PL2807153T3 - Związki heterocykliczne i sposoby ich zastosowania - Google Patents
Związki heterocykliczne i sposoby ich zastosowaniaInfo
- Publication number
- PL2807153T3 PL2807153T3 PL13741446T PL13741446T PL2807153T3 PL 2807153 T3 PL2807153 T3 PL 2807153T3 PL 13741446 T PL13741446 T PL 13741446T PL 13741446 T PL13741446 T PL 13741446T PL 2807153 T3 PL2807153 T3 PL 2807153T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012900286A AU2012900286A0 (en) | 2012-01-25 | "Methods of treatment or prophylaxis" | |
| PCT/AU2013/000061 WO2013110134A1 (en) | 2012-01-25 | 2013-01-25 | Heterocyclic compounds and methods for their use |
| EP13741446.2A EP2807153B1 (en) | 2012-01-25 | 2013-01-25 | Heterocyclic compounds and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2807153T3 true PL2807153T3 (pl) | 2020-09-07 |
Family
ID=48872832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13741446T PL2807153T3 (pl) | 2012-01-25 | 2013-01-25 | Związki heterocykliczne i sposoby ich zastosowania |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20150011565A1 (pl) |
| EP (1) | EP2807153B1 (pl) |
| JP (2) | JP6258867B2 (pl) |
| CN (1) | CN104470903B (pl) |
| AU (1) | AU2013202973C9 (pl) |
| CA (1) | CA2861231C (pl) |
| ES (1) | ES2798289T3 (pl) |
| NZ (1) | NZ627560A (pl) |
| PL (1) | PL2807153T3 (pl) |
| PT (1) | PT2807153T (pl) |
| WO (1) | WO2013110134A1 (pl) |
| ZA (1) | ZA201405255B (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2621708C2 (ru) | 2011-06-22 | 2017-06-07 | ПУРДЬЮ ФАРМА Эл. Пи. | Антагонисты trpv1, включающие дигидроксигруппу в качестве заместителя, и их применение |
| ES2802251T3 (es) | 2012-01-06 | 2021-01-18 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| ES2798289T3 (es) * | 2012-01-25 | 2020-12-10 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| US9714224B2 (en) | 2013-07-08 | 2017-07-25 | Novartis Ag | Heterocyclic compounds and methods of their use |
| EP3024832B1 (en) | 2013-07-22 | 2018-03-28 | Idorsia Pharmaceuticals Ltd | 1-(piperazin-1-yl)-2-([1,2,4]triazol-1-yl)-ethanone derivatives |
| WO2015063709A1 (en) * | 2013-10-31 | 2015-05-07 | Ranbaxy Laboratories Limited | Process for the preparation of 1-(3-methyl-1-phenyl-1h-pyrazol-5-yl)piperazine |
| WO2016113668A1 (en) | 2015-01-13 | 2016-07-21 | Novartis Ag | Pyrrolidine derivatives as angiotensin ii type 2 antagonists |
| AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| AU2016207988B2 (en) | 2015-01-15 | 2019-08-15 | Idorsia Pharmaceuticals Ltd | Hydroxyalkyl-piperazine derivatives as CXCR3 receptor modulators |
| WO2016142867A1 (en) | 2015-03-12 | 2016-09-15 | Novartis Ag | Heterocyclic compounds and methods for their use |
| CN105503787A (zh) * | 2015-12-31 | 2016-04-20 | 阜阳欣奕华材料科技有限公司 | 一种索非布韦中间体的纯化方法 |
| WO2019040105A2 (en) * | 2017-08-21 | 2019-02-28 | Acadia Pharmaceuticals Inc. | COMPOUNDS, SALTS THEREOF AND METHODS FOR THE TREATMENT OF DISEASES |
| US10710975B2 (en) | 2017-12-15 | 2020-07-14 | Inthera Bioscience AG | Oxopiperazine derivatives |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4400511A (en) * | 1982-05-07 | 1983-08-23 | American Home Products Corporation | 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids |
| EP0398720A3 (en) * | 1989-05-18 | 1991-07-03 | Glaxo Group Limited | Piperazine derivatives |
| US5292726A (en) * | 1991-05-22 | 1994-03-08 | Merck & Co., Inc. | N,N-diacylpiperazines |
| US5344830A (en) * | 1992-12-10 | 1994-09-06 | Merck & Co., Inc. | N,N-diacylpiperazine tachykinin antagonists |
| US5348955A (en) * | 1993-06-22 | 1994-09-20 | Merck & Co., Inc. | N,N-diacylpiperazines |
| US5464788A (en) * | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| WO1998007702A1 (en) * | 1996-08-23 | 1998-02-26 | Kowa Co., Ltd. | Diamide compounds and drugs containing the same |
| PE104798A1 (es) * | 1997-06-17 | 1999-11-06 | Pharmacopeia Inc | Compuestos utiles para la inhibicion de la enzima farnesilo transferasa |
| US5968938A (en) * | 1997-06-18 | 1999-10-19 | Merck & Co., Inc. | Piperazine oxytocin receptor antagonists |
| US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US6951862B2 (en) * | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US7589199B2 (en) * | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
| PL374860A1 (pl) * | 2002-07-09 | 2005-11-14 | Bristol-Myers Squibb Company | Podstawione pochodne heterocykliczne korzystne jako środki przeciwko cukrzycy i otyłości i sposób ich stosowania |
| DE10309005A1 (de) * | 2003-03-01 | 2004-09-09 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Dipetidyl Peptidase (DPPIV) und Neurale Endopeptidase (NEP) inhibieren |
| EP1745042A4 (en) * | 2004-04-09 | 2010-07-14 | Neuromed Pharmaceuticals Ltd | DIARYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS |
| EP2650011A1 (en) * | 2004-12-24 | 2013-10-16 | Spinifex Pharmaceuticals Pty Ltd | Method of treatment or prophylaxis |
| WO2006086609A2 (en) * | 2005-02-10 | 2006-08-17 | Axys Pharmaceuticals, Inc. | Inhibitors of tryptase |
| US20070049578A1 (en) * | 2005-08-24 | 2007-03-01 | Astrazeneca Ab | Cinnamamide compounds as metabotropic glutamate receptor antagonists |
| EP1970373A1 (en) * | 2005-12-02 | 2008-09-17 | Mitsubishi Tanabe Pharma Corporation | Alicyclic heterocyclic compound |
| JP5230595B2 (ja) | 2006-03-20 | 2013-07-10 | スピニフェクス ファーマシューティカルズ ピーティーワイ リミテッド | 炎症性疼痛の治療または予防の方法 |
| WO2007133481A2 (en) * | 2006-05-11 | 2007-11-22 | Neuromed Pharmaceuticals Ltd. | Method for increasing the bioavailability of benzhydryl piperazine containing compounds |
| JP2008031064A (ja) * | 2006-07-27 | 2008-02-14 | Astellas Pharma Inc | ジアシルピペラジン誘導体 |
| JP2009007341A (ja) * | 2007-06-01 | 2009-01-15 | Mitsubishi Tanabe Pharma Corp | 医薬組成物 |
| JP5433690B2 (ja) | 2008-06-25 | 2014-03-05 | ブリストル−マイヤーズ スクイブ カンパニー | 抗−ｈｉｖ薬としてのジケト縮合アゾロピペリジンおよびアゾロピペラジン |
| NZ601383A (en) | 2010-01-19 | 2014-07-25 | Spinifex Pharm Pty Ltd | Methods and compositions for improved nerve conduction velocity |
| ES2802251T3 (es) | 2012-01-06 | 2021-01-18 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| ES2798289T3 (es) * | 2012-01-25 | 2020-12-10 | Novartis Ag | Compuestos heterocíclicos y métodos para su uso |
| JP6073926B2 (ja) | 2012-01-25 | 2017-02-01 | ノバルティス アーゲー | 複素環式化合物およびその使用方法 |
-
2013
- 2013-01-25 ES ES13741446T patent/ES2798289T3/es active Active
- 2013-01-25 EP EP13741446.2A patent/EP2807153B1/en active Active
- 2013-01-25 US US14/373,355 patent/US20150011565A1/en not_active Abandoned
- 2013-01-25 CN CN201380016259.9A patent/CN104470903B/zh active Active
- 2013-01-25 JP JP2014553581A patent/JP6258867B2/ja active Active
- 2013-01-25 AU AU2013202973A patent/AU2013202973C9/en active Active
- 2013-01-25 NZ NZ627560A patent/NZ627560A/en unknown
- 2013-01-25 PT PT137414462T patent/PT2807153T/pt unknown
- 2013-01-25 CA CA2861231A patent/CA2861231C/en active Active
- 2013-01-25 WO PCT/AU2013/000061 patent/WO2013110134A1/en not_active Ceased
- 2013-01-25 PL PL13741446T patent/PL2807153T3/pl unknown
-
2014
- 2014-07-17 ZA ZA2014/05255A patent/ZA201405255B/en unknown
-
2016
- 2016-05-09 US US15/149,641 patent/US9708275B2/en active Active
-
2017
- 2017-10-25 JP JP2017205744A patent/JP2018076297A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015504900A (ja) | 2015-02-16 |
| AU2013202973B2 (en) | 2016-06-02 |
| US20150011565A1 (en) | 2015-01-08 |
| PT2807153T (pt) | 2020-06-18 |
| EP2807153B1 (en) | 2020-03-25 |
| CN104470903B (zh) | 2017-02-22 |
| WO2013110134A1 (en) | 2013-08-01 |
| JP2018076297A (ja) | 2018-05-17 |
| US20160257656A1 (en) | 2016-09-08 |
| EP2807153A4 (en) | 2015-06-10 |
| HK1201533A1 (en) | 2015-09-04 |
| CN104470903A (zh) | 2015-03-25 |
| EP2807153A1 (en) | 2014-12-03 |
| AU2013202973C9 (en) | 2016-12-22 |
| CA2861231A1 (en) | 2013-08-01 |
| ES2798289T3 (es) | 2020-12-10 |
| NZ627560A (en) | 2016-08-26 |
| JP6258867B2 (ja) | 2018-01-10 |
| ZA201405255B (en) | 2019-04-24 |
| US9708275B2 (en) | 2017-07-18 |
| AU2013202973C1 (en) | 2016-11-24 |
| AU2013202973B9 (en) | 2016-11-24 |
| CA2861231C (en) | 2021-04-13 |
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