PL313386A1 - Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them - Google Patents

Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them

Info

Publication number
PL313386A1
PL313386A1 PL95313386A PL31338695A PL313386A1 PL 313386 A1 PL313386 A1 PL 313386A1 PL 95313386 A PL95313386 A PL 95313386A PL 31338695 A PL31338695 A PL 31338695A PL 313386 A1 PL313386 A1 PL 313386A1
Authority
PL
Poland
Prior art keywords
pearls
novel
drug release
preparation containing
controllable drug
Prior art date
Application number
PL95313386A
Other languages
English (en)
Inventor
Lars Stubberud
Hans Arwidsson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of PL313386A1 publication Critical patent/PL313386A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL95313386A 1994-07-08 1995-06-07 Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them PL313386A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402422A SE9402422D0 (sv) 1994-07-08 1994-07-08 New beads for controlled release and a pharmaceutical preparation containing the same
PCT/SE1995/000676 WO1996001621A1 (en) 1994-07-08 1995-06-07 New beads for controlled release and a pharmaceutical preparation containing the same

Publications (1)

Publication Number Publication Date
PL313386A1 true PL313386A1 (en) 1996-06-24

Family

ID=20394677

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95313386A PL313386A1 (en) 1994-07-08 1995-06-07 Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them

Country Status (23)

Country Link
US (1) US5783215A (cs)
EP (1) EP0723434A1 (cs)
JP (1) JPH09502738A (cs)
CN (1) CN1134108A (cs)
AU (1) AU700949B2 (cs)
BR (1) BR9506026A (cs)
CA (1) CA2170526A1 (cs)
CZ (1) CZ73196A3 (cs)
EE (1) EE03280B1 (cs)
FI (1) FI961056L (cs)
HU (1) HUT75772A (cs)
IL (1) IL114448A (cs)
MX (1) MX9600858A (cs)
NO (1) NO960837D0 (cs)
NZ (1) NZ289947A (cs)
PL (1) PL313386A1 (cs)
RU (1) RU2141822C1 (cs)
SE (1) SE9402422D0 (cs)
SK (1) SK30396A3 (cs)
TR (1) TR199500822A2 (cs)
TW (1) TW460300B (cs)
WO (1) WO1996001621A1 (cs)
ZA (1) ZA955545B (cs)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
FR2758461A1 (fr) * 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration
SE9702533D0 (sv) 1997-07-01 1997-07-01 Astra Ab New oral formulation
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
CO5070568A1 (es) 1998-05-22 2001-08-28 Eurand Internatrional Spa Proceso de aplicacion de capas y aparato para efectuarlo
SE9803871D0 (sv) * 1998-11-11 1998-11-11 Pharmacia & Upjohn Ab Therapeutic method and formulation
DE19842753A1 (de) * 1998-09-18 2000-03-23 Bayer Ag Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
FR2795961B1 (fr) 1999-07-09 2004-05-28 Ethypharm Lab Prod Ethiques Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation
US7863331B2 (en) 1999-07-09 2011-01-04 Ethypharm Pharmaceutical composition containing fenofibrate and method for the preparation thereof
MXPA02004574A (es) 1999-11-11 2004-09-10 Pharmacia Ab Formulacion farmaceutica que contiene tolterodina y su uso.
CA2456034A1 (en) * 2001-08-03 2003-02-20 Takeda Chemical Industries, Ltd. Sustained-release medicines
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US20030133982A1 (en) * 2001-12-20 2003-07-17 Heimlich John M. Zero-order sustained release dosage forms and method of making same
US20030181488A1 (en) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
CO5400144A1 (es) 2002-03-11 2004-05-31 Novartis Ag Compuestos organicos
US7022342B2 (en) * 2002-03-28 2006-04-04 Andrx Corporation, Inc. Controlled release oral dosage form of beta-adrenergic blocking agents
AU2003236947A1 (en) * 2002-06-07 2003-12-22 Ranbaxy Laboratories Limited Modified release, multiple unit drug delivery systems
US7803402B2 (en) * 2002-07-06 2010-09-28 Sanjeev Khandelwal Pharmaceutical preparations
FR2842736B1 (fr) * 2002-07-26 2005-07-22 Flamel Tech Sa Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s)
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
JP2006516574A (ja) 2003-02-05 2006-07-06 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール安定化方法
EP1635795A1 (en) * 2003-05-30 2006-03-22 Ranbaxy Laboratories, Ltd. Controlled release pharmaceutical compositions of tolterodine and processes for their preparation
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
TWI372066B (en) * 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
US8734850B2 (en) * 2003-11-25 2014-05-27 Flamel Technologies Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
RU2261095C1 (ru) * 2004-01-09 2005-09-27 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственная форма, обладающая нестероидным противовоспалительным действием, и способ ее изготовления
US20070224269A1 (en) * 2004-06-10 2007-09-27 Rubino Orapin P Controlled Release Pharmaceutical Formulation
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
DK1915137T3 (da) 2005-08-10 2013-11-04 Add Advanced Drug Delivery Technologies Ltd Oralt præparat med kontrolleret frisætning
US20070141151A1 (en) * 2005-12-20 2007-06-21 Silver David I Lansoprazole orally disintegrating tablets
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
SI1993559T1 (sl) 2006-02-03 2017-01-31 Opko Renal, Llc Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
RU2008136766A (ru) * 2006-02-24 2010-03-27 Тева Фармасьютикл Индастриес Лтд. (Il) Таблетки метопролола сукцината пролонгированного действия и способы их приготовления
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US20090068263A1 (en) * 2006-04-20 2009-03-12 Themis Laboratories Private Limited Multiple unit compositions
US20070248670A1 (en) * 2006-04-21 2007-10-25 Van Den Heuvel Dennie J M Tolterodine beads
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
PT3357496T (pt) 2006-06-21 2020-05-12 Opko Ireland Global Holdings Ltd Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
WO2008014175A2 (en) * 2006-07-28 2008-01-31 Dr. Reddy's Laboratories Ltd. Granular pharmaceutical compositions
CN101668532B (zh) 2007-04-25 2014-08-20 赛特克罗公司 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的组合物及其相应的制药用途
PL3225243T3 (pl) 2007-04-25 2025-12-22 Opko Renal, Llc Sposób bezpiecznego i skutecznego leczenia i zapobiegania wtórnej nadczynności przytarczyc w przewlekłej chorobie nerek
KR20190141269A (ko) 2007-04-25 2019-12-23 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
EP2173329A1 (en) * 2007-07-03 2010-04-14 Synthon B.V. Tolterodine bead
CA2629099A1 (en) * 2008-04-01 2009-10-01 Pharmascience Inc. Novel oral controlled release pharmaceutical formulations
CN102046812A (zh) 2008-04-02 2011-05-04 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
WO2010023170A1 (en) * 2008-08-29 2010-03-04 Glaxo Group Limited Dosage form comprising 1-isopropyl-4-{[4-(tetrahydro-2H-pyran- 4-yloxy)phenyl]carbonyl}hexahydro-1H-1,4-diazepine or a salt thereof
US9078830B2 (en) 2009-07-31 2015-07-14 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
US20140112995A1 (en) * 2009-07-31 2014-04-24 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
WO2011095388A1 (en) 2010-02-04 2011-08-11 Synthon Bv Tolterodine bead
CA2797537C (en) 2010-03-29 2021-11-23 Cytochroma Inc. Use of 25-hydroxyvitamin d compound for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
AU2014246617A1 (en) 2013-12-23 2015-07-09 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
GB201417828D0 (en) 2014-10-08 2014-11-19 Cereno Scient Ab New methods and compositions
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
RU2744270C2 (ru) * 2015-12-28 2021-03-04 ЭсЭсПи КО., ЛТД., ДЖАПАН Прессованный фармацевтический препарат
IL243707A0 (en) 2016-01-20 2016-05-01 Galmed Res And Dev Ltd Treatment to regulate the microbiota in the intestine
EP4596045A3 (en) 2016-03-28 2025-10-15 EirGen Pharma Ltd. Methods of vitamin d treatment
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN108272766B (zh) * 2018-03-21 2020-07-07 江苏四环生物制药有限公司 一种甲钴胺分散迟释片及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985003436A1 (en) * 1984-02-10 1985-08-15 A/S Alfred Benzon Diffusion coated multiple-units dosage form
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
FR2610327B1 (fr) * 1987-01-30 1989-08-25 Charbonnages Ste Chimique Interpolymere composite a plusieurs couches, son procede de preparation, son application au renforcement de matrices thermoplastiques rigides et compositions renforcees correspondantes
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production
US5084287A (en) * 1990-03-15 1992-01-28 Warner-Lambert Company Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
EP0447168A3 (en) * 1990-03-16 1993-01-07 Yamanouchi Pharmaceutical Co. Ltd. Long acting granular pharmaceutical composition
EP0452862B1 (en) * 1990-04-18 1995-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Spherical seed cores, spherical granules and process for production thereof

Also Published As

Publication number Publication date
EE03280B1 (et) 2000-08-15
CN1134108A (zh) 1996-10-23
SE9402422D0 (sv) 1994-07-08
WO1996001621A1 (en) 1996-01-25
JPH09502738A (ja) 1997-03-18
MX9600858A (es) 1997-06-28
TR199500822A2 (tr) 1996-06-21
FI961056A7 (fi) 1996-05-06
AU700949B2 (en) 1999-01-14
IL114448A0 (en) 1995-11-27
NO960837L (no) 1996-02-29
SK30396A3 (en) 1997-09-10
BR9506026A (pt) 1997-10-14
RU2141822C1 (ru) 1999-11-27
CA2170526A1 (en) 1996-01-25
EP0723434A1 (en) 1996-07-31
HU9600575D0 (en) 1996-07-29
US5783215A (en) 1998-07-21
HUT75772A (en) 1997-05-28
FI961056A0 (fi) 1996-03-07
ZA955545B (en) 1996-01-08
FI961056L (fi) 1996-05-06
TW460300B (en) 2001-10-21
CZ73196A3 (en) 1996-08-14
IL114448A (en) 1999-09-22
NO960837D0 (no) 1996-02-29
NZ289947A (en) 1998-07-28
AU2993695A (en) 1996-02-09

Similar Documents

Publication Publication Date Title
PL313386A1 (en) Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them
AU4227793A (en) Drug infuser
IL118825A0 (en) 6-dimethylaminomethyl -1- phenyl-cyclohexane compounds their preparation and use
IL119864A0 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-OL compounds their preparation and use
EP0425978A3 (en) Nitroguanidine compounds and insecticides
IL100364A0 (en) Benzodiazepinones,their preparation and pharmaceutical compositions containing them
IL90515A0 (en) Benzazepine and bentothiazepine derivatives and processes for the preparation thereof
IL124768A0 (en) Novel pyridine compounds processes for their preparation and their use as pharmaceutical agents
GB9408053D0 (en) Pharmaceutical preparation
GB8919726D0 (en) Ws7338 substances and preparation thereof
GB2272837B (en) Extemporaneous cosmetic or pharmaceutical preparation
IL113415A0 (en) Dihydrodibenzoquinolinediones their preparation and use and pharmaceutical compositions containing them
GB8920304D0 (en) Fr901375 substance and preparation thereof
HUP0004661A3 (en) Polyhydroxybutylpyrazines, their preparation and medicines containing them
EP0721784A4 (en) SLOW RELEASE DRUG PREPARATION
CZ87895A3 (en) Pharmaceutical preparation
EP0488009A3 (en) Piperidinoalkyl-benzoxazine-and-thiazine-compounds, processes for their preparation and drugs containing them
IL104525A0 (en) 4-cinnolinyl-and 4-naphthyridinyl-dihydropyridines,their preparation and pharmaceutical compositions containing them
IL104424A0 (en) Pyrrolylbenzodiazepinones,their preparation and pharmaceutical compositions containing them
ZA911956B (en) 9-chlor-prostaglandin-beta-cyclodextrin-clathrates and their use as medicinal substances
HUP9901126A3 (en) Pharmaceutical composition for external use containing nimesulide and process for the preparation thereof
ZA934523B (en) Medicinal preparation
PL310821A1 (en) Aluminium containing pharmaceutical preparation of controllable active substance release
IL106623A0 (en) Isobutyl-substituted methanesulphonyl-quinolymethoxyphenyl-cycloalkylacetamides,their preparation and pharmaceutical compositions containing them
PH27335A (en) 5-Nitro-tetrahydropyrimidines processes for their preparation and their use as insecticides