PL2788349T3 - Inhibitory kinaz - Google Patents

Inhibitory kinaz

Info

Publication number: PL2788349T3
Authority: PL; Poland
Prior art keywords: kinase inhibitors; kinase; inhibitors
Prior art date: 2011-12-09

Application number

PL12809140T

Other languages

English (en)

Inventor

Niel Monique Bodil Van

Nicholas Charles Ray

Lilian Alcaraz

Terry Aaron Panchal

Andrew Stephen Robert Jennings

Elisabetta Armani

Andrew Peter Cridland

Christopher Hurley

Original Assignee

Chiesi Farmaceutici S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-12-09

Filing date

2012-12-05

Publication date

2017-04-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47471708&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2788349(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-12-05 Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.

2017-04-28 Publication of PL2788349T3 publication Critical patent/PL2788349T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/02—Formic acid
- C07C53/06—Salts thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)

PL12809140T 2011-12-09 2012-12-05 Inhibitory kinaz PL2788349T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP11192871		2011-12-09
EP12187931		2012-10-10
EP12809140.2A EP2788349B1 (en)	2011-12-09	2012-12-05	Kinase inhibitors

Publications (1)

Publication Number	Publication Date
PL2788349T3 true PL2788349T3 (pl)	2017-04-28

Family

ID=47471708

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12809140T PL2788349T3 (pl)	2011-12-09	2012-12-05	Inhibitory kinaz

Country Status (34)

Country	Link
US (5)	US8907094B2 (pl)
EP (1)	EP2788349B1 (pl)
JP (1)	JP6128449B2 (pl)
KR (1)	KR101994381B1 (pl)
CN (3)	CN105503861B (pl)
AR (1)	AR089189A1 (pl)
AU (1)	AU2012347350C1 (pl)
BR (1)	BR112014013760A2 (pl)
CA (1)	CA2858447C (pl)
CL (1)	CL2014001486A1 (pl)
CO (1)	CO6970602A2 (pl)
CY (1)	CY1118340T1 (pl)
DK (1)	DK2788349T3 (pl)
EA (1)	EA025268B1 (pl)
ES (1)	ES2612259T3 (pl)
GE (1)	GEP201706735B (pl)
HR (1)	HRP20161714T1 (pl)
HU (1)	HUE029826T2 (pl)
IL (1)	IL232958A (pl)
LT (1)	LT2788349T (pl)
ME (1)	ME02624B (pl)
MX (1)	MX359200B (pl)
MY (1)	MY170656A (pl)
PE (1)	PE20141370A1 (pl)
PH (1)	PH12014501277A1 (pl)
PL (1)	PL2788349T3 (pl)
PT (1)	PT2788349T (pl)
RS (1)	RS55602B1 (pl)
SG (1)	SG11201402985VA (pl)
SI (1)	SI2788349T1 (pl)
TW (1)	TWI618703B (pl)
UA (1)	UA115320C2 (pl)
WO (1)	WO2013083604A1 (pl)
ZA (1)	ZA201404156B (pl)

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UA115320C2 (uk)	2011-12-09	2017-10-25	К'Єзі Фармачеутічі С.П.А.	Інгібітори кінази
MY167216A (en) *	2011-12-09	2018-08-14	Chiesi Farm Spa	Kinase inhibitors
US9458154B2 (en) *	2011-12-09	2016-10-04	Chiesi Farmaceutici S.P.A.	Kinase inhibitors
GB201214750D0 (en)	2012-08-17	2012-10-03	Respivert Ltd	Compounds
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US20150225373A1 (en)	2012-08-29	2015-08-13	Respivert Limited	Kinase inhibitors
EP2890460B1 (en)	2012-08-29	2017-02-22	Respivert Limited	Kinase inhibitors
US9732063B2 (en)	2012-11-16	2017-08-15	Respivert Limited	Kinase inhibitors
WO2014140582A1 (en)	2013-03-14	2014-09-18	Respivert Limited	Kinase inhibitors
AU2014246866B2 (en)	2013-04-02	2018-05-10	Oxular Acquisitions Limited	Kinase inhibitor
EP2981534B1 (en)	2013-04-02	2017-07-19	Topivert Pharma Limited	Kinase inhibitors based upon n-alkyl pyrazoles
RU2015151886A (ru)	2013-06-06	2017-06-08	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Ингибиторы киназ
WO2014194956A1 (en) *	2013-06-06	2014-12-11	Chiesi Farmaceutici S.P.A.	Derivatives of [1, 2, 4] triazolo [4, 3 - a] pyridine as p38 - map kinase inhibitors
EP3004098B1 (en) *	2013-06-06	2017-08-09	Chiesi Farmaceutici S.p.A.	Kinase inhibitors
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CA2934199A1 (en)	2013-12-20	2015-06-25	Respivert Limited	Urea derivatives useful as kinase inhibitors
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MA40774A (fr)	2014-10-01	2017-08-08	Respivert Ltd	Dérivés de diaryle-urée en tant qu'inhibiteurs de kinase p38
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AR107165A1 (es)	2015-12-23	2018-03-28	Chiesi Farm Spa	Inhibidores de quinasa
MA44131A (fr)	2015-12-23	2021-05-26	Chiesi Farm Spa	Dérivés de 1-(3-tert-butyl-2h-pyrazol-5-yl or 5-tert-butyl-isoxaol-3-yl)-3-(4-([1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalenyl) urée et leur utlisation en tant qu'inhibiteurs de p38 mapk
EA201892213A1 (ru)	2016-04-06	2019-05-31	Топайверт Фарма Лимитед	Ингибиторы киназ
US10364245B2 (en) *	2017-06-07	2019-07-30	Chiesi Farmaceutici S.P.A.	Kinase inhibitors
US10342786B2 (en)	2017-10-05	2019-07-09	Fulcrum Therapeutics, Inc.	P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
BR112020006677A2 (pt)	2017-10-05	2020-10-06	Fulcrum Therapeutics, Inc.	uso de inibidores p38 para reduzir a expressão de dux4
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RU2015151886A (ru)	2013-06-06	2017-06-08	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Ингибиторы киназ
WO2014194956A1 (en)	2013-06-06	2014-12-11	Chiesi Farmaceutici S.P.A.	Derivatives of [1, 2, 4] triazolo [4, 3 - a] pyridine as p38 - map kinase inhibitors
EP3004098B1 (en)	2013-06-06	2017-08-09	Chiesi Farmaceutici S.p.A.	Kinase inhibitors

2012
- 2012-12-05 UA UAA201406293A patent/UA115320C2/uk unknown
- 2012-12-05 CN CN201510853733.4A patent/CN105503861B/zh not_active Expired - Fee Related
- 2012-12-05 KR KR1020147018237A patent/KR101994381B1/ko not_active Expired - Fee Related
- 2012-12-05 RS RS20170046A patent/RS55602B1/sr unknown
- 2012-12-05 PL PL12809140T patent/PL2788349T3/pl unknown
- 2012-12-05 SI SI201230806A patent/SI2788349T1/sl unknown
- 2012-12-05 BR BR112014013760A patent/BR112014013760A2/pt not_active Application Discontinuation
- 2012-12-05 LT LTEP12809140.2T patent/LT2788349T/lt unknown
- 2012-12-05 PE PE2014000923A patent/PE20141370A1/es active IP Right Grant
- 2012-12-05 PT PT128091402T patent/PT2788349T/pt unknown
- 2012-12-05 GE GEAP201213495A patent/GEP201706735B/en unknown
- 2012-12-05 ES ES12809140T patent/ES2612259T3/es active Active
- 2012-12-05 MX MX2014006724A patent/MX359200B/es active IP Right Grant
- 2012-12-05 SG SG11201402985VA patent/SG11201402985VA/en unknown
- 2012-12-05 HR HRP20161714TT patent/HRP20161714T1/hr unknown
- 2012-12-05 ME MEP-2016-279A patent/ME02624B/me unknown
- 2012-12-05 HU HUE12809140A patent/HUE029826T2/en unknown
- 2012-12-05 MY MYPI2014001662A patent/MY170656A/en unknown
- 2012-12-05 EA EA201490949A patent/EA025268B1/ru unknown
- 2012-12-05 CN CN201280066480.0A patent/CN104039787B/zh not_active Expired - Fee Related
- 2012-12-05 CA CA2858447A patent/CA2858447C/en not_active Expired - Fee Related
- 2012-12-05 WO PCT/EP2012/074446 patent/WO2013083604A1/en not_active Ceased
- 2012-12-05 EP EP12809140.2A patent/EP2788349B1/en active Active
- 2012-12-05 AU AU2012347350A patent/AU2012347350C1/en not_active Ceased
- 2012-12-05 CN CN201610333320.8A patent/CN105968110B/zh not_active Expired - Fee Related
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- 2012-12-05 JP JP2014545229A patent/JP6128449B2/ja not_active Expired - Fee Related
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- 2012-12-07 AR ARP120104598A patent/AR089189A1/es not_active Application Discontinuation
- 2012-12-07 TW TW101146036A patent/TWI618703B/zh not_active IP Right Cessation
2014
- 2014-06-05 IL IL232958A patent/IL232958A/en active IP Right Grant
- 2014-06-05 CO CO14121392A patent/CO6970602A2/es unknown
- 2014-06-06 ZA ZA2014/04156A patent/ZA201404156B/en unknown
- 2014-06-06 CL CL2014001486A patent/CL2014001486A1/es unknown
- 2014-06-06 PH PH12014501277A patent/PH12014501277A1/en unknown
- 2014-07-14 US US14/330,145 patent/US9145413B2/en not_active Expired - Fee Related
- 2014-10-14 US US14/513,663 patent/US9139584B2/en not_active Expired - Fee Related
2015
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2016
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Also Published As

Publication number	Publication date
MX359200B (es)	2018-09-19
US20140323470A1 (en)	2014-10-30
JP6128449B2 (ja)	2017-05-17
DK2788349T3 (en)	2017-01-30
CN105503861A (zh)	2016-04-20
KR20140105516A (ko)	2014-09-01
CN104039787A (zh)	2014-09-10
HRP20161714T1 (hr)	2017-02-10
SI2788349T1 (sl)	2017-01-31
CN105968110A (zh)	2016-09-28
CY1118340T1 (el)	2017-06-28
US9139584B2 (en)	2015-09-22
PT2788349T (pt)	2017-02-02
TWI618703B (zh)	2018-03-21
US20150080375A1 (en)	2015-03-19
LT2788349T (lt)	2016-12-27
PH12014501277B1 (en)	2014-09-08
MY170656A (en)	2019-08-24
BR112014013760A2 (pt)	2017-06-13
CL2014001486A1 (es)	2014-11-14
CO6970602A2 (es)	2014-06-13
IL232958A (en)	2017-08-31
EP2788349B1 (en)	2016-10-26
AU2012347350C1 (en)	2017-01-19
HUE029826T2 (en)	2017-04-28
MX2014006724A (es)	2014-08-29
TW201336833A (zh)	2013-09-16
US20130150343A1 (en)	2013-06-13
IL232958A0 (en)	2014-08-03
PE20141370A1 (es)	2014-10-17
SG11201402985VA (en)	2014-08-28
RS55602B1 (sr)	2017-06-30
CN105503861B (zh)	2017-08-01
CA2858447A1 (en)	2013-06-13
CN104039787B (zh)	2016-06-29
EP2788349A1 (en)	2014-10-15
CA2858447C (en)	2020-10-27
ZA201404156B (en)	2016-07-27
US8907094B2 (en)	2014-12-09
HK1200828A1 (en)	2015-08-14
CN105968110B (zh)	2018-04-27
US9315503B2 (en)	2016-04-19
PH12014501277A1 (en)	2014-09-08
US9145413B2 (en)	2015-09-29
HK1222647A1 (zh)	2017-07-07
NZ625965A (en)	2016-08-26
EA201490949A1 (ru)	2014-11-28
UA115320C2 (uk)	2017-10-25
EA025268B1 (ru)	2016-12-30
JP2015500260A (ja)	2015-01-05
KR101994381B1 (ko)	2019-06-28
AU2012347350A1 (en)	2014-07-03
ES2612259T3 (es)	2017-05-16
AU2012347350B2 (en)	2016-09-08
ME02624B (me)	2017-06-20
US20160229852A1 (en)	2016-08-11
US9527846B2 (en)	2016-12-27
GEP201706735B (en)	2017-09-25
WO2013083604A1 (en)	2013-06-13
US20150344475A1 (en)	2015-12-03
AR089189A1 (es)	2014-08-06

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PL2710007T3 (pl)	2020-06-01	Inhibitory kinazy
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IL229028A0 (en)	2013-12-31	Kinase inhibitors
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ZA201402164B (en)	2015-04-29	Protein kinase inhibitors
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