PL356990A1 - Pochodne izoksazolokarboksyamidu - Google Patents

Pochodne izoksazolokarboksyamidu

Info

Publication number: PL356990A1
Authority: PL; Poland
Prior art keywords: alpha1; receptor antagonists; adrenergic receptor; isoxazolecarboxamide; derivatives
Prior art date: 1999-10-18

Application number

PL00356990A

Other languages

English (en)

Inventor

Amedeo Leonardi

Gianni Motta

Carlo Riva

Elena Poggesi

Original Assignee

Recordati S.A, Chemical And Pharmaceutical Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-18

Filing date

2000-10-16

Publication date

2004-07-12

2000-10-16 Application filed by Recordati S.A, Chemical And Pharmaceutical Company filed Critical Recordati S.A, Chemical And Pharmaceutical Company

2004-07-12 Publication of PL356990A1 publication Critical patent/PL356990A1/pl

Links

LKYNGTHMKCTTQC-UHFFFAOYSA-N 1,2-oxazole-3-carboxamide Chemical class NC(=O)C=1C=CON=1 LKYNGTHMKCTTQC-UHFFFAOYSA-N 0.000 title 1
239000000674 adrenergic antagonist Substances 0.000 title 1
102000030619 alpha-1 Adrenergic Receptor Human genes 0.000 title 1
108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PL00356990A 1999-10-18 2000-10-16 Pochodne izoksazolokarboksyamidu PL356990A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1999MI002173A IT1314191B1 (it)	1999-10-18	1999-10-18	Derivati isossazolcarbossamidici
PCT/EP2000/010144 WO2001029015A2 (en)	1999-10-18	2000-10-16	Isoxazolecarboxamide derivatives as alpha1-adrenergic receptor antagonists

Publications (1)

Publication Number	Publication Date
PL356990A1 true PL356990A1 (pl)	2004-07-12

Family

ID=11383797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00356990A PL356990A1 (pl)	1999-10-18	2000-10-16	Pochodne izoksazolokarboksyamidu

Country Status (25)

Country	Link
EP (1)	EP1226131B1 (pl)
JP (1)	JP2003512362A (pl)
KR (1)	KR20020038944A (pl)
CN (1)	CN1139579C (pl)
AR (1)	AR029400A1 (pl)
AT (1)	ATE256670T1 (pl)
AU (1)	AU757614B2 (pl)
BR (1)	BR0014851A (pl)
CA (1)	CA2385472A1 (pl)
DE (1)	DE60007347T2 (pl)
DK (1)	DK1226131T3 (pl)
ES (1)	ES2210033T3 (pl)
HK (1)	HK1044940A1 (pl)
HU (1)	HUP0203184A3 (pl)
IL (1)	IL148837A0 (pl)
IT (1)	IT1314191B1 (pl)
MX (1)	MXPA02003432A (pl)
MY (1)	MY120400A (pl)
NO (1)	NO20021803L (pl)
NZ (1)	NZ517884A (pl)
PL (1)	PL356990A1 (pl)
PT (1)	PT1226131E (pl)
RU (1)	RU2002113096A (pl)
WO (1)	WO2001029015A2 (pl)
ZA (1)	ZA200203942B (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101277952B (zh)	2005-10-11	2011-09-28	弗·哈夫曼-拉罗切有限公司	异*唑衍生物
DE602006014185D1 (de)	2005-11-09	2010-06-17	Hoffmann La Roche	3-arylisoxazol-4-carbonylbenzofuranderivative
RU2426731C2 (ru)	2005-12-23	2011-08-20	Ф. Хоффманн-Ля Рош Аг	Производные арил-изоксазоло-4-ил-оксадиазола
PL1968973T3 (pl)	2005-12-27	2012-03-30	Hoffmann La Roche	Pochodne aryloizoksazol-4-iloimidazolu
KR101062583B1 (ko)	2006-01-17	2011-09-06	에프. 호프만-라 로슈 아게	Ｇａｂａ 수용체에 의해 알츠하이머병의 치료에 유용한아릴-아이속사졸-4-일-이미다조[1,2-ａ]피리딘
KR101119365B1 (ko)	2006-05-31	2012-03-07	에프. 호프만-라 로슈 아게	아릴-4-에틴일-아이속사졸 유도체
CN101965344B (zh)	2007-06-22	2013-03-06	弗·哈夫曼-拉罗切有限公司	异*唑-咪唑衍生物
US7902201B2 (en)	2007-12-04	2011-03-08	Hoffmann-La Roche Inc.	Isoxazolo-pyrazine derivatives
US7943619B2 (en)	2007-12-04	2011-05-17	Hoffmann-La Roche Inc.	Isoxazolo-pyridazine derivatives
US7618973B2 (en)	2007-12-04	2009-11-17	Hoffmann-La Roche Inc.	Isoxazolo-pyrazine derivatives
WO2010081851A1 (en)	2009-01-14	2010-07-22	Genoscience Pharma	Piperidin-4-ylpiperazine compounds for the treatment of hcv infection
TW201033201A (en)	2009-02-19	2010-09-16	Hoffmann La Roche	Isoxazole-isoxazole and isoxazole-isothiazole derivatives
US8389550B2 (en)	2009-02-25	2013-03-05	Hoffmann-La Roche Inc.	Isoxazoles / O-pyridines with ethyl and ethenyl linker
US8222246B2 (en)	2009-04-02	2012-07-17	Hoffmann-La Roche Inc.	Substituted isoxazoles
US8227461B2 (en)	2009-04-30	2012-07-24	Hoffmann-La Roche Inc.	Isoxazoles
ES2601181T3 (es)	2009-05-05	2017-02-14	F. Hoffmann-La Roche Ag	Derivados de isoxazol-tiazol como agonistas inversos del receptor GABA A para su uso en el tratamiento de trastornos cognitivos
BRPI1014454A2 (pt)	2009-05-05	2016-04-05	Hoffmann La Roche	derivados de isoxazol-pirazol
BRPI1013762A2 (pt)	2009-05-05	2015-08-25	Hoffmann La Roche	"derivados isoxazol-piridazina"
US8415379B2 (en)	2009-05-05	2013-04-09	Hoffmann-La Roche Inc.	Pyridines
KR101354416B1 (ko)	2009-05-07	2014-02-19	에프. 호프만-라 로슈 아게	감마-아미노부티르산 조절제로서 이속사졸-피리딘 유도체
US8785435B2 (en)	2011-10-20	2014-07-22	Hoffmann-La Roche Inc.	Solid forms
CN113121540B (zh) *	2020-01-15	2024-01-26	鲁南制药集团股份有限公司	一种西格列汀游离碱的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1254469B (it) *	1992-02-25	1995-09-25	Recordati Chem Pharm	Derivati benzopiranici e benzotiopiranici
IT1266582B1 (it) *	1993-07-30	1997-01-09	Recordati Chem Pharm	Derivati (di)azacicloesanici e diazacicloeptanici
DE4425146A1 (de) *	1994-07-15	1996-01-18	Basf Ag	Verwendung heterocyclischer Verbindungen

1999
- 1999-10-18 IT IT1999MI002173A patent/IT1314191B1/it active
2000
- 2000-10-10 MY MYPI20004718A patent/MY120400A/en unknown
- 2000-10-16 ES ES00992436T patent/ES2210033T3/es not_active Expired - Lifetime
- 2000-10-16 BR BR0014851-2A patent/BR0014851A/pt not_active IP Right Cessation
- 2000-10-16 CN CNB008143226A patent/CN1139579C/zh not_active Expired - Fee Related
- 2000-10-16 RU RU2002113096/04A patent/RU2002113096A/ru not_active Application Discontinuation
- 2000-10-16 DK DK00992436T patent/DK1226131T3/da active
- 2000-10-16 PT PT00992436T patent/PT1226131E/pt unknown
- 2000-10-16 NZ NZ517884A patent/NZ517884A/en unknown
- 2000-10-16 AT AT00992436T patent/ATE256670T1/de not_active IP Right Cessation
- 2000-10-16 WO PCT/EP2000/010144 patent/WO2001029015A2/en not_active Ceased
- 2000-10-16 HK HK02105918.6A patent/HK1044940A1/zh unknown
- 2000-10-16 IL IL14883700A patent/IL148837A0/xx unknown
- 2000-10-16 AU AU28347/01A patent/AU757614B2/en not_active Ceased
- 2000-10-16 CA CA002385472A patent/CA2385472A1/en not_active Abandoned
- 2000-10-16 EP EP00992436A patent/EP1226131B1/en not_active Expired - Lifetime
- 2000-10-16 DE DE60007347T patent/DE60007347T2/de not_active Expired - Fee Related
- 2000-10-16 JP JP2001531815A patent/JP2003512362A/ja active Pending
- 2000-10-16 MX MXPA02003432A patent/MXPA02003432A/es not_active Application Discontinuation
- 2000-10-16 PL PL00356990A patent/PL356990A1/pl not_active Application Discontinuation
- 2000-10-16 KR KR1020027004663A patent/KR20020038944A/ko not_active Withdrawn
- 2000-10-16 HU HU0203184A patent/HUP0203184A3/hu unknown
- 2000-10-18 AR ARP000105475A patent/AR029400A1/es not_active Application Discontinuation
2002
- 2002-04-17 NO NO20021803A patent/NO20021803L/no not_active Application Discontinuation
- 2002-05-17 ZA ZA200203942A patent/ZA200203942B/en unknown

Also Published As

Publication number	Publication date
IL148837A0 (en)	2002-09-12
DE60007347T2 (de)	2004-09-02
NO20021803D0 (no)	2002-04-17
BR0014851A (pt)	2002-06-11
ES2210033T3 (es)	2004-07-01
WO2001029015A3 (en)	2001-11-01
EP1226131B1 (en)	2003-12-17
IT1314191B1 (it)	2002-12-06
ITMI992173A1 (it)	2001-04-18
HK1044940A1 (zh)	2002-11-08
DE60007347D1 (de)	2004-01-29
DK1226131T3 (da)	2004-04-19
ATE256670T1 (de)	2004-01-15
PT1226131E (pt)	2004-05-31
WO2001029015A2 (en)	2001-04-26
EP1226131A2 (en)	2002-07-31
ITMI992173A0 (it)	1999-10-18
CN1379767A (zh)	2002-11-13
NZ517884A (en)	2003-08-29
MXPA02003432A (es)	2002-08-20
ZA200203942B (en)	2003-01-02
MY120400A (en)	2005-10-31
HUP0203184A3 (en)	2004-12-28
HUP0203184A2 (hu)	2003-01-28
CA2385472A1 (en)	2001-04-26
JP2003512362A (ja)	2003-04-02
RU2002113096A (ru)	2003-11-10
KR20020038944A (ko)	2002-05-24
AR029400A1 (es)	2003-06-25
AU757614B2 (en)	2003-02-27
CN1139579C (zh)	2004-02-25
NO20021803L (no)	2002-06-17
AU2834701A (en)	2001-04-30

Legal Events

Date	Code	Title	Description
2008-08-29	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
IL154079A0 (en)	2003-07-31	4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists
PL357433A1 (pl)	2004-07-26	Pochodne benzodiazepiny
PL357418A1 (pl)	2004-07-26	Pochodne benzodiazepiny
EP1206262A4 (en)	2003-01-02	Y NEUROPEPTID ANTAGONISTS: SPIROISOQUINOLINONE DERIVATIVES
EP1224173A4 (en)	2002-11-20	PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS
HRP20030031A2 (en)	2004-02-29	4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists
IL148058A0 (en)	2002-09-12	Substituted 2-dialkylaminoalkylbiphenyl derivatives
HUP0201524A3 (en)	2005-05-30	Bradykinin receptor antagonists
IL148623A0 (en)	2002-09-12	Thienoisoxazolyl-and thienylpyrazolyl-phenoxy substituted propyl derivatives useful as d4 antagonists
EP1248607A4 (en)	2004-10-06	UROTENSIN II RECEPTOR ANTAGONISTS
IL146151A0 (en)	2002-07-25	Human-g-protein receptor
PL350536A1 (en)	2002-12-16	Biphenyl derivatives as antagonists of the neurokinine-1 receptor
IL144299A0 (en)	2002-05-23	N-triazolymethyl-piperazine derivatives as neurokinin receptor antagonists
IL148043A0 (en)	2002-09-12	Novel integrin receptor antagonists
AU1100300A (en)	2000-04-26	Piperidyloxadiazoles as dopamine receptor antagonists
IL146146A0 (en)	2002-07-25	Integrin receptor antagonists
IL150272A0 (en)	2002-12-01	Indole derivatives as mcp-1 receptor antagonists
EG24179A (en)	2008-09-28	Vitronectin receptor antagonists
AU2574801A (en)	2001-07-03	Selective iGLUR5 receptor antagonists
AU2943899A (en)	1999-10-11	Indole derivatives as 5-ht2a receptor antagonists
GB0026327D0 (en)	2000-12-13	Thrombin receptor antagonists
AU5572500A (en)	2001-01-22	Vegf receptor antagonists
AU5168900A (en)	2000-12-18	Il-8 receptor antagonists
AU2512800A (en)	2000-08-25	Alpha1-adrenergic receptor antagonists
GB9923910D0 (en)	1999-12-08	Prolactin receptor