PL3279313T3 - Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków - Google Patents

Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków

Info

Publication number
PL3279313T3
PL3279313T3 PL17168855T PL17168855T PL3279313T3 PL 3279313 T3 PL3279313 T3 PL 3279313T3 PL 17168855 T PL17168855 T PL 17168855T PL 17168855 T PL17168855 T PL 17168855T PL 3279313 T3 PL3279313 T3 PL 3279313T3
Authority
PL
Poland
Prior art keywords
bubble production
shigella strains
excessive bubble
excessive
shigella
Prior art date
Application number
PL17168855T
Other languages
English (en)
Inventor
Christiane Gerke
Francesco Berlanda Scorza
Allan Saul
Luana Maggiore
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of PL3279313T3 publication Critical patent/PL3279313T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25Shigella (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0283Shigella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL17168855T 2009-09-28 2010-09-28 Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków PL3279313T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0917002.8A GB0917002D0 (en) 2009-09-28 2009-09-28 Improved shigella blebs
EP17168855.9A EP3279313B1 (en) 2009-09-28 2010-09-28 Hyperblebbing shigella strains
EP10768559.6A EP2483389B1 (en) 2009-09-28 2010-09-28 Hyperblebbing shigella strains
PCT/IB2010/002582 WO2011036564A2 (en) 2009-09-28 2010-09-28 Hyperblebbing shigella strains

Publications (1)

Publication Number Publication Date
PL3279313T3 true PL3279313T3 (pl) 2021-05-31

Family

ID=41350492

Family Applications (2)

Application Number Title Priority Date Filing Date
PL17168855T PL3279313T3 (pl) 2009-09-28 2010-09-28 Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków
PL10768559T PL2483389T3 (pl) 2009-09-28 2010-09-28 Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL10768559T PL2483389T3 (pl) 2009-09-28 2010-09-28 Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków

Country Status (21)

Country Link
US (2) US20130052227A1 (pl)
EP (2) EP2483389B1 (pl)
JP (3) JP2013505716A (pl)
KR (1) KR101786025B1 (pl)
CN (2) CN107475168B (pl)
AU (1) AU2010299577B2 (pl)
CA (1) CA2775642C (pl)
CY (2) CY1118970T1 (pl)
DK (2) DK2483389T3 (pl)
ES (2) ES2846901T3 (pl)
GB (1) GB0917002D0 (pl)
HR (2) HRP20170845T1 (pl)
HU (1) HUE053188T2 (pl)
LT (2) LT3279313T (pl)
NZ (1) NZ599598A (pl)
PH (1) PH12012500629A1 (pl)
PL (2) PL3279313T3 (pl)
PT (2) PT3279313T (pl)
SI (2) SI2483389T1 (pl)
WO (1) WO2011036564A2 (pl)
ZA (1) ZA201202934B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
GB201017519D0 (en) 2010-10-15 2010-12-01 Novartis Vaccines Inst For Global Health S R L Vaccines
WO2014076714A2 (en) * 2012-11-19 2014-05-22 Indian Council Of Medical Research Novel immunogenic antigens of shigella
US9636390B2 (en) 2012-11-19 2017-05-02 Indian Council Of Medical Research Immunogenic antigens of shigella
AU2014239557B2 (en) 2013-03-15 2019-01-03 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to enteric pathogens
EP2870974A1 (en) 2013-11-08 2015-05-13 Novartis AG Salmonella conjugate vaccines
CN104974946B (zh) * 2014-04-08 2019-01-11 中国科学院天津工业生物技术研究所 耐高渗透压的重组大肠杆菌及其应用
CL2014001126A1 (es) * 2014-04-29 2014-08-29 Univ Chile Composición farmacéutica útil como vacuna contra bacterias escherichia coli productoras de shigatoxinas (stec), que comprende al menos un antígeno o una proteína de membrana externa inmunogénica o proteína inmunogénica asociada y conservada en cepas stec.
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN114796472A (zh) 2015-06-16 2022-07-29 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
CN105647892A (zh) * 2016-03-04 2016-06-08 江南大学 一种D-丙氨酰-D-丙氨酸羧肽酶dacA基因及应用
CN105647893A (zh) * 2016-03-04 2016-06-08 江南大学 一种D-丙氨酰-D-丙氨酸羧肽酶dacD基因及应用
KR102767638B1 (ko) 2016-05-03 2025-02-20 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법
US20170360881A1 (en) * 2016-06-17 2017-12-21 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
EP3263695A1 (en) 2016-06-29 2018-01-03 GlaxoSmithKline Biologicals SA Immunogenic compositions
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2019163785A1 (ja) * 2018-02-20 2019-08-29 株式会社山田養蜂場本社 膜小胞組成物の製造方法
ES3062841T3 (en) * 2018-07-24 2026-04-14 Wacker Chemie Ag New bacterial lpp-mutant and its use for secretory production of recombinant proteins
EP3725371A1 (en) * 2019-04-18 2020-10-21 BiOMVis Srl Method for the production of outer membrane vesicles and immunogenic compositions thereof
CN111363018B (zh) * 2020-03-26 2021-10-01 廊坊梅花生物技术开发有限公司 重组菌株及其在l-色氨酸制备中的应用
WO2022133289A2 (en) 2020-12-18 2022-06-23 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
GB202112149D0 (en) 2021-08-24 2021-10-06 Glaxosmithkline Biologicals Sa Shigellla vaccine
CN113897324B (zh) * 2021-10-13 2023-07-28 云南师范大学 一种用作抗锰剂的JcVIPP1重组大肠杆菌及其构建方法
GB202118913D0 (en) 2021-12-23 2022-02-09 Glaxosmithkline Biologicals Sa Method for preparing outer membrane vesicles
CN116855471B (zh) * 2023-09-04 2023-11-28 江苏申基生物科技有限公司 一种嘌呤核苷磷酸化酶突变体及其应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8205892D0 (sv) 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
US5916588A (en) 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US6090406A (en) 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
AU631377B2 (en) 1988-08-25 1992-11-26 Liposome Company, Inc., The Affinity associated vaccine
CA2017507C (en) 1989-05-25 1996-11-12 Gary Van Nest Adjuvant formulation comprising a submicron oil droplet emulsion
CA2138997C (en) 1992-06-25 2003-06-03 Jean-Paul Prieels Vaccine composition containing adjuvants
US5776468A (en) 1993-03-23 1998-07-07 Smithkline Beecham Biologicals (S.A.) Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A
WO1995011700A1 (en) 1993-10-29 1995-05-04 Pharmos Corp. Submicron emulsions as vaccine adjuvants
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6429199B1 (en) 1994-07-15 2002-08-06 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells
US5897475A (en) 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
GB9513261D0 (en) 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
US6887483B2 (en) * 1995-12-01 2005-05-03 University Of Iowa Research Foundation Non-toxic mutants of pathogenic gram-negative bacteria
DK1005368T3 (da) 1997-03-10 2010-01-04 Ottawa Hospital Res Inst Anvendelse af nukleinsyrer, der indeholder ikke-metyleret CpG dinukleotid i kombination med alun som hjælpestoffer
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US6080725A (en) 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
GB9712347D0 (en) 1997-06-14 1997-08-13 Smithkline Beecham Biolog Vaccine
AU1145699A (en) 1997-09-05 1999-03-22 Smithkline Beecham Biologicals (Sa) Oil in water emulsions containing saponins
GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
IL137809A0 (en) 1998-02-12 2001-10-31 American Cyanamid Co Pneumococcal and meningococcal vaccines formulated with interleukin-12
US6303114B1 (en) 1998-03-05 2001-10-16 The Medical College Of Ohio IL-12 enhancement of immune responses to T-independent antigens
US6562798B1 (en) 1998-06-05 2003-05-13 Dynavax Technologies Corp. Immunostimulatory oligonucleotides with modified bases and methods of use thereof
GB9817052D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Biolog Vaccine
WO2001025254A2 (en) * 1999-10-04 2001-04-12 University Of Maryland Biotechnology Institute Novel adjuvant comprising a lipopolysaccharide antagonist
US20010044416A1 (en) 2000-01-20 2001-11-22 Mccluskie Michael J. Immunostimulatory nucleic acids for inducing a Th2 immune response
AU2001294750C1 (en) 2000-09-26 2008-09-18 Idera Pharmaceuticals, Inc. Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
GB0103171D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
WO2003035836A2 (en) 2001-10-24 2003-05-01 Hybridon Inc. Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
US20060057160A1 (en) * 2002-08-02 2006-03-16 Ralph Biemans Vaccine composition
EP1608402B1 (en) 2003-03-24 2010-10-20 Intercell AG Improved vaccines
KR20110132416A (ko) 2004-04-05 2011-12-07 화이자 프로덕츠 인코포레이티드 미세유체화된 수중유 유화액 및 백신 조성물
AU2012207041A1 (en) 2005-02-18 2012-08-16 J. Craig Venter Institute, Inc. Proteins and nucleic acids from meningitis/sepsis-associated Escherichia Coli
JP2008530245A (ja) 2005-02-18 2008-08-07 ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド 尿路病原性菌株由来の抗原
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion

Also Published As

Publication number Publication date
US11339367B2 (en) 2022-05-24
BR112012006912A8 (pt) 2017-07-11
DK3279313T3 (da) 2021-01-25
EP3279313A2 (en) 2018-02-07
US20130052227A1 (en) 2013-02-28
GB0917002D0 (en) 2009-11-11
HRP20170845T1 (hr) 2017-08-11
EP2483389A2 (en) 2012-08-08
HUE053188T2 (hu) 2021-06-28
CN107475168A (zh) 2017-12-15
JP7023248B2 (ja) 2022-02-21
DK2483389T3 (en) 2017-07-10
CA2775642C (en) 2022-09-06
ES2632747T3 (es) 2017-09-15
JP2013505716A (ja) 2013-02-21
EP2483389B1 (en) 2017-05-03
CY1118970T1 (el) 2018-01-10
WO2011036564A2 (en) 2011-03-31
AU2010299577A1 (en) 2012-05-24
LT3279313T (lt) 2021-03-25
CN102906245A (zh) 2013-01-30
US20160289632A1 (en) 2016-10-06
SI2483389T1 (sl) 2017-08-31
HRP20210243T1 (hr) 2021-04-02
JP2016105736A (ja) 2016-06-16
BR112012006912A2 (pt) 2016-11-22
KR20120106729A (ko) 2012-09-26
WO2011036564A3 (en) 2011-08-04
PH12012500629A1 (en) 2012-10-22
SI3279313T1 (sl) 2021-02-26
ZA201202934B (en) 2012-12-27
CY1123774T1 (el) 2022-05-27
JP2019068864A (ja) 2019-05-09
AU2010299577B2 (en) 2015-09-03
CA2775642A1 (en) 2011-03-31
KR101786025B1 (ko) 2017-10-18
ES2846901T3 (es) 2021-07-30
CN102906245B (zh) 2017-08-18
EP3279313B1 (en) 2020-11-25
LT2483389T (lt) 2017-07-25
PT3279313T (pt) 2021-01-13
NZ599598A (en) 2013-08-30
PL2483389T3 (pl) 2017-09-29
CN107475168B (zh) 2026-01-09
EP3279313A3 (en) 2018-03-21
PT2483389T (pt) 2017-07-24

Similar Documents

Publication Publication Date Title
PL3279313T3 (pl) Szczepy shigella o nadmiernym wytwarzaniu pęcherzyków
DK2325522T3 (da) Stødisolerende struktur
DK2411442T4 (da) Umættet polyesterresin
DE112010004215A5 (de) Hydrostataktor
DK2430035T3 (da) Uracylspipooxetannukleosider
EP2420438A4 (en) SHIP
BRPI1008827A2 (pt) deisobutenizador
BRPI1014968A2 (pt) subalargador
BR112012001669A2 (pt) produção de elevação
DE112010002728A5 (de) Turboinhalator
DE112010004249A5 (de) Spindelaktor
DE112010001215A5 (de) Gurtaufrollersystem mit einsteuerglied
DE112009005323A5 (de) Hebelarmprüfmaschine
BRPI1008070A2 (pt) tricianoboratos
BR112012004964A2 (pt) girocóptero
DK2519512T3 (da) N1-acyl-5-fluorpyrimidinonderivater
EP2508411A4 (en) STRUCTURE
DK2483126T3 (da) Skinnekøretøj
DE112010004865T8 (de) Lamellennassreibkupplung
DE112010003255A5 (de) Fördergutverteiler
BRPI1010159A2 (pt) bistuti
LT2496735T (lt) Angliavandenilių gamyba
EP2390021A4 (en) HOLLOW ELEMENT
BRPI1016203A2 (pt) diferencial
IS8844A (is) Endurbætt flotvarpa