PL352716A1 - Postacie polimorficzne krystalicznego cytrynianu azabicyklo[2.2.2.]oktano-3-aminy i zawierające je środki farmaceutyczne - Google Patents

Postacie polimorficzne krystalicznego cytrynianu azabicyklo[2.2.2.]oktano-3-aminy i zawierające je środki farmaceutyczne

Info

Publication number: PL352716A1
Authority: PL; Poland
Prior art keywords: octan; polymorphs; pharmaceutical compositions; amine citrate; azabicyclo
Prior art date: 1999-06-01

Application number

PL00352716A

Other languages

English (en)

Other versions

PL196046B1 (pl

Inventor

Michael James Castaldi

George Joseph Quallich

Lewin Theophilus Wint

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-01

Filing date

2000-05-18

Publication date

2003-09-08

2000-05-18 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2003-09-08 Publication of PL352716A1 publication Critical patent/PL352716A1/pl

2007-11-30 Publication of PL196046B1 publication Critical patent/PL196046B1/pl

Links

WCQNEVLYWBFPSQ-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;octan-3-amine Chemical compound CCCCCC(N)CC.OC(=O)CC(O)(C(O)=O)CC(O)=O WCQNEVLYWBFPSQ-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL00352716A 1999-06-01 2000-05-18 Postać krystaliczna monohydratu cytrynianu (2S,3S)-N-(2-metoksy-5-t-butylofenylo)metylo-2-difenylometylo-1-azabicyklo[2.2.2]oktano-3-aminy, środek farmaceutyczny, zastosowanie tej postaci krystalicznej i sposób wytwarzania tej postaci krystalicznej PL196046B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13699299P	1999-06-01	1999-06-01
PCT/IB2000/000665 WO2000073304A1 (en)	1999-06-01	2000-05-18	Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions

Publications (2)

Publication Number	Publication Date
PL352716A1 true PL352716A1 (pl)	2003-09-08
PL196046B1 PL196046B1 (pl)	2007-11-30

Family

ID=22475338

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00352716A PL196046B1 (pl)	1999-06-01	2000-05-18	Postać krystaliczna monohydratu cytrynianu (2S,3S)-N-(2-metoksy-5-t-butylofenylo)metylo-2-difenylometylo-1-azabicyklo[2.2.2]oktano-3-aminy, środek farmaceutyczny, zastosowanie tej postaci krystalicznej i sposób wytwarzania tej postaci krystalicznej

Country Status (48)

Country	Link
US (1)	US6255320B1 (pl)
EP (1)	EP1181290B1 (pl)
JP (1)	JP3830816B2 (pl)
KR (1)	KR100476606B1 (pl)
CN (1)	CN1146565C (pl)
AP (1)	AP2001002349A0 (pl)
AR (1)	AR033331A1 (pl)
AT (1)	ATE244239T1 (pl)
AU (1)	AU767334B2 (pl)
BG (1)	BG65240B1 (pl)
BR (1)	BR0011094A (pl)
CA (1)	CA2372238C (pl)
CO (1)	CO5170463A1 (pl)
CY (1)	CY2007011I1 (pl)
CZ (1)	CZ295819B6 (pl)
DE (1)	DE60003679T2 (pl)
DK (1)	DK1181290T3 (pl)
DZ (1)	DZ3050A1 (pl)
EA (1)	EA003731B1 (pl)
EC (1)	ECSP003508A (pl)
EE (1)	EE200100656A (pl)
ES (1)	ES2199825T3 (pl)
GT (1)	GT200000087A (pl)
HN (1)	HN2000000077A (pl)
HR (1)	HRP20010904A2 (pl)
HU (1)	HUP0201301A3 (pl)
IL (1)	IL146406A0 (pl)
MA (1)	MA26742A1 (pl)
MX (1)	MXPA01012325A (pl)
MY (1)	MY133508A (pl)
NO (1)	NO20015848L (pl)
NZ (1)	NZ515349A (pl)
OA (1)	OA11956A (pl)
PA (1)	PA8496101A1 (pl)
PE (1)	PE20010209A1 (pl)
PL (1)	PL196046B1 (pl)
PT (1)	PT1181290E (pl)
SI (1)	SI1181290T1 (pl)
SK (1)	SK285820B6 (pl)
SV (1)	SV2001000093A (pl)
TN (1)	TNSN00120A1 (pl)
TR (1)	TR200103473T2 (pl)
TW (1)	TWI285204B (pl)
UA (1)	UA66925C2 (pl)
UY (1)	UY26176A1 (pl)
WO (1)	WO2000073304A1 (pl)
YU (1)	YU81101A (pl)
ZA (1)	ZA200109775B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0507301A (pt) *	2004-01-30	2007-06-26	Pfizer Prod Inc	composições farmacêuticas de antagonistas do receptor de nuerocinina e ciclodextrina e métodos para melhor toleráncia no local de injeção
MXPA06007964A (es) *	2004-01-30	2007-01-26	Pfizer Prod Inc	Antagonistas del receptor nk-1 para mejorar la recuperacion de anestesia.
JP5021318B2 (ja) *	2004-01-30	2012-09-05	ファイザー・プロダクツ・インク	β−シクロデキストリンを液体投薬形態に用いて多用量製剤を達成するための抗菌性防腐剤
KR100812046B1 (ko) *	2004-02-02	2008-03-10	화이자 프로덕츠 인크.	1-(2ｓ,3ｓ)-2-벤즈히드릴-ｎ-(5-삼급-부틸-2-메톡시벤질)퀴누클리딘-3-아민의 제조 방법
SG11201507286QA (en) *	2013-03-15	2015-10-29	Pearl Therapeutics Inc	Methods and systems for conditioning of particulate crystalline materials
CN110577522B (zh) *	2018-06-07	2022-12-27	东莞市东阳光动物保健药品有限公司	马罗匹坦柠檬酸盐新晶型及其制备方法
CN112979639B (zh) *	2019-12-16	2025-08-08	凯默斯医药科技(上海)有限公司	一种马罗皮坦新晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA27776C2 (uk) *	1991-05-31	2000-10-16	Пфайзер Інк.	Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців
US5393762A (en) *	1993-06-04	1995-02-28	Pfizer Inc.	Pharmaceutical agents for treatment of emesis
US5576317A (en) *	1994-12-09	1996-11-19	Pfizer Inc.	NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis

2000
- 2000-05-08 US US09/566,307 patent/US6255320B1/en not_active Expired - Lifetime
- 2000-05-17 HN HN2000000077A patent/HN2000000077A/es unknown
- 2000-05-18 UA UA2001118214A patent/UA66925C2/uk unknown
- 2000-05-18 OA OA1200100318A patent/OA11956A/en unknown
- 2000-05-18 PL PL00352716A patent/PL196046B1/pl not_active IP Right Cessation
- 2000-05-18 EA EA200101108A patent/EA003731B1/ru active Protection Beyond IP Right Term
- 2000-05-18 DE DE60003679T patent/DE60003679T2/de not_active Expired - Lifetime
- 2000-05-18 ES ES00925528T patent/ES2199825T3/es not_active Expired - Lifetime
- 2000-05-18 AU AU44248/00A patent/AU767334B2/en not_active Expired
- 2000-05-18 NZ NZ515349A patent/NZ515349A/xx unknown
- 2000-05-18 TR TR2001/03473T patent/TR200103473T2/xx unknown
- 2000-05-18 WO PCT/IB2000/000665 patent/WO2000073304A1/en not_active Ceased
- 2000-05-18 PT PT00925528T patent/PT1181290E/pt unknown
- 2000-05-18 EP EP00925528A patent/EP1181290B1/en not_active Expired - Lifetime
- 2000-05-18 YU YU81101A patent/YU81101A/sh unknown
- 2000-05-18 HU HU0201301A patent/HUP0201301A3/hu unknown
- 2000-05-18 SI SI200030161T patent/SI1181290T1/xx unknown
- 2000-05-18 CZ CZ20014269A patent/CZ295819B6/cs not_active IP Right Cessation
- 2000-05-18 CN CNB008082782A patent/CN1146565C/zh not_active Expired - Lifetime
- 2000-05-18 IL IL14640600A patent/IL146406A0/xx not_active IP Right Cessation
- 2000-05-18 HR HR20010904A patent/HRP20010904A2/hr not_active Application Discontinuation
- 2000-05-18 MX MXPA01012325A patent/MXPA01012325A/es unknown
- 2000-05-18 CA CA002372238A patent/CA2372238C/en not_active Expired - Lifetime
- 2000-05-18 DK DK00925528T patent/DK1181290T3/da active
- 2000-05-18 AP APAP/P/2001/002349A patent/AP2001002349A0/en unknown
- 2000-05-18 AT AT00925528T patent/ATE244239T1/de not_active IP Right Cessation
- 2000-05-18 SK SK1733-2001A patent/SK285820B6/sk not_active IP Right Cessation
- 2000-05-18 JP JP2001500629A patent/JP3830816B2/ja not_active Expired - Lifetime
- 2000-05-18 BR BR0011094-9A patent/BR0011094A/pt not_active Application Discontinuation
- 2000-05-18 KR KR10-2001-7015494A patent/KR100476606B1/ko not_active Expired - Fee Related
- 2000-05-18 EE EEP200100656A patent/EE200100656A/xx unknown
- 2000-05-23 PA PA20008496101A patent/PA8496101A1/es unknown
- 2000-05-26 TW TW089110206A patent/TWI285204B/zh not_active IP Right Cessation
- 2000-05-26 CO CO00039195A patent/CO5170463A1/es not_active Application Discontinuation
- 2000-05-29 UY UY26176A patent/UY26176A1/es not_active Application Discontinuation
- 2000-05-30 MY MYPI20002409A patent/MY133508A/en unknown
- 2000-05-30 PE PE2000000520A patent/PE20010209A1/es not_active Application Discontinuation
- 2000-05-30 AR ARP000102663A patent/AR033331A1/es active IP Right Grant
- 2000-05-31 SV SV2000000093A patent/SV2001000093A/es unknown
- 2000-05-31 TN TNTNSN00120A patent/TNSN00120A1/fr unknown
- 2000-05-31 MA MA25997A patent/MA26742A1/fr unknown
- 2000-05-31 DZ DZ000101A patent/DZ3050A1/xx active
- 2000-05-31 GT GT200000087A patent/GT200000087A/es unknown
- 2000-06-01 EC EC2000003508A patent/ECSP003508A/es unknown
2001
- 2001-11-28 ZA ZA200109775A patent/ZA200109775B/en unknown
- 2001-11-30 NO NO20015848A patent/NO20015848L/no not_active Application Discontinuation
- 2001-12-10 BG BG106204A patent/BG65240B1/bg unknown
2007
- 2007-03-27 CY CY2007011C patent/CY2007011I1/el unknown

Also Published As

Publication number	Publication date
PL196046B1 (pl)	2007-11-30
EP1181290B1 (en)	2003-07-02
JP2003501354A (ja)	2003-01-14
ATE244239T1 (de)	2003-07-15
IL146406A0 (en)	2002-07-25
CZ20014269A3 (cs)	2002-04-17
TWI285204B (en)	2007-08-11
DE60003679T2 (de)	2004-05-27
EA200101108A1 (ru)	2002-04-25
BR0011094A (pt)	2002-03-19
CY2007011I2 (el)	2010-07-28
DZ3050A1 (fr)	2004-03-27
PA8496101A1 (es)	2002-07-30
SK17332001A3 (sk)	2002-07-02
HUP0201301A3 (en)	2002-10-28
UY26176A1 (es)	2000-12-29
HK1046284A1 (en)	2003-01-03
NO20015848L (no)	2001-12-18
US6255320B1 (en)	2001-07-03
DE60003679D1 (de)	2003-08-07
CN1146565C (zh)	2004-04-21
AU767334B2 (en)	2003-11-06
SK285820B6 (sk)	2007-09-06
EE200100656A (et)	2003-02-17
ES2199825T3 (es)	2004-03-01
WO2000073304A1 (en)	2000-12-07
SV2001000093A (es)	2001-11-08
PT1181290E (pt)	2003-09-30
AR033331A1 (es)	2003-12-17
CN1353711A (zh)	2002-06-12
OA11956A (en)	2006-04-13
NO20015848D0 (no)	2001-11-30
DK1181290T3 (da)	2003-09-29
ECSP003508A (es)	2002-02-25
TR200103473T2 (tr)	2002-04-22
MY133508A (en)	2007-11-30
KR20020010688A (ko)	2002-02-04
CA2372238C (en)	2006-12-19
CY2007011I1 (el)	2010-07-28
HRP20010904A2 (en)	2003-02-28
HUP0201301A2 (en)	2002-08-28
NZ515349A (en)	2004-03-26
YU81101A (sh)	2004-07-15
HN2000000077A (es)	2001-02-02
KR100476606B1 (ko)	2005-03-18
CA2372238A1 (en)	2000-12-07
CZ295819B6 (cs)	2005-11-16
BG106204A (en)	2002-07-31
JP3830816B2 (ja)	2006-10-11
TNSN00120A1 (fr)	2005-11-10
MXPA01012325A (es)	2002-07-22
MA26742A1 (fr)	2004-12-20
AU4424800A (en)	2000-12-18
SI1181290T1 (en)	2003-12-31
GT200000087A (es)	2001-11-22
EP1181290A1 (en)	2002-02-27
UA66925C2 (uk)	2004-06-15
AP2001002349A0 (en)	2001-12-31
PE20010209A1 (es)	2001-03-01
EA003731B1 (ru)	2003-08-28
BG65240B1 (bg)	2007-09-28
ZA200109775B (en)	2002-11-28
CO5170463A1 (es)	2002-06-27

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Legal Events

Date	Code	Title	Description
2011-07-29	LAPS	Decisions on the lapse of the protection rights	Effective date: 20100518