PL3539551T3 - Sposób leczenia zaburzeń związanych z receptorem melanokortyny 4 u heterozygotycznych nosicieli - Google Patents
Sposób leczenia zaburzeń związanych z receptorem melanokortyny 4 u heterozygotycznych nosicieliInfo
- Publication number
- PL3539551T3 PL3539551T3 PL19158126T PL19158126T PL3539551T3 PL 3539551 T3 PL3539551 T3 PL 3539551T3 PL 19158126 T PL19158126 T PL 19158126T PL 19158126 T PL19158126 T PL 19158126T PL 3539551 T3 PL3539551 T3 PL 3539551T3
- Authority
- PL
- Poland
- Prior art keywords
- related disorders
- receptor related
- heterozygous carriers
- treating melanocortin
- melanocortin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161581391P | 2011-12-29 | 2011-12-29 | |
| EP12863862.4A EP2797615B1 (en) | 2011-12-29 | 2012-12-28 | Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers |
| EP19158126.3A EP3539551B1 (en) | 2011-12-29 | 2012-12-28 | Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers |
| PCT/US2012/072026 WO2013102047A1 (en) | 2011-12-29 | 2012-12-28 | Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3539551T3 true PL3539551T3 (pl) | 2022-02-21 |
Family
ID=48698641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19158126T PL3539551T3 (pl) | 2011-12-29 | 2012-12-28 | Sposób leczenia zaburzeń związanych z receptorem melanokortyny 4 u heterozygotycznych nosicieli |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US9845339B2 (pl) |
| EP (3) | EP3988108A1 (pl) |
| CA (2) | CA3301962A1 (pl) |
| CY (1) | CY1124816T1 (pl) |
| DK (2) | DK3539551T3 (pl) |
| ES (2) | ES2732077T3 (pl) |
| HR (1) | HRP20211950T1 (pl) |
| HU (1) | HUE056948T2 (pl) |
| LT (1) | LT3539551T (pl) |
| PL (1) | PL3539551T3 (pl) |
| PT (2) | PT3539551T (pl) |
| RS (1) | RS62701B1 (pl) |
| SI (1) | SI3539551T1 (pl) |
| SM (1) | SMT202100734T1 (pl) |
| WO (1) | WO2013102047A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3539551T (lt) | 2011-12-29 | 2022-01-10 | Rhythm Pharmaceuticals, Inc. | Su melanokortino-4 receptoriumi susijusių sutrikimų gydymo būdas heterozigotiniuose nešiotojuose |
| PL3356386T3 (pl) * | 2015-09-30 | 2024-08-05 | Rhythm Pharmaceuticals, Inc. | Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4 |
| JP7710707B2 (ja) | 2017-11-15 | 2025-07-22 | リズム ファーマシューティカルズ, インコーポレイテッド | 持続放出ペプチド製剤 |
| US20210169969A1 (en) * | 2018-04-06 | 2021-06-10 | Leonardus H.T. Van Der Ploeg | Compositions for treating kidney disease |
| US11332499B2 (en) | 2018-08-16 | 2022-05-17 | Regents Of The University Of Minnesota | Cyclic peptides and methods of use thereof |
| CN120699097A (zh) * | 2024-09-03 | 2025-09-26 | 万邦德制药集团有限公司 | 一种二硫环肽化合物及其制备方法和应用 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7319107B2 (en) | 2001-11-08 | 2008-01-15 | Johnson & Johnson Consumer Companies, Inc. | 1,2,4-thiadiazolium derivatives as melanocortin receptor modulators |
| FR2851563B1 (fr) | 2003-02-26 | 2005-04-22 | Sod Conseils Rech Applic | Nouveaux derives de benzimidazole et d'imidazo-pyridine et leur utilisation en tant que medicament |
| FR2852957B1 (fr) | 2003-03-31 | 2005-06-10 | Sod Conseils Rech Applic | Nouveaux derives d'imidazo-pyridine et leur utilisation en tant que medicament |
| HUE034290T2 (en) | 2003-04-29 | 2018-02-28 | Orexigen Therapeutics Inc | Preparations containing opioid antagonist and bupropion to affect weight loss |
| US7968548B2 (en) | 2003-05-01 | 2011-06-28 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine compounds with diamine groups |
| EP1644023A2 (en) * | 2003-06-19 | 2006-04-12 | Eli Lilly And Company | Melanocortin recptor 4(mc4) agonists and their uses |
| FR2862971B1 (fr) | 2003-11-28 | 2006-03-24 | Sod Conseils Rech Applic | Nouveaux derives de benzimidazole et d'imidazo-pyridine et leur utilisation en tant que medicament |
| FR2872165B1 (fr) | 2004-06-24 | 2006-09-22 | Sod Conseils Rech Applic | Nouveaux derives de pyrimido-benzimidazole |
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| JP2009500426A (ja) | 2005-07-08 | 2009-01-08 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | メラノコルチン受容体のリガンド |
| NZ565217A (en) | 2005-07-08 | 2010-03-26 | Ipsen Pharma Sas | Melanocortin receptor ligands |
| US8247530B2 (en) | 2005-11-08 | 2012-08-21 | Palatin Technologies, Inc. | N-alkylated cyclic peptide melanocortin agonists |
| US8114844B2 (en) | 2006-03-30 | 2012-02-14 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptidomimetics |
| US8058240B2 (en) * | 2006-04-18 | 2011-11-15 | University Of Florida Research Foundation, Inc. | Biological active ligands of melanocortin receptors |
| US20100016238A1 (en) | 2007-01-18 | 2010-01-21 | Novo Nordisk A/S | Peptides for Use in the Treatment of Obesity |
| US20100056433A1 (en) | 2007-01-18 | 2010-03-04 | Novo Nordisk A/S | Novel Peptides for Use in the Treatment of Obesity |
| WO2008087186A2 (en) | 2007-01-18 | 2008-07-24 | Novo Nordisk A/S | Peptides for use in the treatment of obesity |
| EP2106407A2 (en) | 2007-01-18 | 2009-10-07 | Novo Nordisk A/S | Novel peptides for use in the treatment of obesity |
| EP1974729A1 (en) | 2007-03-28 | 2008-10-01 | Santhera Pharmaceuticals (Schweiz) AG | Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists |
| TWI364290B (en) | 2007-05-25 | 2012-05-21 | Ipsen Pharma Sas | Melanocortin receptor ligands modifled with hydantoin |
| EP2167112A4 (en) * | 2007-06-15 | 2012-01-25 | Ipsen Pharma Sas | CYCLIC PEPTIDE MELANOCORTIN RECEPTOR LIGANDS |
| EP2019100A1 (en) | 2007-07-19 | 2009-01-28 | Santhera Pharmaceuticals (Schweiz) AG | Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators |
| BRPI0819188B1 (pt) * | 2007-11-05 | 2021-06-22 | Ipsen Pharma S.A.S. | Uso de melanocortinas para a preparação de um medicamento para tratar resistência à insulina |
| KR101687037B1 (ko) | 2008-06-09 | 2016-12-15 | 팔라틴 테크놀로지스 인코포레이티드 | 성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드 |
| WO2009151383A1 (en) | 2008-06-09 | 2009-12-17 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides for the treatment of obesity and other diseases associated with melanocortin receptor function |
| KR101280786B1 (ko) | 2008-08-06 | 2013-07-05 | 화이자 리미티드 | 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 |
| US8563742B2 (en) | 2008-08-29 | 2013-10-22 | High Point Pharmaceuticals, Llc | Substituted aminothiazole derivatives, pharmaceutical compositions, and methods of use |
| EP2168965A1 (en) | 2008-09-25 | 2010-03-31 | Santhera Pharmaceuticals (Schweiz) AG | Substituted imidazopyridine, imidazopyrazine, imidazopyridazine and imidazopyrimidine derivatives as melanocortin-4 receptor antagonists |
| WO2010037081A1 (en) | 2008-09-29 | 2010-04-01 | Palatin Technologies, Inc. | Melanocortin receptor-specific spiro-piperidine compounds |
| FR2937868B1 (fr) | 2008-11-04 | 2010-11-05 | Galderma Res & Dev | Composes antagonistes des recepteurs de la melanocortine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| FR2937973B1 (fr) | 2008-11-04 | 2010-11-05 | Galderma Res & Dev | Modulateurs des recepteurs de la melanocortine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| UA99555C2 (en) | 2008-11-12 | 2012-08-27 | Элджи Лайф Саенсез Лтд. | Melanocortin receptor agonists |
| JP2012509862A (ja) | 2008-11-25 | 2012-04-26 | ノヴォ・ノルディスク・アー/エス | 肥満の治療のためのペプチド |
| WO2010065800A1 (en) | 2008-12-04 | 2010-06-10 | Palatin Technologies, Inc. | Hydrazine substituted piperidine melanocortin receptor-specific compounds |
| WO2010065801A1 (en) | 2008-12-04 | 2010-06-10 | Palatin Technologies, Inc. | Amine substituted piperazine melanocortin receptor-specific compounds |
| WO2010065799A2 (en) | 2008-12-04 | 2010-06-10 | Palatin Technologies, Inc. | Amine substituted piperidine melanocortin receptor-specific compounds |
| WO2010065802A2 (en) | 2008-12-04 | 2010-06-10 | Palatin Technologies, Inc. | Substituted pyrrolidine or imidazolidine melanocortin receptor-specific compounds |
| EP2210885A1 (en) | 2009-01-14 | 2010-07-28 | Santhera Pharmaceuticals (Schweiz) AG | Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators |
| WO2010096854A1 (en) | 2009-02-27 | 2010-09-02 | Mimetica Pty Ltd | Methods of modulating the activity of the mc3 and/or mc4 receptors and treatment of conditions related to these receptors |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| EP2440572B1 (en) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Lactam-bridged melanocortin receptor-specific peptides |
| CA2761607C (en) | 2009-06-08 | 2018-09-04 | Yi-Qun Shi | Melanocortin receptor-specific peptides |
| US20120135923A1 (en) * | 2009-08-05 | 2012-05-31 | Ipsen Pharma, S.A.S. | Use of Melanocortins to Treat Dyslipidemia |
| CN102574894A (zh) | 2009-08-31 | 2012-07-11 | 张力控制股份有限公司 | 稳定化的黑皮质素配体 |
| US20120226018A1 (en) | 2009-11-16 | 2012-09-06 | Ipsen Pharma, S.A.S. | Process for the Synthesis of Ac-Arg-Cyclo(Cys-D-Ala-His-D-Phe-Arg-Trp-Cys)-NH2 |
| JP5486690B2 (ja) * | 2009-11-16 | 2014-05-07 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | メラノコルチン受容体リガンドの医薬組成物 |
| US8476227B2 (en) | 2010-01-22 | 2013-07-02 | Ethicon Endo-Surgery, Inc. | Methods of activating a melanocortin-4 receptor pathway in obese subjects |
| EP2539364A1 (en) | 2010-02-26 | 2013-01-02 | Novo Nordisk A/S | Peptides for treatment of obesity |
| BR112012021231A2 (pt) | 2010-02-26 | 2015-09-08 | Basf Plant Science Co Gmbh | método para acentuar o rendimento em plantas, planta, construto, uso de um construto, método para a produção de uma planta transgênica, partes coletáveis de uma planta, produtos derivados de uma planta, uso de um ácido nucleíco e método para a produção de um produto |
| BR112013027222B1 (pt) | 2011-06-14 | 2022-07-12 | Ipsen Pharma S.A.S. | Composição de liberação sustentada que contém peptídeos como ingrediente ativo |
| LT3539551T (lt) | 2011-12-29 | 2022-01-10 | Rhythm Pharmaceuticals, Inc. | Su melanokortino-4 receptoriumi susijusių sutrikimų gydymo būdas heterozigotiniuose nešiotojuose |
| EP2705835A1 (en) | 2012-06-08 | 2014-03-12 | Ipsen Pharma S.A.S. | Aqueous gelling compositions of soluble active pharmaceutical peptides providing modified release |
| CN115957297A (zh) | 2013-03-15 | 2023-04-14 | 节奏制药公司 | 药物组合物 |
| EP2970388B1 (en) | 2013-03-15 | 2018-07-25 | Rhythm Pharmaceuticals, Inc. | Peptide compositions |
| PL3356386T3 (pl) | 2015-09-30 | 2024-08-05 | Rhythm Pharmaceuticals, Inc. | Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4 |
| JP7710707B2 (ja) | 2017-11-15 | 2025-07-22 | リズム ファーマシューティカルズ, インコーポレイテッド | 持続放出ペプチド製剤 |
-
2012
- 2012-12-28 LT LTEP19158126.3T patent/LT3539551T/lt unknown
- 2012-12-28 WO PCT/US2012/072026 patent/WO2013102047A1/en not_active Ceased
- 2012-12-28 SM SM20210734T patent/SMT202100734T1/it unknown
- 2012-12-28 CA CA3301962A patent/CA3301962A1/en active Pending
- 2012-12-28 SI SI201231968T patent/SI3539551T1/sl unknown
- 2012-12-28 PT PT191581263T patent/PT3539551T/pt unknown
- 2012-12-28 US US14/369,116 patent/US9845339B2/en active Active
- 2012-12-28 HR HRP20211950TT patent/HRP20211950T1/hr unknown
- 2012-12-28 PT PT12863862T patent/PT2797615T/pt unknown
- 2012-12-28 EP EP21194299.0A patent/EP3988108A1/en active Pending
- 2012-12-28 EP EP12863862.4A patent/EP2797615B1/en active Active
- 2012-12-28 ES ES12863862T patent/ES2732077T3/es active Active
- 2012-12-28 EP EP19158126.3A patent/EP3539551B1/en active Active
- 2012-12-28 CA CA2862444A patent/CA2862444A1/en active Pending
- 2012-12-28 HU HUE19158126A patent/HUE056948T2/hu unknown
- 2012-12-28 RS RS20211529A patent/RS62701B1/sr unknown
- 2012-12-28 DK DK19158126.3T patent/DK3539551T3/da active
- 2012-12-28 ES ES19158126T patent/ES2897559T3/es active Active
- 2012-12-28 DK DK12863862.4T patent/DK2797615T3/da active
- 2012-12-28 PL PL19158126T patent/PL3539551T3/pl unknown
-
2017
- 2017-10-20 US US15/789,118 patent/US10167312B2/en active Active
-
2019
- 2019-04-15 US US16/383,889 patent/US10954268B2/en active Active
-
2020
- 2020-11-13 US US17/097,122 patent/US11702448B2/en active Active
-
2021
- 2021-12-14 CY CY20211101094T patent/CY1124816T1/el unknown
-
2023
- 2023-06-01 US US18/204,672 patent/US20240190914A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20180194803A1 (en) | 2018-07-12 |
| SI3539551T1 (sl) | 2022-02-28 |
| US11702448B2 (en) | 2023-07-18 |
| WO2013102047A1 (en) | 2013-07-04 |
| EP2797615B1 (en) | 2019-04-03 |
| US9845339B2 (en) | 2017-12-19 |
| CA2862444A1 (en) | 2013-07-04 |
| DK2797615T3 (da) | 2019-07-01 |
| PT3539551T (pt) | 2021-11-04 |
| US20140329743A1 (en) | 2014-11-06 |
| US20200017546A1 (en) | 2020-01-16 |
| LT3539551T (lt) | 2022-01-10 |
| US20210061852A1 (en) | 2021-03-04 |
| DK3539551T3 (da) | 2021-11-01 |
| SMT202100734T1 (it) | 2022-03-21 |
| CA3301962A1 (en) | 2026-03-02 |
| EP3988108A1 (en) | 2022-04-27 |
| HRP20211950T1 (hr) | 2022-03-18 |
| US10167312B2 (en) | 2019-01-01 |
| US10954268B2 (en) | 2021-03-23 |
| CY1124816T1 (el) | 2022-11-25 |
| ES2732077T3 (es) | 2019-11-20 |
| RS62701B1 (sr) | 2022-01-31 |
| EP2797615A1 (en) | 2014-11-05 |
| EP3539551B1 (en) | 2021-10-06 |
| PT2797615T (pt) | 2019-07-11 |
| US20240190914A1 (en) | 2024-06-13 |
| EP3539551A1 (en) | 2019-09-18 |
| EP2797615A4 (en) | 2016-05-18 |
| ES2897559T3 (es) | 2022-03-01 |
| WO2013102047A8 (en) | 2014-02-27 |
| HUE056948T2 (hu) | 2022-04-28 |
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