PL2794635T3 - Membranowa chromatografia jonowymienna - Google Patents

Membranowa chromatografia jonowymienna

Info

Publication number
PL2794635T3
PL2794635T3 PL12806322T PL12806322T PL2794635T3 PL 2794635 T3 PL2794635 T3 PL 2794635T3 PL 12806322 T PL12806322 T PL 12806322T PL 12806322 T PL12806322 T PL 12806322T PL 2794635 T3 PL2794635 T3 PL 2794635T3
Authority
PL
Poland
Prior art keywords
ion exchange
exchange membrane
membrane chromatography
chromatography
ion
Prior art date
Application number
PL12806322T
Other languages
English (en)
Inventor
Jerome Joseph Bill Jr.
Arick Michael BROWN
Christopher John Dowd
Brooke Ellen Thayer
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47430154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2794635(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL2794635T3 publication Critical patent/PL2794635T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
PL12806322T 2011-12-22 2012-12-18 Membranowa chromatografia jonowymienna PL2794635T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579285P 2011-12-22 2011-12-22
PCT/US2012/070373 WO2013096322A1 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography
EP12806322.9A EP2794635B8 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography

Publications (1)

Publication Number Publication Date
PL2794635T3 true PL2794635T3 (pl) 2019-02-28

Family

ID=47430154

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12806322T PL2794635T3 (pl) 2011-12-22 2012-12-18 Membranowa chromatografia jonowymienna

Country Status (21)

Country Link
US (3) US10364268B2 (pl)
EP (2) EP3492486A1 (pl)
JP (5) JP6605202B2 (pl)
KR (3) KR20200008022A (pl)
CN (2) CN108892706A (pl)
AR (1) AR089362A1 (pl)
AU (3) AU2012355356B2 (pl)
BR (1) BR112014015101A8 (pl)
CA (1) CA2859376C (pl)
ES (1) ES2697676T3 (pl)
HR (1) HRP20181846T1 (pl)
IL (2) IL267585B (pl)
MX (2) MX360453B (pl)
MY (1) MY172426A (pl)
PL (1) PL2794635T3 (pl)
RU (1) RU2648999C2 (pl)
SG (1) SG11201403437TA (pl)
SI (1) SI2794635T1 (pl)
TR (1) TR201815709T4 (pl)
WO (1) WO2013096322A1 (pl)
ZA (2) ZA201404593B (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2794635T3 (pl) * 2011-12-22 2019-02-28 F.Hoffmann-La Roche Ag Membranowa chromatografia jonowymienna
US9951101B2 (en) 2013-12-12 2018-04-24 Emd Millipore Corporation Protein separations using an acrylamide containing filter
US10654933B2 (en) * 2013-12-27 2020-05-19 Chugai Seiyaku Kabushiki Kaisha Method for purifying antibody having low isoelectric point
CN104693303B (zh) * 2015-02-28 2018-03-13 苏州金盟生物技术有限公司 一种蛋白制品中的核酸去除方法
ES2964640T3 (es) 2015-08-13 2024-04-08 Amgen Inc Filtración en profundidad cargada de proteínas de unión al antígeno
GB201711481D0 (en) 2017-07-17 2017-08-30 Ucb Biopharma Sprl Protein purification
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
US10792618B2 (en) 2018-06-19 2020-10-06 Sartorius Stedim Biotech Gmbh Particle separation and/or purification of a fluid
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
US12103949B2 (en) * 2018-08-14 2024-10-01 Bristol-Myers Squibb Company Protein recovery
GB201815405D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules
US12306152B2 (en) 2018-12-21 2025-05-20 Solventum Intellectual Properties Company Method for testing a chromatography device used for ion exchange
AR119264A1 (es) * 2019-06-05 2021-12-09 Genentech Inc Método para reutilización de cromatografía
AU2021210905A1 (en) * 2020-01-24 2022-09-01 Mural Oncology, Inc. Methods of purification
US11416468B2 (en) * 2020-07-21 2022-08-16 International Business Machines Corporation Active-active system index management
CN116425826A (zh) * 2021-12-30 2023-07-14 广州百济神州生物制药有限公司 一种快速纯化质量样品的方法
CN116371011B (zh) * 2023-05-26 2023-08-18 湖南杰萃生物技术有限公司 一种从桑叶中提取黄酮和生物碱的方法
CN117866038B (zh) * 2024-03-11 2024-05-28 北京百力格生物科技有限公司 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法
CN122057257A (zh) * 2026-04-16 2026-05-19 苏州小路生物科技有限公司 一种用于多特异性抗体分步纯化的双入口捕获柱切换装置

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE266710C (pl)
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
JPS6150925A (ja) 1984-08-17 1986-03-13 Toray Ind Inc 抗原または抗体の精製方法
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
ATE121418T1 (de) * 1987-10-23 1995-05-15 Schering Corp Verfahren zur proteinreinigung.
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
JP2749167B2 (ja) 1988-06-21 1998-05-13 ジェネンテク,インコーポレイテッド 心筋梗塞の処置のための方法および治療用組成物
WO1990003430A1 (en) 1988-09-23 1990-04-05 Cetus Corporation Cell culture medium for enhanced cell growth, culture longevity and product expression
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JP2844346B2 (ja) 1989-05-31 1999-01-06 昭 梶 新規ペプチドならびに新規dna
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
EP1260521B1 (en) 1991-08-14 2007-11-21 Genentech Inc. Immunoglobulin variants for specific Fc epsilon receptors
DE69233528T2 (de) 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
CA2372813A1 (en) 1992-02-06 1993-08-19 L.L. Houston Biosynthetic binding protein for cancer marker
CA2140933A1 (en) 1992-08-21 1994-02-22 Paula M. Jardieu Method for treating an lfa-1 mediated disorder
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
JP4057049B2 (ja) 1993-09-21 2008-03-05 ヘモソル インコーポレーテッド 置換クロマトグラフィー法および精製ヘモグロビン産物
EP0733207B1 (en) 1993-12-10 1997-08-27 Genentech, Inc. Methods for diagnosis of allergy and screening of anti-allergy therapeutics
AP660A (en) 1994-01-18 1998-08-18 Genentech Inc A method of treatment of parasitic infection using IgE antagonists.
US5707622A (en) 1994-03-03 1998-01-13 Genentech, Inc. Methods for treating ulcerative colitis
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
CA2222231A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
PT877626E (pt) 1996-01-23 2003-01-31 Univ Vermont And State Agric C Anticorpos anti-cd1s para utilizacao contra icto
CA2242931A1 (en) 1996-01-31 1997-08-07 David Francis Elgar Production of an immunoglobulin enriched fraction from whey protein solutions
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
AU731817C (en) 1996-11-27 2001-11-01 Genentech Inc. Humanized anti-CD11a antibodies
DE69829891T2 (de) 1997-04-07 2005-10-06 Genentech, Inc., South San Francisco Anti-VEGF Antikörper
PT981618E (pt) 1997-05-15 2007-11-23 Genentech Inc ''anticorpo anti-apo-2''
US6054293A (en) 1997-07-08 2000-04-25 The Regents Of The University Of California Semaphorin receptors
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
AR024464A1 (es) 1999-06-25 2002-10-02 Genentech Inc Anticuerpos anti-erbb2 humanizados.
KR100490077B1 (ko) 1999-10-29 2005-05-17 제넨테크, 인크. 항-전립선 줄기세포 항원 (psca) 항체 조성물 및 그의사용 방법
JP2004504330A (ja) 2000-07-13 2004-02-12 インヴィトロジェン コーポレーション 溶解マトリクスを用いてタンパク質およびペプチドの迅速な抽出および単離のための方法および組成物
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
US7321026B2 (en) 2001-06-27 2008-01-22 Skytech Technology Limited Framework-patched immunoglobulins
AU2002325755A1 (en) 2001-09-18 2003-04-01 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
AU2002332130A1 (en) 2001-10-16 2003-04-28 Exelixis, Inc. Msrebps as modifiers of the srebp pathway and methods of use
CA2476675A1 (en) 2001-10-17 2003-04-24 Human Genome Sciences, Inc. Neutrokine-alpha and neutrokine-alpha splice variant
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
CA2476166C (en) 2002-02-14 2011-11-15 Immunomedics, Inc. Anti-cd20 antibodies and fusion proteins thereof and methods of use
KR100944575B1 (ko) 2002-10-17 2010-02-25 젠맵 에이/에스 Cd20에 대한 인간 모노클로날 항체
HUE035898T2 (en) 2002-12-16 2018-05-28 Genentech Inc Immunoglobulin variants and their applications
CN1206240C (zh) * 2003-04-07 2005-06-15 中国科学院生态环境研究中心 高效离子交换膜色谱纯化卵黄蛋白原技术
KR101351122B1 (ko) 2003-05-09 2014-01-14 듀크 유니버시티 Cd20-특이적 항체 및 이를 이용한 방법
AR044388A1 (es) 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
CA2534898A1 (en) 2003-08-08 2005-02-17 Immunomedics, Inc. Bispecific antibodies for inducing apoptosis of tumor and diseased cells
US8147832B2 (en) 2003-08-14 2012-04-03 Merck Patent Gmbh CD20-binding polypeptide compositions and methods
US20080274501A1 (en) * 2007-05-02 2008-11-06 Chenming Zhang Method of purifying acidic proteins expressed in plants
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
AU2008315124B2 (en) 2007-10-26 2012-06-21 Asahi Kasei Chemicals Corporation Method for purifying protein
HUE024877T2 (en) 2007-10-30 2016-02-29 Genentech Inc Antibody purification by cation exchange chromatography
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
HUE066562T2 (hu) 2008-08-14 2024-08-28 Genentech Inc Eljárások szennyezés eltávolítására indigén fehérje kiszorításos ioncserés membrán kromatográfia alkalmazásával
GB0816242D0 (en) 2008-09-05 2008-10-15 Immunobiology Ltd Method of purifying protien complexes
EP4786482A2 (en) 2009-08-06 2026-08-05 F. Hoffmann-La Roche AG Virus filtration methods
BR112012004697B8 (pt) 2009-09-01 2021-05-25 Genentech Inc método para purificar um polipeptídeo compreendendo uma região ch2/ch3
WO2011133886A2 (en) * 2010-04-23 2011-10-27 Genentech, Inc. Production of heteromultimeric proteins
HRP20171095T4 (hr) 2010-05-25 2022-07-22 F. Hoffmann - La Roche Ag Postupci pročišćavanja polipeptida
JP2014531604A (ja) * 2011-10-03 2014-11-27 サッチェム,インコーポレイテッド 疎水性置換クロマトグラフィーのためのアニオン性置換剤分子
PL2794635T3 (pl) * 2011-12-22 2019-02-28 F.Hoffmann-La Roche Ag Membranowa chromatografia jonowymienna
JP5731726B1 (ja) 2014-06-26 2015-06-10 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
AU2012355356B2 (en) 2017-10-12
HRP20181846T1 (hr) 2018-12-28
AR089362A1 (es) 2014-08-20
EP2794635B1 (en) 2018-09-12
US20140348845A1 (en) 2014-11-27
TR201815709T4 (tr) 2018-11-21
ES2697676T3 (es) 2019-01-25
WO2013096322A9 (en) 2013-08-22
MY172426A (en) 2019-11-25
KR20140114834A (ko) 2014-09-29
EP2794635B8 (en) 2018-11-14
EP2794635A1 (en) 2014-10-29
KR102067075B1 (ko) 2020-01-17
CN104125963A (zh) 2014-10-29
JP2021169454A (ja) 2021-10-28
JP7359807B2 (ja) 2023-10-11
BR112014015101A2 (pt) 2017-06-13
US20240247027A1 (en) 2024-07-25
MX360453B (es) 2018-11-01
MX2014007622A (es) 2014-09-22
CN108892706A (zh) 2018-11-27
JP2020040952A (ja) 2020-03-19
US11945837B2 (en) 2024-04-02
IL267585A (en) 2019-08-29
RU2014130017A (ru) 2016-02-10
JP6605202B2 (ja) 2019-11-13
IL267585B (en) 2022-09-01
CN104125963B (zh) 2018-08-17
ZA201903994B (en) 2023-12-20
AU2018200194B2 (en) 2019-11-14
AU2018200194A1 (en) 2018-02-01
KR20200008022A (ko) 2020-01-22
SI2794635T1 (sl) 2018-12-31
US20200102346A1 (en) 2020-04-02
WO2013096322A1 (en) 2013-06-27
CA2859376A1 (en) 2013-06-27
JP2022101557A (ja) 2022-07-06
NZ626949A (en) 2016-11-25
KR20210025692A (ko) 2021-03-09
AU2020201070A1 (en) 2020-03-05
RU2648999C2 (ru) 2018-03-29
SG11201403437TA (en) 2014-07-30
CA2859376C (en) 2022-04-19
EP3492486A1 (en) 2019-06-05
AU2012355356A1 (en) 2014-07-10
IL233158A0 (en) 2014-07-31
IL233158B (en) 2019-07-31
ZA201404593B (en) 2022-12-21
US10364268B2 (en) 2019-07-30
WO2013096322A8 (en) 2014-02-27
HK1203526A1 (en) 2015-10-30
JP7402011B2 (ja) 2023-12-20
JP2015503524A (ja) 2015-02-02
BR112014015101A8 (pt) 2021-06-08
JP2018109024A (ja) 2018-07-12
MX2018013356A (es) 2020-09-14

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