.5T patent/ES2654589T3/es active Active
- 2012-06-29 MX MX2013015202A patent/MX347843B/es active IP Right Grant
- 2012-06-29 EP EP12730555.5A patent/EP2726626B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| US20140134680A1 (en) | 2014-05-15 |
| JP2014522642A (ja) | 2014-09-08 |
| CN103781913A (zh) | 2014-05-07 |
| WO2013001055A1 (en) | 2013-01-03 |
| KR102029819B1 (ko) | 2019-10-08 |
| EP2726626A1 (en) | 2014-05-07 |
| KR20140043804A (ko) | 2014-04-10 |
| MX347843B (es) | 2017-05-16 |
| US9506092B2 (en) | 2016-11-29 |
| EP2726626B1 (en) | 2017-11-15 |
| ES2654589T3 (es) | 2018-02-14 |
| MX2013015202A (es) | 2014-02-17 |
| BR112013033675A2 (pt) | 2018-06-19 |
| BR112013033675B1 (pt) | 2021-06-29 |
| AR086790A1 (es) | 2014-01-22 |
| MY166543A (en) | 2018-07-16 |
| CN103781913B (zh) | 2016-02-24 |
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