PL3455216T3 - Pochodne pirydynylowe, kompozycje farmaceutyczne i ich zastosowania jako inhibitory aoc3 - Google Patents

Pochodne pirydynylowe, kompozycje farmaceutyczne i ich zastosowania jako inhibitory aoc3

Info

Publication number: PL3455216T3
Authority: PL; Poland
Prior art keywords: pharmaceutical compositions; pyridinyl derivatives; aoc3 inhibitors; aoc3; inhibitors
Prior art date: 2016-05-12

Application number

PL17721706T

Other languages

English (en)

Inventor

Andreas Blum

Cédrickx GODBOUT

Joerg P. Hehn

Stefan Peters

Original Assignee

Boehringer Ingelheim International Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-05-12

Filing date

2017-05-08

Publication date

2021-05-17

2017-05-08 Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh

2021-05-17 Publication of PL3455216T3 publication Critical patent/PL3455216T3/pl

Links

239000003112 inhibitor Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004076 pyridyl group Chemical group 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PL17721706T 2016-05-12 2017-05-08 Pochodne pirydynylowe, kompozycje farmaceutyczne i ich zastosowania jako inhibitory aoc3 PL3455216T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP16169356		2016-05-12
EP17721706.4A EP3455216B1 (en)	2016-05-12	2017-05-08	Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors
PCT/EP2017/060890 WO2017194453A1 (en)	2016-05-12	2017-05-08	Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors

Publications (1)

Publication Number	Publication Date
PL3455216T3 true PL3455216T3 (pl)	2021-05-17

Family

ID=55967162

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL17721706T PL3455216T3 (pl)	2016-05-12	2017-05-08	Pochodne pirydynylowe, kompozycje farmaceutyczne i ich zastosowania jako inhibitory aoc3

Country Status (32)

Country	Link
US (1)	US9926292B2 (pl)
EP (1)	EP3455216B1 (pl)
JP (1)	JP6639702B2 (pl)
KR (1)	KR20190003995A (pl)
CN (1)	CN109153664B (pl)
AR (1)	AR108462A1 (pl)
AU (1)	AU2017262707B2 (pl)
CA (1)	CA3023805A1 (pl)
CL (1)	CL2018003158A1 (pl)
CO (1)	CO2018012020A2 (pl)
CY (1)	CY1123744T1 (pl)
DK (1)	DK3455216T3 (pl)
EA (1)	EA037188B1 (pl)
ES (1)	ES2844926T3 (pl)
HR (1)	HRP20202078T1 (pl)
HU (1)	HUE053312T2 (pl)
IL (1)	IL262662B (pl)
JO (1)	JOP20170115B1 (pl)
LT (1)	LT3455216T (pl)
MA (1)	MA44965B1 (pl)
MX (1)	MX379327B (pl)
PE (1)	PE20190151A1 (pl)
PH (1)	PH12018502376B1 (pl)
PL (1)	PL3455216T3 (pl)
PT (1)	PT3455216T (pl)
RS (1)	RS61256B1 (pl)
SA (1)	SA518400393B1 (pl)
SG (1)	SG11201809687TA (pl)
SI (1)	SI3455216T1 (pl)
TW (1)	TWI746551B (pl)
UA (1)	UA121930C2 (pl)
WO (1)	WO2017194453A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111989103A (zh) *	2018-04-17	2020-11-24	勃林格殷格翰国际有限公司	药物组合物、其治疗方法和用途
CN112789277B (zh) *	2018-10-22	2022-11-04	广东东阳光药业有限公司	胍类衍生物及其用途
KR102812426B1 (ko)	2018-10-29	2025-05-26	베링거 인겔하임 인터내셔날 게엠베하	피리디닐 설폰아미드 유도체, 약제학적 조성물 및 이의 용도
US12213970B2 (en)	2018-10-29	2025-02-04	Boehringer Ingelheim International Gmbh	Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
AU2020377093B2 (en)	2019-10-29	2026-02-26	Eccogene Inc.	SSAO inhibitors and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19518073A1 (de) *	1995-05-17	1996-11-21	Hoechst Ag	Substituierte Benzyloxycarbonylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP1663204B1 (en) *	2003-08-29	2014-05-07	Exelixis, Inc.	C-kit modulators and methods of use
CN101031555A (zh) *	2004-07-27	2007-09-05	安斯泰来制药有限公司	具有vap－1抑制活性的噻唑衍生物
PL2479165T3 (pl) *	2009-09-16	2018-05-30	Astellas Pharma Inc.	Związek glicynowy
LT3002278T (lt)	2011-03-15	2017-06-26	Astellas Pharma Inc.	Guanidino junginys
AU2016301745B2 (en)	2015-08-06	2020-07-16	Ube Industries, Ltd.	Substituted guanidine derivative

2017
- 2017-05-08 EP EP17721706.4A patent/EP3455216B1/en active Active
- 2017-05-08 CN CN201780027576.9A patent/CN109153664B/zh active Active
- 2017-05-08 PL PL17721706T patent/PL3455216T3/pl unknown
- 2017-05-08 MX MX2018013701A patent/MX379327B/es unknown
- 2017-05-08 WO PCT/EP2017/060890 patent/WO2017194453A1/en not_active Ceased
- 2017-05-08 RS RS20201583A patent/RS61256B1/sr unknown
- 2017-05-08 US US15/588,739 patent/US9926292B2/en active Active
- 2017-05-08 HR HRP20202078TT patent/HRP20202078T1/hr unknown
- 2017-05-08 DK DK17721706.4T patent/DK3455216T3/da active
- 2017-05-08 SI SI201730584T patent/SI3455216T1/sl unknown
- 2017-05-08 HU HUE17721706A patent/HUE053312T2/hu unknown
- 2017-05-08 ES ES17721706T patent/ES2844926T3/es active Active
- 2017-05-08 LT LTEP17721706.4T patent/LT3455216T/lt unknown
- 2017-05-08 SG SG11201809687TA patent/SG11201809687TA/en unknown
- 2017-05-08 PT PT177217064T patent/PT3455216T/pt unknown
- 2017-05-08 CA CA3023805A patent/CA3023805A1/en active Pending
- 2017-05-08 PE PE2018002340A patent/PE20190151A1/es unknown
- 2017-05-08 MA MA44965A patent/MA44965B1/fr unknown
- 2017-05-08 AU AU2017262707A patent/AU2017262707B2/en not_active Ceased
- 2017-05-08 JP JP2018559351A patent/JP6639702B2/ja active Active
- 2017-05-08 KR KR1020187035976A patent/KR20190003995A/ko not_active Abandoned
- 2017-05-08 EA EA201892539A patent/EA037188B1/ru not_active IP Right Cessation
- 2017-05-08 UA UAA201812102A patent/UA121930C2/uk unknown
- 2017-05-11 AR ARP170101262A patent/AR108462A1/es not_active Application Discontinuation
- 2017-05-11 JO JOP/2017/0115A patent/JOP20170115B1/ar active
- 2017-05-11 TW TW106115558A patent/TWI746551B/zh not_active IP Right Cessation
2018
- 2018-10-29 IL IL262662A patent/IL262662B/en unknown
- 2018-11-06 CO CONC2018/0012020A patent/CO2018012020A2/es unknown
- 2018-11-07 SA SA518400393A patent/SA518400393B1/ar unknown
- 2018-11-08 CL CL2018003158A patent/CL2018003158A1/es unknown
- 2018-11-12 PH PH12018502376A patent/PH12018502376B1/en unknown
2021
- 2021-01-19 CY CY20211100039T patent/CY1123744T1/el unknown

Also Published As

Publication number	Publication date
CO2018012020A2 (es)	2018-11-13
EA037188B1 (ru)	2021-02-17
PE20190151A1 (es)	2019-01-22
HUE053312T2 (hu)	2021-07-28
US20170327483A1 (en)	2017-11-16
SG11201809687TA (en)	2018-11-29
JP2019519495A (ja)	2019-07-11
JOP20170115B1 (ar)	2021-08-17
KR20190003995A (ko)	2019-01-10
US9926292B2 (en)	2018-03-27
PH12018502376A1 (en)	2019-04-08
EP3455216B1 (en)	2020-11-04
PT3455216T (pt)	2021-01-18
AR108462A1 (es)	2018-08-22
MA44965B1 (fr)	2021-02-26
CN109153664B (zh)	2021-07-16
CA3023805A1 (en)	2017-11-16
NZ746586A (en)	2021-08-27
CN109153664A (zh)	2019-01-04
AU2017262707A1 (en)	2018-10-11
CL2018003158A1 (es)	2019-01-18
TW201805278A (zh)	2018-02-16
IL262662B (en)	2021-07-29
JP6639702B2 (ja)	2020-02-05
ES2844926T3 (es)	2021-07-23
EA201892539A1 (ru)	2019-06-28
MX2018013701A (es)	2019-05-02
LT3455216T (lt)	2021-01-11
CY1123744T1 (el)	2022-05-27
PH12018502376B1 (en)	2021-10-06
MX379327B (es)	2025-03-11
WO2017194453A1 (en)	2017-11-16
SI3455216T1 (sl)	2021-02-26
IL262662A (en)	2018-12-31
TWI746551B (zh)	2021-11-21
AU2017262707B2 (en)	2020-11-19
EP3455216A1 (en)	2019-03-20
UA121930C2 (uk)	2020-08-10
SA518400393B1 (ar)	2021-09-08
HRP20202078T1 (hr)	2021-02-19
MA44965A (fr)	2019-03-20
DK3455216T3 (da)	2021-01-18
RS61256B1 (sr)	2021-01-29

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