PL365808A1 - Usuwanie plazmin (ogenu) z roztworów białkowych - Google Patents

Usuwanie plazmin (ogenu) z roztworów białkowych

Info

Publication number
PL365808A1
PL365808A1 PL02365808A PL36580802A PL365808A1 PL 365808 A1 PL365808 A1 PL 365808A1 PL 02365808 A PL02365808 A PL 02365808A PL 36580802 A PL36580802 A PL 36580802A PL 365808 A1 PL365808 A1 PL 365808A1
Authority
PL
Poland
Prior art keywords
plasmin
ogen
amino acid
removal
protein solutions
Prior art date
Application number
PL02365808A
Other languages
English (en)
Other versions
PL205685B1 (pl
Inventor
Israel Nur
Liliana Bar
Malkit Azachi
Original Assignee
Omrix Biopharmaceuticals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharmaceuticals S.A. filed Critical Omrix Biopharmaceuticals S.A.
Publication of PL365808A1 publication Critical patent/PL365808A1/pl
Publication of PL205685B1 publication Critical patent/PL205685B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
PL365808A 2001-05-21 2002-05-17 Sposób in vitro usuwania lub wyodrębniania plazminogenu lub plazminy w obecności fibrynogenu, stałe podłoże powinowactwa do oczyszczania mieszaniny zawierającej fibrynogen i plazminę i/lub plazminogen oraz krioprecypitat PL205685B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29196801P 2001-05-21 2001-05-21
EP01115157 2001-06-21

Publications (2)

Publication Number Publication Date
PL365808A1 true PL365808A1 (pl) 2005-01-10
PL205685B1 PL205685B1 (pl) 2010-05-31

Family

ID=26076623

Family Applications (1)

Application Number Title Priority Date Filing Date
PL365808A PL205685B1 (pl) 2001-05-21 2002-05-17 Sposób in vitro usuwania lub wyodrębniania plazminogenu lub plazminy w obecności fibrynogenu, stałe podłoże powinowactwa do oczyszczania mieszaniny zawierającej fibrynogen i plazminę i/lub plazminogen oraz krioprecypitat

Country Status (19)

Country Link
US (4) US20040197891A1 (pl)
EP (1) EP1390485B1 (pl)
JP (1) JP4385097B2 (pl)
KR (1) KR100871454B1 (pl)
AT (1) ATE342353T1 (pl)
AU (1) AU2002314081B2 (pl)
CA (1) CA2447789C (pl)
CZ (1) CZ20033097A3 (pl)
DE (1) DE60215338T2 (pl)
EE (1) EE05485B1 (pl)
ES (1) ES2274044T3 (pl)
HU (1) HU228899B1 (pl)
IL (2) IL158754A0 (pl)
MX (1) MXPA03010616A (pl)
PL (1) PL205685B1 (pl)
RU (2) RU2344143C2 (pl)
SK (1) SK288005B6 (pl)
WO (1) WO2002095019A1 (pl)
ZA (1) ZA200309030B (pl)

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US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
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US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US7704453B2 (en) 2007-06-07 2010-04-27 Ethicon, Inc. Method for establishing a sterilizing dose for radiation sensitive products
US8409499B2 (en) 2007-06-07 2013-04-02 Ethicon, Inc. Method for establishing a sterilizing dose for radiation sensitive products
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WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
WO2010032246A2 (en) 2008-09-22 2010-03-25 Omrix Biopharmaceuticals Ltd. Implantable device comprising a substrate pre-coated with stabilized fibrin
JP5805542B2 (ja) * 2009-02-20 2015-11-04 オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． 少なくとも２成分の薬物を投与する装置
WO2011092694A2 (en) 2010-01-28 2011-08-04 Omrix Biopharmaceuticals Ltd. Method for improved fibrin sealing
SG10201503899SA (en) * 2010-05-18 2015-06-29 Abbvie Inc Apparatus And Process Of Purification Of Proteins
IL207586A0 (en) 2010-08-12 2010-12-30 Omrix Biopharmaceuticals Ltd A fibrin based therapeutic preparation and use thereof
JP5836577B2 (ja) * 2010-09-14 2015-12-24 株式会社カネカ クリングル配列を有する蛋白質またはペプチドを精製または除去するアフィニティ担体の製造方法、その精製方法、除去方法
WO2012036140A1 (ja) * 2010-09-14 2012-03-22 株式会社カネカ クリングル配列を有する蛋白質またはペプチドを精製または除去するアフィニティ担体、及びそれを用いた精製方法、除去方法
RU2603103C2 (ru) * 2010-09-20 2016-11-20 Октафарма Аг Способ получения фибриногена с использованием сильной анионообменной смолы и содержащий фибриноген продукт
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
IL213375A0 (en) 2011-06-05 2011-07-31 Omrix Biopharmaceuticals Device for spraying fluids in proximity to a surface
CA2840568C (en) 2011-06-27 2021-05-04 Emory University Compositions, uses, and preparation of platelet lysates
IL213864A0 (en) 2011-06-30 2011-08-31 Omrix Biopharmaceuticals Ltd Method for removing a lytic enzyme from a heterogeneous mixture
CA3078563A1 (en) 2011-12-29 2013-07-04 Omrix Biopharmaceuticals Ltd. Method and device for fast dissolution of solid protein composition
US10130346B2 (en) 2012-07-24 2018-11-20 Omrix Biopharmaceuticals Ltd. Device and method for the application of a curable fluid composition to a bodily organ
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
AU2013365623B2 (en) 2012-12-20 2017-08-24 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
BR112015015703A2 (pt) 2012-12-30 2020-02-04 Omrix Biopharmaceuticals Ltd dispositivo e método para a aplicação de uma composição fluida curável a uma porção de um órgão do corpo
USD754325S1 (en) 2013-06-06 2016-04-19 Omrix Biopharmaceuticals Ltd. Device of a curable fluid composition to a bodily organ
IL230151A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing a polymerization inhibitor
IL230150A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing zymogens
IL231230A0 (en) 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation
IL231792A0 (en) 2014-03-27 2014-08-31 Omrix Biopharmaceuticals Ltd Device and method for the preparation and administration of one-component fibrin glue
IL234246A0 (en) 2014-08-21 2014-11-30 Omrix Biopharmaceuticals Ltd Stabilized thrombin
BR112017010250A2 (pt) 2014-11-18 2018-01-02 Omrix Biopharmaceuticals Ltd aparelho para secagem por aspersão e método de uso do mesmo
IL235751A0 (en) 2014-11-18 2015-02-26 Omrix Biopharmaceuticals Ltd An addition to the spray dryer
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
EP3258945B1 (en) 2015-02-16 2020-10-07 Nayacure Therapeutics Ltd. Modified blood clots
US10066224B2 (en) 2015-02-25 2018-09-04 Omrix Biopharmaceuticals Ltd. Method for purifying and quantifying thrombin and its degradation polypeptides
IL242984A0 (en) 2015-12-08 2016-02-29 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, their preparation and how to use them
US10159720B2 (en) 2015-12-08 2018-12-25 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, preparation and uses thereof
BR112018009459A8 (pt) 2015-11-11 2019-02-26 Ethicon Inc formulação de selante e usos da mesma
IL242924A0 (en) 2015-12-03 2016-04-21 Omrix Biopharmaceuticals Ltd Syringe system for storing and mixing two ingredients
CN109789162A (zh) * 2016-09-01 2019-05-21 普拉斯富瑞有限公司 具有降低的纤溶活性的人类血液源产品及其在止血障碍中的用途
IT201600091964A1 (it) * 2016-09-13 2018-03-13 Kedrion Spa Processo per la purificazione del plasminogeno a partire da plasma umano.
IL247821A0 (en) 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Adhesive preparations and their use
KR102640024B1 (ko) * 2017-03-09 2024-02-22 프리비파하르마, 컨설팅 게엠베하 혈액 분획으로부터의 Glu-플라스미노겐의 제조 및 용도
IL256405A (en) 2017-12-19 2018-01-31 Omrix Biopharmaceuticals Ltd Wound bandage and method for its production
IL317026A (en) * 2018-02-28 2025-01-01 Plas Free Ltd In vitro device and matrix for removing fibrinolytic proteins from biological fluids, methods and uses thereof
IL263679A (en) 2018-12-12 2019-03-31 Omrix Biopharmaceuticals Ltd Kits, methods, and compositions for preventing tissue adhesion
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CN111760556B (zh) * 2020-07-09 2023-06-30 江苏尤里卡生物科技有限公司 一种尿激酶吸附剂及其制备方法和应用
JP2025512143A (ja) 2020-11-09 2025-04-17 武田薬品工業株式会社 酸化ケイ素吸着を使用する血漿からのｆｖｉｉｉの精製
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Also Published As

Publication number Publication date
CZ20033097A3 (cs) 2004-06-16
ATE342353T1 (de) 2006-11-15
KR20040011503A (ko) 2004-02-05
DE60215338T2 (de) 2007-05-16
CA2447789A1 (en) 2002-11-28
ZA200309030B (en) 2005-06-29
JP2004528853A (ja) 2004-09-24
RU2344143C2 (ru) 2009-01-20
PL205685B1 (pl) 2010-05-31
RU2458067C2 (ru) 2012-08-10
US20030124703A1 (en) 2003-07-03
US7641918B2 (en) 2010-01-05
DE60215338D1 (de) 2006-11-23
IL158754A0 (en) 2004-05-12
HK1060902A1 (en) 2004-08-27
IL158754A (en) 2009-05-04
US8563288B2 (en) 2013-10-22
SK288005B6 (sk) 2012-10-02
US20070092959A1 (en) 2007-04-26
KR100871454B1 (ko) 2008-12-03
US20090176293A1 (en) 2009-07-09
US7125569B2 (en) 2006-10-24
CA2447789C (en) 2012-11-06
RU2008130356A (ru) 2010-01-27
ES2274044T3 (es) 2007-05-16
RU2003136746A (ru) 2005-05-20
MXPA03010616A (es) 2004-04-02
JP4385097B2 (ja) 2009-12-16
WO2002095019A1 (en) 2002-11-28
AU2002314081B2 (en) 2007-04-05
EE200300578A (et) 2004-02-16
EP1390485B1 (en) 2006-10-11
US20040197891A1 (en) 2004-10-07
HUP0600110A2 (en) 2006-05-29
HU228899B1 (en) 2013-06-28
EE05485B1 (et) 2011-10-17
EP1390485A1 (en) 2004-02-25
SK14202003A3 (sk) 2004-08-03
HUP0600110A3 (en) 2010-01-28

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