PL3484911T3 - Sposób oczyszczania PEGylowanej erytropoetyny - Google Patents

Sposób oczyszczania PEGylowanej erytropoetyny

Info

Publication number
PL3484911T3
PL3484911T3 PL17745145T PL17745145T PL3484911T3 PL 3484911 T3 PL3484911 T3 PL 3484911T3 PL 17745145 T PL17745145 T PL 17745145T PL 17745145 T PL17745145 T PL 17745145T PL 3484911 T3 PL3484911 T3 PL 3484911T3
Authority
PL
Poland
Prior art keywords
pegylated erythropoietin
purifying pegylated
purifying
erythropoietin
pegylated
Prior art date
Application number
PL17745145T
Other languages
English (en)
Inventor
Roberto Falkenstein
Bernhard SPENSBERGER
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3484911T3 publication Critical patent/PL3484911T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL17745145T 2016-07-15 2017-07-13 Sposób oczyszczania PEGylowanej erytropoetyny PL3484911T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16179755 2016-07-15
PCT/EP2017/067790 WO2018011381A1 (en) 2016-07-15 2017-07-13 Method for purifying pegylated erythropoietin
EP17745145.7A EP3484911B1 (en) 2016-07-15 2017-07-13 Method for purifying pegylated erythropoietin

Publications (1)

Publication Number Publication Date
PL3484911T3 true PL3484911T3 (pl) 2021-03-08

Family

ID=56497564

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17745145T PL3484911T3 (pl) 2016-07-15 2017-07-13 Sposób oczyszczania PEGylowanej erytropoetyny

Country Status (15)

Country Link
US (3) US20190300567A1 (pl)
EP (1) EP3484911B1 (pl)
JP (2) JP7177035B2 (pl)
KR (2) KR102470282B1 (pl)
CN (1) CN109415427A (pl)
AU (1) AU2017295037B2 (pl)
BR (1) BR112018076390A2 (pl)
ES (1) ES2841648T3 (pl)
HR (1) HRP20202077T1 (pl)
IL (1) IL264153B (pl)
MX (1) MX391087B (pl)
PL (1) PL3484911T3 (pl)
SG (1) SG11201811553UA (pl)
SI (1) SI3484911T1 (pl)
WO (1) WO2018011381A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3484911T3 (pl) * 2016-07-15 2021-03-08 F. Hoffmann-La Roche Ag Sposób oczyszczania PEGylowanej erytropoetyny

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
FR2646438B1 (fr) 1989-03-20 2007-11-02 Pasteur Institut Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
AU635844B2 (en) 1989-11-06 1993-04-01 Cell Genesys, Inc. Production of proteins using homologous recombination
KR0176693B1 (ko) 1989-12-22 1999-04-01 레지널드 디. 쇼트보그; 제롬 반 쥘렌 조절요소를 사용한 내인성 유전자의 발현을 변형시키는 방법
JPH04218000A (ja) 1990-02-13 1992-08-07 Kirin Amgen Inc 修飾ポリペプチド
JP3051145B2 (ja) 1990-08-28 2000-06-12 住友製薬株式会社 新規なポリエチレングリコール誘導体修飾ペプチド
DE4118912C1 (pl) 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
US5733761A (en) 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
ATE225801T1 (de) 1992-07-13 2002-10-15 Bionebraska Inc Verfahren zur modifizierung rekombinanter polypeptide
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
JPH08176133A (ja) * 1994-12-26 1996-07-09 Takeda Chem Ind Ltd Ｌ−アスコルビン酸の精製法
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
CN1260249C (zh) 1998-05-06 2006-06-21 基因技术股份有限公司 用离子交换层析纯化蛋白质
CN1376164A (zh) 1999-01-29 2002-10-23 霍夫曼-拉罗奇有限公司 Gcsf缀合物
PE20010288A1 (es) * 1999-07-02 2001-03-07 Hoffmann La Roche Derivados de eritropoyetina
CZ299516B6 (cs) 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
ATE336514T1 (de) 2000-02-11 2006-09-15 Merck Patent Gmbh Steigerung der zirkulierenden halbwertzeit von auf antikörpern basierenden fusionsproteinen
US20050100991A1 (en) 2001-04-12 2005-05-12 Human Genome Sciences, Inc. Albumin fusion proteins
CA2496060C (en) 2002-09-11 2015-08-04 Genentech, Inc. Protein purification by ion exchange chromatography
US7610156B2 (en) 2003-03-31 2009-10-27 Xencor, Inc. Methods for rational pegylation of proteins
US20050008649A1 (en) 2003-06-02 2005-01-13 University Of Miami Chimeric molecules and methods of use
AR067537A1 (es) * 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
EP3441402A1 (en) * 2007-10-30 2019-02-13 Genentech, Inc. Antibody purification by cation exchange chromatography
DE102008002209A1 (de) * 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur Aufreinigung von Erythropoietin
US20120172299A1 (en) * 2008-09-23 2012-07-05 F. Hoffmann-La Roche Ag Purification of erythropoietin
ES2576109T3 (es) * 2008-12-02 2016-07-05 Novo Nordisk Health Care Ag Purificación de polipéptidos
CN102711978B (zh) * 2010-01-08 2015-11-25 塔斯马尼亚大学 多孔聚合物整料、其制备方法及其用途
CN103118708B (zh) * 2010-09-14 2015-08-26 霍夫曼-拉罗奇有限公司 用于纯化聚乙二醇化的促红细胞生成素的方法
PL3484911T3 (pl) 2016-07-15 2021-03-08 F. Hoffmann-La Roche Ag Sposób oczyszczania PEGylowanej erytropoetyny

Also Published As

Publication number Publication date
IL264153B (en) 2021-09-30
AU2017295037B2 (en) 2021-07-22
KR102470282B1 (ko) 2022-11-24
ES2841648T3 (es) 2021-07-08
US20210155655A1 (en) 2021-05-27
KR102820834B1 (ko) 2025-06-13
EP3484911A1 (en) 2019-05-22
US20190300567A1 (en) 2019-10-03
AU2017295037A1 (en) 2019-01-24
HRP20202077T1 (hr) 2021-02-19
US11993630B2 (en) 2024-05-28
MX2018016033A (es) 2019-05-13
CA3027143A1 (en) 2018-01-18
IL264153A (en) 2019-02-28
MX391087B (es) 2025-03-21
EP3484911B1 (en) 2020-11-04
JP7177035B2 (ja) 2022-11-22
WO2018011381A1 (en) 2018-01-18
JP7530413B2 (ja) 2024-08-07
KR20190026759A (ko) 2019-03-13
US20250136639A1 (en) 2025-05-01
JP2019524726A (ja) 2019-09-05
BR112018076390A2 (pt) 2019-03-26
SI3484911T1 (sl) 2021-02-26
SG11201811553UA (en) 2019-01-30
CN109415427A (zh) 2019-03-01
JP2023015257A (ja) 2023-01-31
KR20220158870A (ko) 2022-12-01

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