PL3613739T3 - Antagoniści integryn - Google Patents
Antagoniści integrynInfo
- Publication number
- PL3613739T3 PL3613739T3 PL19192402.6T PL19192402T PL3613739T3 PL 3613739 T3 PL3613739 T3 PL 3613739T3 PL 19192402 T PL19192402 T PL 19192402T PL 3613739 T3 PL3613739 T3 PL 3613739T3
- Authority
- PL
- Poland
- Prior art keywords
- integrin antagonists
- integrin
- antagonists
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- 102000006495 integrins Human genes 0.000 title 1
- 108010044426 integrins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18189615 | 2018-08-17 | ||
| EP18194258 | 2018-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3613739T3 true PL3613739T3 (pl) | 2021-03-22 |
Family
ID=67659335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19192402.6T PL3613739T3 (pl) | 2018-08-17 | 2019-08-19 | Antagoniści integryn |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US10703752B2 (pl) |
| EP (2) | EP3837257A1 (pl) |
| JP (1) | JP7083073B2 (pl) |
| KR (1) | KR20210057735A (pl) |
| CN (1) | CN112805284A (pl) |
| AU (1) | AU2019326932A1 (pl) |
| BR (1) | BR112021002839A2 (pl) |
| CA (1) | CA3109326A1 (pl) |
| CO (1) | CO2021002395A2 (pl) |
| CY (1) | CY1123871T1 (pl) |
| DK (1) | DK3613739T3 (pl) |
| ES (1) | ES2836733T3 (pl) |
| HU (1) | HUE051802T2 (pl) |
| IL (1) | IL280857A (pl) |
| LT (1) | LT3613739T (pl) |
| MA (1) | MA53218A (pl) |
| MX (1) | MX2021001786A (pl) |
| PL (1) | PL3613739T3 (pl) |
| RS (1) | RS61182B1 (pl) |
| SG (1) | SG11202101424XA (pl) |
| SI (1) | SI3613739T1 (pl) |
| SM (1) | SMT202000623T1 (pl) |
| WO (1) | WO2020043533A1 (pl) |
| ZA (1) | ZA202101406B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3873884T3 (fi) | 2018-10-30 | 2025-02-24 | Gilead Sciences Inc | 3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa |
| JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ， インコーポレイテッド | アルファ４ベータ７インテグリンの阻害のための化合物 |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| EP3873605B1 (en) | 2018-10-30 | 2024-10-23 | Gilead Sciences, Inc. | Compounds for inhibition of alpha4beta7 integrin |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| WO2023001288A1 (zh) * | 2021-07-23 | 2023-01-26 | 百奥泰生物制药股份有限公司 | 整合素GPIIb/IIIa拮抗剂及其和抗VEGF抗体联合用药的应用 |
| CN118356501A (zh) * | 2023-01-19 | 2024-07-19 | 百奥泰生物制药股份有限公司 | 一种复方制剂及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2847254B1 (fr) | 2002-11-19 | 2005-01-28 | Aventis Pharma Sa | Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant |
| FR2870541B1 (fr) * | 2004-05-18 | 2006-07-14 | Proskelia Sas | Derives de pyrimidines antigonistes du recepteur de la vitronectine |
| US20110189174A1 (en) | 2010-02-01 | 2011-08-04 | Afshin Shafiee | Compositions and methods for treating, reducing, ameliorating, alleviating, or inhibiting progression of, pathogenic ocular neovascularization |
| US20110237605A1 (en) | 2010-03-26 | 2011-09-29 | Eric Phillips | Molecular Crystal of (4-(1,8-Naphthyridin-2-YL)Piperidin-1-YL)Pyrimidine Derivative |
| WO2015175954A1 (en) * | 2014-05-16 | 2015-11-19 | Scifluor Life Sciences, Inc. | Alpha v integrin antagonist compositions |
-
2019
- 2019-08-19 ES ES19192402T patent/ES2836733T3/es active Active
- 2019-08-19 EP EP19755380.3A patent/EP3837257A1/en not_active Withdrawn
- 2019-08-19 BR BR112021002839-0A patent/BR112021002839A2/pt not_active IP Right Cessation
- 2019-08-19 SM SM20200623T patent/SMT202000623T1/it unknown
- 2019-08-19 AU AU2019326932A patent/AU2019326932A1/en not_active Abandoned
- 2019-08-19 PL PL19192402.6T patent/PL3613739T3/pl unknown
- 2019-08-19 US US16/544,259 patent/US10703752B2/en not_active Expired - Fee Related
- 2019-08-19 DK DK19192402.6T patent/DK3613739T3/da active
- 2019-08-19 LT LTEP19192402.6T patent/LT3613739T/lt unknown
- 2019-08-19 MX MX2021001786A patent/MX2021001786A/es unknown
- 2019-08-19 RS RS20201460A patent/RS61182B1/sr unknown
- 2019-08-19 KR KR1020217007569A patent/KR20210057735A/ko not_active Ceased
- 2019-08-19 WO PCT/EP2019/072185 patent/WO2020043533A1/en not_active Ceased
- 2019-08-19 SG SG11202101424XA patent/SG11202101424XA/en unknown
- 2019-08-19 CN CN201980054419.6A patent/CN112805284A/zh active Pending
- 2019-08-19 JP JP2021532523A patent/JP7083073B2/ja not_active Expired - Fee Related
- 2019-08-19 US US17/268,406 patent/US20210198258A1/en not_active Abandoned
- 2019-08-19 SI SI201930011T patent/SI3613739T1/sl unknown
- 2019-08-19 CA CA3109326A patent/CA3109326A1/en active Pending
- 2019-08-19 HU HUE19192402A patent/HUE051802T2/hu unknown
- 2019-08-19 EP EP19192402.6A patent/EP3613739B1/en active Active
- 2019-08-19 MA MA053218A patent/MA53218A/fr unknown
-
2020
- 2020-11-25 CY CY20201101113T patent/CY1123871T1/el unknown
-
2021
- 2021-02-14 IL IL280857A patent/IL280857A/en unknown
- 2021-02-24 CO CONC2021/0002395A patent/CO2021002395A2/es unknown
- 2021-03-01 ZA ZA2021/01406A patent/ZA202101406B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202101424XA (en) | 2021-03-30 |
| JP7083073B2 (ja) | 2022-06-09 |
| CN112805284A (zh) | 2021-05-14 |
| JP2021534252A (ja) | 2021-12-09 |
| CO2021002395A2 (es) | 2021-07-30 |
| SI3613739T1 (sl) | 2021-02-26 |
| BR112021002839A2 (pt) | 2021-05-11 |
| EP3613739A1 (en) | 2020-02-26 |
| HUE051802T2 (hu) | 2021-03-29 |
| MA53218A (fr) | 2022-04-20 |
| MX2021001786A (es) | 2021-07-02 |
| EP3837257A1 (en) | 2021-06-23 |
| CA3109326A1 (en) | 2020-03-05 |
| WO2020043533A1 (en) | 2020-03-05 |
| RS61182B1 (sr) | 2021-01-29 |
| EP3613739B1 (en) | 2020-11-04 |
| ES2836733T3 (es) | 2021-06-28 |
| US20200055849A1 (en) | 2020-02-20 |
| ZA202101406B (en) | 2022-07-27 |
| US20210198258A1 (en) | 2021-07-01 |
| CY1123871T1 (el) | 2022-03-24 |
| SMT202000623T1 (it) | 2021-01-05 |
| DK3613739T3 (en) | 2020-12-07 |
| LT3613739T (lt) | 2021-02-25 |
| AU2019326932A1 (en) | 2021-03-18 |
| US10703752B2 (en) | 2020-07-07 |
| IL280857A (en) | 2021-04-29 |
| KR20210057735A (ko) | 2021-05-21 |
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