PL360669A1 - 4-Fluorowcowane 17-metylenosteroidy, sposób ich wytwarzania i kompozycje farmaceutyczne zawierającete związki - Google Patents

4-Fluorowcowane 17-metylenosteroidy, sposób ich wytwarzania i kompozycje farmaceutyczne zawierającete związki

Info

Publication number: PL360669A1
Authority: PL; Poland
Prior art keywords: compounds; production; pharmaceutical compositions; compositions containing; halogenated
Prior art date: 2000-09-04

Application number

PL36066901A

Other languages

English (en)

Inventor

Bernd Menzenbach

Walter Elger

Peter Droescher

Alexander Hillisch

Günter Kaufmann

Hans-Udo Schweikert

Gerd Müller

Original Assignee

Jenapharm Gmbh & Co.Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-04

Filing date

2001-08-29

Publication date

2004-09-20

2001-08-29 Application filed by Jenapharm Gmbh & Co.Kg filed Critical Jenapharm Gmbh & Co.Kg

2004-09-20 Publication of PL360669A1 publication Critical patent/PL360669A1/pl

Links

150000001875 compounds Chemical class 0.000 title abstract 5
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
239000003098 androgen Substances 0.000 abstract 2
108010066551 Cholestenone 5 alpha-Reductase Proteins 0.000 abstract 1
229940124558 contraceptive agent Drugs 0.000 abstract 1
239000003433 contraceptive agent Substances 0.000 abstract 1
239000000262 estrogen Substances 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
230000003054 hormonal effect Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
239000000583 progesterone congener Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
229960003604 testosterone Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL36066901A 2000-09-04 2001-08-29 4-Fluorowcowane 17-metylenosteroidy, sposób ich wytwarzania i kompozycje farmaceutyczne zawierającete związki PL360669A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10043846A DE10043846A1 (de)	2000-09-04	2000-09-04	17-Methylensteroide, Verfahren zu deren Herstellung und diese Verbindung enthaltende pharmazeutische Zusammensetzungen
PCT/EP2001/009943 WO2002019971A1 (de)	2000-09-04	2001-08-29	4-halogenierte 17-methylensteroide, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen

Publications (1)

Publication Number	Publication Date
PL360669A1 true PL360669A1 (pl)	2004-09-20

Family

ID=7655148

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL36066901A PL360669A1 (pl)	2000-09-04	2001-08-29	4-Fluorowcowane 17-metylenosteroidy, sposób ich wytwarzania i kompozycje farmaceutyczne zawierającete związki

Country Status (28)

Country	Link
EP (1)	EP1423407B1 (pl)
JP (1)	JP2004513084A (pl)
KR (1)	KR100530816B1 (pl)
CN (1)	CN1262560C (pl)
AT (1)	ATE319733T1 (pl)
AU (2)	AU1047002A (pl)
BG (1)	BG107594A (pl)
BR (1)	BR0113618A (pl)
CA (1)	CA2421302C (pl)
DE (2)	DE10043846A1 (pl)
DK (1)	DK1423407T3 (pl)
EA (1)	EA006387B1 (pl)
EE (1)	EE05186B1 (pl)
ES (1)	ES2260294T3 (pl)
HR (1)	HRP20030256A2 (pl)
HU (1)	HUP0300936A3 (pl)
IL (2)	IL154666A0 (pl)
ME (1)	MEP14408A (pl)
MX (1)	MXPA03001912A (pl)
NO (1)	NO325012B1 (pl)
NZ (1)	NZ524485A (pl)
PL (1)	PL360669A1 (pl)
PT (1)	PT1423407E (pl)
RS (1)	RS50305B (pl)
SK (1)	SK286757B6 (pl)
UA (1)	UA74592C2 (pl)
WO (1)	WO2002019971A1 (pl)
ZA (1)	ZA200301715B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10141984A1 (de)	2001-08-28	2003-03-20	Jenapharm Gmbh	Neue 17-Methylen-4-azasteroide
US7199115B2 (en)	2004-04-19	2007-04-03	Schering Ag	17α-fluorosteroids, pharmaceutical compositions containing 17α-fluorosteroids and a method of making them
AT12800U1 (de) *	2007-11-05	2012-11-15	Bayer Schering Pharma Ag	Pharmazeutisches Präparat zur Verwendung bei der oralen Kontrazeption von Frauen mit Laktoseintoleranz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2611773A (en) *	1951-08-21	1952-09-23	Upjohn Co	Estradiol 17-cyclopenetanepropionate
US3146239A (en) *	1957-09-23	1964-08-25	Syntex Corp	4-halo-19-nor-progesterone
US3232960A (en) *	1959-10-08	1966-02-01	Upjohn Co	3-keto-4-fluoro- and 3-keto-4,4-difluorosteroids and process
US3661940A (en) *	1970-04-13	1972-05-09	Sandoz Ag	Derivatives of 21-methyl-19-norpregnanes
US4389345A (en) *	1981-10-09	1983-06-21	G.D. Searle & Co.	3-Oxoestra-17-acetonitrile and unsaturated analogs
US5994334A (en) *	1997-02-05	1999-11-30	University Of Maryland	Androgen synthesis inhibitors
AU2001268661A1 (en) *	2000-06-27	2002-01-08	Aventis Pharma S.A.	20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase

2000
- 2000-09-04 DE DE10043846A patent/DE10043846A1/de not_active Ceased
2001
- 2001-08-29 NZ NZ524485A patent/NZ524485A/en unknown
- 2001-08-29 AU AU1047002A patent/AU1047002A/xx active Pending
- 2001-08-29 IL IL15466601A patent/IL154666A0/xx unknown
- 2001-08-29 EA EA200300322A patent/EA006387B1/ru not_active IP Right Cessation
- 2001-08-29 SK SK244-2003A patent/SK286757B6/sk not_active IP Right Cessation
- 2001-08-29 WO PCT/EP2001/009943 patent/WO2002019971A1/de not_active Ceased
- 2001-08-29 KR KR10-2003-7003170A patent/KR100530816B1/ko not_active Expired - Fee Related
- 2001-08-29 BR BR0113618-6A patent/BR0113618A/pt not_active IP Right Cessation
- 2001-08-29 PL PL36066901A patent/PL360669A1/pl unknown
- 2001-08-29 EE EEP200300087A patent/EE05186B1/xx not_active IP Right Cessation
- 2001-08-29 HR HR20030256A patent/HRP20030256A2/hr not_active Application Discontinuation
- 2001-08-29 EP EP01978315A patent/EP1423407B1/de not_active Expired - Lifetime
- 2001-08-29 UA UA2003042852A patent/UA74592C2/uk unknown
- 2001-08-29 AU AU2002210470A patent/AU2002210470B2/en not_active Ceased
- 2001-08-29 CA CA002421302A patent/CA2421302C/en not_active Expired - Fee Related
- 2001-08-29 ME MEP-144/08A patent/MEP14408A/xx unknown
- 2001-08-29 AT AT01978315T patent/ATE319733T1/de not_active IP Right Cessation
- 2001-08-29 DE DE50109175T patent/DE50109175D1/de not_active Expired - Lifetime
- 2001-08-29 MX MXPA03001912A patent/MXPA03001912A/es active IP Right Grant
- 2001-08-29 HU HU0300936A patent/HUP0300936A3/hu unknown
- 2001-08-29 PT PT01978315T patent/PT1423407E/pt unknown
- 2001-08-29 DK DK01978315T patent/DK1423407T3/da active
- 2001-08-29 RS YUP-164/03A patent/RS50305B/sr unknown
- 2001-08-29 JP JP2002524456A patent/JP2004513084A/ja active Pending
- 2001-08-29 ES ES01978315T patent/ES2260294T3/es not_active Expired - Lifetime
- 2001-08-29 CN CNB018151345A patent/CN1262560C/zh not_active Expired - Fee Related
2003
- 2003-02-27 BG BG107594A patent/BG107594A/bg unknown
- 2003-02-27 IL IL154666A patent/IL154666A/en not_active IP Right Cessation
- 2003-02-28 ZA ZA200301715A patent/ZA200301715B/en unknown
- 2003-03-03 NO NO20030989A patent/NO325012B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT1423407E (pt)	2006-07-31
IL154666A0 (en)	2003-09-17
EP1423407A1 (de)	2004-06-02
ZA200301715B (en)	2004-08-13
NZ524485A (en)	2005-11-25
EE05186B1 (et)	2009-06-15
SK2442003A3 (en)	2003-08-05
WO2002019971A1 (de)	2002-03-14
EA006387B1 (ru)	2005-12-29
UA74592C2 (en)	2006-01-16
CA2421302C (en)	2007-08-14
ATE319733T1 (de)	2006-03-15
NO20030989L (no)	2003-05-02
MXPA03001912A (es)	2004-07-08
BR0113618A (pt)	2003-07-15
BG107594A (bg)	2003-09-30
YU16403A (sh)	2006-05-25
DK1423407T3 (da)	2006-07-03
CN1262560C (zh)	2006-07-05
EP1423407B1 (de)	2006-03-08
JP2004513084A (ja)	2004-04-30
AU2002210470B2 (en)	2006-07-20
KR100530816B1 (ko)	2005-11-25
HRP20030256A2 (en)	2005-10-31
RS50305B (sr)	2009-09-08
KR20030028836A (ko)	2003-04-10
NO325012B1 (no)	2008-01-14
DE10043846A1 (de)	2002-04-04
HUP0300936A2 (hu)	2003-11-28
HK1060135A1 (en)	2004-07-30
EA200300322A1 (ru)	2003-10-30
CN1452628A (zh)	2003-10-29
IL154666A (en)	2008-12-29
SK286757B6 (sk)	2009-05-07
NO20030989D0 (no)	2003-03-03
MEP14408A (en)	2010-06-10
ES2260294T3 (es)	2006-11-01
EE200300087A (et)	2005-02-15
CA2421302A1 (en)	2003-03-03
DE50109175D1 (de)	2006-05-04
HUP0300936A3 (en)	2010-01-28
WO2002019971A9 (de)	2002-08-08
AU1047002A (en)	2002-03-22

Legal Events

Date	Code	Title	Description
2010-12-31	DISC	Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
UA66861C2 (uk)	2004-06-15	2-феніл-1-[4-(2-аміноетокси)бензил]індол в комбінації з естрогенами, способи лікування та продукт для лікування
ZA200203439B (en)	2003-08-18	Novel tropical oestroprogestational compositions with systemic effect.
PL380866A1 (pl)	2001-08-13	Zastosowanie smilageniny do leczenia choroby Parkinsona
AU1941802A (en)	2002-07-01	Compositions of estrogen-cyclodextrin complexes
DE59510887D1 (de)	2004-05-13	Feste arzneiformen, enthaltend clathrate vom steroidalen sexualhormon ethinylestradiol
DE60115274D1 (de)	2005-12-29	Verwendung von antiprogestinen zur prophylaxe und behandlung von hormonabhängigen erkrankungen
WO2002019982A3 (en)	2003-07-24	Cosmetic composition and method for reducing or preventing wrinkling
WO2005077968A3 (en)	2006-08-31	17-methylene-or 17 - spiro - cyclopropane 7 - substituted estra - 1, 3, 5 (10) - triene derivatives with anti - estrogenic activity
IL125821A0 (en)	1999-04-11	A pharmaceutical composition containing dehydroepiandrosterone and aromatase inhibitors and use thereof
IL154666A0 (en)	2003-09-17	17-methylene steroids, method for the production thereof and pharmaceutical compositions containing these compounds
BG103060A (bg)	1999-10-29	19- нор- холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса причовек
MXPA05008347A (es)	2005-11-04	Composicion que comprende una combinacion de un inhibidor de aromatasa, una progestina y un estrogeno y su uso para el tratamiento de endometriosis.
HUP0101005A2 (hu)	2001-08-28	Szteroid aromatáz gátlót tartalmazó gyógyszer emlőrák megelőzésére és/vagy kezelésére
WO2002020000A3 (en)	2003-02-27	Combined estrogen blockade of the breast with exemestane and raloxifene
UA85190C2 (en)	2009-01-12	PROCESS FOR THE SYNTHESIS OF PURE D-(17α)-13-ETHYL-17-HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE-3E- AND -3Z-OXIME ISOMERS AND THE MIXTURE OF ISOMERS, AND USE OF THOSE ISOMERS
AR048829A1 (es)	2006-05-31	17alfa - fluoroesteroides con actividad inhibidora de 5 alfa-reductasa; composiciones farmaceuticas que los contienen y su uso en la preparacion de medicamentos para el tratamiento de enfermedades cancerosas influidas por androgenos.