PL357557A1 - Kompleks klatratowy utworzony z pochodnych kwasu hialuronowego, sposób jego otrzymywania oraz farmaceutyczne kompozycje i ich stosowanie - Google Patents

Kompleks klatratowy utworzony z pochodnych kwasu hialuronowego, sposób jego otrzymywania oraz farmaceutyczne kompozycje i ich stosowanie

Info

Publication number
PL357557A1
PL357557A1 PL01357557A PL35755701A PL357557A1 PL 357557 A1 PL357557 A1 PL 357557A1 PL 01357557 A PL01357557 A PL 01357557A PL 35755701 A PL35755701 A PL 35755701A PL 357557 A1 PL357557 A1 PL 357557A1
Authority
PL
Poland
Prior art keywords
pharmaceuticals
hyaluronic acid
acid derivatives
complexes formed
clathrate complexes
Prior art date
Application number
PL01357557A
Other languages
English (en)
Other versions
PL204330B1 (pl
Inventor
Ladislav Soltes
Bohumil Steiner
Eva Machova
Grigorij Kogan
Slavomir Bystricky
Raniero Mendichi
Viktor Bauer
Mojmir Mach
Juraj Alfoldi
Eva Stratilova
Original Assignee
Fidia Farmaceutici S.P.A.
Slovak Academy Of Sciences Institute Of Experimental Pharmacology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici S.P.A., Slovak Academy Of Sciences Institute Of Experimental Pharmacology filed Critical Fidia Farmaceutici S.P.A.
Publication of PL357557A1 publication Critical patent/PL357557A1/pl
Publication of PL204330B1 publication Critical patent/PL204330B1/pl

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL357557A 2000-03-10 2001-03-12 Kompleks klatratowy utworzony z pochodnych kwasu hialuronowego, sposób jego otrzymywania, kompozycje farmaceutyczne, ich zastosowania oraz zastosowania pochodnych kwasu hialuronowego PL204330B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK358-2000A SK282717B6 (sk) 2000-03-10 2000-03-10 Spôsob prípravy ultravysokomolekulových hyalurónanov
PCT/EP2001/002722 WO2001066601A1 (en) 2000-03-10 2001-03-12 Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals

Publications (2)

Publication Number Publication Date
PL357557A1 true PL357557A1 (pl) 2004-07-26
PL204330B1 PL204330B1 (pl) 2010-01-29

Family

ID=20435814

Family Applications (1)

Application Number Title Priority Date Filing Date
PL357557A PL204330B1 (pl) 2000-03-10 2001-03-12 Kompleks klatratowy utworzony z pochodnych kwasu hialuronowego, sposób jego otrzymywania, kompozycje farmaceutyczne, ich zastosowania oraz zastosowania pochodnych kwasu hialuronowego

Country Status (13)

Country Link
US (1) US7563824B2 (pl)
EP (1) EP1272530B1 (pl)
JP (1) JP2003525980A (pl)
AU (2) AU2001252180B2 (pl)
CA (1) CA2402421C (pl)
CZ (1) CZ20023029A3 (pl)
DE (1) DE60123225T2 (pl)
ES (1) ES2272465T3 (pl)
HU (1) HUP0300163A3 (pl)
NO (1) NO330340B1 (pl)
PL (1) PL204330B1 (pl)
SK (1) SK282717B6 (pl)
WO (1) WO2001066601A1 (pl)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI321054B (en) 2000-12-19 2010-03-01 California Inst Of Techn Compositions containing inclusion complexes
JP2004018750A (ja) * 2002-06-18 2004-01-22 Seikagaku Kogyo Co Ltd 親水性を向上したヒアルロン酸誘導体の製造方法
ES2377318T3 (es) 2002-09-06 2012-03-26 Cerulean Pharma Inc. Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
KR20050051686A (ko) 2002-10-09 2005-06-01 인설트 테라페틱스, 인코퍼레이티드 사이클로덱스트린-기초한 재료, 조성물 및 이의 용도
WO2004060404A1 (ja) * 2002-12-27 2004-07-22 Chugai Seiyaku Kabushiki Kaisha 薬物担体
US20050147584A1 (en) * 2004-01-05 2005-07-07 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
US20050031652A1 (en) * 2003-02-25 2005-02-10 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
EP1884231A1 (en) * 2006-08-01 2008-02-06 Auriga International S.A. Cosmetic or pharmaceutical composition containing hyaluronic acid
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
US8966080B2 (en) * 2007-04-13 2015-02-24 Emc Corporation Systems and methods of managing resource utilization on a threaded computer system
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
US8211450B2 (en) 2010-05-05 2012-07-03 Senju Usa, Inc. Ophthalmic composition
PH12013500477A1 (en) 2010-09-13 2018-01-17 Bev Rx Inc Aqueous drug delivery system comprising off-flavor masking agent
US9590913B2 (en) 2011-02-07 2017-03-07 LiveQoS Inc. System and method for reducing bandwidth usage of a network
KR101383941B1 (ko) * 2012-03-09 2014-04-10 동아에스티 주식회사 피록시캄 또는 약제학적으로 허용되는 그의 염과 히알루론산 또는 약제학적으로 허용되는 그의 염의 안정한 액상 조성물 및 그 제조방법
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
US20160129134A1 (en) * 2013-06-14 2016-05-12 Galderma S.A. Compositions comprising cross-linked hyaluronic acid and cyclodextrin
ITMI20132116A1 (it) * 2013-12-18 2015-06-19 Apharm Srl Associazione di glicosamminoglicani e ciclodestrine
CN105153481B (zh) * 2015-10-16 2017-06-16 南开大学 一种荧光超分子纳米粒子及其制备方法和应用
EP3475312B1 (en) 2016-06-23 2020-05-27 Galderma S.A. Cyclodextrin-grafted cross-linked hyaluronic acid complexed with active drug substances and uses thereof
CN106491526B (zh) * 2016-11-14 2019-03-22 暨南大学 一种药物缓释型复合滴眼液及其制备方法与应用
CN106759942B (zh) * 2017-03-01 2022-07-01 邓剑涛 一种一体固化的无焊接销锁连接结构及其施工方法
IT201800007683A1 (it) 2018-07-31 2020-01-31 Altergon Sa Composizioni cooperative sinergiche utili per aumento del tessuto molle, rilascio di farmaco e campi correlati
IT201800009444A1 (it) * 2018-10-15 2020-04-15 Fidia Farm Spa Coniugati tra acido ialuronico e amminobisfosfonati e loro impiego terapeutico
EP4072590A4 (en) * 2019-12-13 2024-01-03 Folium Labs Inc. COMPLEXES COMPRISING A CARBOHYDRATE POLYMER AND AN ACTIVE INGREDIENT AND THEIR PREPARATION PROCESSES
CN116806818B (zh) * 2023-05-19 2025-08-29 内蒙古农业大学 超分子杂化水凝胶及其制备方法、农药及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309669B1 (en) * 1984-03-16 2001-10-30 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
US4636524A (en) * 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5470512A (en) * 1990-05-24 1995-11-28 Nippon Kayaku Kabushiki Kaisha Process for producing microcapsules
FR2665158B1 (fr) * 1990-07-30 1993-12-24 Air Liquide Clathrates de peroxyacides.
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses

Also Published As

Publication number Publication date
WO2001066601A8 (en) 2002-01-03
EP1272530A1 (en) 2003-01-08
JP2003525980A (ja) 2003-09-02
HUP0300163A2 (hu) 2003-06-28
NO20024192L (no) 2002-09-03
AU2001252180B2 (en) 2005-06-30
SK282717B6 (sk) 2002-11-06
ES2272465T3 (es) 2007-05-01
DE60123225D1 (de) 2006-11-02
CA2402421A1 (en) 2001-09-13
NO20024192D0 (no) 2002-09-03
US7563824B2 (en) 2009-07-21
DE60123225T2 (de) 2007-09-20
HUP0300163A3 (en) 2003-09-29
NO330340B1 (no) 2011-03-28
CA2402421C (en) 2009-12-22
WO2001066601A1 (en) 2001-09-13
US20040076680A1 (en) 2004-04-22
PL204330B1 (pl) 2010-01-29
SK3582000A3 (en) 2002-09-10
AU5218001A (en) 2001-09-17
EP1272530B1 (en) 2006-09-20
CZ20023029A3 (cs) 2003-04-16

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20130312