PL362903A1 - Inhibitory reniny - Google Patents

Inhibitory reniny

Info

Publication number: PL362903A1
Authority: PL; Poland
Prior art keywords: renin inhibitors; renin; inhibitors
Prior art date: 1999-04-27

Application number

PL00362903A

Other languages

English (en)

Inventor

Volker Breu

Daniel Bur

Hans-Peter Maerki

Eric Vieira

Wolfgang Wostl

Original Assignee

F.Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-27

Filing date

2000-04-20

Publication date

2004-11-02

2000-04-20 Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag

2004-11-02 Publication of PL362903A1 publication Critical patent/PL362903A1/pl

Links

239000002461 renin inhibitor Substances 0.000 title 1
229940086526 renin-inhibitors Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL00362903A 1999-04-27 2000-04-20 Inhibitory reniny PL362903A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99108200		1999-04-27
PCT/EP2000/003597 WO2000064887A1 (en)	1999-04-27	2000-04-20	Renin inhibitors

Publications (1)

Publication Number	Publication Date
PL362903A1 true PL362903A1 (pl)	2004-11-02

Family

ID=8238051

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00362903A PL362903A1 (pl)	1999-04-27	2000-04-20	Inhibitory reniny

Country Status (22)

Country	Link
US (1)	US6197959B1 (pl)
EP (1)	EP1180103B1 (pl)
JP (1)	JP3602449B2 (pl)
KR (1)	KR100476916B1 (pl)
CN (1)	CN1323079C (pl)
AR (1)	AR018717A1 (pl)
AT (1)	ATE363478T1 (pl)
AU (1)	AU761392B2 (pl)
BR (1)	BR0010076A (pl)
CA (1)	CA2370244C (pl)
CO (1)	CO5170512A1 (pl)
CZ (1)	CZ20013737A3 (pl)
DE (1)	DE60035039T2 (pl)
ES (1)	ES2286021T3 (pl)
HU (1)	HUP0200881A3 (pl)
MX (1)	MXPA01010855A (pl)
PE (1)	PE20010068A1 (pl)
PL (1)	PL362903A1 (pl)
SK (1)	SK15172001A3 (pl)
TR (1)	TR200103067T2 (pl)
WO (1)	WO2000064887A1 (pl)
ZA (1)	ZA200108739B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040214832A1 (en) *	2003-04-10	2004-10-28	Cuiman Cai	Piperazine derivative renin inhibitors
TW200513461A (en)	2003-10-01	2005-04-16	Speedel Experimenta Ag	Organische verbindungen
AR045950A1 (es) *	2003-10-09	2005-11-16	Speedel Experimenta Ag	Compuestos derivados de piperazina, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos.
DE602004022704D1 (de) *	2003-11-26	2009-10-01	Novartis Ag	4-phenylpiperidinderivate als renininhibitoren
TW200613274A (en) *	2004-07-09	2006-05-01	Speedel Experimenta Ag	Organic compounds
RU2407523C2 (ru)	2004-10-08	2010-12-27	Новартис Аг	Применение ингибиторов ренина для профилактики или лечения диастолической дисфункции или диастолической сердечной недостаточности
GB0428526D0 (en) *	2004-12-30	2005-02-09	Novartis Ag	Organic compounds
GB0500784D0 (en) *	2005-01-14	2005-02-23	Novartis Ag	Organic compounds
EP1707202A1 (de) *	2005-03-31	2006-10-04	Speedel Experimenta AG	Organische Verbindungen
WO2006103275A1 (en) *	2005-03-31	2006-10-05	Speedel Experimenta Ag	3,4,5-substituted piperidines as renin inhibitors
ES2352564T3 (es) *	2005-03-31	2011-02-21	Novartis Ag	Piperidinas sustituidas.
EP1897879A3 (en) *	2005-03-31	2008-06-11	Speedel Experimenta AG	2,4,5-substituted piperidines as renin inhibitors
TW200833687A (en) *	2005-03-31	2008-08-16	Speedel Experimenta Ag	Substituted piperidines
GB0508992D0 (en) *	2005-05-03	2005-06-08	Novartis Ag	Organic compounds
EP1885718B1 (en) *	2005-05-11	2017-03-15	Life Technologies Corporation	Fluorescent chemical compounds having high selectivity for double stranded dna, and methods for their use
AU2006253805A1 (en)	2005-05-27	2006-12-07	Actelion Pharmaceuticals Ltd.	Novel piperidine carboxylic acid amide derivatives
GB0514203D0 (en) *	2005-07-11	2005-08-17	Novartis Ag	Organic compounds
JP5306821B2 (ja) *	2005-12-30	2013-10-02	ノバルティスアーゲー	レニン阻害剤としての３，５−置換ピペリジン化合物
TW200804359A (en) *	2006-01-19	2008-01-16	Speedel Experimenta Ag	Substituted 4-phenylpiperidines
EP1908761A1 (en) *	2006-10-04	2008-04-09	Speedel Experimenta AG	Organic compounds
NZ582098A (en)	2007-06-25	2012-03-30	Novartis Ag	N5-(2-ethoxyethyl)-n3-(2-pyridinyl)-3,5-piperidinedicarboxamide derivatives for use as renin inhibitors
TW200934499A (en) *	2007-11-02	2009-08-16	Speedel Experimenta Ag	4,4-disubstituted piperidines
SG175877A1 (en) *	2009-05-04	2011-12-29	Plexxikon Inc	Compounds and methods for inhibition of renin, and indications therefor
WO2013045505A1 (en)	2011-09-28	2013-04-04	Novartis Ag	Biomarkers for raas combination therapy
EP2810644A1 (en)	2013-06-06	2014-12-10	Ferrer Internacional, S.A.	Oral formulation for the treatment of cardiovascular diseases
WO2018002673A1 (en)	2016-07-01	2018-01-04	N4 Pharma Uk Limited	Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL193686B1 (pl) *	1995-09-07	2007-03-30	Hoffmann La Roche	Pochodne piperydyny, środki lecznicze zawierającepochodne piperydyny, sposoby wytwarzania tych pochodnych oraz zastosowanie pochodnych

2000
- 2000-04-04 US US09/542,598 patent/US6197959B1/en not_active Expired - Fee Related
- 2000-04-20 EP EP00929401A patent/EP1180103B1/en not_active Expired - Lifetime
- 2000-04-20 CN CNB008067988A patent/CN1323079C/zh not_active Expired - Fee Related
- 2000-04-20 CZ CZ20013737A patent/CZ20013737A3/cs unknown
- 2000-04-20 KR KR10-2001-7013726A patent/KR100476916B1/ko not_active Expired - Fee Related
- 2000-04-20 WO PCT/EP2000/003597 patent/WO2000064887A1/en not_active Ceased
- 2000-04-20 HU HU0200881A patent/HUP0200881A3/hu unknown
- 2000-04-20 AU AU47501/00A patent/AU761392B2/en not_active Ceased
- 2000-04-20 BR BR0010076-5A patent/BR0010076A/pt not_active IP Right Cessation
- 2000-04-20 DE DE60035039T patent/DE60035039T2/de not_active Expired - Fee Related
- 2000-04-20 JP JP2000614239A patent/JP3602449B2/ja not_active Expired - Fee Related
- 2000-04-20 MX MXPA01010855A patent/MXPA01010855A/es active IP Right Grant
- 2000-04-20 AT AT00929401T patent/ATE363478T1/de not_active IP Right Cessation
- 2000-04-20 TR TR2001/03067T patent/TR200103067T2/xx unknown
- 2000-04-20 SK SK1517-2001A patent/SK15172001A3/sk unknown
- 2000-04-20 CA CA002370244A patent/CA2370244C/en not_active Expired - Fee Related
- 2000-04-20 PL PL00362903A patent/PL362903A1/pl unknown
- 2000-04-20 ES ES00929401T patent/ES2286021T3/es not_active Expired - Lifetime
- 2000-04-24 PE PE2000000377A patent/PE20010068A1/es not_active Application Discontinuation
- 2000-04-25 CO CO00029684A patent/CO5170512A1/es not_active Application Discontinuation
- 2000-04-25 AR ARP000101933A patent/AR018717A1/es active IP Right Grant
2001
- 2001-10-23 ZA ZA200108739A patent/ZA200108739B/en unknown

Also Published As

Publication number	Publication date
CN1349524A (zh)	2002-05-15
CO5170512A1 (es)	2002-06-27
KR20020005017A (ko)	2002-01-16
DE60035039T2 (de)	2008-02-07
KR100476916B1 (ko)	2005-03-17
WO2000064887A1 (en)	2000-11-02
MXPA01010855A (es)	2002-05-06
DE60035039D1 (de)	2007-07-12
AU4750100A (en)	2000-11-10
CA2370244C (en)	2007-03-27
CZ20013737A3 (cs)	2002-04-17
US6197959B1 (en)	2001-03-06
TR200103067T2 (tr)	2002-05-21
AR018717A1 (es)	2001-11-28
JP3602449B2 (ja)	2004-12-15
ES2286021T3 (es)	2007-12-01
CN1323079C (zh)	2007-06-27
SK15172001A3 (sk)	2002-06-04
BR0010076A (pt)	2002-01-15
EP1180103B1 (en)	2007-05-30
PE20010068A1 (es)	2001-01-29
ATE363478T1 (de)	2007-06-15
HUP0200881A2 (en)	2002-08-28
ZA200108739B (en)	2003-01-23
JP2002543072A (ja)	2002-12-17
EP1180103A1 (en)	2002-02-20
HUP0200881A3 (en)	2003-05-28
AU761392B2 (en)	2003-06-05
CA2370244A1 (en)	2000-11-02

Legal Events

Date	Code	Title	Description
2008-11-28	DISC	Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
EG23979A (en)	2008-02-27	Renin inhibitors
GB9900416D0 (en)	1999-02-24	Inhibitors
IL148820A0 (en)	2002-09-12	Fab i inhibitors
GB9912961D0 (en)	1999-08-04	Metalloprotease inhibitors
DE60035039D1 (de)	2007-07-12	Renin inhibitoren
IL145085A0 (en)	2002-06-30	Dihetero-substituted metalloprotease inhibitors
EP1235577A4 (en)	2003-04-09	PROTEASE INHIBITORS
EP1153022A4 (en)	2002-03-27	PROTEASE INHIBITORS
GB9924522D0 (en)	1999-12-15	Enzyme inhibitors
EP1232155A4 (en)	2002-11-20	PROTEASE INHIBITORS
EP1229915A4 (en)	2003-05-14	PROTEASE INHIBITORS
EP1229912A4 (en)	2003-05-07	PROTEASE INHIBITORS
EP1231921A4 (en)	2004-06-23	PROTEASE INHIBITORS
EP1229914A4 (en)	2004-06-23	PROTEASE INHIBITORS
EP1233771A4 (en)	2003-05-14	PROTEASE INHIBITORS
EP1229911A4 (en)	2003-05-07	PROTEASE INHIBITORS
EP1351930A4 (en)	2004-09-15	PROTEASE INHIBITORS
EP1173429A4 (en)	2002-06-19	PROTEASE INHIBITORS
EP1161237A4 (en)	2002-03-27	PROTEASE INHIBITORS
EP1231923A4 (en)	2003-05-14	PROTEASE INHIBITORS
GB2389113B (en)	2004-02-04	B-secretase inhibitor
EP1232154A4 (en)	2004-06-23	PROTEASE INHIBITORS
EP1231922A4 (en)	2004-06-23	PROTEASE INHIBITORS
GB9917294D0 (en)	1999-09-22	Inhibitors
GB9900413D0 (en)	1999-02-24	Inhibitors