PL2877170T3 - Wywoływanie arteriogenezy nitrogliceryną - Google Patents
Wywoływanie arteriogenezy nitroglicerynąInfo
- Publication number
- PL2877170T3 PL2877170T3 PL13726197T PL13726197T PL2877170T3 PL 2877170 T3 PL2877170 T3 PL 2877170T3 PL 13726197 T PL13726197 T PL 13726197T PL 13726197 T PL13726197 T PL 13726197T PL 2877170 T3 PL2877170 T3 PL 2877170T3
- Authority
- PL
- Poland
- Prior art keywords
- arteriogenesis
- nitroglycerine
- induction
- Prior art date
Links
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 title 1
- 230000027746 artery morphogenesis Effects 0.000 title 1
- 229960003711 glyceryl trinitrate Drugs 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261653595P | 2012-05-31 | 2012-05-31 | |
| EP12004187.6A EP2668947B1 (en) | 2012-05-31 | 2012-05-31 | Induction of arteriogenesis with a nitric oxide-donor such as nitroglycerin |
| EP13726197.0A EP2877170B1 (en) | 2012-05-31 | 2013-05-29 | Induction of arteriogenesis with nitroglycerine |
| PCT/EP2013/061131 WO2013178715A1 (en) | 2012-05-31 | 2013-05-29 | Induction of arteriogenesis with an no (nitric oxide) donor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2877170T3 true PL2877170T3 (pl) | 2019-11-29 |
Family
ID=46275671
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12004187T PL2668947T3 (pl) | 2012-05-31 | 2012-05-31 | Indukcja arteriogenezy donorem NO, takim jak nitrogliceryna |
| PL13726197T PL2877170T3 (pl) | 2012-05-31 | 2013-05-29 | Wywoływanie arteriogenezy nitrogliceryną |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12004187T PL2668947T3 (pl) | 2012-05-31 | 2012-05-31 | Indukcja arteriogenezy donorem NO, takim jak nitrogliceryna |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20150164845A1 (pl) |
| EP (3) | EP2668947B1 (pl) |
| JP (1) | JP6280106B2 (pl) |
| CN (2) | CN110251500A (pl) |
| AU (2) | AU2013269631B2 (pl) |
| CA (1) | CA2872465C (pl) |
| DE (1) | DE112013002717T5 (pl) |
| EA (1) | EA032534B1 (pl) |
| ES (2) | ES2617494T3 (pl) |
| HU (2) | HUE033092T2 (pl) |
| PL (2) | PL2668947T3 (pl) |
| TR (1) | TR201908817T4 (pl) |
| WO (1) | WO2013178715A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2668947B1 (en) * | 2012-05-31 | 2016-11-30 | G. Pohl-Boskamp GmbH & Co. KG | Induction of arteriogenesis with a nitric oxide-donor such as nitroglycerin |
| CA3040872A1 (en) * | 2016-12-14 | 2018-06-21 | G. Pohl-Boskamp Gmbh & Co. Kg | Reducing side effects of short acting no donors |
| TWI650326B (zh) * | 2017-10-24 | 2019-02-11 | 國立交通大學 | 醫藥組合物、化合物的用途及合成方法 |
| WO2021073535A1 (zh) * | 2019-10-16 | 2021-04-22 | 上海岸阔医药科技有限公司 | 预防或治疗与vegfr和/或vegf被抑制相关疾病的方法 |
| CN110934865A (zh) * | 2019-12-06 | 2020-03-31 | 牡丹江医学院 | 一种用于预防和治疗血液透析低血压的药物组合物及其用途 |
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| BE632504A (pl) | 1962-05-24 | |||
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| JPS599539B2 (ja) | 1979-11-13 | 1984-03-03 | 日本化薬株式会社 | ニトログリセリン水溶液及びその製造法 |
| CA1163195A (en) | 1980-06-26 | 1984-03-06 | Alec D. Keith | Polymeric diffusion matrix containing a vasodilator |
| US4542013A (en) | 1981-07-08 | 1985-09-17 | Key Pharmaceuticals, Inc. | Trinitroglycerol sustained release vehicles and preparation therefrom |
| DE3246081A1 (de) | 1982-12-13 | 1984-06-14 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Nitroglycerin-spray |
| US4671953A (en) | 1985-05-01 | 1987-06-09 | University Of Utah Research Foundation | Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics |
| EP0341264A4 (en) | 1987-01-23 | 1991-03-20 | The General Hospital Corporation | Atriopeptins, guanylate cyclase activators, and phosphodiesterase inhibitors as treatment for glaucoma, hydrocephalus and cerebral edema (cranial fluid volume dysfunction) |
| JPH0645538B2 (ja) | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
| HU199678B (en) | 1988-07-08 | 1990-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing aerosols containing nitroglicerol |
| DE4007705C1 (pl) | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
| US5370862A (en) | 1990-06-13 | 1994-12-06 | Schwarz Pharma Ag | Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina |
| DE4018919C2 (de) | 1990-06-13 | 1994-08-25 | Sanol Arznei Schwarz Gmbh | Nitroglycerin-Spray |
| DE4026072A1 (de) | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
| DE4038203A1 (de) | 1990-11-30 | 1992-06-04 | Kali Chemie Pharma Gmbh | Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen |
| US5698589A (en) | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
| EP1393723A3 (en) * | 1993-09-17 | 2004-10-20 | The Brigham And Women's Hospital, Inc. | Use of nitric oxide-adducts to prevent thrombosis on artificial and vascular surfaces |
| US5869082A (en) | 1996-04-12 | 1999-02-09 | Flemington Pharmaceutical Corp. | Buccal, non-polar spray for nitroglycerin |
| US20010044584A1 (en) | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
| US20030095925A1 (en) | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
| EP1019039B1 (en) | 1997-10-03 | 2001-12-05 | Warner-Lambert Company | Compressed nitroglycerin tablet and its method of manufacture |
| US6796966B2 (en) | 1997-10-15 | 2004-09-28 | Jeffrey E. Thomas | Apparatus, and kits for preventing of alleviating vasoconstriction or vasospasm in a mammal |
| WO1999038472A2 (en) | 1998-01-28 | 1999-08-05 | Seatrace Pharmaceuticals Inc | Topical vasodilatory gel composition and methods of use and production |
| US5989529A (en) | 1998-11-20 | 1999-11-23 | Schering-Plough Healthcare Products, Inc. | Substantive topical composition |
| IT1303793B1 (it) | 1998-11-27 | 2001-02-23 | Promefarm S R L | "composizione farmaceutica comprendente un composto organico donatoredi ossido nitrico (no)" |
| US6962691B1 (en) | 1999-05-20 | 2005-11-08 | U & I Pharmaceuticals Ltd. | Topical spray compositions |
| RU2174838C2 (ru) | 1999-11-04 | 2001-10-20 | Ивановская государственная медицинская академия | Способ лечения тяжелого бронхообструктивного синдрома у детей раннего возраста |
| AU2727701A (en) | 1999-12-15 | 2001-06-25 | Cellegy Pharmaceuticals, Inc. | Nitroglycerin ointment for treatment of pain associated with anal disease |
| US6443307B1 (en) | 2000-01-25 | 2002-09-03 | Michael D. Burridge | Medication dispenser with an internal ejector |
| WO2001068062A2 (en) | 2000-03-14 | 2001-09-20 | Noven Pharmaceuticals, Inc. | Packaging materials for transdermal drug delivery systems |
| US6538033B2 (en) | 2000-08-29 | 2003-03-25 | Huntington Medical Research Institutes | Nitric oxide donor compounds |
| CN1545421A (zh) | 2001-06-22 | 2004-11-10 | �Ʒ� | 包含低溶解度和/或酸敏感的药物以及中和的酸性聚合物的药物组合物 |
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| US20050095278A1 (en) | 2003-01-14 | 2005-05-05 | Viorel Nicolaescu | Use of nitroglycerin to relieve nocturnal muscle cramps |
| US20040228883A1 (en) | 2003-02-21 | 2004-11-18 | Mitchell Karl | Prepackaged aqueous pharmaceutical formulation for the treatment of cardiac conditions containing at least two different active agents and method of formulation |
| WO2005004989A2 (en) | 2003-07-01 | 2005-01-20 | Todd Maibach | Film comprising therapeutic agents |
| US20070053966A1 (en) | 2003-10-17 | 2007-03-08 | Robert Ang | Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue |
| US7781226B2 (en) | 2004-02-27 | 2010-08-24 | The Board Of Regents Of The University Of Texas System | Particle on membrane assay system |
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| FR2868314B1 (fr) * | 2004-04-05 | 2008-10-24 | Therabel Pharmaceuticals Ltd | Nouvelle utilisation therapeutique de la molsidomine et de ses sels pharmaceutiquement acceptables |
| WO2005107461A2 (en) | 2004-04-07 | 2005-11-17 | The General Hospital Corporation | Modulating lymphatic function |
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| EP2015632B1 (en) | 2006-04-19 | 2015-12-02 | Mist Pharmaceuticals, LLC | Stable hydroalcoholic oral spray formulations and methods |
| CA2678097C (en) | 2007-02-26 | 2023-03-14 | Jon Lundberg | New use of nitrites and nitrates and compositions containing these |
| MX2010006719A (es) * | 2007-12-18 | 2010-09-28 | Athera Biotechnologies Ab | Compuestos y metodos para el tratamiento de enfermedad vascular. |
| CN101229148A (zh) | 2007-12-28 | 2008-07-30 | 天津医科大学 | 硝酸甘油口腔(舌下)崩解片的制剂及其制备方法 |
| DE102008005484A1 (de) * | 2008-01-22 | 2009-07-23 | Schaper, Wolfgang, Dr. | Induktion und Förderung der Arteriogenese |
| EP2098249B1 (en) | 2008-03-05 | 2012-10-24 | Rivopharm SA | Nicorandil carriers with enhanced stability |
| DE202008007318U1 (de) | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
| US20100184870A1 (en) | 2008-03-14 | 2010-07-22 | Rolf Groteluschen | Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate |
| US20100016446A1 (en) | 2008-07-21 | 2010-01-21 | Sylvia Gonda | Stable water-based topical pharmaceutical creams and methods of making and using same |
| EP2378957B1 (en) | 2008-12-23 | 2015-09-30 | Charité - Universitätsmedizin Berlin | Method and device for monitoring arteriogenesis |
| CA2671029A1 (en) | 2009-06-30 | 2010-12-30 | James S. Baldassarre | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| EP2600837A1 (en) * | 2010-08-03 | 2013-06-12 | G. Pohl-Boskamp GmbH & Co. KG | Use of glyceryl trinitrate for treating hematomas |
| CA2827714A1 (en) * | 2011-02-25 | 2012-08-30 | G. Pohl-Boskamp Gmbh & Co. Kg | Packaging of solid pharmaceutical preparations containing the active substance glyceryl trinitrate |
| US9248099B2 (en) * | 2012-05-31 | 2016-02-02 | Desmoid Aktiengesellschaft | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| EP2668948A1 (en) | 2012-05-31 | 2013-12-04 | G. Pohl-Boskamp GmbH & Co. KG | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| EP2668947B1 (en) * | 2012-05-31 | 2016-11-30 | G. Pohl-Boskamp GmbH & Co. KG | Induction of arteriogenesis with a nitric oxide-donor such as nitroglycerin |
| US20140057977A1 (en) | 2012-05-31 | 2014-02-27 | G. Pohl-Boskamp Gmbh & Co. Kg | Induction of Arteriogenesis |
| CA2778679A1 (en) * | 2012-05-31 | 2013-11-30 | G. Pohl-Boskamp Gmbh & Co. Kg | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| JP5996371B2 (ja) | 2012-10-29 | 2016-09-21 | 株式会社東芝 | 電子機器 |
| EP2805730A1 (en) | 2013-05-21 | 2014-11-26 | Bergen Teknologioverforing AS | Nitric oxide donor for the treatment of chronic fatigue syndrome |
| EP2878310B1 (en) | 2013-11-29 | 2017-01-11 | G. Pohl-Boskamp GmbH & Co. KG | Sprayable aqueous composition comprising glyceryl trinitrate |
| CA3040872A1 (en) | 2016-12-14 | 2018-06-21 | G. Pohl-Boskamp Gmbh & Co. Kg | Reducing side effects of short acting no donors |
-
2012
- 2012-05-31 EP EP12004187.6A patent/EP2668947B1/en not_active Not-in-force
- 2012-05-31 PL PL12004187T patent/PL2668947T3/pl unknown
- 2012-05-31 ES ES12004187.6T patent/ES2617494T3/es active Active
- 2012-05-31 HU HUE12004187A patent/HUE033092T2/hu unknown
-
2013
- 2013-05-29 EA EA201492251A patent/EA032534B1/ru not_active IP Right Cessation
- 2013-05-29 WO PCT/EP2013/061131 patent/WO2013178715A1/en not_active Ceased
- 2013-05-29 US US14/403,713 patent/US20150164845A1/en not_active Abandoned
- 2013-05-29 HU HUE13726197A patent/HUE044056T2/hu unknown
- 2013-05-29 DE DE112013002717.8T patent/DE112013002717T5/de not_active Withdrawn
- 2013-05-29 ES ES13726197T patent/ES2731664T3/es active Active
- 2013-05-29 PL PL13726197T patent/PL2877170T3/pl unknown
- 2013-05-29 JP JP2015514497A patent/JP6280106B2/ja not_active Expired - Fee Related
- 2013-05-29 CN CN201910506944.9A patent/CN110251500A/zh active Pending
- 2013-05-29 EP EP18179582.4A patent/EP3412285A3/en not_active Withdrawn
- 2013-05-29 CA CA2872465A patent/CA2872465C/en active Active
- 2013-05-29 AU AU2013269631A patent/AU2013269631B2/en not_active Ceased
- 2013-05-29 TR TR2019/08817T patent/TR201908817T4/tr unknown
- 2013-05-29 EP EP13726197.0A patent/EP2877170B1/en active Active
- 2013-05-29 CN CN201380028543.8A patent/CN104519881A/zh active Pending
-
2017
- 2017-03-06 US US15/450,656 patent/US11166931B2/en not_active Expired - Fee Related
-
2018
- 2018-02-05 AU AU2018200831A patent/AU2018200831A1/en not_active Abandoned
-
2021
- 2021-09-22 US US17/448,508 patent/US20220096417A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013178715A1 (en) | 2013-12-05 |
| EP3412285A3 (en) | 2019-02-20 |
| PL2668947T3 (pl) | 2017-06-30 |
| US20170172966A1 (en) | 2017-06-22 |
| EP2668947B1 (en) | 2016-11-30 |
| DE112013002717T5 (de) | 2015-02-26 |
| JP6280106B2 (ja) | 2018-02-14 |
| EP2668947A1 (en) | 2013-12-04 |
| HUE044056T2 (hu) | 2019-09-30 |
| AU2013269631B2 (en) | 2018-03-01 |
| US20150164845A1 (en) | 2015-06-18 |
| AU2018200831A1 (en) | 2018-02-22 |
| HUE033092T2 (hu) | 2017-11-28 |
| CA2872465C (en) | 2021-02-16 |
| CN104519881A (zh) | 2015-04-15 |
| CN110251500A (zh) | 2019-09-20 |
| EP2877170A1 (en) | 2015-06-03 |
| EA201492251A1 (ru) | 2015-05-29 |
| AU2013269631A1 (en) | 2014-11-13 |
| JP2015518030A (ja) | 2015-06-25 |
| EP3412285A2 (en) | 2018-12-12 |
| ES2617494T3 (es) | 2017-06-19 |
| EA032534B1 (ru) | 2019-06-28 |
| US11166931B2 (en) | 2021-11-09 |
| EP2877170B1 (en) | 2019-04-10 |
| US20220096417A1 (en) | 2022-03-31 |
| CA2872465A1 (en) | 2013-12-05 |
| ES2731664T3 (es) | 2019-11-18 |
| TR201908817T4 (tr) | 2019-07-22 |
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