PL353645A1 - Nowe aminobenzofenonyNowe aminobenzofenony - Google Patents

Nowe aminobenzofenonyNowe aminobenzofenony

Info

Publication number: PL353645A1
Authority: PL; Poland
Prior art keywords: alkyl; similar; different substituents; represents hydrogen; formula
Prior art date: 1999-07-16

Application number

PL00353645A

Other languages

English (en)

Inventor

Erik RytterOttosen Erik Rytter Ottosen

FredrikBjorkling Fredrik Bjorkling

Original Assignee

Leo Pharma A/Sleo Pharma A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-16

Filing date

2000-07-11

Publication date

2003-12-01

2000-07-11 Application filed by Leo Pharma A/Sleo Pharma A/S filed Critical Leo Pharma A/Sleo Pharma A/S

2003-12-01 Publication of PL353645A1 publication Critical patent/PL353645A1/pl

Links

MAOBFOXLCJIFLV-UHFFFAOYSA-N (2-aminophenyl)-phenylmethanone Chemical class NC1=CC=CC=C1C(=O)C1=CC=CC=C1 MAOBFOXLCJIFLV-UHFFFAOYSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical group 0.000 abstract 3
125000001424 substituent group Chemical group 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
150000007513 acids Chemical class 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
-1 hydroxy, mercapto Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Virology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)
Ophthalmology & Optometry (AREA)
AIDS & HIV (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

PL00353645A 1999-07-16 2000-07-11 Nowe aminobenzofenonyNowe aminobenzofenony PL353645A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US14406599P	1999-07-16	1999-07-16

Publications (1)

Publication Number	Publication Date
PL353645A1 true PL353645A1 (pl)	2003-12-01

Family

ID=22506899

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00353645A PL353645A1 (pl)	1999-07-16	2000-07-11	Nowe aminobenzofenonyNowe aminobenzofenony

Country Status (18)

Country	Link
US (1)	US6624199B1 (pl)
EP (1)	EP1202954B1 (pl)
JP (1)	JP2003505359A (pl)
KR (1)	KR20020013961A (pl)
CN (1)	CN1231459C (pl)
AT (1)	ATE251117T1 (pl)
AU (1)	AU768473B2 (pl)
CA (1)	CA2379316A1 (pl)
DE (1)	DE60005689T2 (pl)
DK (1)	DK1202954T3 (pl)
ES (1)	ES2204639T3 (pl)
HK (1)	HK1048304B (pl)
HU (1)	HUP0201910A3 (pl)
NZ (1)	NZ516824A (pl)
PL (1)	PL353645A1 (pl)
PT (1)	PT1202954E (pl)
RU (1)	RU2243964C2 (pl)
WO (1)	WO2001005744A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL356049A1 (pl) *	1999-12-06	2004-06-14	Leo Pharma A/S	Aminobenzofenony jako inhibitory IL-1beta i TNF-alfa
RU2270194C2 (ru)	2000-05-22	2006-02-20	Лео Фарма А/С	Бензофеноны как ингибиторы il-1бета и tnf-альфа, фармацевтическая композиция и способ лечения
GB0107368D0 (en) *	2001-03-23	2001-05-16	Novartis Ag	Organic compounds
AU2002333193A1 (en) *	2001-08-15	2003-03-03	Leo Pharma A/S	A pharmaceutical composition for dermal application
IL160442A0 (en)	2001-08-28	2004-07-25	Leo Pharma As	Novel aminobenzophenones
US20030225089A1 (en) *	2002-04-10	2003-12-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
ES2278170T3 (es)	2002-07-09	2007-08-01	BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG	Composiciones farmaceuticas de anticolinergicos e inhibidores de la quinasa p38 en el tratamiento de enfermedades respiratorias.
PT1658263E (pt) *	2003-07-24	2010-09-06	Leo Pharma As	Novos compostos de aminobenzofenona
WO2005110422A2 (en)	2004-05-19	2005-11-24	Boehringer Ingelheim International Gmbh	Treatment of diseases associated with altered level of amyloid beta peptides
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
AU2005316034B2 (en)	2004-12-13	2012-01-19	Leo Pharma A/S	Triazole substituted aminobenzophenone compounds
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
FR2894821B1 (fr) *	2005-12-15	2008-02-29	Galderma Res & Dev	Compositions comprenant au moins un compose retinoide et au moins un compose anti-irritant et leurs utilisations
EP1992344A1 (en)	2007-05-18	2008-11-19	Institut Curie	P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
EP2206534A1 (de)	2008-10-09	2010-07-14	c-a-i-r biosciences GmbH	Dibenzocycloheptanonderivate und pharmazeutische Mittel, welche diese Verbindungen enthalten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9701453D0 (en) *	1997-01-24	1997-03-12	Leo Pharm Prod Ltd	Aminobenzophenones

2000
- 2000-07-11 JP JP2001511405A patent/JP2003505359A/ja active Pending
- 2000-07-11 HK HK03100579.6A patent/HK1048304B/zh not_active IP Right Cessation
- 2000-07-11 DE DE60005689T patent/DE60005689T2/de not_active Expired - Fee Related
- 2000-07-11 ES ES00943698T patent/ES2204639T3/es not_active Expired - Lifetime
- 2000-07-11 US US10/030,965 patent/US6624199B1/en not_active Expired - Fee Related
- 2000-07-11 EP EP00943698A patent/EP1202954B1/en not_active Expired - Lifetime
- 2000-07-11 AT AT00943698T patent/ATE251117T1/de not_active IP Right Cessation
- 2000-07-11 DK DK00943698T patent/DK1202954T3/da active
- 2000-07-11 PL PL00353645A patent/PL353645A1/pl not_active Application Discontinuation
- 2000-07-11 CN CNB008115028A patent/CN1231459C/zh not_active Expired - Fee Related
- 2000-07-11 NZ NZ516824A patent/NZ516824A/en unknown
- 2000-07-11 CA CA002379316A patent/CA2379316A1/en not_active Abandoned
- 2000-07-11 HU HU0201910A patent/HUP0201910A3/hu unknown
- 2000-07-11 PT PT00943698T patent/PT1202954E/pt unknown
- 2000-07-11 KR KR1020027000669A patent/KR20020013961A/ko not_active Ceased
- 2000-07-11 RU RU2002103862/04A patent/RU2243964C2/ru not_active IP Right Cessation
- 2000-07-11 AU AU58067/00A patent/AU768473B2/en not_active Ceased
- 2000-07-11 WO PCT/DK2000/000384 patent/WO2001005744A1/en not_active Ceased

Also Published As

Publication number	Publication date
ATE251117T1 (de)	2003-10-15
ES2204639T3 (es)	2004-05-01
JP2003505359A (ja)	2003-02-12
RU2243964C2 (ru)	2005-01-10
CN1231459C (zh)	2005-12-14
HUP0201910A2 (hu)	2002-12-28
DE60005689D1 (de)	2003-11-06
US6624199B1 (en)	2003-09-23
KR20020013961A (ko)	2002-02-21
HK1048304B (zh)	2006-04-21
WO2001005744A1 (en)	2001-01-25
HUP0201910A3 (en)	2006-03-28
NZ516824A (en)	2004-03-26
CA2379316A1 (en)	2001-01-25
HK1048304A1 (en)	2003-03-28
AU768473B2 (en)	2003-12-11
PT1202954E (pt)	2004-02-27
AU5806700A (en)	2001-02-05
DE60005689T2 (de)	2004-08-05
EP1202954A1 (en)	2002-05-08
EP1202954B1 (en)	2003-10-01
CN1368950A (zh)	2002-09-11
DK1202954T3 (da)	2004-02-09

Legal Events

Date	Code	Title	Description
2009-02-27	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL353645A1 (pl)	2003-12-01	Nowe aminobenzofenonyNowe aminobenzofenony
TW364903B (en)	1999-07-21	Halogenopyrimidines
TWI266761B (en)	2006-11-21	Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
TW328086B (en)	1998-03-11	Biphenylamides, compositions comprising them and the preparation and use thereof
GB9801690D0 (en)	1998-03-25	Therapeutic agents
DE60112974D1 (en)	2005-09-29	Carbolinderivate
NZ518144A (en)	2004-04-30	Piperazine Compounds
YU26800A (sh)	2002-12-10	Hemijska jedinjenja
MX9700883A (es)	1997-08-30	Derivados sustituidos de la quinazolina.
MXPA02011466A (es)	2003-04-25	Derivados de fenilglicina..
DE60216233D1 (en)	2007-01-04	Carbolinderivate
DE60014393D1 (de)	2004-11-04	Aminobenzophenone als inhibitoren von il-1beta und tnf-alpha
AU2001266575A1 (en)	2002-01-08	Chemical compounds
PT1021405E (pt)	2003-02-28	Derivados de azetidinona para o tratamento de infeccoes de hcmv
IL150329A0 (en)	2002-12-01	2-(1h-indol-3-yl)-2-oxo-acetamides with antitumor activity
AP2002002466A0 (en)	2002-06-30	3-heterocycliylpropanohydroxamic acid PCP INHIBITORS.
MXPA02012470A (es)	2004-01-26	Inhibidores de fosfodiesterasa especificos para gmp ciclico.
EP1357124A4 (en)	2004-02-04	HETEROCYCLIC COMPOUNDS AND COMPOSITIONS IMPROVING CEREBRAL FUNCTIONS CONTAINING THESE AS ACTIVE INGREDIENTS
MXPA02012472A (es)	2004-01-26	Compuestos quimicos.
SI1377574T1 (pl)	2005-08-31
HRP20050082A2 (en)	2005-06-30	6-amino-1h-indazole and 4-aminobenzofuran compounds as phosphodiesterase 4 inhibitors
MXPA03003971A (es)	2004-02-12	Derivados de indol como inhibidores de pde5.
MXPA02007973A (es)	2005-10-05	Compuestos de aminoacidos y su uso como inhibidores de nep, ace y ece.
MXPA05006957A (es)	2005-09-30	Nuevos derivados de fosforamida.
MXPA03000887A (es)	2004-04-05	Derivados heterociclicos fusionados como inhibidores de fosfodiesterasa.