PL312078A1 - Novel derivatives of 2-amino 4-phenylthiazole and method of obtaining them as well as pharmaceutical agents containing such derivatives - Google Patents

Novel derivatives of 2-amino 4-phenylthiazole and method of obtaining them as well as pharmaceutical agents containing such derivatives

Info

Publication number
PL312078A1
PL312078A1 PL95312078A PL31207895A PL312078A1 PL 312078 A1 PL312078 A1 PL 312078A1 PL 95312078 A PL95312078 A PL 95312078A PL 31207895 A PL31207895 A PL 31207895A PL 312078 A1 PL312078 A1 PL 312078A1
Authority
PL
Poland
Prior art keywords
derivatives
phenylthiazole
amino
obtaining
well
Prior art date
Application number
PL95312078A
Other languages
English (en)
Inventor
Alain Badorc
Marie-Francoise Bordes
Cointet Paul De
Jean-Marc Herbert
Jean-Pierre Maffrand
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PL312078A1 publication Critical patent/PL312078A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PL95312078A 1994-12-28 1995-12-28 Novel derivatives of 2-amino 4-phenylthiazole and method of obtaining them as well as pharmaceutical agents containing such derivatives PL312078A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9415805A FR2728901B1 (fr) 1994-12-28 1994-12-28 Derives de phenyl-4-thiazoles substitues, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
PL312078A1 true PL312078A1 (en) 1996-07-08

Family

ID=9470360

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95312078A PL312078A1 (en) 1994-12-28 1995-12-28 Novel derivatives of 2-amino 4-phenylthiazole and method of obtaining them as well as pharmaceutical agents containing such derivatives

Country Status (28)

Country Link
US (1) US5607952A (de)
EP (1) EP0719775B1 (de)
JP (1) JP3027110B2 (de)
KR (1) KR960022515A (de)
CN (1) CN1048726C (de)
AR (1) AR002017A1 (de)
AT (1) ATE194616T1 (de)
AU (1) AU703490B2 (de)
BR (1) BR1100524A (de)
CA (1) CA2166165A1 (de)
CZ (1) CZ346595A3 (de)
DE (1) DE69517936T2 (de)
DK (1) DK0719775T3 (de)
ES (1) ES2148458T3 (de)
FI (1) FI956278A7 (de)
FR (1) FR2728901B1 (de)
GR (1) GR3034582T3 (de)
HU (1) HUT75096A (de)
IL (1) IL116560A (de)
NO (1) NO306114B1 (de)
NZ (1) NZ280720A (de)
PL (1) PL312078A1 (de)
PT (1) PT719775E (de)
RU (1) RU2124515C1 (de)
SI (1) SI0719775T1 (de)
SK (1) SK281247B6 (de)
TW (1) TW418207B (de)
ZA (1) ZA9511029B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840733A (en) * 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
FR2764511B1 (fr) * 1997-06-13 2000-09-08 Sanofi Sa Compositions pour le traitement et la prevention de la thrombose arterielle et utilisation d'un inhibiteur du facteur xa seul et/ou en combinaison avec un antiagregant plaquettaire
AU1735200A (en) 1998-11-18 2000-06-05 Du Pont Pharmaceuticals Company Novel isoxazoline fibrinogen receptor antagonists
US6319937B1 (en) 1998-11-18 2001-11-20 Dupont Pharmaceuticals Company Isoxazoline fibrinogen receptor antagonists
FR2797400A1 (fr) * 1999-08-11 2001-02-16 Sanofi Synthelabo Associations a activite anti-thrombotique constituees de l'hydrogenosulfate de clopidogrel et d'un antagoniste des recepteurs gpiib/iiia et les compositions pharmaceutiques les contenant
TWI284639B (en) * 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US20060198836A1 (en) * 2003-07-17 2006-09-07 Smithkline Beecham Corporation Method of treating hit patients with argatroban
US7601746B2 (en) * 2003-08-12 2009-10-13 Shionogi & Co., Ltd. Compounds exhibiting thrombopoietin receptor agonism
CA2533464A1 (en) * 2003-08-12 2005-02-17 F. Hoffmann-La Roche Ag Thiazole derivatives as npy antagonists
CA2566081A1 (en) * 2004-05-13 2005-12-01 Boehringer Ingelheim International Gmbh Use of dipyridamole for treatment of resistance to platelet inhibitors
JP2007538257A (ja) * 2004-05-17 2007-12-27 メドトロニック・インコーポレーテッド ポイント・オブ・ヘパリン測定システム
US7423053B2 (en) * 2004-07-15 2008-09-09 Hoffmann-La Roche Inc. 4-Aminothiazole derivatives
RU2391340C2 (ru) * 2004-08-11 2010-06-10 Киорин Фармасьютикал Ко., Лтд. Новое циклическое производное аминобензойной кислоты
WO2007003960A1 (en) * 2005-06-30 2007-01-11 Prosidion Limited Gpcr agonists
RU2373929C1 (ru) * 2008-11-11 2009-11-27 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) Корректор системы гемостаза, проявляющий ингибирующее действие на адгезивно-агрегационную функцию тромбоцитов для профилактики патологического тромбообразования

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB542363A (en) * 1940-07-03 1942-01-06 Joseph Arthur Musgrave Woodcoc Improvements in or relating to the manufacture of graphite electrodes
DK157135C (da) * 1982-04-07 1990-04-02 Pfizer Analogifremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DE3839758A1 (de) * 1988-10-24 1990-04-26 Bayer Ag Substituierte 2-aminothiazole
US5231091A (en) * 1988-12-19 1993-07-27 American Cyanamid Company Bis-arylphosphate ester antagonists of platelet activating factor
FR2656610B1 (fr) * 1989-12-29 1992-05-07 Sanofi Sa Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique.
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
US5405848A (en) * 1993-12-22 1995-04-11 Ortho Pharmaceutical Corporation Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors

Also Published As

Publication number Publication date
JPH08231542A (ja) 1996-09-10
NO306114B1 (no) 1999-09-20
HU9503801D0 (en) 1996-02-28
SI0719775T1 (en) 2000-12-31
PT719775E (pt) 2000-12-29
AR002017A1 (es) 1998-01-07
IL116560A (en) 2001-03-19
ES2148458T3 (es) 2000-10-16
CZ346595A3 (en) 1996-08-14
JP3027110B2 (ja) 2000-03-27
NZ280720A (en) 1997-10-24
AU4070995A (en) 1996-07-04
NO955320D0 (no) 1995-12-27
NO955320L (no) 1996-07-01
TW418207B (en) 2001-01-11
US5607952A (en) 1997-03-04
RU2124515C1 (ru) 1999-01-10
FI956278A0 (fi) 1995-12-27
SK163395A3 (en) 1996-09-04
DE69517936T2 (de) 2001-04-19
SK281247B6 (sk) 2001-01-18
FR2728901A1 (fr) 1996-07-05
EP0719775A1 (de) 1996-07-03
GR3034582T3 (en) 2001-01-31
BR1100524A (pt) 2000-03-14
CA2166165A1 (en) 1996-06-29
CN1133289A (zh) 1996-10-16
FI956278L (fi) 1996-06-29
ATE194616T1 (de) 2000-07-15
DK0719775T3 (da) 2000-10-23
EP0719775B1 (de) 2000-07-12
DE69517936D1 (de) 2000-08-17
AU703490B2 (en) 1999-03-25
FI956278A7 (fi) 1996-06-29
IL116560A0 (en) 1996-03-31
KR960022515A (ko) 1996-07-18
FR2728901B1 (fr) 1997-03-28
CN1048726C (zh) 2000-01-26
ZA9511029B (en) 1997-06-30
HUT75096A (en) 1997-04-28

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