PL2982761T3 - Zastosowanie HE4 i innych markerów biochemicznych do oceny raka endometrium i raka macicy - Google Patents

Zastosowanie HE4 i innych markerów biochemicznych do oceny raka endometrium i raka macicy

Info

Publication number
PL2982761T3
PL2982761T3 PL15175154T PL15175154T PL2982761T3 PL 2982761 T3 PL2982761 T3 PL 2982761T3 PL 15175154 T PL15175154 T PL 15175154T PL 15175154 T PL15175154 T PL 15175154T PL 2982761 T3 PL2982761 T3 PL 2982761T3
Authority
PL
Poland
Prior art keywords
cancer
biochemical markers
evaluate
uterine
endometrial cancer
Prior art date
Application number
PL15175154T
Other languages
English (en)
Inventor
Richard Moore
Elizabeth Somers
Jeffrey W. Allard
Original Assignee
Fujirebio America, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio America, Inc. filed Critical Fujirebio America, Inc.
Publication of PL2982761T3 publication Critical patent/PL2982761T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5755—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the uterine cervix, uterine corpus or endometrium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
PL15175154T 2006-01-04 2007-01-04 Zastosowanie HE4 i innych markerów biochemicznych do oceny raka endometrium i raka macicy PL2982761T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75613106P 2006-01-04 2006-01-04
EP15175154.2A EP2982761B1 (en) 2006-01-04 2007-01-04 Use of he4 and other biochemical markers for assessment of endometrial and uterine cancers
EP07717842A EP1969136A4 (en) 2006-01-04 2007-01-04 USE OF HE4 AND OTHER BIOCHEMICAL MARKERS FOR THE ASSESSMENT OF ENDOMETRIC AND BEARNUT CANCER

Publications (1)

Publication Number Publication Date
PL2982761T3 true PL2982761T3 (pl) 2018-03-30

Family

ID=38256906

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15175154T PL2982761T3 (pl) 2006-01-04 2007-01-04 Zastosowanie HE4 i innych markerów biochemicznych do oceny raka endometrium i raka macicy

Country Status (7)

Country Link
US (8) US20070286865A1 (pl)
EP (6) EP1846768A4 (pl)
JP (3) JP5164855B2 (pl)
CN (3) CN101473041B (pl)
ES (2) ES2748397T3 (pl)
PL (1) PL2982761T3 (pl)
WO (2) WO2007081767A2 (pl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000076014A2 (en) * 1999-06-09 2000-12-14 Moltech Corporation Methods of preparing electrochemical cells
US7270960B2 (en) 2001-08-29 2007-09-18 Pacific Northwest Research Institute Diagnosis of ovarian carcinomas
WO2006119155A2 (en) * 2005-05-02 2006-11-09 The Brigham And Women's Hospital, Inc. Diagnostic serum antibody profiling
US20070286865A1 (en) * 2006-01-04 2007-12-13 Richard Moore Use of HE4 and other biochemical markers for assessment of ovarian cancers
JP2009524438A (ja) * 2006-01-27 2009-07-02 トライパス イメージング インコーポレイテッド 卵巣癌を有する可能性の高い患者を同定するための方法およびそのための組成物
EP2087152B1 (en) 2006-10-27 2015-03-11 Walfish, Paul Endometrial biomarkers
EP2121761A1 (en) * 2007-03-09 2009-11-25 Tripath Imaging, Inc. He4 monoclonal antibodies and methods for their use
US8455189B2 (en) * 2007-03-29 2013-06-04 Jeffrey W. Allard Use of HE4 for assessment of breast cancers
CN101377502A (zh) * 2007-08-31 2009-03-04 北京科美东雅生物技术有限公司 肿瘤相关抗原72-4化学发光免疫分析测定试剂盒及其制备方法
WO2009099561A2 (en) * 2008-01-31 2009-08-13 The Brigham And Womens' Hospital, Inc. Urinary ca125 peptides as biomarkers of ovarian cancer
US8476026B2 (en) * 2008-04-01 2013-07-02 The Brigham And Women's Hospital, Inc. Biomarkers of ovarian cancer
MX2013002268A (es) * 2010-08-26 2014-02-03 Univ Washington Ct Commerciali Metodos para detectar anticuerpos anti-he4 y metodos de diagnosis y/o de prognosis de condiciones asociadas con celulas que expresan he4.
ES2834617T3 (es) 2011-02-17 2021-06-18 Fujirebio Diagnostics Inc Composiciones y métodos de uso para la determinación de HE4a
CN103582815A (zh) * 2011-02-24 2014-02-12 佛米利昂公司 用于卵巢癌的生物标志物组、诊断方法和测试试剂盒
CN102735840B (zh) * 2011-04-13 2014-06-04 中国医学科学院肿瘤研究所 用于诊断或筛查卵巢癌的试剂
WO2012170513A2 (en) * 2011-06-06 2012-12-13 Women & Infants' Hospital Of Rhode Island He4 based therapy for malignant disease
DE102012205164B4 (de) 2012-03-29 2021-09-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Projektionsdisplay und Verfahren zur Projektion virtueller Bilder
CN103575902B (zh) * 2012-08-03 2015-07-29 河南生生医疗器械有限公司 一种时间分辨荧光法四项综合检测卵巢癌试剂盒及其应用
CN102890083B (zh) * 2012-09-28 2016-08-10 辽宁科骏生物有限公司 化学发光底物溶液和含其的试剂盒及应用其的检测方法
CN104655858B (zh) * 2015-03-12 2016-02-10 德迈基生物技术(北京)有限公司 定量检测人附睾分泌蛋白-4的荧光免疫层析试剂盒及其制备方法
WO2016154629A1 (en) 2015-03-26 2016-09-29 Woman & Infants' Hospital Of Rhode Island Therapy for malignant disease
RU2585959C1 (ru) * 2015-06-22 2016-06-10 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ дифференциальной диагностики асцитно-инфильтративной формы рака яичников и абдоминального туберкулёза
US10267802B2 (en) 2015-09-23 2019-04-23 The Board Of Trustees Of The Leland Stanford Junior University Methods of prognosis and diagnosis of ovarian cancer
RU2624508C1 (ru) * 2016-06-29 2017-07-04 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ прогнозирования длительности ремиссии у больных раком вульвы
JP2019524706A (ja) * 2016-07-08 2019-09-05 ジェネンテック, インコーポレイテッド Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用
WO2021216670A1 (en) 2020-04-21 2021-10-28 University Of Rochester Inhibitors of human epididymus protein 4
CN111781364B (zh) * 2020-08-25 2023-07-21 北京信诺卫康科技有限公司 Wnt7a和HE4联合用作早期卵巢癌生物标志物以及试剂盒
JP2024505333A (ja) 2020-12-21 2024-02-06 フリーノム ホールディングス,インク. 結腸細胞増殖障害の早期検出のためのマーカー
US20240385195A1 (en) * 2022-04-08 2024-11-21 Ajou University Industry-Academic Cooperation Foundation Peptide for detecting ca125 and use thereof
US20240353411A1 (en) * 2022-04-08 2024-10-24 Ajou University Industry-Academic Cooperation Foundation He4 detecting peptide and use thereof
CN120254284B (zh) * 2025-06-03 2025-08-22 杭州广科安德生物科技有限公司 一种用于预测子宫内膜癌复发或转移风险的生物标志物及其应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
CA1289880C (en) * 1985-12-06 1991-10-01 Jeffrey L. Winkelhake Anti-human ovarian cancer immunotoxins and methods of use thereof
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5091513A (en) * 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
JPH02500329A (ja) 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US6998106B1 (en) * 1998-12-01 2006-02-14 Duke University Radioconjugation of internalizing antibodies
ATE328280T1 (de) 1999-02-26 2006-06-15 Pacific Northwest Res Inst Verfahren und zusammensetzungen zur karzinomdiagnose
US6770445B1 (en) * 1999-02-26 2004-08-03 Pacific Northwest Research Institute Methods and compositions for diagnosing carcinomas
WO2002046765A2 (en) * 2000-11-08 2002-06-13 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of ovarian cancer
US7270960B2 (en) * 2001-08-29 2007-09-18 Pacific Northwest Research Institute Diagnosis of ovarian carcinomas
US20030226155A1 (en) * 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
DE60332639D1 (de) * 2002-08-06 2010-07-01 Univ Johns Hopkins Verwendung von biomarkern zum nachweis von eierstockkrebs
EP1546723A4 (en) * 2002-08-16 2007-03-07 Decision Biomarkers Inc READING FLUORESCENCE CARIES
AU2003290773A1 (en) * 2003-02-05 2004-09-06 Ciphergen Biosystems, Inc. Non-invasive assessment of intra-amniotic environment
US7619068B2 (en) * 2003-05-09 2009-11-17 Diadexus, Inc. Ovr110 antibody compositions and methods of use
CN1266475C (zh) * 2003-06-05 2006-07-26 马旭 一种用于诊断早期卵巢癌的四粘蛋白酶联免疫检测试剂盒
EP1723428A2 (en) * 2004-02-19 2006-11-22 Yale University Corporation Identification of cancer protein biomarkers using proteomic techniques
WO2005098446A2 (en) * 2004-03-31 2005-10-20 The Johns Hopkins University Biomarkers for ovarian cancer
ATE408828T1 (de) * 2005-02-16 2008-10-15 Dana Farber Cancer Inst Inc Verfahren zur erkennung eines ovarialkarzinoms
CN101243319B (zh) * 2005-06-22 2016-01-06 约翰·霍普金斯大学 卵巢癌的生物标记:ctap3-相关蛋白质
US8465929B2 (en) * 2005-06-24 2013-06-18 Vermillion, Inc. Biomarkers for ovarian cancer
US20070286865A1 (en) * 2006-01-04 2007-12-13 Richard Moore Use of HE4 and other biochemical markers for assessment of ovarian cancers

Also Published As

Publication number Publication date
US20070286865A1 (en) 2007-12-13
HK1219514A1 (en) 2017-04-07
CN101473041B (zh) 2017-11-14
EP2982761B1 (en) 2017-10-04
WO2007081767A2 (en) 2007-07-19
ES2650244T3 (es) 2018-01-17
US20180180620A1 (en) 2018-06-28
EP2423321A3 (en) 2012-03-14
WO2007081768A3 (en) 2008-04-24
CN101460630B (zh) 2016-08-10
JP2009522578A (ja) 2009-06-11
US20080020473A1 (en) 2008-01-24
EP2982761A1 (en) 2016-02-10
JP2009521953A (ja) 2009-06-11
CN106124765A (zh) 2016-11-16
US20240230652A9 (en) 2024-07-11
WO2007081768A2 (en) 2007-07-19
EP1969136A2 (en) 2008-09-17
ES2748397T3 (es) 2020-03-16
WO2007081767A3 (en) 2008-04-24
JP5164855B2 (ja) 2013-03-21
EP3026119A1 (en) 2016-06-01
US20240133889A1 (en) 2024-04-25
EP1846768A2 (en) 2007-10-24
CN101460630A (zh) 2009-06-17
JP2013050457A (ja) 2013-03-14
US20180156805A1 (en) 2018-06-07
EP2420576A3 (en) 2012-03-14
JP5221381B2 (ja) 2013-06-26
EP1846768A4 (en) 2009-04-08
EP2423321A2 (en) 2012-02-29
EP3026119B1 (en) 2019-09-18
EP1969136A4 (en) 2009-04-15
JP5711196B2 (ja) 2015-04-30
CN101473041A (zh) 2009-07-01
US20240288434A1 (en) 2024-08-29
US20200292549A1 (en) 2020-09-17
EP2420576A2 (en) 2012-02-22
US20200182878A1 (en) 2020-06-11

Similar Documents

Publication Publication Date Title
EP2423321A3 (en) Use of HE4 and other biochemical markers for assessment of endometrial and uterine cancers
MX2008006581A (es) Edulcorante de alta potencia para hidratacion y composicion de hidratacion edulcorada
BRPI0807966A2 (pt) Aquisição, isolação e criopreservação de células endometriais/menstruais
DE502006003472D1 (de) Markernavigationsvorrichtung insbesondere für medizinische Zwecke
IL240524A0 (en) Activin-actrii antagonists and uses for increasing red blood cell levels
ZA200808278B (en) Use of rylenes as markers for liquids
EP2109834A4 (en) VISUALIZATION AND NAVIGATION OF SEARCH RESULTS
ES2439244T8 (es) Inhibidores de serina proteasa tipo tripsina, su preparación y uso
PL2371385T3 (pl) Zastosowanie kompozycji immunogennej do zmniejszania objawów klinicznych u świń
EP2047864A4 (en) USE OF RPN2 GENE EXPRESSION INHIBITOR
BRPI1007448A2 (pt) catalisador com distribuição bimodal de tamanho de poros e uso do mesmo
ATE502172T1 (de) Vorrichtung für den einsatz beim bau von gebäuden
BRPI0813627A2 (pt) Peptídio antimicrobiano, composições e métodos de uso
EP1730507A4 (en) QUANTITATIVE TRANSIENT ANALYSIS OF LOCALIZED CORROSION
CR9218A (es) Cemento impermeable y composicion sinergica empleada para la obtencion de alta impermeabilidad
BRPI0714209A2 (pt) Induzidor de morte celular
BRPI0713736A2 (pt) Derivados de tetralina e indano e emprego destes
PT1978981E (pt) Composições para uso vaginal
BRPI0914064A2 (pt) composição veterinária, uso de composição veterinária e kit veterinário
CR9853A (es) Compuestos de exemestano (s)-6-metiloxaalquilo y metodos relacionados con su utilizacion
EP1937816A4 (en) MARKERS FOR CANCER DIAGNOSIS AND USE THEREOF
EP1907857A4 (en) BIOMARKER FOR BREAST CANCER
AU312767S (en) Instrument panel for working vehicles
EP2126577A4 (en) Use of he4 for assessment of breast cancers
DE602006019622D1 (de) Zubereitung zur topischen anwendung enthaltend tamsulosin