PL358333A1 - Nitroiloksylowe pochodne (R) i (S)-karnityny - Google Patents

Nitroiloksylowe pochodne (R) i (S)-karnityny

Info

Publication number
PL358333A1
PL358333A1 PL00358333A PL35833300A PL358333A1 PL 358333 A1 PL358333 A1 PL 358333A1 PL 00358333 A PL00358333 A PL 00358333A PL 35833300 A PL35833300 A PL 35833300A PL 358333 A1 PL358333 A1 PL 358333A1
Authority
PL
Poland
Prior art keywords
carnitine
derivatives
formula
nitroxy derivatives
nitroxy
Prior art date
Application number
PL00358333A
Other languages
English (en)
Other versions
PL203519B1 (pl
Inventor
Oreste Piccolo
Roberto Castagnani
Witt Paolo De
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of PL358333A1 publication Critical patent/PL358333A1/pl
Publication of PL203519B1 publication Critical patent/PL203519B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL358333A 1999-08-05 2000-07-31 Sposób wytwarzania (R) i (S)-karnityny oraz zastosowanie zwi azku nitrooksylowego i pochodnej laktonu jako zwi azków po srednich PL203519B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999RM000508A IT1306184B1 (it) 1999-08-05 1999-08-05 Nitrilossi derivati della (r) e (s)-carnitina.
ITRM99A000508 1999-08-05

Publications (2)

Publication Number Publication Date
PL358333A1 true PL358333A1 (pl) 2004-08-09
PL203519B1 PL203519B1 (pl) 2009-10-30

Family

ID=

Also Published As

Publication number Publication date
KR20020025213A (ko) 2002-04-03
US20020119965A1 (en) 2002-08-29
ES2226896T3 (es) 2005-04-01
KR100772205B1 (ko) 2007-11-01
SK1752002A3 (en) 2002-06-04
ITRM990508A0 (it) 1999-08-05
ITRM990508A1 (it) 2001-02-05
ATE276231T1 (de) 2004-10-15
DK1224161T3 (da) 2005-01-24
HUP0203034A3 (en) 2003-11-28
DE60013876D1 (de) 2004-10-21
JP2003506429A (ja) 2003-02-18
HUP0203034A2 (hu) 2003-02-28
US20010011074A1 (en) 2001-08-02
SK287134B6 (sk) 2010-01-07
IT1306184B1 (it) 2001-05-30
WO2001010819A1 (en) 2001-02-15
US6395923B2 (en) 2002-05-28
PT1224161E (pt) 2005-01-31
EP1224161B1 (en) 2004-09-15
US6548693B2 (en) 2003-04-15
DE60013876T2 (de) 2005-09-29
AU6470400A (en) 2001-03-05
CA2379047A1 (en) 2001-02-15
EP1224161A1 (en) 2002-07-24
CZ20025A3 (cs) 2002-07-17

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