PL353373A1 - Zastosowanie agonistów receptorów GABA(B) i ich farmaceutycznie dopuszczalnych pochodnych w leczeniu uzależnionych od nikotyny pacjentów - Google Patents

Zastosowanie agonistów receptorów GABA(B) i ich farmaceutycznie dopuszczalnych pochodnych w leczeniu uzależnionych od nikotyny pacjentów

Info

Publication number: PL353373A1
Authority: PL; Poland
Prior art keywords: agonists; therapy; pharmaceutically acceptable; receptors; gaba
Prior art date: 1999-07-30

Application number

PL00353373A

Other languages

English (en)

Other versions

PL196334B1 (pl

Inventor

Gian Luigi Gessa

Giancarlo Colombo

Luca Pani

Walter Fratta

Original Assignee

L.Molteni & C.Dei Fratelli Alitti Societa' Di Esercizio S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-30

Filing date

2000-06-30

Publication date

2003-11-17

2000-06-30 Application filed by L.Molteni & C.Dei Fratelli Alitti Societa' Di Esercizio S.P.A. filed Critical L.Molteni & C.Dei Fratelli Alitti Societa' Di Esercizio S.P.A.

2003-11-17 Publication of PL353373A1 publication Critical patent/PL353373A1/pl

2007-12-31 Publication of PL196334B1 publication Critical patent/PL196334B1/pl

Links

SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 2
239000000556 agonist Substances 0.000 title abstract 2
229960002715 nicotine Drugs 0.000 title abstract 2
SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 2
238000002560 therapeutic procedure Methods 0.000 title abstract 2
230000001419 dependent effect Effects 0.000 title 1
230000000391 smoking effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Addiction (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

PL353373A 1999-07-30 2000-06-30 Zastosowanie agonistów receptorów GABA B i ich farmaceutycznie dopuszczalnych pochodnych w terapii abstynencji nikotynowej u uzależnionych od nikotyny pacjentów PL196334B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1999MI001715A IT1313585B1 (it)	1999-07-30	1999-07-30	Uso di agonisti dei recettori gabab per la terapia di mantenimentodell'astinenza da nicotina in soggetti nicotino-dipendenti.
PCT/EP2000/006120 WO2001008675A1 (en)	1999-07-30	2000-06-30	Use of agonists of gabab receptors and pharmaceutically acceptable derivates thereof, in the therapy of maintaining nicotine abstinence-dependent patients

Publications (2)

Publication Number	Publication Date
PL353373A1 true PL353373A1 (pl)	2003-11-17
PL196334B1 PL196334B1 (pl)	2007-12-31

Family

ID=11383467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL353373A PL196334B1 (pl)	1999-07-30	2000-06-30	Zastosowanie agonistów receptorów GABA B i ich farmaceutycznie dopuszczalnych pochodnych w terapii abstynencji nikotynowej u uzależnionych od nikotyny pacjentów

Country Status (16)

Country	Link
EP (1)	EP1202727B1 (pl)
CN (1)	CN1176650C (pl)
AT (1)	ATE285763T1 (pl)
AU (1)	AU6153400A (pl)
CA (1)	CA2379752C (pl)
DE (1)	DE60017147T2 (pl)
DK (1)	DK1202727T3 (pl)
ES (1)	ES2235913T3 (pl)
HK (1)	HK1046849B (pl)
IL (2)	IL147876A0 (pl)
IT (1)	IT1313585B1 (pl)
PL (1)	PL196334B1 (pl)
PT (1)	PT1202727E (pl)
RU (1)	RU2262352C2 (pl)
SI (1)	SI1202727T1 (pl)
WO (1)	WO2001008675A1 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2354120A1 (en)	2003-08-20	2011-08-10	XenoPort, Inc.	Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
AU2004267100B2 (en) *	2003-08-20	2010-10-07	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US7566738B2 (en)	2004-11-03	2009-07-28	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en)	2004-11-03	2009-02-24	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2008033572A1 (en)	2006-09-15	2008-03-20	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
JP4498407B2 (ja)	2006-12-22	2010-07-07	キヤノン株式会社	プロセスカートリッジ、電子写真画像形成装置、及び、電子写真感光体ドラムユニット
WO2009094563A2 (en)	2008-01-25	2009-07-30	Xenoport, Inc.	Crystalline form of calcium-salts of (3s)-aminomethyl-b-methyl-hexanoic acids and methods of use
CA2710538A1 (en)	2008-01-25	2009-07-30	Xenoport, Inc.	Crystalline form of a (3s)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
WO2009094577A2 (en)	2008-01-25	2009-07-30	Xenoport, Inc.	Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
WO2010017504A1 (en)	2008-08-07	2010-02-11	Xenoport, Inc.	Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
WO2010017498A1 (en)	2008-08-07	2010-02-11	Xenoport, Inc.	Methods of synthesizing n-hydroxysuccinimidyl carbonates
US10071068B2 (en)	2009-03-03	2018-09-11	Xenoport, Inc.	Sustained release oral dosage forms of an R-baclofen prodrug
EP2419401A2 (en)	2009-04-17	2012-02-22	XenoPort, Inc.	GAMMA-AMINO-BUTYRIC ACID DERIVATIVES AS GABAb RECEPTOR LIGANDS
WO2011081558A1 (ru) *	2009-08-21	2011-07-07	Komissarov Jury Vladimirovich	Курительное устройство для отказа от табачного курения
US8580850B2 (en)	2011-08-11	2013-11-12	Xenoport, Inc.	Anhydrous and hemihydrate crystalline forms of an (R)-baclofen prodrug, methods of synthesis and methods of use
EP3761979A4 (en) *	2018-04-06	2021-06-30	Ovid Therapeutics Inc.	USE OF GABOXADOL TO TREAT SUBSTANCE ABUSE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4126684A (en) *	1976-02-11	1978-11-21	Ciba-Geigy Corporation	4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
US5073539A (en) *	1990-01-22	1991-12-17	Ciba-Geigy Corporation	Transdermal administration of zwitterionic drugs
US5760049A (en) *	1997-02-21	1998-06-02	Synapse Pharmaceuticals International, Inc.	Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
US6541520B1 (en) *	1998-08-05	2003-04-01	Brookhaven Science Associates	Treatment of addiction and addiction-related behavior
RU2132203C1 (ru) *	1998-09-03	1999-06-27	Шакирзянов Галимзян Закирович	Способ лечения табачной зависимости и антитабачный комбинированный препарат

1999
- 1999-07-30 IT IT1999MI001715A patent/IT1313585B1/it active
2000
- 2000-06-30 RU RU2002105375/15A patent/RU2262352C2/ru active
- 2000-06-30 IL IL14787600A patent/IL147876A0/xx active IP Right Grant
- 2000-06-30 HK HK02107911.9A patent/HK1046849B/en not_active IP Right Cessation
- 2000-06-30 CN CNB00811031XA patent/CN1176650C/zh not_active Expired - Lifetime
- 2000-06-30 CA CA002379752A patent/CA2379752C/en not_active Expired - Fee Related
- 2000-06-30 PL PL353373A patent/PL196334B1/pl unknown
- 2000-06-30 EP EP00947901A patent/EP1202727B1/en not_active Expired - Lifetime
- 2000-06-30 DK DK00947901T patent/DK1202727T3/da active
- 2000-06-30 WO PCT/EP2000/006120 patent/WO2001008675A1/en not_active Ceased
- 2000-06-30 AU AU61534/00A patent/AU6153400A/en not_active Abandoned
- 2000-06-30 SI SI200030632T patent/SI1202727T1/xx unknown
- 2000-06-30 PT PT00947901T patent/PT1202727E/pt unknown
- 2000-06-30 DE DE60017147T patent/DE60017147T2/de not_active Expired - Lifetime
- 2000-06-30 AT AT00947901T patent/ATE285763T1/de active
- 2000-06-30 ES ES00947901T patent/ES2235913T3/es not_active Expired - Lifetime
2002
- 2002-01-28 IL IL147876A patent/IL147876A/en unknown

Also Published As

Publication number	Publication date
IL147876A0 (en)	2002-08-14
PT1202727E (pt)	2005-05-31
AU6153400A (en)	2001-02-19
WO2001008675A1 (en)	2001-02-08
DK1202727T3 (da)	2005-05-09
EP1202727A1 (en)	2002-05-08
CN1176650C (zh)	2004-11-24
ITMI991715A1 (it)	2001-01-30
DE60017147T2 (de)	2006-01-12
HK1046849A1 (en)	2003-01-30
IL147876A (en)	2007-06-17
ITMI991715A0 (it)	1999-07-30
CA2379752A1 (en)	2001-02-08
ATE285763T1 (de)	2005-01-15
ES2235913T3 (es)	2005-07-16
CN1377265A (zh)	2002-10-30
RU2262352C2 (ru)	2005-10-20
SI1202727T1 (pl)	2005-08-31
EP1202727B1 (en)	2004-12-29
HK1046849B (en)	2005-07-15
IT1313585B1 (it)	2002-09-09
CA2379752C (en)	2008-05-27
PL196334B1 (pl)	2007-12-31
DE60017147D1 (de)	2005-02-03

Publication	Publication Date	Title
IL147876A0 (en)	2002-08-14	Use of agonists of gabab receptors and pharmaceutically acceptable derivatives thereof, in the therapy of maintaining nicotine abstinence-dependent patients
IL195723A (en)	2010-12-30	Use of p53 inhibitors for the preparation of medicament
RU94040387A (ru)	1996-10-20	Композиция, способствующая прекращению курения, никотиносодержащий распыляемый раствор, способ снижения потребности в курении табака, способ замены курения табака
MY146868A (en)	2012-09-28	Solid oral dosage forms of valsartan
MY130619A (en)	2007-07-31	Pharmaceutical formulations of 5,7,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
ATE264102T1 (de)	2004-04-15	Nicotin enthaltende pharmazeutische zusammensetzungen mit schneller transmukosaler absorption
AU1079701A (en)	2001-05-08	Oral transmucosal drug dosage using solid solution
BR0308137A (pt)	2005-01-04	Formulações de droga de liberação constante contendo um peptìdeo veìculo
WO1999030718A3 (en)	1999-09-10	PROSTAGLANDIN E2/F2α COMBINATION FOR TREATING IMPOTENCE AND ENHANCING SEXUAL AROUSAL
EA200001049A1 (ru)	2001-04-23	Новые способы лечения нервных расстройств
WO2001045715A3 (en)	2002-03-14	Combinations of an adenosine a1 agonist with an opioid and their use in the treatment of pain
IL136415A (en)	2005-03-20	Transmucosal formulations of levosimendan
AU2204701A (en)	2001-07-03	Formulations of adenosine a1 agonists
TW200517119A (en)	2005-06-01	Method of treatment using interferon-tau
MXPA01007952A (es)	2004-03-26	Formulaciones a base de l-arginina para tratar enfermedades, y metodos para usarlas.
AU9028098A (en)	1999-03-16	Combinations of endometrial sparing progestins and endometrial atrophizing progestins with estrogens, in oral contraception
AU2203101A (en)	2001-07-03	Formulations of adenosine a1 agonists
IL177764A0 (en)	2007-03-08	Opioid delivery system
MD1568G2 (ro)	2001-06-30	Metodă de tratament al bolii arşilor în perioada şocului combustional
MY127600A (en)	2006-12-29	Solid oral dosage forms of valsartan