PL343435A1 - Glycine transport inhibitors - Google Patents

Glycine transport inhibitors

Info

Publication number: PL343435A1
Authority: PL; Poland
Prior art keywords: transport inhibitors; glycine transport; glycine; inhibitors; transport
Prior art date: 1998-03-06

Application number

PL99343435A

Other languages

English (en)

Inventor

Walter Herman Maria Lou Luyten

Frans Eduard Janssens

Ludo Edmond Josephine Kennis

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-06

Filing date

1999-02-26

Publication date

2001-08-13

1999-02-26 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-08-13 Publication of PL343435A1 publication Critical patent/PL343435A1/xx

Links

DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title 2
239000004471 Glycine Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

PL99343435A 1998-03-06 1999-02-26 Glycine transport inhibitors PL343435A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98200701		1998-03-06
PCT/EP1999/001309 WO1999044596A2 (en)	1998-03-06	1999-02-26	Glycine transport inhibitors

Publications (1)

Publication Number	Publication Date
PL343435A1 true PL343435A1 (en)	2001-08-13

Family

ID=8233444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL99343435A PL343435A1 (en)	1998-03-06	1999-02-26	Glycine transport inhibitors

Country Status (17)

Country	Link
EP (1)	EP1059922A2 (no)
JP (1)	JP2002505277A (no)
KR (1)	KR20010032968A (no)
CN (1)	CN1292698A (no)
AU (1)	AU3408999A (no)
BG (1)	BG104685A (no)
BR (1)	BR9907951A (no)
CA (1)	CA2322164A1 (no)
EE (1)	EE200000482A (no)
HR (1)	HRP20000523A2 (no)
HU (1)	HUP0101048A2 (no)
IL (1)	IL138228A0 (no)
NO (1)	NO20004431L (no)
PL (1)	PL343435A1 (no)
SK (1)	SK13082000A3 (no)
TR (1)	TR200002567T2 (no)
WO (1)	WO1999044596A2 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2003503403A (ja)	1999-06-28	2003-01-28	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	呼吸合胞体ウイルス複製阻害剤
UA73749C2 (en) *	1999-11-01	2005-09-15		Diarylenines
EP1296950A2 (en) *	2000-04-20	2003-04-02	NPS Allelix Corp.	Aminopiperidines for use as glyt-1 inhibitors
DE10040016A1 (de) *	2000-08-16	2002-02-28	Boehringer Ingelheim Pharma	Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
JP2004508312A (ja)	2000-09-08	2004-03-18	グリアテック　インコーポレイテッド	置換ヒドラジン誘導体
US20020082283A1 (en)	2000-09-14	2002-06-27	Gliatech, Inc.	Nitrogen-containing compounds and their use as glycine transport inhibitors
AR032653A1 (es)	2001-02-09	2003-11-19	Telik Inc	Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos.
US7030150B2 (en)	2001-05-11	2006-04-18	Trimeris, Inc.	Benzimidazole compounds and antiviral uses thereof
CN100522171C (zh)	2003-09-09	2009-08-05	弗·哈夫曼-拉罗切有限公司	作为甘氨酸摄取抑制剂、用于治疗精神病的1-苯甲酰基哌嗪衍生物
EP1663232B1 (en)	2003-09-09	2007-10-03	F. Hoffmann-La Roche Ag	1-(2-amino-benzoyl)-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses
WO2005058885A2 (en) *	2003-12-18	2005-06-30	Glaxo Group Limited	Piperidine derivatives and their use as glycine transporter inhibitors
TW200630337A (en)	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
PL1828154T3 (pl) *	2004-12-09	2009-10-30	Hoffmann La Roche	Pochodne fenylopiperazynometanonu
MX2007006896A (es)	2004-12-15	2007-06-26	Hoffmann La Roche	Fenil-metanonas bi- y triciclicas sustituidas como inhibidores del transportador 1 de glicina (glyt-1) para el tratamiento de la enfermedad de alzheimer.
GB0428233D0 (en) *	2004-12-23	2005-01-26	Glaxo Group Ltd	Compounds
PE20061156A1 (es)	2004-12-23	2006-12-16	Glaxo Group Ltd	Derivados de benzamida como agentes inhibidores del transportador de glicina
US7485637B2 (en)	2005-01-04	2009-02-03	Hoffmann-La Roche Inc.	Benzoyl-tetrahydropiperidine derivatives
CA2593453A1 (en) *	2005-01-06	2006-07-13	F. Hoffmann-La Roche Ag	Sulfanyl substituted phenyl methanones as glycine transporter 1 (glyt-1) inhibitors for the treatment of neurological and neuropsychiatric disorders
ATE472327T1 (de) *	2005-01-07	2010-07-15	Hoffmann La Roche	Ä4-(heteroaryl)piperazin-1-ylü-(2,5-substituier e phenyl)methanon-derivate als glycin-transporter 1 (glyt-1) hemmer zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
DE602006007682D1 (de)	2005-01-18	2009-08-20	Hoffmann La Roche	2,5-disubstituierte phenylmethanonderivative als glycintransporter-1-inhibitoren (glyt-1) zur behandlung von neurologischen und neuropsychiatrischen störungen
BRPI0607241A2 (pt)	2005-01-26	2009-08-25	Hoffmann La Roche	derivados de fenil metanona e o uso dos mesmos como inibidores do transportador de glicina 1
WO2006082001A1 (en)	2005-02-07	2006-08-10	F.Hoffmann-La Roche Ag	Heterocyclic substituted phenyl methanones as inhibitors of the glycine transporter 1
CN100341871C (zh) *	2005-06-03	2007-10-10	复旦大学	含哌啶结构的有机硫化合物，制备方法和应用
WO2007110449A1 (en)	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
WO2007118853A1 (en)	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use as blockers of calcium channels
TW200812963A (en)	2006-04-13	2008-03-16	Euro Celtique Sa	Benzenesulfonamide compounds and the use thereof
ES2389456T3 (es) *	2006-11-01	2012-10-26	Purdue Pharma Lp	Compuestos de fenilpropionamida y uso de los mismos
FR2910321B1 (fr)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) *	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	Emulsion comprenant au moins un retinoide et du peroxyde de benzole
WO2008124118A1 (en)	2007-04-09	2008-10-16	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use therof
WO2009040659A2 (en)	2007-09-28	2009-04-02	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
AU2008335788B2 (en) *	2007-12-12	2012-11-29	Amgen Inc.	Glycine transporter-1 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1140119A (en) *	1978-04-03	1983-01-25	Joseph Torremans	N-heterocyclyl-4-piperidinamines
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
WO1999025353A1 (en) *	1997-11-13	1999-05-27	Merck Sharp & Dohme Limited	Therapeutic uses of triazolo-pyridazine derivatives

1999
- 1999-02-26 EE EEP200000482A patent/EE200000482A/xx unknown
- 1999-02-26 HU HU0101048A patent/HUP0101048A2/hu unknown
- 1999-02-26 HR HR20000523A patent/HRP20000523A2/hr not_active Application Discontinuation
- 1999-02-26 SK SK1308-2000A patent/SK13082000A3/sk unknown
- 1999-02-26 KR KR1020007006315A patent/KR20010032968A/ko not_active Withdrawn
- 1999-02-26 TR TR2000/02567T patent/TR200002567T2/xx unknown
- 1999-02-26 CN CN998036471A patent/CN1292698A/zh active Pending
- 1999-02-26 WO PCT/EP1999/001309 patent/WO1999044596A2/en not_active Ceased
- 1999-02-26 AU AU34089/99A patent/AU3408999A/en not_active Abandoned
- 1999-02-26 IL IL13822899A patent/IL138228A0/xx unknown
- 1999-02-26 BR BR9907951-8A patent/BR9907951A/pt not_active Application Discontinuation
- 1999-02-26 PL PL99343435A patent/PL343435A1/xx not_active Application Discontinuation
- 1999-02-26 CA CA002322164A patent/CA2322164A1/en not_active Abandoned
- 1999-02-26 JP JP2000534198A patent/JP2002505277A/ja not_active Withdrawn
- 1999-02-26 EP EP99915541A patent/EP1059922A2/en not_active Withdrawn
2000
- 2000-08-11 BG BG104685A patent/BG104685A/xx unknown
- 2000-09-05 NO NO20004431A patent/NO20004431L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2322164A1 (en)	1999-09-10
TR200002567T2 (tr)	2000-11-21
EP1059922A2 (en)	2000-12-20
IL138228A0 (en)	2001-10-31
HUP0101048A2 (hu)	2001-10-28
BR9907951A (pt)	2001-01-30
AU3408999A (en)	1999-09-20
SK13082000A3 (sk)	2001-03-12
NO20004431D0 (no)	2000-09-05
WO1999044596A2 (en)	1999-09-10
WO1999044596A3 (en)	2000-02-17
EE200000482A (et)	2002-02-15
NO20004431L (no)	2000-10-30
CN1292698A (zh)	2001-04-25
HRP20000523A2 (en)	2001-02-28
JP2002505277A (ja)	2002-02-19
KR20010032968A (ko)	2001-04-25
BG104685A (en)	2001-04-30

Legal Events

Date	Code	Title	Description
2007-07-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
IL138228A0 (en)	2001-10-31	Glycine transport inhibitors
IL138227A0 (en)	2001-10-31	Glycine transport inhibitors
GB2333747B (en)	2002-05-22	Transport system
ZA98376B (en)	1998-07-23	Sulfamide-metalloprotease inhibitors
GB2321641B (en)	2001-04-04	Sulfamide-metalloprotease inhibitors
PL331338A1 (en)	1999-07-05	Thiosulphonamidic metaloprotease inhibitors
PL342516A1 (en)	2001-06-18	Phospholipase a2 inhibitors
GB9917793D0 (en)	1999-09-29	Peptide transport
IL147697A0 (en)	2002-08-14	Phosphate transport inhibitors
ZA983762B (en)	1998-11-06	Protease inhibitors
EP1067894A4 (en)	2004-09-08	PROTHEASEINHIBITOREN
IL152587A0 (en)	2003-05-29	Phosphate transport inhibitors
EP1079821A4 (en)	2001-08-29	PROTEASE INHIBITORS
AU2030999A (en)	1999-07-26	Glycine transport inhibitors
AU7131698A (en)	1999-11-08	Polyamine transport inhibitors
GB9825854D0 (en)	1999-01-20	Peptide
GB9814952D0 (en)	1998-09-09	Transport device
AU1998899A (en)	2000-06-26	Polyamine transport inhibitors
AU2599099A (en)	1999-08-30	Tricyclic compounds as glycine transport inhibitors
GB9803553D0 (en)	1998-04-15	Transporting devices
GB9717117D0 (en)	1997-10-22	Transport device
HK1031833A (en)	2001-06-29	Glycine transport inhibitors
HK1031879A (en)	2001-06-29	Glycine transport inhibitors
GB2341818B (en)	2001-09-19	Disc transport system
GB9821864D0 (en)	1998-12-02	Transport